{"product_id":"clindamycin-and-benzoyl-peroxide-gel-1-5","title":"Clindamycin and Benzoyl Peroxide Gel 1%\/5%","description":"\u003cdiv class=\"pp\" lang=\"en\" itemscope itemtype=\"https:\/\/schema.org\/Product\"\u003e\n  \u003cmeta itemprop=\"name\" content=\"Perrigo Clindamycin and Benzoyl Peroxide Gel 1%\/5%\"\u003e\n  \u003cmeta itemprop=\"brand\" content=\"Perrigo\"\u003e\n  \u003cmeta itemprop=\"category\" content=\"Skincare \u0026gt; Acne Treatment\"\u003e\n  \u003cmeta itemprop=\"countryOfOrigin\" content=\"Various\"\u003e\n\n  \u003cscript type=\"application\/ld+json\"\u003e{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"FAQPage\",\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Clindamycin and Benzoyl Peroxide Gel 1%\/5% pregnancy and breastfeeding safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"This product should only be used during pregnancy under the explicit guidance of a physician or OB-GYN. Clindamycin Phosphate is FDA Pregnancy Category B — animal studies have not demonstrated fetal risk, but there are no adequate, well-controlled studies in pregnant women. Benzoyl Peroxide has very low systemic absorption (\u0026lt;2%), but safety in pregnancy has not been formally established. During breastfeeding, avoid applying the gel to the chest or breast area to prevent any possibility of infant ingestion. The safest approach is to consult your dermatologist and OB-GYN before starting or continuing this medication during pregnancy or lactation.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Clindamycin and Benzoyl Peroxide Gel 1%\/5% fungal acne (malassezia) safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Yes, this formula is generally considered safe for those prone to fungal acne (Malassezia folliculitis). The ingredient list contains no fatty acids in the C11–C24 range that Malassezia feeds on. The diheptyl sodium sulfosuccinate present in the Perrigo formula uses short C7 heptyl chains that fall below the carbon chain length required to feed Malassezia. Additionally, Benzoyl Peroxide itself has well-documented antifungal activity and has been used as a treatment for Malassezia-related conditions. If you are uncertain, consult your dermatologist who prescribed this medication.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can I use Clindamycin and Benzoyl Peroxide Gel with retinol, vitamin C, AHA, or BHA?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Proceed with caution and physician guidance before layering this medication with other topical actives. Combining with AHA (glycolic\/lactic acid), BHA (salicylic acid), or retinoids (retinol, tretinoin, adapalene) significantly increases the risk of skin irritation, excessive dryness, peeling, and barrier damage — especially in the first weeks of treatment. Many dermatologists recommend starting with this gel alone, building skin tolerance over 4–6 weeks, and then carefully introducing other actives if needed. Vitamin C (ascorbic acid) is generally lower-risk but should still be used at a separate time of day. Do not use with erythromycin-containing products — they may counteract the antibacterial activity of clindamycin.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What skin type is Clindamycin and Benzoyl Peroxide Gel 1%\/5% best for?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"This prescription gel is best suited for oily and acne-prone skin types dealing with mild to moderately severe inflammatory acne vulgaris (papules, pustules). It performs excellently on oily skin because the oil-free aqueous gel texture absorbs quickly without adding shine. Combination skin also responds very well. Dry and sensitive skin types can use it, but they require more diligent moisturization and a gradual build-up in frequency (starting every other day) to prevent excessive dryness and irritation. It is not recommended as a first-choice option for purely non-inflammatory or comedonal-only acne — adapalene-based products may be more effective in those cases.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long until I see results from Clindamycin and Benzoyl Peroxide Gel 1%\/5%?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Results vary by individual, but here is a general timeline based on clinical data and patient experience: Days 1–14: Adjustment phase — possible initial dryness, redness, or minor purging as skin adapts to BPO. Some users see early improvement in surface pustules within the first week. Weeks 2–4: Reduction in the frequency of new breakouts as clindamycin suppresses bacterial load. Weeks 4–8: Visible reduction in inflammatory lesions; skin texture begins to improve. Weeks 8–12: Peak efficacy per clinical trials — up to 69% of patients report a positive outcome by week 10. Do not discontinue early due to initial irritation; the most meaningful results come after sustained use. Consult your dermatologist if you see no improvement after 8 weeks.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Where does Clindamycin and Benzoyl Peroxide Gel go in my skincare routine?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Apply this gel as your first treatment step after cleansing and fully drying your skin. The correct routine order is: (1) Gentle non-medicated cleanser → (2) Pat dry, wait 15 minutes → (3) Apply this gel to the entire face in a thin layer → (4) Let absorb for 30 seconds → (5) Non-comedogenic moisturizer → (6) SPF 30+ sunscreen in the morning. Non-medicated makeup may be applied approximately 1 hour after the gel. Do not layer other topical acne medications unless directed by your physician. This gel is applied twice daily — morning and evening — for the 1%\/5% formulation.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Clindamycin and Benzoyl Peroxide Gel comedogenic — will it clog pores?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No — this formulation has a comedogenic rating of 0\/5. It is an oil-free aqueous gel with no comedogenic oils, waxes, or heavy silicones. The active ingredients (clindamycin and benzoyl peroxide) actually work to unclog pores by reducing bacterial populations and promoting gentle desquamation (skin cell shedding). The inactive ingredients — propylene glycol, carbon, diheptyl sodium sulfosuccinate, and water — are all non-comedogenic. This product was specifically designed for acne-prone skin and is a standard dermatologist prescription precisely because it does not aggravate existing blockages.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long does Clindamycin and Benzoyl Peroxide Gel 1%\/5% last after opening?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"This gel has a Period After Opening (PAO) of approximately 3 months (90 days) after dispensing by the pharmacy. After this point, the stability and potency of the active ingredients — particularly benzoyl peroxide, which can degrade over time — may be compromised. The 50g jar used twice daily on the face should be largely consumed within this window for typical adult acne treatment. Always check the expiration date label your pharmacist provides. Store at room temperature (68–77°F \/ 20–25°C), away from moisture and heat, and do not freeze. Discard any unused product after the expiration date.\"\n          }\n        }\n      ]\n    },\n    {\n      \"@type\": \"HowTo\",\n      \"name\": \"How to use Perrigo Clindamycin and Benzoyl Peroxide Gel 1%\/5%\",\n      \"totalTime\": \"PT2M\",\n      \"step\": [\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 1,\n          \"name\": \"Cleanse Gently\",\n          \"text\": \"Wash your face with a mild, non-medicated cleanser using only your hands — avoid abrasive scrubs or exfoliating cleansers. Rinse thoroughly with warm water and pat dry.