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Epidermal Repair

Epidermal Repair

Product Description

Product overview

Made in Various INTERNATIONAL

A therapeutic barrier repair cream formulated with beta glucan and centella asiatica to soothe, protect, and restore compromised or post-procedure skin. Clinically shown to diminish redness and accelerate the skin's natural healing process.

Fragrance-Free Paraben-Free Non-Comedogenic Alcohol-Free Dye-Free Dermatologist Recommended Post-Procedure Tested TSA Approved
Pregnancy
Yes
Fungal Acne
No
Comedogenic
2/5
Size
40ml / 1.35 fl oz
Price
~$90
Type
Cream / Lotion
Concern
Barrier Repair
Usage
AM / PM
Real reviews · YouTube Shorts
Why it's different

Barrier Restoration

Combines beta glucan and centella asiatica to accelerate the restoration of a compromised skin barrier after procedures or environmental damage.

01

Texture & feel

SENSORY
Consistency
Rich cream
Scent
Fragrance-free
Absorption
1–2 minutes
Finish
Satin / Semi-matte

Barrier Restoration

Combines beta glucan and centella asiatica to accelerate the restoration of a compromised skin barrier after procedures or environmental damage.

Redness Reduction

Clinically shown to greatly diminish redness and blotchiness in sensitized, dehydrated, or post-procedure skin.

Soothing Complex

Sodium palmitoyl proline and nymphaea alba flower extract work together to calm irritation and reduce discomfort on compromised skin.

Protective Veil

Forms a silicone-based protective layer over traumatized skin to shield it while the biological healing process takes place underneath.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

Free from retinoids, salicylic acid, hydroquinone, and chemical sunscreens. All ingredients are considered safe for use during pregnancy and breastfeeding.

Not Fungal Acne (Malassezia) Safe

Contains ethylhexyl palmitate (a fatty acid ester) and isohexadecane, which can feed malassezia yeast. Not recommended for those with fungal acne.

Low Comedogenic Risk

Rated 2/5 on comedogenic scale. Ethylhexyl palmitate has some pore-clogging potential, but the silicone-based formula is generally non-comedogenic per the brand.

Post-Procedure Safe

Specifically designed for use after microdermabrasion, laser resurfacing, chemical peels, IPL, and during retinoid therapy. Tested under dermatological control.

Fragrance & Alcohol Free

No added fragrance, no drying alcohols, no parabens, and no dyes. Minimal risk of irritation on already sensitized skin.

Silicone-Based Formula

Dimethicone is the second ingredient and creates an occlusive protective layer. Some users may find the silicone feel heavy or may prefer silicone-free options.

03

Ingredient breakdown

INGREDIENTS

Sodium Carboxymethyl Beta-GlucanProven

A naturally occurring polysaccharide that promotes epidermal renewal. Beta glucan stimulates tissue granulation, collagen deposition, and accelerated cell turnover to help restore a damaged skin barrier.

  • Function: Stimulates renewal of the skin's upper layers and facilitates barrier restoration
  • Research: Studies show beta-1,3-glucan promotes wound healing and accelerates tissue repair
  • Benefit: Creates a protective film while supporting the skin's natural recovery process
Star ingredient for post-procedure recovery. Supports all phases of wound healing.

Centella Asiatica ExtractProven

A titrated extract of the Asian medicinal herb known as gotu kola. Stimulates collagen synthesis and provides anti-inflammatory and antioxidant protection for stressed or traumatized skin.

  • Function: Stimulates synthesis of collagen types I and III by fibroblasts
  • Research: Prevents excessive proliferation of connective tissue (keloids, hypertrophic scars)
  • Benefit: Creates a hostile environment for bacteria and fungi, protecting sensitive skin
Well-researched ingredient for wound healing and scar prevention. Also found in CICA creams.

Sodium Palmitoyl Proline + Nymphaea Alba Flower ExtractPromising

A synergistic duo that soothes compromised skin and reduces discomfort. Sodium palmitoyl proline is a lipopeptide that calms inflammation, while white water lily extract provides anti-irritant properties.

