{"product_id":"clindamycin-phosphate-topical-solution","title":"Clindamycin Phosphate Topical Solution","description":"\u003cdiv class=\"pp\" lang=\"en\" itemscope itemtype=\"https:\/\/schema.org\/Product\"\u003e\n  \u003cmeta itemprop=\"name\" content=\"Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution\"\u003e\n  \u003cmeta itemprop=\"brand\" content=\"Glasshouse Pharmaceuticals\"\u003e\n  \u003cmeta itemprop=\"category\" content=\"Skincare \u0026gt; Prescription\"\u003e\n  \u003cmeta itemprop=\"countryOfOrigin\" content=\"Various\"\u003e\n\n  \u003cscript type=\"application\/ld+json\"\u003e{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"FAQPage\",\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Clindamycin Phosphate Topical Solution pregnancy and breastfeeding safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Use with caution during pregnancy — only if clearly prescribed and deemed necessary by your healthcare provider. Systemic clindamycin administered during the second and third trimesters has not been associated with an increased frequency of congenital abnormalities in clinical trials. However, topical application can result in some systemic absorption through the skin. It is not known with certainty whether topically absorbed clindamycin passes into breast milk in significant amounts, though oral forms are known to do so. Always consult your OB-GYN or midwife before using any prescription topical antibiotic during pregnancy or while breastfeeding.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Clindamycin Phosphate Topical Solution fungal acne (malassezia) safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Yes — this is one of the most fungal-acne-safe prescription acne treatments available. The Glasshouse Pharmaceuticals formulation contains only 5 ingredients: isopropyl alcohol, water, propylene glycol, clindamycin phosphate, and sodium hydroxide. None of these ingredients are fatty acids, fermented ingredients, esters, or polysorbates that feed Malassezia yeast. Clindamycin itself is an antibacterial antibiotic — it does not disrupt or worsen fungal conditions. If you suffer from pityrosporum folliculitis (fungal acne) alongside bacterial acne, this topical solution is a safe prescription option to discuss with your dermatologist.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can I use Clindamycin Phosphate Topical Solution with retinol, vitamin C, AHAs, or BHAs?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Clindamycin 1% solution can be combined with retinoids (tretinoin, adapalene, retinol) — in fact, this is a frequently prescribed combination as retinoids address comedonal acne while clindamycin targets inflammatory lesions. Apply them at different times (e.g., clindamycin in the morning, retinoid at night) to minimize irritation. Combining clindamycin with vitamin C (ascorbic acid) is generally fine, as they address different concerns. With AHAs and BHAs: layering multiple actives increases irritation risk given the already high alcohol content. If using chemical exfoliants, apply them at a separate time and start slowly. Benzoyl peroxide (BPO) is the most recommended combination partner — always apply BPO and clindamycin at different times of day to prevent potential inactivation and to protect against antibiotic resistance.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What skin type is Clindamycin Phosphate Topical Solution best for?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"This solution is best suited for oily, acne-prone, and combination skin types with inflammatory acne (red, swollen pimples). The alcohol-based, oil-free formulation is ideal for oily skin — it absorbs instantly, leaves a matte finish, and does not add grease or clog pores (comedogenic rating: 0\/5). It is also excellent for those prone to fungal acne alongside bacterial acne. It is less ideal for dry skin or sensitive skin types due to the high 50% isopropyl alcohol content, which can cause dryness, tightness, and stinging. Dry-skinned users should follow immediately with a rich, non-comedogenic moisturizer and may wish to use it once daily rather than twice until tolerance builds.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long until I see results from Clindamycin Phosphate Topical Solution?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Most users notice initial improvement — particularly in redness and swelling of existing pimples — within the first 1–2 weeks. Meaningful reduction in the number of breakouts typically becomes evident between weeks 4 and 6 with consistent twice-daily application. Full therapeutic benefit is generally assessed at 8–12 weeks, which is the clinical standard for evaluating topical antibiotic efficacy. According to Mayo Clinic guidance and clinical literature, if no improvement is seen after 6 weeks, or if acne worsens, consult your dermatologist to reassess your treatment plan. Consistency is critical — missing applications significantly reduces efficacy.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Where does Clindamycin Phosphate Topical Solution go in my skincare routine?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Apply Clindamycin Phosphate Topical Solution as Step 3 in your routine: after cleansing and toning, before serums and moisturizers. The correct order is: Cleanser → Toner (optional) → Clindamycin Solution → Wait 5–10 minutes for full drying → Serum → Moisturizer → Sunscreen (AM only). The solution should always be applied to clean, dry skin. Do not apply other products on top until the solution is fully dry. If you use benzoyl peroxide, apply it at a completely different time of day (e.g., clindamycin in the PM, BPO in the AM) to avoid potential interaction and to reduce antibiotic resistance development.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Clindamycin Phosphate Topical Solution comedogenic \/ will it clog pores?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No — this product is non-comedogenic and rates 0\/5 on the comedogenic scale. None of its 5 ingredients (isopropyl alcohol, water, propylene glycol, clindamycin phosphate, sodium hydroxide) are known to clog pores. The formula contains no oils, waxes, fatty acids, silicones, or any other ingredients associated with pore blockage. In fact, the 50% isopropyl alcohol base is well-known for its de-greasing, pore-clarifying properties. This makes the solution an appropriate choice for acne-prone skin where pore-clogging is a significant concern.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long does Clindamycin Phosphate Topical Solution last after opening?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"The Period After Opening (PAO) for Clindamycin Phosphate Topical Solution USP 1% is 12 months. Store at controlled room temperature of 20–25°C (68–77°F) and protect from freezing. Always keep the applicator cap tightly closed when not in use to prevent evaporation of the isopropyl alcohol vehicle and potential concentration changes or contamination. The 30 mL bottle provides approximately a 1-month supply when used twice daily as directed, so the full bottle will typically be used well within its PAO window. The 60 mL bottle provides approximately a 2-month supply. Discard if the solution changes color, develops unusual particles, or smells different from normal.\"\n          }\n        }\n      ]\n    },\n    {\n      \"@type\": \"HowTo\",\n      \"name\": \"How to use Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution\",\n      \"totalTime\": \"PT2M\",\n      \"step\": [\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 1,\n          \"name\": \"Cleanse \u0026amp; Dry Thoroughly\",\n          \"text\": \"Wash your face with a mild, non-irritating cleanser and pat completely dry. Ensure skin is fully dry before applying — avoid applying immediately after washing or shaving as the alcohol base can cause significant stinging on wet or freshly shaved skin. Wait at least 30 minutes post-shave.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 2,\n          \"name\": \"Apply a Thin Film to Affected Areas\",\n          \"text\": \"Dispense a small amount of the solution and apply a thin, even film to the entire affected acne-prone area — not just individual spots. If using the applicator tip, use a gentle dabbing motion rather than rolling to avoid dragging the liquid. Apply to the whole zone (e.g., entire face if treating facial acne) for best results.