{"product_id":"epiduo-gel-0-1-2-5","title":"Epiduo Gel 0.1%\/2.5%","description":"\u003cdiv class=\"pp\" lang=\"en\" itemscope itemtype=\"https:\/\/schema.org\/Product\"\u003e\n  \u003cmeta itemprop=\"name\" content=\"Galderma Epiduo Gel 0.1%\/2.5%\"\u003e\n  \u003cmeta itemprop=\"brand\" content=\"Galderma\"\u003e\n  \u003cmeta itemprop=\"category\" content=\"Skincare \u0026gt; Acne Treatment\"\u003e\n  \u003cmeta itemprop=\"countryOfOrigin\" content=\"Various\"\u003e\n\n  \u003cscript type=\"application\/ld+json\"\u003e{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"FAQPage\",\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Epiduo Gel pregnancy and breastfeeding safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No, Epiduo is not safe during pregnancy. It contains adapalene, a retinoid, and all retinoids are contraindicated in pregnancy due to the potential risk of birth defects. If you become pregnant while using Epiduo, discontinue immediately and consult your doctor. For breastfeeding, the European SmPC states that Epiduo can be used during breastfeeding since systemic exposure is negligible, but you should avoid applying it to the chest area. Always consult your healthcare provider for personalized guidance.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Epiduo Gel fungal acne (malassezia) safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No, Epiduo is not considered fungal acne safe. The formula contains polysorbate 80 and sorbitan oleate, which are known triggers for malassezia (fungal acne). Sorbitan oleate in particular has a medium comedogenicity risk for fungal acne. If you have malassezia folliculitis, consider alternatives like azelaic acid (Finacea) or pure benzoyl peroxide wash formulations without these emulsifiers.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can I use Epiduo Gel with retinol, vitamin C, AHA, or BHA?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Use extreme caution when combining Epiduo with other active ingredients. Avoid using additional retinoids (retinol, tretinoin) as this can cause severe irritation. Avoid AHAs (glycolic acid, lactic acid) and BHAs (salicylic acid) on the same night as Epiduo, as the cumulative exfoliating effects can damage your skin barrier. Vitamin C (L-ascorbic acid) is best used in the AM while Epiduo stays in your PM routine. Always introduce new actives gradually and consult your dermatologist before combining treatments.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What skin type is Epiduo Gel best for?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Epiduo works best for oily, combination, and acne-prone skin types. The gel formula absorbs cleanly and helps control excess oil production. It can also be used on normal skin with appropriate moisturizer support. Dry and sensitive skin types may find Epiduo too drying and irritating — these users should introduce the product very slowly (2x per week) and use the \\\"sandwich method\\\" (moisturizer-Epiduo-moisturizer) to buffer irritation.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long until I see results from Epiduo Gel?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Early signs of improvement typically appear within 1–4 weeks of consistent use. However, the full benefits may take 8–12 weeks. Many users report a \\\"purging\\\" phase in weeks 1–4 where acne temporarily worsens before it improves. Clinical trials show significant lesion reduction by week 12, with optimal results at 3–6 months. The key is persistence — do not stop using Epiduo during the purging phase unless advised by your dermatologist.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Where does Epiduo Gel go in my skincare routine?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Apply Epiduo in the evening only, after cleansing and drying your face completely. It goes on clean, dry skin as the treatment step before moisturizer. The routine order is: gentle cleanser, pat dry, Epiduo (pea-sized amounts), wait 5–10 minutes, then non-comedogenic moisturizer. In the morning, use a gentle cleanser, moisturizer, and broad-spectrum SPF 30+ sunscreen. Do not apply any other medicated products at the same time as Epiduo unless directed by your doctor.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Epiduo Gel comedogenic \/ will it clog pores?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Epiduo has a low comedogenic rating of 1\/5. The gel is formulated with a water-based vehicle and is free from oils, silicones, and heavy emollients. It is specifically designed to unclog pores rather than block them. However, it does contain sorbitan oleate, which has medium comedogenicity for fungal acne specifically. For traditional comedonal acne, Epiduo actively helps clear and prevent clogged pores.