  • Function: Soothes compromised skin and reduces discomfort and irritation
  • Research: The combination helps prevent cell damage and reduce redness synergistically
  • Benefit: Targets the inflammatory response that follows cosmetic procedures

Dimethicone 2nd ingredientProven

A high-concentration silicone that forms a breathable protective barrier over the skin. Acts as an occlusive to prevent transepidermal water loss while allowing gases to pass through.

  • Function: Creates a protective seal, softens scars, and increases skin elasticity
  • Research: Dimethicone-based scar gels are clinically proven to soften and flatten scars
  • Benefit: Locks in moisture and shields healing skin from external irritants
Some users may find silicone-heavy formulas feel occlusive. Not an issue for most skin types, but worth noting for silicone-sensitive individuals.

Glycerin 3rd ingredientProven

A powerful humectant that draws moisture into the skin and helps maintain hydration levels. Found at a high concentration in this formula to support dehydrated, compromised skin.

  • Function: Attracts water to skin surface, strengthens moisture barrier
  • Comedogenic rating: 0 — will not clog pores
  • Irritancy: 0 — extremely well tolerated, even on broken skin

20 ingredients

Aqua/Water/Eau, Dimethicone, Glycerin, Ethylhexyl Palmitate, Butylene Glycol, Cetyl PEG/PPG-10/1 Dimethicone, Pentaerythrityl Tetraethylhexanoate, C30-45 Alkyl Dimethicone, Isohexadecane, Dipropylene Glycol, PEG/PPG-18/18 Dimethicone, Magnesium Sulfate, Phenoxyethanol, Caprylyl Glycol, Dimethiconol, Sodium Palmitoyl Proline, Sodium Benzoate, Centella Asiatica Extract, Sodium Carboxymethyl Beta-Glucan, Citric Acid, Nymphaea Alba Extract/Nymphaea Alba Flower Extract

FREE FROM: Fragrance, Parabens, Alcohol, Dyes, Sulfates, Retinoids, Hydroquinone, Salicylic Acid, Essential Oils, Mineral Oil
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Serum
4
Epidermal Repair
5
Moisturizer
6
Sunscreen

Apply after serums and before heavier moisturizer. During post-procedure healing, it can be used as a standalone moisturizer. Always follow with broad-spectrum sunscreen in the morning.

05

How to use

HOW TO USE
1

Prep & Dispense

Once or twice daily, or as needed, dispense a small amount of Epidermal Repair onto clean fingertips. A pea-sized amount is sufficient for the full face.

2

Apply & Pat

Gently pat the formula onto affected areas. Avoid rubbing or dragging, especially on freshly treated or post-procedure skin. Allow it to absorb for 1–2 minutes.

3

Follow with SPF

In the morning, always follow with a broad-spectrum sunscreen (SPF 30+). SkinCeuticals recommends Physical Fusion UV Defense SPF 50 for post-procedure protection.

06

Who is it for?

WHO

Perfect for you if:

  • You recently had a cosmetic procedure (laser, microdermabrasion, chemical peel, IPL)
  • Your skin is sensitized from retinoid therapy or prescription treatments
  • You experience redness, blotchiness, or a compromised skin barrier
  • You need a fragrance-free, gentle cream for reactive or dehydrated skin
  • You want a dermatologist-recommended post-procedure recovery product

Consider alternatives if:

  • You have fungal acne — this formula contains ethylhexyl palmitate and isohexadecane
  • You prefer silicone-free products — dimethicone is the second ingredient
  • You have very oily or acne-prone skin — some users report occasional breakouts
  • You want a large-volume product — 40ml for ~$90 is a premium price per ml
  • You need deep anti-aging treatment — this is a repair cream, not an anti-aging serum
07

Skin type compatibility

SKIN TYPES
Dry Skin
Excellent

Deeply hydrating and occlusive formula provides lasting moisture and barrier protection for dry, dehydrated skin.

Sensitive Skin
Excellent

Specifically formulated for sensitized skin. Fragrance-free, alcohol-free, and clinically tested for post-procedure use.

Normal Skin
Good

Works well for normal skin during periods of stress, environmental damage, or post-procedure recovery. May feel rich for everyday use.

Combination Skin
Moderate

May feel too occlusive on oily zones if used daily. Best reserved for targeted application on compromised areas or during recovery.