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 3,\n          \"name\": \"Allow to Dry Fully (2–5 Minutes)\",\n          \"text\": \"The high alcohol content means the solution evaporates quickly. Wait until the treated area is completely dry (no tacky feeling) before applying any other skincare product. This prevents dilution of the active ingredient and ensures optimal absorption.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 4,\n          \"name\": \"Apply Moisturizer to Combat Dryness\",\n          \"text\": \"The 50% isopropyl alcohol content can cause dryness and tightness. Always follow with a non-comedogenic, oil-free moisturizer to maintain the skin barrier. Choose a lightweight gel moisturizer for oily skin, or a gentle cream for dry\/combination skin types.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 5,\n          \"name\": \"Use Twice Daily (AM \u0026amp; PM) as Directed\",\n          \"text\": \"Standard prescribing is twice daily — once in the morning and once at night. To minimize antibiotic resistance, apply benzoyl peroxide at a different time of day from clindamycin. Follow your dermatologist's specific instructions regarding frequency and duration of use.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 6,\n          \"name\": \"Continue for the Full Duration Prescribed\",\n          \"text\": \"Improvement typically begins at 4–8 weeks, with full results at 8–12 weeks. Do not stop early even if skin looks clearer — stopping prematurely allows resistant bacteria to repopulate. Use only for the duration prescribed by your healthcare provider.\"\n        }\n      ]\n    },\n    {\n      \"@type\": \"ItemList\",\n      \"name\": \"Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution — Ingredients (INCI)\",\n      \"numberOfItems\": 5,\n      \"itemListElement\": [\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 1,\n          \"name\": \"Isopropyl Alcohol (50% v\/v)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 2,\n          \"name\": \"Water (Aqua)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 3,\n          \"name\": \"Propylene Glycol\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 4,\n          \"name\": \"Clindamycin Phosphate (1% \/ 10 mg\/mL)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 5,\n          \"name\": \"Sodium Hydroxide\"\n        }\n      ]\n    }\n  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y2=\"7\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-home\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M3 11l9-7 9 7v9a2 2 0 01-2 2h-4v-7H9v7H5a2 2 0 01-2-2v-9z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-plane\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M22 12l-9 4-3 6-2-5-5-2 6-3 4-9 9 9z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-arrow-right\" viewbox=\"0 0 24 24\"\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003cpolyline points=\"12 5 19 12 12 19\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n    \u003c\/defs\u003e\n  \u003c\/svg\u003e\n\n  \n  \u003csection id=\"pp-overview\" class=\"pp-hero\" aria-labelledby=\"pp-hero-title\"\u003e\n    \u003ch2 id=\"pp-hero-title\" class=\"pp-sr-only\" style=\"position:absolute;left:-10000px\"\u003eProduct overview\u003c\/h2\u003e\n    \u003cdiv class=\"pp-origin\"\u003e\n      \u003csvg class=\"pin\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-pin\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n      \u003cspan class=\"text\"\u003eMade in Various\u003c\/span\u003e\n      \u003cspan class=\"dot\"\u003e\u003c\/span\u003e\n      \u003cspan class=\"tag\"\u003eINTERNATIONAL\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"pp-subtitle\"\u003eA prescription-strength topical antibiotic solution containing 1% Clindamycin Phosphate — clinically proven to fight acne-causing bacteria (C. acnes), reduce inflammation, and clear active breakouts. With only 5 clean pharmaceutical-grade ingredients, this oil-free, fragrance-free, and fungal-acne-safe solution is one of the most minimal and effective topical antibiotics available for mild-to-moderate acne vulgaris.\u003c\/p\u003e\n    \u003cdiv class=\"pp-badges\"\u003e\n\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Prescription Strength\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fungal Acne Safe\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fragrance-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Oil-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Paraben-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Silicone-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Non-Comedogenic (0\/5)\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Sulfate-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Only 5 Ingredients\u003c\/span\u003e\n\u003c\/div\u003e\n    \u003cnav class=\"pp-nav\" aria-label=\"Jump to product section\"\u003e\n      \u003cdiv class=\"pp-nav-head\"\u003eJump to section\u003c\/div\u003e\n      \u003cdiv class=\"pp-nav-list\"\u003e\n        \u003ca href=\"#pp-safety\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSafety\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-ingredients\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eIngredients\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-routine\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-refresh\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eRoutine\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-how-to-use\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eHow to use\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-skin-types\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSkin types\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-results\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-trending\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eResults\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-reviews\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-star\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eReviews\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-dupes\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-coin\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eDupes\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-faq\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-help\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eFAQ\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/nav\u003e\n    \n    \u003cdiv class=\"pp-scorecard\"\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003ePregnancy\u003c\/div\u003e\n\u003cdiv class=\"val caution\"\u003e\n\u003csvg class=\"alert\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Caution\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eFungal Acne\u003c\/div\u003e\n\u003cdiv class=\"val safe\"\u003e\n\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Yes\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eComedogenic\u003c\/div\u003e\n\u003cdiv class=\"val safe\"\u003e0\/5\u003c\/div\u003e\n\u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pp-specs\"\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eType\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eRx Antibiotic\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eActive %\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e1% (10 mg\/mL)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eSize\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e30 mL \/ 60 mL\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003epH Range\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e4.0 – 7.0\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eIngredients\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e5 total\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n    \n    \n    \u003cdiv class=\"pp-highlight\"\u003e\n      \u003cspan class=\"eyebrow\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Why it's different\u003c\/span\u003e\n      \u003ch3\u003eKills Acne-Causing Bacteria\u003c\/h3\u003e\n      \u003cp\u003eClindamycin phosphate is bacteriostatic against Cutibacterium acnes (formerly P. acnes), the bacteria primarily responsible for inflammatory acne lesions.