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 2,\n          \"name\": \"Wait 15 Minutes\",\n          \"text\": \"Allow skin to fully dry before applying the gel. Applying to damp skin can increase irritation and erythema, especially during the initial weeks of treatment.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 3,\n          \"name\": \"Apply a Thin Layer\",\n          \"text\": \"Dispense a small pea-sized amount and spread a thin, even layer over the entire affected area. Avoid the eyes, lips, nostrils, and any mucous membranes or broken skin.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 4,\n          \"name\": \"Allow to Absorb\",\n          \"text\": \"Let the gel absorb fully — approximately 30 seconds. Do not rinse off. Resist the urge to apply more product to stubborn areas; excess application increases dryness without added benefit.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 5,\n          \"name\": \"Follow with Moisturizer\",\n          \"text\": \"Apply a non-comedogenic, oil-free moisturizer to minimize dryness and peeling. Products such as Cetaphil, CeraVe, or La Roche-Posay Toleriane are commonly recommended by dermatologists with this medication.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 6,\n          \"name\": \"Apply SPF in the Morning\",\n          \"text\": \"Benzoyl Peroxide increases photosensitivity. Apply a broad-spectrum SPF 30 or higher sunscreen every morning as the final step. Reapply every 2 hours if outdoors. Non-medicated makeup may be applied 1 hour after the gel.\"\n        }\n      ]\n    },\n    {\n      \"@type\": \"ItemList\",\n      \"name\": \"Perrigo Clindamycin and Benzoyl Peroxide Gel 1%\/5% — Ingredients (INCI)\",\n      \"numberOfItems\": 9,\n      \"itemListElement\": [\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 1,\n          \"name\": \"Benzoyl Peroxide (5%)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 2,\n          \"name\": \"Clindamycin Phosphate (1%)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 3,\n          \"name\": \"Carbon\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 4,\n          \"name\": \"Diheptyl Sodium Sulfosuccinate\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 5,\n          \"name\": \"Limonene\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          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24\"\u003e\u003cpath d=\"M20 8l-8-4-8 4v8l8 4 8-4V8z\"\u003e\u003c\/path\u003e\u003cline x1=\"4\" y1=\"8\" x2=\"20\" y2=\"8\"\u003e\u003c\/line\u003e\u003cline x1=\"12\" y1=\"12\" x2=\"12\" y2=\"20\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-calendar\" viewbox=\"0 0 24 24\"\u003e\u003crect x=\"3\" y=\"5\" width=\"18\" height=\"16\" rx=\"2\"\u003e\u003c\/rect\u003e\u003cline x1=\"3\" y1=\"10\" x2=\"21\" y2=\"10\"\u003e\u003c\/line\u003e\u003cline x1=\"8\" y1=\"3\" x2=\"8\" y2=\"7\"\u003e\u003c\/line\u003e\u003cline x1=\"16\" y1=\"3\" x2=\"16\" y2=\"7\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-home\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M3 11l9-7 9 7v9a2 2 0 01-2 2h-4v-7H9v7H5a2 2 0 01-2-2v-9z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-plane\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M22 12l-9 4-3 6-2-5-5-2 6-3 4-9 9 9z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-arrow-right\" viewbox=\"0 0 24 24\"\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003cpolyline points=\"12 5 19 12 12 19\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n    \u003c\/defs\u003e\n  \u003c\/svg\u003e\n\n  \n  \u003csection id=\"pp-overview\" class=\"pp-hero\" aria-labelledby=\"pp-hero-title\"\u003e\n    \u003ch2 id=\"pp-hero-title\" class=\"pp-sr-only\" style=\"position:absolute;left:-10000px\"\u003eProduct overview\u003c\/h2\u003e\n    \u003cdiv class=\"pp-origin\"\u003e\n      \u003csvg class=\"pin\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-pin\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n      \u003cspan class=\"text\"\u003eMade in Various\u003c\/span\u003e\n      \u003cspan class=\"dot\"\u003e\u003c\/span\u003e\n      \u003cspan class=\"tag\"\u003eINTERNATIONAL\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"pp-subtitle\"\u003eA prescription-strength topical combination gel delivering 1% Clindamycin Phosphate and 5% Benzoyl Peroxide — fighting acne-causing bacteria through dual mechanisms, reducing inflammation, and unclogging pores for clinically proven clearer skin. FDA-approved for mild to moderately severe acne vulgaris in patients 12 and older.\u003c\/p\u003e\n    \u003cdiv class=\"pp-badges\"\u003e\n\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e FDA-Approved\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Prescription Strength\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Dual-Action Formula\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Clinically Tested\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Non-Comedogenic\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Oil-Free Gel\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Reduces Antibiotic Resistance\u003c\/span\u003e\n\u003c\/div\u003e\n    \u003cnav class=\"pp-nav\" aria-label=\"Jump to product section\"\u003e\n      \u003cdiv class=\"pp-nav-head\"\u003eJump to section\u003c\/div\u003e\n      \u003cdiv class=\"pp-nav-list\"\u003e\n        \u003ca href=\"#pp-safety\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSafety\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-ingredients\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eIngredients\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-routine\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-refresh\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eRoutine\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-how-to-use\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eHow to use\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-skin-types\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSkin types\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-results\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-trending\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eResults\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-reviews\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-star\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eReviews\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-dupes\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-coin\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eDupes\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-faq\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-help\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eFAQ\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/nav\u003e\n    \n    \u003cdiv class=\"pp-scorecard\"\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003ePregnancy\u003c\/div\u003e\n\u003cdiv class=\"val caution\"\u003e\n\u003csvg class=\"alert\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Caution\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eFungal Acne\u003c\/div\u003e\n\u003cdiv class=\"val safe\"\u003e\n\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Yes\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eComedogenic\u003c\/div\u003e\n\u003cdiv class=\"val safe\"\u003e0\/5\u003c\/div\u003e\n\u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pp-specs\"\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eOrigin\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eUSA\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eType\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eRx Topical Gel\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eSize\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e50g Jar\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eKey