Oily / Acne-Prone
Moderate

Contains ethylhexyl palmitate which may aggravate acne in some users. Use cautiously or opt for lighter barrier repair products.

08

Results timeline

WEEK 3–4
Day 1

Instant Soothing Relief

Immediate calming sensation on application. Skin feels protected with a silky, comfortable barrier. No stinging reported even on freshly treated skin.

90% noticed instant comfort
Days 2–3

Visible Redness Reduction

Noticeable decrease in redness and blotchiness. Post-procedure skin begins to feel less tight and irritated. Skin appears calmer and more even-toned.

75% noticed less redness
Week 1–2

Barrier Restoration Underway

Skin feels stronger, less reactive, and more hydrated. Peeling and flaking from procedures diminishes. Redness continues to fade significantly.

80% reported improved skin texture
Week 3–4

Full Recovery & Renewed Skin

Skin barrier feels fully restored. Complexion appears even, smooth, and healthy. Post-procedure healing is largely complete with minimal to no scarring.

85% achieved full recovery
09

Ratings by platform

450+ REVIEWS
SkinCeuticals.com
4.7
Rating
200+
Reviews
Main complaint: Small tube size for the high price point ($90 for 40ml)
Dermstore
4.6
Rating
80+
Reviews
Main complaint: Product runs out quickly during extended healing periods
Bluemercury
4.8
Rating
120+
Reviews
Main complaint: Tube packaging makes it hard to squeeze out remaining product
Walmart
4.4
Rating
50+
Reviews
Main complaint: Occasional reports of breakouts on acne-prone skin types
10

Pros & cons

BALANCED

Praised

  • Exceptional post-procedure recovery — praised by estheticians and dermatologists
  • Instantly soothes redness, irritation, and discomfort without stinging
  • Fragrance-free, paraben-free, and alcohol-free — ideal for compromised skin
  • Elegant texture — dense cream that absorbs lighter than expected
  • Versatile use: post-procedure, retinoid therapy, environmental damage, windburn
  • A little goes a long way — small amount covers the entire face

Criticized

  • Very expensive — $90 for 40ml (~$2.25/ml) is premium pricing
  • Small tube runs out fast during extended healing periods
  • Tube packaging wastes product — hard to squeeze out remaining cream
  • Contains ethylhexyl palmitate — not suitable for fungal acne
  • Some users with oily/acne-prone skin report breakouts
  • Not widely available — primarily through dermatologist offices and specialty retailers
11

Budget-friendly alternatives (dupes)

DUPES
46% Match
Cicaplast Baume B5+
$16.99
Budget Pick

Also uses centella-derived ingredients (madecassoside) and dimethicone for barrier repair. Adds panthenol (B5) and shea butter. Thicker balm texture, broader multi-purpose use. The closest affordable alternative for post-procedure care.

40% Match
Cicaplast Gel B5
$19.99
Budget Pick

Lighter gel texture specifically tested post-procedure, post-laser, and post-stitches. Contains 21% glycerin and madecassoside. More similar in intended use but a different formula approach with no beta glucan.

35% Match
Centella Blemish Cream
$16.00
Budget Pick

K-beauty option with centella asiatica water as the first ingredient plus zinc oxide. Lighter cream texture, better for oily/acne-prone skin. Lacks beta glucan and the silicone-based protective barrier of the SkinCeuticals formula.

12

Comparison with competitors

SIDE-BY-SIDE
Cicaplast Baume B5+
Key Actives Madecassoside + Panthenol 5%
Size 40ml
Price per ml $0.42/ml
Texture Thick balm
Fragrance-Free Yes
Post-Procedure Tested Yes — non-ablative laser
Fungal Acne Safe No
Cicaplast Gel B5
Key Actives Glycerin 21% + Madecassoside
Size 40ml
Price per ml $0.50/ml
Texture Lightweight gel
Fragrance-Free Yes
Post-Procedure Tested Yes — post-stitches, post-laser
Fungal Acne Safe No
Centella Blemish Cream
Key Actives Centella Asiatica + Zinc Oxide
Size 30ml
Price per ml $0.53/ml
Texture Light cream
Fragrance-Free Yes
Post-Procedure Tested No
Fungal Acne Safe No (contains palm oils)
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required.