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n\n  \u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-sensory\"\u003e\n\u003cspan class=\"eyebrow\"\u003e01\u003c\/span\u003e\u003ch2\u003eTexture \u0026amp; feel\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSENSORY\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-sensory\"\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eConsistency\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eThin liquid solution\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-wind\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eScent\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eLight isopropyl alcohol\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eAbsorption\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eFast (\u0026lt;30 seconds)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eFinish\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eMatte \/ Dry\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-features\"\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eKills Acne-Causing Bacteria\u003c\/h4\u003e\n\u003cp\u003eClindamycin phosphate is bacteriostatic against Cutibacterium acnes (formerly P. acnes), the bacteria primarily responsible for inflammatory acne lesions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eReduces Redness \u0026amp; Inflammation\u003c\/h4\u003e\n\u003cp\u003eBeyond antibacterial action, topical clindamycin provides meaningful anti-inflammatory benefits, helping active pimples calm down faster and appear less red.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eMinimal, Pharmaceutical-Grade Formula\u003c\/h4\u003e\n\u003cp\u003eOnly 5 ingredients — no fillers, no fragrance, no oils, no comedogenic components. One of the cleanest topical antibiotic formulations available.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-leaf\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eFungal Acne (Malassezia) Safe\u003c\/h4\u003e\n\u003cp\u003eContains zero fatty acids, ferments, esters, or polysorbates. Completely safe for fungal acne-prone skin types who struggle with most conventional acne treatments.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eOil-Free \u0026amp; Non-Comedogenic\u003c\/h4\u003e\n\u003cp\u003eThe water-based and alcohol-based formulation contains no pore-clogging oils. Rates a perfect 0\/5 on the comedogenic scale — ideal for oily and acne-prone skin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eClinically Established \u0026amp; FDA-Approved\u003c\/h4\u003e\n\u003cp\u003eClindamycin 1% topical solution has decades of clinical data supporting its efficacy for acne vulgaris. A dermatologist first-line recommendation globally.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-safety\"\u003e\n\u003cspan class=\"eyebrow\"\u003e02\u003c\/span\u003e\u003ch2\u003eSafety \u0026amp; compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSAFE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePregnancy Safety\u003c\/strong\u003e\n\u003cp\u003eUse with caution during pregnancy — only if prescribed by a physician. Systemic clindamycin in the second and third trimesters has not shown increased congenital abnormalities, but topical absorption is possible. Always consult your OB-GYN before use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eBreastfeeding Safety\u003c\/strong\u003e\n\u003cp\u003eNot confirmed safe during breastfeeding. Oral clindamycin is known to pass into breast milk; it is unknown whether topical application results in significant milk transfer. Consult your doctor before use while nursing.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eFungal Acne (Malassezia) Safe\u003c\/strong\u003e\n\u003cp\u003e100% safe for fungal acne. The formula contains no fatty acids, fermented ingredients, esters, polysorbates, or Malassezia food sources. Appropriate for those who break out from many conventional acne products.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eNon-Comedogenic (0\/5)\u003c\/strong\u003e\n\u003cp\u003eRates zero on the comedogenic scale. No oils, waxes, or pore-clogging ingredients of any kind. Will not block pores or contribute to blackheads or comedonal acne.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eRetinoid-Free\u003c\/strong\u003e\n\u003cp\u003eDoes not contain any retinoids or retinol. Safe to layer with topical retinoids such as tretinoin or adapalene — in fact, combining with a retinoid is a common and effective dermatologist-recommended protocol.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSalicylic Acid \u0026amp; Hydroquinone Free\u003c\/strong\u003e\n\u003cp\u003eDoes not contain salicylic acid, AHAs, BHAs, or hydroquinone. No exfoliating acids in the formula, making it suitable for sensitive skin and safe to layer with separate acid-based treatments.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eAntibiotic Resistance Risk\u003c\/strong\u003e\n\u003cp\u003eLong-term use of topical antibiotics alone can contribute to antibiotic resistance in C. acnes. Dermatologists strongly recommend pairing with benzoyl peroxide (BPO) to prevent resistance development. Do not use indefinitely without physician oversight.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eContraindicated: GI History\u003c\/strong\u003e\n\u003cp\u003eContraindicated in people with a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis (including C. difficile). Even topical use can result in systemic absorption and rare GI side effects such as diarrhea or colitis.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eHigh Alcohol Content (50% IPA)\u003c\/strong\u003e\n\u003cp\u003eContains 50% isopropyl alcohol, which may cause dryness, irritation, or stinging, especially on broken skin, eczema, or rosacea-prone complexions. Start with once-daily use to assess tolerance before applying twice daily.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePrescription-Only (Rx)\u003c\/strong\u003e\n\u003cp\u003eThis is a prescription medication. Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution is not available over the counter. A valid prescription from a licensed healthcare provider is required for legal dispensing and use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-ingredients\"\u003e\n\u003cspan class=\"eyebrow\"\u003e03\u003c\/span\u003e\u003ch2\u003eIngredient breakdown\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eINGREDIENTS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eClindamycin Phosphate 1% (10 mg\/mL)\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eThe star active ingredient. Clindamycin phosphate is a water-soluble, semi-synthetic antibiotic derived from lincomycin. Although inactive in its phosphate form in vitro, it undergoes rapid enzymatic hydrolysis on skin to release free clindamycin — the antibacterially active compound. It works by binding to the 23S RNA of the bacterial 50S ribosomal subunit, thereby inhibiting protein synthesis and stopping C. acnes from reproducing.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism:\u003c\/strong\u003e Bacteriostatic — inhibits bacterial protein synthesis via 50S ribosomal binding\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e Cutibacterium acnes (formerly Propionibacterium acnes) — the primary acne-causing bacterium\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComedonal penetration:\u003c\/strong\u003e Mean antibiotic concentration in comedones after 4 weeks was 597 mcg\/g (range 0–1490 mcg\/g)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic absorption:\u003c\/strong\u003e Very low — serum levels of 0–3 ng\/mL after multiple topical applications; less than 0.2% recovered in urine\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical studies:\u003c\/strong\u003e Demonstrated efficacy across 18 clinical trials in various formulations against placebo and active comparators\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdditional benefit:\u003c\/strong\u003e Provides anti-inflammatory activity independent of direct antibacterial action\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eResistance risk: Always combine with benzoyl peroxide to minimize the development of clindamycin-resistant C. acnes strains. Do not use topical antibiotics as monotherapy indefinitely.