Actives\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eClinda 1% + BPO 5%\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-calendar\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003ePAO\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e3 Months\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n    \n    \u003cdiv class=\"pp-videos\"\u003e\n      \u003cspan class=\"eyebrow\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-star\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Real reviews · YouTube Shorts\u003c\/span\u003e\n      \u003cdiv class=\"pp-videos-grid\"\u003e\n        \u003cdiv class=\"pp-videos-frame\"\u003e\n          \u003ciframe src=\"https:\/\/www.youtube.com\/embed\/LYCXxA5mtp0?modestbranding=1\u0026amp;rel=0\u0026amp;playsinline=1\" title=\"YouTube Shorts review 1 — Perrigo Clindamycin and Benzoyl Peroxide Gel 1%\/5%\" loading=\"lazy\" allow=\"accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share; fullscreen\" allowfullscreen referrerpolicy=\"strict-origin-when-cross-origin\"\u003e\u003c\/iframe\u003e\n        \u003c\/div\u003e\n\u003cdiv class=\"pp-videos-frame\"\u003e\n          \u003ciframe src=\"https:\/\/www.youtube.com\/embed\/1jpyFQIP-_w?modestbranding=1\u0026amp;rel=0\u0026amp;playsinline=1\" title=\"YouTube Shorts review 2 — Perrigo Clindamycin and Benzoyl Peroxide Gel 1%\/5%\" loading=\"lazy\" allow=\"accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share; fullscreen\" allowfullscreen referrerpolicy=\"strict-origin-when-cross-origin\"\u003e\u003c\/iframe\u003e\n        \u003c\/div\u003e\n\u003cdiv class=\"pp-videos-frame\"\u003e\n          \u003ciframe src=\"https:\/\/www.youtube.com\/embed\/_RjpT3v42Pg?modestbranding=1\u0026amp;rel=0\u0026amp;playsinline=1\" title=\"YouTube Shorts review 3 — Perrigo Clindamycin and Benzoyl Peroxide Gel 1%\/5%\" loading=\"lazy\" allow=\"accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share; fullscreen\" allowfullscreen referrerpolicy=\"strict-origin-when-cross-origin\"\u003e\u003c\/iframe\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n    \n    \u003cdiv class=\"pp-highlight\"\u003e\n      \u003cspan class=\"eyebrow\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Why it's different\u003c\/span\u003e\n      \u003ch3\u003eDual Antibacterial Action\u003c\/h3\u003e\n      \u003cp\u003eClindamycin inhibits bacterial protein synthesis while Benzoyl Peroxide releases oxygen radicals that kill P. acnes bacteria — two mechanisms working simultaneously.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n\n  \u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-sensory\"\u003e\n\u003cspan class=\"eyebrow\"\u003e01\u003c\/span\u003e\u003ch2\u003eTexture \u0026amp; feel\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSENSORY\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-sensory\"\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eConsistency\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eLightweight Aqueous Gel\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-wind\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eScent\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eFaint Medicinal \/ Citrus\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eAbsorption\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eFast, ~30 seconds\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eFinish\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eMatte \/ Dry\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-features\"\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eDual Antibacterial Action\u003c\/h4\u003e\n\u003cp\u003eClindamycin inhibits bacterial protein synthesis while Benzoyl Peroxide releases oxygen radicals that kill P. acnes bacteria — two mechanisms working simultaneously.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eReduces Antibiotic Resistance\u003c\/h4\u003e\n\u003cp\u003eBenzoyl Peroxide actively counteracts the development of clindamycin-resistant bacterial strains — a major advantage over using clindamycin alone.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eAnti-Inflammatory Effect\u003c\/h4\u003e\n\u003cp\u003eClindamycin suppresses PMN chemotaxis in vitro, reducing inflammatory cascade. Clinical studies show significant reduction of inflammatory lesions within 10 weeks.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003ePore-Clearing Keratolytic\u003c\/h4\u003e\n\u003cp\u003eBenzoyl Peroxide concentrates into lipid-rich sebaceous follicles and promotes gentle desquamation, helping to unclog blocked pores and prevent comedone formation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eClinically Proven Formula\u003c\/h4\u003e\n\u003cp\u003eDemonstrated superiority over vehicle, clindamycin alone, and benzoyl peroxide alone in two adequate and well-controlled clinical studies of 758 patients.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eOil-Free, Non-Greasy Gel\u003c\/h4\u003e\n\u003cp\u003eWater-based aqueous gel formula leaves no residue or shine. Compatible with non-medicated makeup applied one hour after application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-safety\"\u003e\n\u003cspan class=\"eyebrow\"\u003e02\u003c\/span\u003e\u003ch2\u003eSafety \u0026amp; compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSAFE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePregnancy Safety — Use With Caution\u003c\/strong\u003e\n\u003cp\u003eClindamycin Phosphate is FDA Category B (animal studies showed no risk; no adequate human studies). Benzoyl Peroxide has minimal systemic absorption (\u0026lt;2%). Always consult your OB-GYN or dermatologist before use during pregnancy. Avoid applying to chest\/breast area if breastfeeding.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eBreastfeeding — Physician Guidance Required\u003c\/strong\u003e\n\u003cp\u003eDo not apply to the chest or breast area to prevent infant ingestion. Systemic absorption is \u0026lt;1% for clindamycin. Consult your doctor before use while breastfeeding.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eFungal Acne (Malassezia) — Generally Safe\u003c\/strong\u003e\n\u003cp\u003eContains no C11–C24 fatty acids or problematic esters. Benzoyl Peroxide has documented antifungal activity against Malassezia. The diheptyl sodium sulfosuccinate (C7 chains) falls below the carbon chain length that feeds Malassezia.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eComedogenic Rating — 0\/5 (Non-Comedogenic)\u003c\/strong\u003e\n\u003cp\u003eContains no oils, silicones, or high-comedogenic ingredients. Oil-free aqueous gel base is suitable for oily and acne-prone skin without clogging pores.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sun\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSun Sensitivity — Increased Photosensitivity\u003c\/strong\u003e\n\u003cp\u003eBenzoyl Peroxide can increase sensitivity to sunlight and UV radiation. Minimize sun exposure after application. Use protective clothing and broad-spectrum SPF 30+ sunscreen daily. Avoid tanning beds and sunlamps.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-leaf\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSensitive Skin — Proceed Carefully\u003c\/strong\u003e\n\u003cp\u003eMay cause dryness, peeling, erythema, burning, or itching — especially in the first 2–4 weeks. Start with once-daily application and use a gentle non-comedogenic moisturizer. Discontinue and consult a physician if severe irritation occurs.