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long does Epiduo Gel last after opening?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Epiduo Forte has a labeled shelf life of 3 months after opening. Standard Epiduo should be used before the expiration date printed on the tube or carton. Store at room temperature (20–25°C \/ 68–77°F), keep the tube tightly closed, and protect it from light and heat. Do not use if the gel has changed color, texture, or consistency. One 45g tube typically lasts 1–3 months with regular once-daily use on the face.\"\n          }\n        }\n      ]\n    },\n    {\n      \"@type\": \"HowTo\",\n      \"name\": \"How to use Galderma Epiduo Gel 0.1%\/2.5%\",\n      \"totalTime\": \"PT2M\",\n      \"step\": [\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 1,\n          \"name\": \"Cleanse\",\n          \"text\": \"Wash your face with a gentle, non-medicated cleanser (e.g., Cetaphil or CeraVe). Pat skin completely dry with a clean towel.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 2,\n          \"name\": \"Apply a Pea-Sized Amount\",\n          \"text\": \"Use one pea-sized amount for each area: forehead, each cheek, and chin. Apply as a thin film across the entire affected area, not just individual spots.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 3,\n          \"name\": \"Avoid Sensitive Areas\",\n          \"text\": \"Keep away from eyes, lips, nostrils, and any broken, sunburned, or eczema-affected skin. If contact occurs, rinse immediately with warm water.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 4,\n          \"name\": \"Moisturize\",\n          \"text\": \"Wait 5–10 minutes for Epiduo to absorb, then apply a non-comedogenic moisturizer to counteract dryness and support the skin barrier.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 5,\n          \"name\": \"Build Tolerance Gradually\",\n          \"text\": \"Week 1: apply every other night. Week 2: apply 3–4 nights. Week 3+: increase to nightly use as tolerated. Reduce frequency if excessive irritation occurs.\"\n        }\n      ]\n    },\n    {\n      \"@type\": \"ItemList\",\n      \"name\": \"Galderma Epiduo Gel 0.1%\/2.5% — Ingredients (INCI)\",\n      \"numberOfItems\": 11,\n      \"itemListElement\": [\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 1,\n          \"name\": \"Active: Adapalene (0.1%)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 2,\n          \"name\": \"Benzoyl Peroxide (2.5%). Inactive: Acrylamide\/Sodium Acryloyldimethyltaurate Copolymer\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 3,\n          \"name\": \"Docusate Sodium\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 4,\n          \"name\": \"Edetate Disodium\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 5,\n          \"name\": \"Glycerin\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 6,\n          \"name\": \"Isohexadecane\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 7,\n          \"name\": \"Poloxamer 124\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 8,\n          \"name\": \"Polysorbate 80\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 9,\n          \"name\": \"Propylene Glycol\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 10,\n          \"name\": \"Purified Water\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 11,\n          \"name\": \"Sorbitan Oleate.\"\n        }\n      ]\n    }\n  ]\n}\u003c\/script\u003e\n\n  \u003csvg width=\"0\" height=\"0\" style=\"position:absolute\" aria-hidden=\"true\" focusable=\"false\"\u003e\n    \u003cdefs\u003e\n      \u003csymbol id=\"i-check\" viewbox=\"0 0 24 24\"\u003e\u003cpolyline points=\"20 6 9 17 4 12\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-x\" viewbox=\"0 0 24 24\"\u003e\u003cline x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-plus\" viewbox=\"0 0 24 24\"\u003e\u003cline x1=\"12\" y1=\"5\" x2=\"12\" y2=\"19\"\u003e\u003c\/line\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-chev-down\" viewbox=\"0 0 24 24\"\u003e\u003cpolyline points=\"6 9 12 15 18 9\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-shield\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M12 2L4 6v6c0 5 3.5 9.5 8 10 4.5-.5 8-5 8-10V6l-8-4z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-shield-check\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M12 2L4 6v6c0 5 3.5 9.5 8 10 4.5-.5 8-5 8-10V6l-8-4z\"\u003e\u003c\/path\u003e\u003cpolyline points=\"9 12 11 14 15 10\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-flask\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M9 2v6L4 18a2 2 0 002 3h12a2 2 0 002-3l-5-10V2\"\u003e\u003c\/path\u003e\u003cline x1=\"8\" y1=\"2\" x2=\"16\" y2=\"2\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-leaf\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M6 22c0-8 6-14 