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eIsopropyl Alcohol (IPA) 50% v\/v\u003cspan class=\"tag supporting\"\u003eVehicle\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eThe primary solvent and vehicle carrying clindamycin phosphate into the skin. At 50% concentration, IPA serves multiple roles: it dissolves the active ingredient, accelerates penetration through the stratum corneum, and provides rapid evaporation that leaves a dry, matte finish. IPA also imparts mild antimicrobial surface-cleansing properties.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRole:\u003c\/strong\u003e Primary solvent and penetration enhancer for clindamycin phosphate\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEvaporation:\u003c\/strong\u003e Rapid evaporation provides the signature quick-dry matte finish\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrawback:\u003c\/strong\u003e High alcohol content can disrupt the skin barrier and cause dryness or irritation with extended use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eMay cause stinging, dryness, or irritation — particularly on sensitive, eczema-prone, or recently shaved skin. Allow at least 30 minutes after washing or shaving before applying.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003ePropylene Glycol Low concentration\u003cspan class=\"tag supporting\"\u003eHumectant\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA small-molecule humectant that draws moisture into the skin and helps counterbalance the drying effects of isopropyl alcohol. Propylene glycol also acts as a co-solvent helping to keep the active ingredient dissolved and stable in solution. It extends the product's shelf life through mild antimicrobial properties and prevents the formulation from freezing or melting under temperature fluctuations.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRole:\u003c\/strong\u003e Humectant, co-solvent, and formulation stabilizer\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafety:\u003c\/strong\u003e Generally recognized as safe in cosmetic and pharmaceutical concentrations; rarely causes contact dermatitis in sensitive individuals\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBenefit:\u003c\/strong\u003e Partially offsets IPA-related dryness by retaining some skin moisture\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-callout positive\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eNon-comedogenic, non-allergenic in typical concentrations, and fungal-acne safe. One of the most well-tolerated pharmaceutical excipients.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003ePurified Water (Aqua) Excipient\u003cspan class=\"tag supporting\"\u003eVehicle\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eHigh-purity pharmaceutical-grade water serves as the aqueous vehicle of the formulation, providing the base in which all other ingredients are dissolved. Purified water ensures the pH stability and sterility required for a prescription pharmaceutical product.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRole:\u003c\/strong\u003e Aqueous solvent base for the solution\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrade:\u003c\/strong\u003e Pharmaceutical purified water — free from contaminants, minerals, and microorganisms\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFunction:\u003c\/strong\u003e Supports pH buffering and formulation homogeneity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eSodium Hydroxide pH adjuster\u003cspan class=\"tag supporting\"\u003eStabilizer\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eUsed in trace amounts to adjust and maintain the solution's pH between 4.0 and 7.0. This pH range is critical to ensure clindamycin phosphate remains chemically stable, microbiologically safe, and optimally bioavailable on the skin's surface. Without pH adjustment, the active ingredient could degrade or be less effective.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRole:\u003c\/strong\u003e pH adjuster to maintain the formulation at pH 4.0–7.0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafety:\u003c\/strong\u003e Used in trace (micro) amounts only — completely safe at these concentrations per FDA and global regulatory standards\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImportance:\u003c\/strong\u003e Ensures the stability and efficacy of clindamycin phosphate throughout shelf life\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-callout positive\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eThe tiny quantity of sodium hydroxide used is far below any irritation threshold. It is a standard and safe pharmaceutical excipient.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-accordion\"\u003e\n\u003cinput type=\"checkbox\" id=\"pp-inci\"\u003e\n\u003clabel for=\"pp-inci\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Full Ingredients (INCI)\u003c\/label\u003e\n\u003cdiv class=\"pp-acc-content\"\u003e\n\u003cp\u003e\u003cstrong\u003e5 ingredients\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIsopropyl Alcohol (50% v\/v), Water (Aqua), Propylene Glycol, Clindamycin Phosphate (1% \/ 10 mg\/mL), Sodium Hydroxide\u003c\/p\u003e\n\u003cdiv class=\"free-list\"\u003e\n\u003cstrong\u003eFREE FROM:\u003c\/strong\u003e Fragrance, Parabens, Silicones, Sulfates, Oils, Fatty Acids, Ferments, Esters, Polysorbates, Retinoids, Salicylic Acid, Hydroquinone, Dyes, Comedogenic Ingredients, Gluten, Vegan-friendly (no animal-derived ingredients)\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-routine\"\u003e\n\u003cspan class=\"eyebrow\"\u003e04\u003c\/span\u003e\u003ch2\u003eWhere it fits in your routine\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eROUTINE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-routine\"\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eCleanser\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eToner\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step current\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eThis Product\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eSerum \/ Treatment\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eMoisturizer\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e6\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eSunscreen (AM)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cp style=\"text-align:center;color:var(--pp-text-muted);font-size:0.82em;margin-top:12px\"\u003eApply to clean, dry skin before serums and moisturizers. Wait 5–10 minutes before the next step to allow the solution to fully dry. Apply benzoyl peroxide at a separate time of day (e.g., AM vs PM) to prevent interaction and reduce resistance risk.\u003c\/p\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-how-to-use\"\u003e\n\u003cspan class=\"eyebrow\"\u003e05\u003c\/span\u003e\u003ch2\u003eHow to use\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eHOW TO USE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-steps\"\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eCleanse \u0026amp; Dry Thoroughly\u003c\/h4\u003e\n\u003cp\u003eWash your face with a mild, non-irritating cleanser and pat completely dry. Ensure skin is fully dry before applying — avoid applying immediately after washing or shaving as the alcohol base can cause significant stinging on wet or freshly shaved skin. Wait at least 30 minutes post-shave.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eApply a Thin Film to Affected Areas\u003c\/h4\u003e\n\u003cp\u003eDispense a small amount of the solution and apply a thin, even film to the entire affected acne-prone area — not just individual spots. If using the applicator tip, use a gentle dabbing motion rather than rolling to avoid dragging the liquid. Apply to the whole zone (e.g., entire face if treating facial acne) for best results.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eAllow to Dry Fully (2–5 Minutes)\u003c\/h4\u003e\n\u003cp\u003eThe high alcohol content means the solution evaporates quickly. Wait until the treated area is completely dry (no tacky feeling) before applying any other skincare product. This prevents dilution of the active ingredient and ensures optimal absorption.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eApply Moisturizer to Combat Dryness\u003c\/h4\u003e\n\u003cp\u003eThe 50% isopropyl alcohol content can cause dryness and tightness. Always follow with a non-comedogenic, oil-free moisturizer to maintain the skin barrier. Choose a lightweight gel moisturizer for oily skin, or a gentle cream for dry\/combination skin types.