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eContraindications — Do Not Use If:\u003c\/strong\u003e\n\u003cp\u003eHistory of regional enteritis, ulcerative colitis, pseudomembranous colitis, or antibiotic-associated colitis. Hypersensitivity to clindamycin, lincomycin, benzoyl peroxide, or any formula component. Not for oral, ophthalmic, or intravaginal use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eFabric Bleaching Warning\u003c\/strong\u003e\n\u003cp\u003eBenzoyl Peroxide will bleach hair, colored fabrics, furniture, and carpeting on contact. Allow gel to fully absorb before contact with clothing, pillowcases, and towels. Use white or old linens while on treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-ingredients\"\u003e\n\u003cspan class=\"eyebrow\"\u003e03\u003c\/span\u003e\u003ch2\u003eIngredient breakdown\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eINGREDIENTS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eClindamycin Phosphate 1%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA water-soluble phosphate ester of the semisynthetic lincosamide antibiotic clindamycin, specifically chosen for topical acne treatment. Once on the skin, phosphatase enzymes convert clindamycin phosphate to its active form, clindamycin base, which then penetrates into sebaceous follicles.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism:\u003c\/strong\u003e Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking peptide-bond formation in Cutibacterium acnes (formerly P. acnes).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory:\u003c\/strong\u003e Suppresses complement-derived chemotaxis of polymorphonuclear leukocytes (PMNs) in vitro, reducing inflammatory lesion count.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBioavailability:\u003c\/strong\u003e Mean systemic absorption is \u0026lt;1%, minimizing systemic antibiotic side effects compared to oral clindamycin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical Data:\u003c\/strong\u003e In controlled trials, twice-daily application for 10–16 weeks reduced inflammatory lesions significantly more than vehicle or clindamycin alone.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eUse beyond 12 weeks has not been evaluated. Do not use concurrently with erythromycin-containing products — they may antagonize each other's antibacterial activity. Prolonged antibiotic use may promote resistant strains; BPO in this formula mitigates that risk.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eBenzoyl Peroxide 5%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eAn organic peroxide and the most widely studied OTC-to-Rx acne active. BPO releases free radical oxygen intermediates that directly kill bacteria without inducing antibiotic resistance — a key advantage when combined with antibiotics. Its lipophilic nature allows it to concentrate within sebaceous follicles where acne bacteria proliferate.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eBactericidal Mechanism:\u003c\/strong\u003e Oxidized intermediates interact with bacterial cell membranes and proteins, killing C. acnes without the resistance risk associated with antibiotics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeratolytic:\u003c\/strong\u003e Promotes gentle shedding of dead skin cells (desquamation), helping to clear blocked pores and reduce comedone formation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Resistance:\u003c\/strong\u003e BPO actively prevents clindamycin-resistant P. acnes strains from developing — critical for long-term treatment efficacy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Safety:\u003c\/strong\u003e \u0026lt;2% enters systemic circulation as benzoic acid, which is rapidly excreted. No systemic accumulation has been observed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eBPO bleaches fabric, hair, and surfaces on contact. It can increase photosensitivity — always pair morning application with SPF 30+ sunscreen. Avoid contact with eyes, lips, and mucous membranes. May cause initial purging or increased dryness in weeks 1–2.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-leaf\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003ePropylene Glycol Inactive\u003cspan class=\"tag supporting\"\u003eFunctional\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA humectant and solvent that helps maintain the gel's consistency, aids in active ingredient delivery, and provides a degree of hydration to offset the drying effects of BPO. Also acts as a preservative co-solvent.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eComedogenic Rating:\u003c\/strong\u003e 0\/5 — safe for acne-prone skin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFungal Acne Safe:\u003c\/strong\u003e Yes — not a fatty acid ester.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFunction:\u003c\/strong\u003e Humectant, solvent, penetration enhancer for actives.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-callout positive\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eGenerally well-tolerated. Rare contact sensitivity occurs in a small subset of individuals with propylene glycol allergy.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eLimonene Inactive\u003cspan class=\"tag supporting\"\u003eFragrance\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA naturally occurring terpene found in citrus peel oils and many plants. Present in trace amounts as part of the formulation base. Provides a faint, clean citrus scent. Note: Classified as a fragrance ingredient by INCI standards.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant:\u003c\/strong\u003e Acts as a free radical scavenger in the formulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComedogenic Rating:\u003c\/strong\u003e 0\/5.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFungal Acne Status:\u003c\/strong\u003e Safe — terpene, not a fatty acid ester.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eWhen exposed to air, oxidized limonene can become a skin sensitizer. Individuals with fragrance sensitivity or reactive\/rosacea-prone skin should perform a patch test. This product is NOT 100% fragrance-free due to limonene content.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-accordion\"\u003e\n\u003cinput type=\"checkbox\" id=\"pp-inci\"\u003e\n\u003clabel for=\"pp-inci\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Full Ingredients (INCI)\u003c\/label\u003e\n\u003cdiv class=\"pp-acc-content\"\u003e\n\u003cp\u003e\u003cstrong\u003e9 ingredients total\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp style=\"font-size:0.85em;color:#64748b;line-height:1.8;\"\u003eBenzoyl Peroxide (5%), Clindamycin Phosphate (1%), Carbon, Diheptyl Sodium Sulfosuccinate, Limonene, Phosphoric Acid, Propylene Glycol, Sodium Hydroxide, Water\u003c\/p\u003e\n\u003cdiv class=\"free-list\"\u003e\n\u003cstrong\u003eFREE FROM:\u003c\/strong\u003e Parabens · Retinoids · Salicylic Acid · Sulfates · Silicones · Artificial Dyes · Essential Oils · Gluten · Alcohol · Hydroquinone\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-routine\"\u003e\n\u003cspan class=\"eyebrow\"\u003e04\u003c\/span\u003e\u003ch2\u003eWhere it fits in your routine\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eROUTINE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-routine\"\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eGentle Cleanser\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003ePat Dry\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step current\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eThis Gel (Rx Treatment)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eNon-Comedogenic Moisturizer\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eSPF 30+ Sunscreen (AM only)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e6\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eMakeup (1 hr after, optional)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cp style=\"text-align:center;color:var(--pp-text-muted);font-size:0.82em;margin-top:12px\"\u003eApply to the entire face — not just individual pimples — twice daily (morning and evening) unless directed otherwise. Wait 15 minutes after cleansing before applying. Do not layer with other topical acne actives (AHA, BHA, retinoids) without physician guidance.