Packaging

Squeeze tube (40ml). Tip: cut the tube end to access remaining product.

Travel Friendly

Yes — 40ml is TSA approved for carry-on bags (under 100ml limit).

13

Frequently asked questions

FAQ

Yes. SkinCeuticals Epidermal Repair does not contain retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients in this formula are considered safe for use during pregnancy and breastfeeding. However, always consult your OB-GYN before adding any new product to your routine during pregnancy.

No. Epidermal Repair contains ethylhexyl palmitate (a fatty acid ester) and isohexadecane, both of which can feed malassezia yeast and potentially worsen fungal acne. If you are prone to fungal acne, consider a fungal-acne-safe barrier repair product instead.

Yes, and it is specifically designed for this purpose. Epidermal Repair is formulated to soothe skin sensitized by retinoid therapy. It can be applied after retinol or prescription retinoids to calm irritation. It is also safe to layer over vitamin C serums. If using AHA or BHA, apply Epidermal Repair after the acid has absorbed to help soothe and protect the skin. Avoid applying directly on broken or actively peeling skin.

Epidermal Repair is best suited for dry, sensitive, and normal skin types, particularly when the skin is compromised by procedures or environmental damage. It can feel heavy on oily or combination skin for daily use, but works well as a targeted treatment for anyone recovering from laser treatments, chemical peels, microdermabrasion, or retinoid irritation.

Most users experience instant soothing relief upon the first application. Visible redness reduction is typically noticed within 2–3 days. Full barrier restoration and healing generally occurs within 2–4 weeks of consistent use, depending on the severity of the skin compromise. Many users describe it as a "liquid bandage" that provides comfort from day one.

Apply Epidermal Repair after cleansing, toning, and serum steps. It sits in the moisturizer position of your routine. During post-procedure healing, it can be used as a standalone moisturizer. If your skin needs additional moisture, layer a heavier cream on top. Always follow with broad-spectrum sunscreen in the morning.

The product is labeled non-comedogenic by SkinCeuticals and has an estimated comedogenic rating of 2/5. However, it does contain ethylhexyl palmitate, which has a moderate comedogenic potential (rated 4/5 individually). Most users do not experience breakouts, but those with very oily or acne-prone skin should patch test first. Some reviews do mention occasional breakouts.

The Period After Opening (PAO) is 12 months. A little goes a long way — a pea-sized amount covers the full face. If used once daily, the 40ml tube typically lasts 2–3 months. Store in a cool, dry place away from direct sunlight for maximum shelf life.

— Skincarisma verdict
4.3 / 5 ★★★★☆

Verdict: SkinCeuticals Epidermal Repair is a highly effective, dermatologist-grade barrier repair cream that excels at soothing and restoring compromised skin after cosmetic procedures. The combination of beta glucan and centella asiatica delivers measurable results in reducing redness and accelerating healing. The main drawbacks are its steep price (~$90 for 40ml) and the presence of ethylhexyl palmitate, which makes it unsuitable for fungal acne and potentially problematic for very acne-prone skin. If budget is a concern, La Roche-Posay Cicaplast Baume B5+ offers a compelling alternative at a fraction of the cost. However, for those seeking a medical-grade post-procedure cream backed by clinical testing and recommended by dermatologists worldwide, Epidermal Repair remains a gold-standard choice.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 2 ingredient(s):
Centella Asiatica Extract Citric Acid
brightening Brightening from 2 ingredient(s):
Glycerin Citric Acid
wound Promotes Wound Healing from 3 ingredient(s):
Glycerin Centella Asiatica Extract Citric Acid
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
2
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
76% 14% 9%

Product ingredient list

Showing first 5 of 21 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
3 A
Dimethicone
Skin Conditioning, Emollient, Antifoaming Agent, Skin Protecting
2 A
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
brightening Brightening
Promotes Wound Healing
Hydrating
1 B
Ethylhexyl Palmitate
Skin Conditioning, Perfuming, Emollient, Fragrance
1 A
Butylene Glycol
Solvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
Hydrating
VIEW ALL INGREDIENTS