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eUse Twice Daily (AM \u0026amp; PM) as Directed\u003c\/h4\u003e\n\u003cp\u003eStandard prescribing is twice daily — once in the morning and once at night. To minimize antibiotic resistance, apply benzoyl peroxide at a different time of day from clindamycin. Follow your dermatologist's specific instructions regarding frequency and duration of use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e6\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eContinue for the Full Duration Prescribed\u003c\/h4\u003e\n\u003cp\u003eImprovement typically begins at 4–8 weeks, with full results at 8–12 weeks. Do not stop early even if skin looks clearer — stopping prematurely allows resistant bacteria to repopulate. Use only for the duration prescribed by your healthcare provider.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-who-is-it-for\"\u003e\n\u003cspan class=\"eyebrow\"\u003e06\u003c\/span\u003e\u003ch2\u003eWho is it for?\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eWHO\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-fit\"\u003e\n\u003cdiv class=\"pp-fit-box yes\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003ePerfect for you if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have mild to moderate inflammatory acne (red, swollen pimples)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You've been prescribed this by a dermatologist or physician\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have oily or acne-prone skin and want a non-greasy, fast-drying treatment\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are prone to fungal acne (pityrosporum folliculitis) alongside bacterial acne\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You need an antibiotic treatment but want minimal, clean ingredients\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You want to pair a topical antibiotic with benzoyl peroxide or a retinoid for a comprehensive routine\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You prefer a matte finish with no residue or film\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fit-box no\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003eConsider alternatives if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have severe, nodulocystic acne (may require oral antibiotics or isotretinoin)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have only comedonal (non-inflammatory) acne — retinoids work better\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have extremely dry or eczema-prone skin sensitive to alcohol\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have a history of colitis, Crohn's disease, or antibiotic-associated GI issues\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are allergic to clindamycin or lincomycin\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are pregnant or breastfeeding (consult doctor first)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You do not have a prescription and cannot access one\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-skin-types\"\u003e\n\u003cspan class=\"eyebrow\"\u003e07\u003c\/span\u003e\u003ch2\u003eSkin type compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSKIN TYPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-skin-grid\"\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eOily Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eIdeal for oily skin types. The alcohol-based formulation absorbs almost instantly, leaves zero residue, and delivers a clean matte finish without adding any greasiness. Works synergistically with oil control routines.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eAcne-Prone Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eDesigned specifically for acne-prone skin. Kills C. acnes bacteria, reduces inflammation, and is non-comedogenic (0\/5). A dermatologist go-to for mild-to-moderate inflammatory breakouts.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eCombination Skin\u003c\/div\u003e\n\u003cspan class=\"rate good\"\u003eGood\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eWorks well on combination skin. The solution targets acne zones effectively while leaving non-oily areas alone. Follow with a lightweight moisturizer on drier areas to manage potential alcohol-related dryness.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eSensitive Skin\u003c\/div\u003e\n\u003cspan class=\"rate moderate\"\u003eModerate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eUse with caution. The 50% isopropyl alcohol can cause stinging, redness, and irritation in sensitive skin types. Patch test and start with once-daily application. Not recommended for rosacea-prone or eczema-prone skin without dermatologist guidance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eDry Skin\u003c\/div\u003e\n\u003cspan class=\"rate moderate\"\u003eModerate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eCan be used on dry skin with care. High alcohol content will exacerbate dryness and potential flaking. A rich, non-comedogenic moisturizer applied immediately after the solution dries is essential to maintain skin comfort and barrier integrity.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eFungal Acne-Prone\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eOne of very few prescription acne treatments that is completely fungal-acne safe. Contains none of the ingredients (fatty acids, esters, ferments, polysorbates) that feed Malassezia yeast, making it safe for those who break out from conventional acne treatments.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-results\"\u003e\n\u003cspan class=\"eyebrow\"\u003e08\u003c\/span\u003e\u003ch2\u003eResults timeline\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e3+ MONTHS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-timeline\"\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eDays 1–7\u003c\/span\u003e\n\u003ch4\u003eInitial Anti-Inflammatory Effect\u003c\/h4\u003e\n\u003cp\u003eMany users report visible reduction in redness and swelling of existing inflammatory lesions within the first few days. The antibacterial action begins immediately — clindamycin starts inhibiting C. acnes protein synthesis from the first application. Do not expect full clearance at this stage.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~45% noticed improvement\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeeks 2–4\u003c\/span\u003e\n\u003ch4\u003eReduction in Active Breakouts\u003c\/h4\u003e\n\u003cp\u003eNew inflammatory pimples begin to appear less frequently as bacterial load decreases. Existing lesions may heal faster. Some users may experience a mild adjustment period with initial increase in dryness or minor irritation before the skin adapts. Consistency is key at this stage.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~60% noticed improvement\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeeks 4–8\u003c\/span\u003e\n\u003ch4\u003eMeaningful Clearance\u003c\/h4\u003e\n\u003cp\u003eMost users see significant improvement in both the number of lesions and overall skin texture by week 6–8. The comedonal environment changes as C. acnes population is suppressed. Best results seen when paired with benzoyl peroxide or a retinoid as prescribed.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~68% reported positive experience\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeeks 8–12\u003c\/span\u003e\n\u003ch4\u003eFull Therapeutic Benefit\u003c\/h4\u003e\n\u003cp\u003eComplete assessment of efficacy should be made at 8–12 weeks. Clinical guidelines and dermatologists consider this the benchmark period for evaluating topical antibiotic response. If insufficient improvement is seen, your provider may adjust the treatment plan (add or switch agents).\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~75% achieved clear or mostly clear skin\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003e3+ Months\u003c\/span\u003e\n\u003ch4\u003eMaintenance \u0026amp; Resistance Management\u003c\/h4\u003e\n\u003cp\u003eLong-term use beyond 3 months without a resistance-prevention agent (BPO) increases resistance risk. Discuss with your dermatologist about transitioning to maintenance therapy — typically switching to a retinoid monotherapy or BPO maintenance after achieving clearance.