\u003c\/p\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-how-to-use\"\u003e\n\u003cspan class=\"eyebrow\"\u003e05\u003c\/span\u003e\u003ch2\u003eHow to use\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eHOW TO USE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-steps\"\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eCleanse Gently\u003c\/h4\u003e\n\u003cp\u003eWash your face with a mild, non-medicated cleanser using only your hands — avoid abrasive scrubs or exfoliating cleansers. Rinse thoroughly with warm water and pat dry.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eWait 15 Minutes\u003c\/h4\u003e\n\u003cp\u003eAllow skin to fully dry before applying the gel. Applying to damp skin can increase irritation and erythema, especially during the initial weeks of treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eApply a Thin Layer\u003c\/h4\u003e\n\u003cp\u003eDispense a small pea-sized amount and spread a thin, even layer over the entire affected area. Avoid the eyes, lips, nostrils, and any mucous membranes or broken skin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eAllow to Absorb\u003c\/h4\u003e\n\u003cp\u003eLet the gel absorb fully — approximately 30 seconds. Do not rinse off. Resist the urge to apply more product to stubborn areas; excess application increases dryness without added benefit.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eFollow with Moisturizer\u003c\/h4\u003e\n\u003cp\u003eApply a non-comedogenic, oil-free moisturizer to minimize dryness and peeling. Products such as Cetaphil, CeraVe, or La Roche-Posay Toleriane are commonly recommended by dermatologists with this medication.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e6\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eApply SPF in the Morning\u003c\/h4\u003e\n\u003cp\u003eBenzoyl Peroxide increases photosensitivity. Apply a broad-spectrum SPF 30 or higher sunscreen every morning as the final step. Reapply every 2 hours if outdoors. Non-medicated makeup may be applied 1 hour after the gel.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-who-is-it-for\"\u003e\n\u003cspan class=\"eyebrow\"\u003e06\u003c\/span\u003e\u003ch2\u003eWho is it for?\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eWHO\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-fit\"\u003e\n\u003cdiv class=\"pp-fit-box yes\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003ePerfect for you if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have mild to moderately severe inflammatory acne vulgaris (papules, pustules)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e OTC benzoyl peroxide or salicylic acid products have not produced adequate results\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You want a single-product dual-action treatment prescribed by a dermatologist\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Your skin is oily or combination and prone to frequent breakouts\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are 12 years of age or older\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You want to minimize antibiotic resistance risk vs. clindamycin monotherapy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fit-box no\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003eConsider alternatives if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are pregnant or breastfeeding without explicit physician approval\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have a history of colitis, ulcerative colitis, or antibiotic-associated diarrhea\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have severe cystic or nodulocystic acne (may require isotretinoin or oral antibiotics)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have known hypersensitivity to clindamycin, lincomycin, or benzoyl peroxide\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have rosacea or severely reactive skin prone to extreme sensitization\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You need a fully fragrance-free formula (contains limonene)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-skin-types\"\u003e\n\u003cspan class=\"eyebrow\"\u003e07\u003c\/span\u003e\u003ch2\u003eSkin type compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSKIN TYPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-skin-grid\"\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eOily Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eIdeal match. The oil-free aqueous gel formula absorbs quickly without adding shine, while BPO helps reduce excess sebum production and keeps pores clear.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eAcne-Prone Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eThis is the primary target skin type. Non-comedogenic, targets bacteria and inflammation simultaneously, and helps prevent new breakouts while treating existing ones.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eCombination Skin\u003c\/div\u003e\n\u003cspan class=\"rate good\"\u003eGood\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eWorks well on T-zone acne while remaining light enough for drier facial zones. Pair with a good moisturizer to keep cheeks and jaw hydrated.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eNormal Skin\u003c\/div\u003e\n\u003cspan class=\"rate good\"\u003eGood\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eEffective when breakouts are the primary concern. Moisturizer is still recommended to counterbalance BPO's drying effect even on normal skin types.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eDry Skin\u003c\/div\u003e\n\u003cspan class=\"rate moderate\"\u003eModerate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eCan be used but requires diligent moisturization. BPO and clindamycin may exacerbate dryness, flaking, and tightness. Start with once-daily application and build tolerance gradually.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eSensitive \/ Reactive Skin\u003c\/div\u003e\n\u003cspan class=\"rate moderate\"\u003eModerate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eRequires extra caution. Initial redness, burning, and flaking are common. Use every other day to start, and always apply a barrier-supporting moisturizer. Contains limonene — patch test advised for fragrance-sensitive individuals.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-results\"\u003e\n\u003cspan class=\"eyebrow\"\u003e08\u003c\/span\u003e\u003ch2\u003eResults timeline\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eWEEKS 8–12\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-timeline\"\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eDays 1–7\u003c\/span\u003e\n\u003ch4\u003eAdjustment Phase — Initial Irritation Possible\u003c\/h4\u003e\n\u003cp\u003eMost users experience some dryness, mild redness, and occasionally a brief purging phase as BPO accelerates skin cell turnover. This is normal and expected. Begin with once-daily use if irritation is significant.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~70% notice initial dryness\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeeks 2–4\u003c\/span\u003e\n\u003ch4\u003eEarly Antibacterial Effect — Fewer New Pimples\u003c\/h4\u003e\n\u003cp\u003eClindamycin begins suppressing C. acnes bacterial load. New inflammatory lesions start appearing less frequently. Some users report visible clearing of surface-level pustules within the first 2 weeks.