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003eBest results with paired BPO therapy\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-reviews\"\u003e\n\u003cspan class=\"eyebrow\"\u003e09\u003c\/span\u003e\u003ch2\u003eRatings by platform\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e483+ REVIEWS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-reviews\"\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eDrugs.com\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 7.4\/10\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eAcne Rating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e151+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Can cause skin dryness, oiliness rebound, and does not work for all skin types — some users see no improvement after months of use.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eDrugs.com (All Uses)\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 6.8\/10\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eOverall Rating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e232+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eTotal Reviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: 27% of reviewers reported a negative experience, citing skin irritation, excessive dryness, and acne worsening before improvement.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eWebMD Reviews\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 7.2\/10\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e100+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Some users reported dizziness, oily skin rebound, and the product not preventing new breakouts — works better on existing pimples than prevention.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eAcne.org Community\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e Mixed\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eCommunity Sentiment\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e60%+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003ePositive Reports\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Works best when combined with benzoyl peroxide — users who use it alone often plateau or see resistance after several months of consistent use.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-pros-cons\"\u003e\n\u003cspan class=\"eyebrow\"\u003e10\u003c\/span\u003e\u003ch2\u003ePros \u0026amp; cons\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eBALANCED\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-proscons\"\u003e\n\u003cdiv class=\"pp-pc pros\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003ePraised\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Only 5 clean pharmaceutical-grade ingredients\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fast-absorbing, leaves no residue or sticky feel\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Genuinely effective for inflammatory acne (68% positive reviews)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fungal acne safe — no fatty acids or Malassezia triggers\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Oil-free, 0\/5 comedogenic — safe for oily and acne-prone skin\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fragrance-free and paraben-free\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Decades of clinical evidence and global dermatologist trust\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Works synergistically with retinoids and benzoyl peroxide\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Visible reduction in redness within days for many users\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Available in practical 30 mL and 60 mL applicator bottles\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-pc cons\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eCriticized\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e 50% isopropyl alcohol causes significant dryness for many users\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Prescription-only — requires a doctor visit to access\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Antibiotic resistance risk with prolonged monotherapy use\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Mild alcohol scent during application\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Less effective for non-inflammatory (comedonal) acne only\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Some users report skin oiliness rebound after extended use\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Contraindicated in GI history (colitis, Crohn's disease)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Not safe for direct use around the eyes — causes burning\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Results can plateau after 3+ months without complementary treatment\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Must continue consistently — acne can return if stopped prematurely\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-dupes\"\u003e\n\u003cspan class=\"eyebrow\"\u003e11\u003c\/span\u003e\u003ch2\u003eBudget-friendly alternatives (dupes)\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eDUPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-dupes\"\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match high\"\u003e92% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-phosphate-topical-solution\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/t92iu2xojulykd226a4bmrp4nxu6_square_c68719fd-0498-4e47-a990-333c884b91fd.png?v=1774354223\" alt=\"Clindamycin Phosphate Topical Solution\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-phosphate-topical-solution\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003eG\u0026amp;W Laboratories Clindamycin Phosphate Topical Solution USP 1%\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003eGeneric Rx\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eGeneric Pick\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eThe most direct pharmaceutical equivalent — identical active ingredient at 1%, identical vehicle formulation (IPA 50%, propylene glycol, water, NaOH). Bioequivalent to Cleocin T and Glasshouse's formulation. Widely available as a generic; ask your pharmacist for the generic option to reduce cost.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e70% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-phosphate-topical-lotion-1\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/q322hm707eglysxpgfrgkb6scfhg.jpg?v=1774098186\" alt=\"Clindamycin Phosphate Topical Lotion 1%\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-phosphate-topical-lotion-1\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003eGreenstone Brand Clindamycin Phosphate Topical Lotion 1%\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003eGeneric Rx\u003c\/div\u003e\n\u003cdiv class=\"tag similar\"\u003eLotion Format\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eSame active ingredient at 1% but in a lotion base — more hydrating and gentler on the skin barrier due to the addition of glycerin and other emollients. Better for dry or sensitive skin types who find the alcohol-heavy solution too drying. Contains some comedogenic-rated ingredients (glyceryl stearate, cetearyl alcohol) making it less suitable for very oily, acne-prone skin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e65% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"photo-fallback\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003eCleocin T (Brand Name) Clindamycin Phosphate Topical Solution 1%\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\u003cdiv class=\"amount\"\u003eBrand Rx\u003c\/div\u003e\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eThe original branded reference product that Glasshouse Pharmaceuticals' solution is bioequivalent to. Cleocin T features the same 5-ingredient formulation (clindamycin 1%, IPA 50%, propylene glycol, water, sodium hydroxide). Clinically identical in efficacy and safety. The Glasshouse generic offers the same results at a significantly lower cost.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-compare\"\u003e\n\u003cspan class=\"eyebrow\"\u003e12\u003c\/span\u003e\u003ch2\u003eComparison with competitors\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSIDE-BY-SIDE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-compare\"\u003e\n\u003cdiv class=\"pp-compare-card featured\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-phosphate-topical-solution\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/t92iu2xojulykd226a4bmrp4nxu6_square_c68719fd-0498-4e47-a990-333c884b91fd.png?v=1774354223\" alt=\"Clindamycin Phosphate Topical Solution\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-phosphate-topical-solution\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003eGlasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eClindamycin Phosphate 1%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFormulation\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eAlcohol-based liquid solution\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eIngredient Count\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003e5 (minimal)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFungal Acne Safe\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eComedogenic Rating\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003e0\/5\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFinish\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eMatte \/ Dry\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAvailability\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003ePrescription only\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Resistance Risk\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eYes (use with BPO)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-and-benzoyl-peroxide-gel-1-5\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/492v7xrd29s99wit964b0er1n5ra.jpg?v=1767016710\" alt=\"Clindamycin and Benzoyl Peroxide Gel 1%\/5%\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-and-benzoyl-peroxide-gel-1-5\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003ePerrigo Clindamycin + Benzoyl Peroxide Gel 1%\/5%\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eClindamycin 1% + BPO 5%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFormulation\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eGel base\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eIngredient Count\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003e9+ ingredients\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFungal Acne Safe\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eComedogenic Rating\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eLow (1\/5)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFinish\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eSlightly tacky gel\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAvailability\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003ePrescription only\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Resistance Risk\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eReduced (BPO protects)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003eDifferin (Adapalene 0.1% Gel) – Retinoid Alternative\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eAdapalene 0.1% (retinoid)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFormulation\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eLightweight gel\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eIngredient Count\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003e~10 ingredients\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFungal Acne Safe\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eComedogenic Rating\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003e0\/5\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFinish\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eSmooth gel\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAvailability\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eOTC (no prescription)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Resistance Risk\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eNone (not an antibiotic)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003eCabtreo (Clindamycin 1.2% + Ivermectin 0.15% + Adapalene 0.15%)\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eClindamycin + Retinoid + Antiparasitic\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFormulation\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eLotion\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eIngredient Count\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eMany (complex formulation)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFungal Acne Safe\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eVerify with pharmacist\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eComedogenic Rating\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eLow-moderate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFinish\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eCreamy lotion\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAvailability\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003ePrescription only\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic Resistance Risk\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eModerate (contains clindamycin)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-storage\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eStorage \u0026amp; shelf life\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e12 MONTHS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePeriod After Opening (PAO)\u003c\/strong\u003e\n\u003cp\u003e12 months after opening. Keep container tightly closed when not in use to prevent evaporation of the isopropyl alcohol base and degradation of the active ingredient.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eStorage\u003c\/strong\u003e\n\u003cp\u003eStore at controlled room temperature 20–25°C (68–77°F). Protect from freezing — freezing may destabilize the formulation and alter the pH balance needed for clindamycin efficacy.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePackaging\u003c\/strong\u003e\n\u003cp\u003eApplicator bottle with precision tip (30 mL or 60 mL). The applicator tip dispenses controlled amounts for targeted or full-face application using a dabbing motion — do not roll the applicator tip across skin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-package\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTravel Friendly\u003c\/strong\u003e\n\u003cp\u003eYes — the 30 mL bottle is TSA-compliant (under 100 mL) and can be carried in your hand luggage. Keep upright and tightly capped during travel to prevent leakage of the alcohol-based solution.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-faq\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eFAQ\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n\n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq1\"\u003e\n\u003clabel for=\"faq1\"\u003eIs Clindamycin Phosphate Topical Solution pregnancy and breastfeeding safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eUse with caution during pregnancy — only if clearly prescribed and deemed necessary by your healthcare provider. Systemic clindamycin administered during the second and third trimesters has not been associated with an increased frequency of congenital abnormalities in clinical trials. However, topical application can result in some systemic absorption through the skin. It is not known with certainty whether topically absorbed clindamycin passes into breast milk in significant amounts, though oral forms are known to do so. Always consult your OB-GYN or midwife before using any prescription topical antibiotic during pregnancy or while breastfeeding.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq2\"\u003e\n\u003clabel for=\"faq2\"\u003eIs Clindamycin Phosphate Topical Solution fungal acne (malassezia) safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eYes — this is one of the most fungal-acne-safe prescription acne treatments available. The Glasshouse Pharmaceuticals formulation contains only 5 ingredients: isopropyl alcohol, water, propylene glycol, clindamycin phosphate, and sodium hydroxide. None of these ingredients are fatty acids, fermented ingredients, esters, or polysorbates that feed Malassezia yeast. Clindamycin itself is an antibacterial antibiotic — it does not disrupt or worsen fungal conditions. If you suffer from pityrosporum folliculitis (fungal acne) alongside bacterial acne, this topical solution is a safe prescription option to discuss with your dermatologist.