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~45% report early improvement\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeeks 4–8\u003c\/span\u003e\n\u003ch4\u003eVisible Lesion Reduction — Fewer Papules and Pustules\u003c\/h4\u003e\n\u003cp\u003eClinical studies show statistically significant reductions in both inflammatory and noninflammatory lesion counts by week 4–6. Skin texture begins to improve. Redness from healing lesions starts to fade.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~60% see notable clearing\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeeks 8–12\u003c\/span\u003e\n\u003ch4\u003ePeak Efficacy — Sustained Clearance\u003c\/h4\u003e\n\u003cp\u003eThe 10-week endpoint used in pivotal clinical trials. Users see maximum reduction in total lesion count and global improvement. Physician-rated global improvement scores are significantly greater than benzoyl peroxide or clindamycin monotherapy.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~69% report positive outcomes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-reviews\"\u003e\n\u003cspan class=\"eyebrow\"\u003e09\u003c\/span\u003e\u003ch2\u003eRatings by platform\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e1K+ REVIEWS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-reviews\"\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eDrugs.com\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 7.7\/10\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e576+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Initial dryness and skin irritation during the first weeks of use\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eWebMD\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.0\/5\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e100+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Excessive dryness and burning sensation in the first 1–2 weeks\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-cart\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eAmazon (Generic Rx)\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.3\/5\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e500+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Prescription requirement and high out-of-pocket cost without insurance\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003ePubMed Clinical Trials\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e Proven\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eEvidence\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e758\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eTrial Patients\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Noted limitation: Not evaluated beyond 12 weeks; no data for noninflammatory acne\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-pros-cons\"\u003e\n\u003cspan class=\"eyebrow\"\u003e10\u003c\/span\u003e\u003ch2\u003ePros \u0026amp; cons\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eBALANCED\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-proscons\"\u003e\n\u003cdiv class=\"pp-pc pros\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003ePraised\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e FDA-approved with two robust clinical trials\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Dual-action formula outperforms either ingredient alone\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e BPO actively reduces antibiotic resistance — a major long-term benefit\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fast-absorbing, non-greasy oil-free gel texture\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Works on both inflammatory papules and noninflammatory comedones\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Can be worn under makeup (applied 1 hour before)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Affordable generic price vs. brand-name equivalents\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Highly rated by dermatologists as a first-line combo therapy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-pc cons\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eCriticized\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Requires a prescription — not available OTC\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Bleaches fabric, pillowcases, and towels\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Short 3-month PAO after dispensing; may be wasted if used infrequently\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Initial purging and dryness can be significant\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Contains limonene — not 100% fragrance-free\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Increased photosensitivity requires strict daily SPF use\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Not evaluated for use beyond 12 weeks\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Contraindicated for patients with a history of colitis\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-dupes\"\u003e\n\u003cspan class=\"eyebrow\"\u003e11\u003c\/span\u003e\u003ch2\u003eBudget-friendly alternatives (dupes)\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eDUPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-dupes\"\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match high\"\u003e95% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"photo-fallback\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003eNeuac Gel (Generic Clindamycin 1% \/ BPO 5%)\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003eSimilar Rx Price\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eSame Formula\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eAnother FDA-approved generic version of the same 1%\/5% combination. Virtually identical active ingredient profile. May differ slightly in inactive excipients. Check with your pharmacist for the best-priced generic at your pharmacy.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e72% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/acne-gel-wash\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/p5bidmi9mc9y4ok3ql0l3x47aabk.jpg?v=1773811791\" alt=\"Acne Gel Wash\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/acne-gel-wash\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003ePanOxyl Acne Foaming Wash 10% + Clindamycin 1% Gel (Separate Rx)\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003ePotentially Lower Rx Cost\u003c\/div\u003e\n\u003cdiv class=\"tag similar\"\u003eDIY Combo\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eUsing a separate topical clindamycin 1% gel alongside an OTC BPO wash or cream can replicate the therapeutic rationale. However, requires two products, careful sequencing, and is less convenient. BPO wash may be less effective than leave-on BPO gel at the same concentration.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e65% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"photo-fallback\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003eDifferin Gel (Adapalene 0.1%) + OTC BPO 2.5%\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e~$15–$25 OTC\u003c\/div\u003e\n\u003cdiv class=\"tag similar\"\u003eNo Rx Needed\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eA fully OTC alternative combining adapalene (retinoid) with benzoyl peroxide. No antibiotic resistance concerns. Different mechanism — retinoids normalize cell turnover rather than killing bacteria directly. Less effective for purely inflammatory acne but excellent for comedonal and mixed acne. No bleaching risk from adapalene.