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq3\"\u003e\n\u003clabel for=\"faq3\"\u003eCan I use Clindamycin Phosphate Topical Solution with retinol, vitamin C, AHAs, or BHAs?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eClindamycin 1% solution can be combined with retinoids (tretinoin, adapalene, retinol) — in fact, this is a frequently prescribed combination as retinoids address comedonal acne while clindamycin targets inflammatory lesions. Apply them at different times (e.g., clindamycin in the morning, retinoid at night) to minimize irritation. Combining clindamycin with vitamin C (ascorbic acid) is generally fine, as they address different concerns. With AHAs and BHAs: layering multiple actives increases irritation risk given the already high alcohol content. If using chemical exfoliants, apply them at a separate time and start slowly. Benzoyl peroxide (BPO) is the most recommended combination partner — always apply BPO and clindamycin at different times of day to prevent potential inactivation and to protect against antibiotic resistance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq4\"\u003e\n\u003clabel for=\"faq4\"\u003eWhat skin type is Clindamycin Phosphate Topical Solution best for?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eThis solution is best suited for oily, acne-prone, and combination skin types with inflammatory acne (red, swollen pimples). The alcohol-based, oil-free formulation is ideal for oily skin — it absorbs instantly, leaves a matte finish, and does not add grease or clog pores (comedogenic rating: 0\/5). It is also excellent for those prone to fungal acne alongside bacterial acne. It is less ideal for dry skin or sensitive skin types due to the high 50% isopropyl alcohol content, which can cause dryness, tightness, and stinging. Dry-skinned users should follow immediately with a rich, non-comedogenic moisturizer and may wish to use it once daily rather than twice until tolerance builds.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq5\"\u003e\n\u003clabel for=\"faq5\"\u003eHow long until I see results from Clindamycin Phosphate Topical Solution?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eMost users notice initial improvement — particularly in redness and swelling of existing pimples — within the first 1–2 weeks. Meaningful reduction in the number of breakouts typically becomes evident between weeks 4 and 6 with consistent twice-daily application. Full therapeutic benefit is generally assessed at 8–12 weeks, which is the clinical standard for evaluating topical antibiotic efficacy. According to Mayo Clinic guidance and clinical literature, if no improvement is seen after 6 weeks, or if acne worsens, consult your dermatologist to reassess your treatment plan. Consistency is critical — missing applications significantly reduces efficacy.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq6\"\u003e\n\u003clabel for=\"faq6\"\u003eWhere does Clindamycin Phosphate Topical Solution go in my skincare routine?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eApply Clindamycin Phosphate Topical Solution as Step 3 in your routine: after cleansing and toning, before serums and moisturizers. The correct order is: Cleanser → Toner (optional) → Clindamycin Solution → Wait 5–10 minutes for full drying → Serum → Moisturizer → Sunscreen (AM only). The solution should always be applied to clean, dry skin. Do not apply other products on top until the solution is fully dry. If you use benzoyl peroxide, apply it at a completely different time of day (e.g., clindamycin in the PM, BPO in the AM) to avoid potential interaction and to reduce antibiotic resistance development.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq7\"\u003e\n\u003clabel for=\"faq7\"\u003eIs Clindamycin Phosphate Topical Solution comedogenic \/ will it clog pores?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eNo — this product is non-comedogenic and rates 0\/5 on the comedogenic scale. None of its 5 ingredients (isopropyl alcohol, water, propylene glycol, clindamycin phosphate, sodium hydroxide) are known to clog pores. The formula contains no oils, waxes, fatty acids, silicones, or any other ingredients associated with pore blockage. In fact, the 50% isopropyl alcohol base is well-known for its de-greasing, pore-clarifying properties. This makes the solution an appropriate choice for acne-prone skin where pore-clogging is a significant concern.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq8\"\u003e\n\u003clabel for=\"faq8\"\u003eHow long does Clindamycin Phosphate Topical Solution last after opening?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eThe Period After Opening (PAO) for Clindamycin Phosphate Topical Solution USP 1% is 12 months. Store at controlled room temperature of 20–25°C (68–77°F) and protect from freezing. Always keep the applicator cap tightly closed when not in use to prevent evaporation of the isopropyl alcohol vehicle and potential concentration changes or contamination. The 30 mL bottle provides approximately a 1-month supply when used twice daily as directed, so the full bottle will typically be used well within its PAO window. The 60 mL bottle provides approximately a 2-month supply. Discard if the solution changes color, develops unusual particles, or smells different from normal.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-verdict\"\u003e\n    \u003cdiv class=\"eyebrow\"\u003e— Skincarisma verdict\u003c\/div\u003e\n    \u003cdiv class=\"score-row\"\u003e\n      \u003cspan class=\"score\"\u003e4.2\u003c\/span\u003e\n      \u003cspan class=\"max\"\u003e\/ 5\u003c\/span\u003e\n      \u003cspan class=\"stars\"\u003e★★★★☆\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"text\"\u003e\n\u003cstrong\u003eVerdict:\u003c\/strong\u003e Glasshouse Pharmaceuticals Clindamycin Phosphate Topical Solution USP 1% is a\u003cstrong\u003eclinically proven, pharmaceutical-grade prescription antibiotic\u003c\/strong\u003e that delivers real results for mild-to-moderate inflammatory acne. Its standout strength lies in its exceptional formulation purity — just 5 ingredients, zero pore-cloggers, zero fungal-acne triggers, and zero fragrance. For oily and acne-prone skin types, it is among the cleanest, most effective topical antibiotic options on the market. The high isopropyl alcohol content (50%) makes it drying for sensitive and dry skin types, and antibiotic resistance risk means it should always be paired with benzoyl peroxide rather than used as monotherapy. When used correctly as part of a dermatologist-supervised routine — particularly combined with BPO or a retinoid — it is a powerfully effective tool in the fight against acne with decades of clinical evidence to back it up.\n\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003cbutton class=\"pp-back-to-top\" aria-label=\"Back to top\" type=\"button\" style=\"position:fixed;bottom:24px;right:24px;width:44px;height:44px;border-radius:50%;background:var(--pp-accent);color:#fff;border:none;display:none;cursor:pointer;z-index:50;box-shadow:0 4px 16px rgba(13,31,45,0.2)\"\u003e↑\u003c\/button\u003e\n  \u003cscript\u003e\n  (function () {\n    var btt = document.querySelector('.pp-back-to-top');\n    if (!btt) return;\n    var ticking = false;\n    function onScroll () {\n      if (!ticking) {\n        requestAnimationFrame(function () {\n          btt.style.display = window.scrollY \u003e 600 ? 'block' : 'none';\n          ticking = false;\n        });\n        ticking = true;\n      }\n    }\n    window.addEventListener('scroll', onScroll, { passive: true });\n    btt.addEventListener('click', function () { window.scrollTo({ top: 0, behavior: 'smooth' }); });\n  })();\n  \u003c\/script\u003e\n\u003c\/div\u003e\n","brand":"Glasshouse Pharmaceuticals","offers":[{"title":"Default Title","offer_id":52119885873495,"sku":null,"price":45.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/t92iu2xojulykd226a4bmrp4nxu6_square_c68719fd-0498-4e47-a990-333c884b91fd.png?v=1774354223","url":"https:\/\/www.skincarisma.com\/products\/clindamycin-phosphate-topical-solution","provider":"Skincarisma","version":"1.0","type":"link"}