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-compare\"\u003e\n\u003cspan class=\"eyebrow\"\u003e12\u003c\/span\u003e\u003ch2\u003eComparison with competitors\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSIDE-BY-SIDE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-compare\"\u003e\n\u003cdiv class=\"pp-compare-card featured\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003ePerrigo Clindamycin\/BPO Gel 1%\/5%\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eClindamycin Concentration\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003e1%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eBenzoyl Peroxide Concentration\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003e5%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eApplication Frequency\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eTwice Daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Resistance Reduction\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes (BPO 5%)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFDA Approved\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eSize\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e50g\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePAO After Dispensing\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e3 Months\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePrescription Required\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003eBenzaClin Gel (Valeant \/ Bausch) — Brand Name\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eClindamycin Concentration\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e1%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eBenzoyl Peroxide Concentration\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e5%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eApplication Frequency\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eTwice Daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Resistance Reduction\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes (BPO 5%)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePAO After Dispensing\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e3 Months\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eCost vs. Perrigo Generic\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eSignificantly Higher\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eClinical Differentiation\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eSame Formula\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003eAcanya Gel — Clindamycin 1.2% \/ BPO 2.5%\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eClindamycin Concentration\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e1.2%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eBenzoyl Peroxide Concentration\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003e2.5% (Lower)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eApplication Frequency\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eOnce Daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eIrritation Potential\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eLower (2.5% BPO)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePAO After Dispensing\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e10 Weeks\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFabric Bleaching Risk\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eLower\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eBest For\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eSensitive Acne-Prone\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003eEpiduo Forte — Adapalene 0.3% \/ BPO 2.5%\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eMechanism\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eRetinoid + Antibacterial\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Component\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNone (No Antibiotic)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Resistance Risk\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eZero\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eComedonal Acne Efficacy\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFabric Bleaching\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eLow (2.5% BPO)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePregnancy Safe\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo (Retinoid)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eBest For\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eMixed \/ Comedonal Acne\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-storage\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eStorage \u0026amp; shelf life\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e3 MONTHS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePeriod After Opening (PAO)\u003c\/strong\u003e\n\u003cp\u003e3 months (approximately 90 days) after dispensing. This applies to BenzaClin-equivalent formulations. After this period, the stability of the active ingredients may be compromised. Check the expiration date provided by your pharmacy.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eStorage Instructions\u003c\/strong\u003e\n\u003cp\u003eStore at room temperature between 68°F–77°F (20°C–25°C). Store in a cool, dry place away from moisture and heat. Do not freeze. Keep jar or tube tightly closed when not in use. Keep upright if using a pump dispenser.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePackaging Type\u003c\/strong\u003e\n\u003cp\u003eAvailable as a 50g glass or plastic jar, or with a pump dispenser depending on manufacturer. The Perrigo version is typically dispensed in a 50g jar. Some versions may come as a kit requiring pharmacist mixing before dispensing.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-package\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTravel Friendly\u003c\/strong\u003e\n\u003cp\u003eYes — 50g (approximately 1.76 oz) is under the 100ml TSA carry-on liquid limit. Keep in original packaging with pharmacy label for identification. Prescription medications are generally allowed in carry-on baggage with proper documentation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-faq\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eFAQ\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq1\"\u003e\n\u003clabel for=\"faq1\"\u003eIs Clindamycin and Benzoyl Peroxide Gel 1%\/5% pregnancy and breastfeeding safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eThis product should only be used during pregnancy under the explicit guidance of a physician or OB-GYN. Clindamycin Phosphate is FDA Pregnancy Category B — animal studies have not demonstrated fetal risk, but there are no adequate, well-controlled studies in pregnant women. Benzoyl Peroxide has very low systemic absorption (\u0026lt;2%), but safety in pregnancy has not been formally established. During breastfeeding, avoid applying the gel to the chest or breast area to prevent any possibility of infant ingestion. The safest approach is to consult your dermatologist and OB-GYN before starting or continuing this medication during pregnancy or lactation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq2\"\u003e\n\u003clabel for=\"faq2\"\u003eIs Clindamycin and Benzoyl Peroxide Gel 1%\/5% fungal acne (malassezia) safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eYes, this formula is generally considered safe for those prone to fungal acne (Malassezia folliculitis). The ingredient list contains no fatty acids in the C11–C24 range that Malassezia feeds on. The diheptyl sodium sulfosuccinate present in the Perrigo formula uses short C7 heptyl chains that fall below the carbon chain length required to feed Malassezia. Additionally, Benzoyl Peroxide itself has well-documented antifungal activity and has been used as a treatment for Malassezia-related conditions. If you are uncertain, consult your dermatologist who prescribed this medication.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq3\"\u003e\n\u003clabel for=\"faq3\"\u003eCan I use Clindamycin and Benzoyl Peroxide Gel with retinol, vitamin C, AHA, or BHA?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eProceed with caution and physician guidance before layering this medication with other topical actives. Combining with AHA (glycolic\/lactic acid), BHA (salicylic acid), or retinoids (retinol, tretinoin, adapalene) significantly increases the risk of skin irritation, excessive dryness, peeling, and barrier damage — especially in the first weeks of treatment. Many dermatologists recommend starting with this gel alone, building skin tolerance over 4–6 weeks, and then carefully introducing other actives if needed. Vitamin C (ascorbic acid) is generally lower-risk but should still be used at a separate time of day. Do not use with erythromycin-containing products — they may counteract the antibacterial activity of clindamycin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq4\"\u003e\n\u003clabel for=\"faq4\"\u003eWhat skin type is Clindamycin and Benzoyl Peroxide Gel 1%\/5% best for?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eThis prescription gel is best suited for oily and acne-prone skin types dealing with mild to moderately severe inflammatory acne vulgaris (papules, pustules). It performs excellently on oily skin because the oil-free aqueous gel texture absorbs quickly without adding shine. Combination skin also responds very well. Dry and sensitive skin types can use it, but they require more diligent moisturization and a gradual build-up in frequency (starting every other day) to prevent excessive dryness and irritation. It is not recommended as a first-choice option for purely non-inflammatory or comedonal-only acne — adapalene-based products may be more effective in those cases.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq5\"\u003e\n\u003clabel for=\"faq5\"\u003eHow long until I see results from Clindamycin and Benzoyl Peroxide Gel 1%\/5%?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eResults vary by individual, but here is a general timeline based on clinical data and patient experience: Days 1–14: Adjustment phase — possible initial dryness, redness, or minor purging as skin adapts to BPO. Some users see early improvement in surface pustules within the first week. Weeks 2–4: Reduction in the frequency of new breakouts as clindamycin suppresses bacterial load. Weeks 4–8: Visible reduction in inflammatory lesions; skin texture begins to improve. Weeks 8–12: Peak efficacy per clinical trials — up to 69% of patients report a positive outcome by week 10. Do not discontinue early due to initial irritation; the most meaningful results come after sustained use. Consult your dermatologist if you see no improvement after 8 weeks.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq6\"\u003e\n\u003clabel for=\"faq6\"\u003eWhere does Clindamycin and Benzoyl Peroxide Gel go in my skincare routine?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eApply this gel as your first treatment step after cleansing and fully drying your skin. The correct routine order is: (1) Gentle non-medicated cleanser → (2) Pat dry, wait 15 minutes → (3) Apply this gel to the entire face in a thin layer → (4) Let absorb for 30 seconds → (5) Non-comedogenic moisturizer → (6) SPF 30+ sunscreen in the morning. Non-medicated makeup may be applied approximately 1 hour after the gel. Do not layer other topical acne medications unless directed by your physician. This gel is applied twice daily — morning and evening — for the 1%\/5% formulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq7\"\u003e\n\u003clabel for=\"faq7\"\u003eIs Clindamycin and Benzoyl Peroxide Gel comedogenic — will it clog pores?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eNo — this formulation has a comedogenic rating of 0\/5. It is an oil-free aqueous gel with no comedogenic oils, waxes, or heavy silicones. The active ingredients (clindamycin and benzoyl peroxide) actually work to unclog pores by reducing bacterial populations and promoting gentle desquamation (skin cell shedding). The inactive ingredients — propylene glycol, carbon, diheptyl sodium sulfosuccinate, and water — are all non-comedogenic. This product was specifically designed for acne-prone skin and is a standard dermatologist prescription precisely because it does not aggravate existing blockages.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq8\"\u003e\n\u003clabel for=\"faq8\"\u003eHow long does Clindamycin and Benzoyl Peroxide Gel 1%\/5% last after opening?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eThis gel has a Period After Opening (PAO) of approximately 3 months (90 days) after dispensing by the pharmacy. After this point, the stability and potency of the active ingredients — particularly benzoyl peroxide, which can degrade over time — may be compromised. The 50g jar used twice daily on the face should be largely consumed within this window for typical adult acne treatment. Always check the expiration date label your pharmacist provides. Store at room temperature (68–77°F \/ 20–25°C), away from moisture and heat, and do not freeze. Discard any unused product after the expiration date.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-verdict\"\u003e\n    \u003cdiv class=\"eyebrow\"\u003e— Skincarisma verdict\u003c\/div\u003e\n    \u003cdiv class=\"score-row\"\u003e\n      \u003cspan class=\"score\"\u003e4.5\u003c\/span\u003e\n      \u003cspan class=\"max\"\u003e\/ 5\u003c\/span\u003e\n      \u003cspan class=\"stars\"\u003e★★★★★\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"text\"\u003e\n\u003cstrong\u003eVerdict:\u003c\/strong\u003e Perrigo's Clindamycin and Benzoyl Peroxide Gel 1%\/5% is a gold-standard prescription acne treatment backed by robust clinical evidence and decades of dermatological use. Its dual-mechanism formula — combining an antibiotic that inhibits bacterial protein synthesis with an oxidizing antibacterial that generates zero antibiotic resistance — makes it more effective than either ingredient used alone, as demonstrated in controlled trials of 758 patients. The lightweight, oil-free gel texture is ideal for oily and acne-prone skin, absorbing quickly without shine. The key trade-off: it requires a prescription, bleaches fabrics, has a short 3-month PAO, and the initial 2–4 weeks can involve dryness and irritation that demands commitment. For anyone with moderate inflammatory acne who has not responded adequately to OTC treatments, this remains one of the most clinically justified options available. Pair it with a non-comedogenic moisturizer and daily SPF for best results.\n\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003cbutton class=\"pp-back-to-top\" aria-label=\"Back to top\" type=\"button\" style=\"position:fixed;bottom:24px;right:24px;width:44px;height:44px;border-radius:50%;background:var(--pp-accent);color:#fff;border:none;display:none;cursor:pointer;z-index:50;box-shadow:0 4px 16px rgba(13,31,45,0.2)\"\u003e↑\u003c\/button\u003e\n  \u003cscript\u003e\n  (function () {\n    var btt = document.querySelector('.pp-back-to-top');\n    if (!btt) return;\n    var ticking = false;\n    function onScroll () {\n      if (!ticking) {\n        requestAnimationFrame(function () {\n          btt.style.display = window.scrollY \u003e 600 ? 'block' : 'none';\n          ticking = false;\n        });\n        ticking = true;\n      }\n    }\n    window.addEventListener('scroll', onScroll, { passive: true });\n    btt.addEventListener('click', function () { window.scrollTo({ top: 0, behavior: 'smooth' }); });\n  })();\n  \u003c\/script\u003e\n\u003c\/div\u003e\n","brand":"Perrigo","offers":[{"title":"Default Title","offer_id":52117440790871,"sku":null,"price":12990.01,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/492v7xrd29s99wit964b0er1n5ra.jpg?v=1767016710","url":"https:\/\/www.skincarisma.com\/products\/clindamycin-and-benzoyl-peroxide-gel-1-5","provider":"Skincarisma","version":"1.0","type":"link"}