14-14 0 8-6 14-14 14z\"\u003e\u003c\/path\u003e\u003cpath d=\"M6 22c4-8 10-12 14-12\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-droplet\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M12 2.5l5.5 7a7 7 0 11-11 0L12 2.5z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-sparkle\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M12 2l2 6 6 2-6 2-2 6-2-6-6-2 6-2 2-6z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-star\" viewbox=\"0 0 24 24\"\u003e\u003cpolygon points=\"12 2 15 9 22 10 17 15 18 22 12 19 6 22 7 15 2 10 9 9 12 2\"\u003e\u003c\/polygon\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-clock\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"9\"\u003e\u003c\/circle\u003e\u003cpolyline points=\"12 7 12 12 15 14\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-sun\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"4\"\u003e\u003c\/circle\u003e\u003cline x1=\"12\" y1=\"2\" x2=\"12\" y2=\"5\"\u003e\u003c\/line\u003e\u003cline x1=\"12\" y1=\"19\" x2=\"12\" y2=\"22\"\u003e\u003c\/line\u003e\u003cline x1=\"4.2\" y1=\"4.2\" x2=\"6.3\" y2=\"6.3\"\u003e\u003c\/line\u003e\u003cline x1=\"17.7\" y1=\"17.7\" x2=\"19.8\" y2=\"19.8\"\u003e\u003c\/line\u003e\u003cline x1=\"2\" y1=\"12\" x2=\"5\" y2=\"12\"\u003e\u003c\/line\u003e\u003cline x1=\"19\" y1=\"12\" x2=\"22\" y2=\"12\"\u003e\u003c\/line\u003e\u003cline x1=\"4.2\" y1=\"19.8\" x2=\"6.3\" y2=\"17.7\"\u003e\u003c\/line\u003e\u003cline x1=\"17.7\" y1=\"6.3\" x2=\"19.8\" y2=\"4.2\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-wind\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M3 8h11a3 3 0 100-6\"\u003e\u003c\/path\u003e\u003cpath d=\"M3 16h15a3 3 0 110 6\"\u003e\u003c\/path\u003e\u003cpath d=\"M3 12h18\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-target\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"9\"\u003e\u003c\/circle\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"5\"\u003e\u003c\/circle\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"1.5\" fill=\"currentColor\" stroke=\"none\"\u003e\u003c\/circle\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-bottle\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M10 2h4v4l1 2v11a3 3 0 01-3 3h-0a3 3 0 01-3-3V8l1-2V2z\"\u003e\u003c\/path\u003e\u003cline x1=\"9\" y1=\"13\" x2=\"15\" y2=\"13\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-trending\" viewbox=\"0 0 24 24\"\u003e\u003cpolyline points=\"3 17 9 11 13 15 21 7\"\u003e\u003c\/polyline\u003e\u003cpolyline points=\"15 7 21 7 21 13\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-refresh\" viewbox=\"0 0 24 24\"\u003e\u003cpolyline points=\"22 4 22 10 16 10\"\u003e\u003c\/polyline\u003e\u003cpolyline points=\"2 20 2 14 8 14\"\u003e\u003c\/polyline\u003e\u003cpath d=\"M22 10a10 10 0 00-18-3M2 14a10 10 0 0018 3\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-coin\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"9\"\u003e\u003c\/circle\u003e\u003cpath d=\"M12 7v10\"\u003e\u003c\/path\u003e\u003cpath d=\"M15 9.5a2.5 2.5 0 00-3-1c-1.5 0-2.5 1-2.5 2s1 1.5 2.5 2 2.5 1 2.5 2-1 2-2.5 2a2.5 2.5 0 01-3-1\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-scale\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M12 3v18\"\u003e\u003c\/path\u003e\u003cpath d=\"M6 21h12\"\u003e\u003c\/path\u003e\u003cpath d=\"M3 9l3-6 3 6c-1.5 2-4.5 2-6 0z\"\u003e\u003c\/path\u003e\u003cpath d=\"M15 9l3-6 3 6c-1.5 2-4.5 2-6 0z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-help\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"9\"\u003e\u003c\/circle\u003e\u003cpath d=\"M9.5 9a2.5 2.5 0 015 0c0 2-2.5 2-2.5 4\"\u003e\u003c\/path\u003e\u003cline x1=\"12\" y1=\"17\" x2=\"12\" y2=\"17.5\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-info\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"9\"\u003e\u003c\/circle\u003e\u003cline x1=\"12\" y1=\"11\" x2=\"12\" y2=\"16\"\u003e\u003c\/line\u003e\u003cline x1=\"12\" y1=\"8\" x2=\"12\" y2=\"8.5\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-pin\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M12 22s7-7 7-12a7 7 0 10-14 0c0 5 7 12 7 12z\"\u003e\u003c\/path\u003e\u003ccircle cx=\"12\" cy=\"10\" r=\"2.5\"\u003e\u003c\/circle\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-list\" viewbox=\"0 0 24 24\"\u003e\u003cline x1=\"9\" y1=\"6\" x2=\"20\" y2=\"6\"\u003e\u003c\/line\u003e\u003cline x1=\"9\" y1=\"12\" x2=\"20\" y2=\"12\"\u003e\u003c\/line\u003e\u003cline x1=\"9\" y1=\"18\" x2=\"20\" y2=\"18\"\u003e\u003c\/line\u003e\u003cline x1=\"4\" y1=\"6\" x2=\"4\" y2=\"6.01\"\u003e\u003c\/line\u003e\u003cline x1=\"4\" y1=\"12\" x2=\"4\" y2=\"12.01\"\u003e\u003c\/line\u003e\u003cline x1=\"4\" y1=\"18\" x2=\"4\" y2=\"18.01\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-cart\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"9\" cy=\"21\" r=\"1\"\u003e\u003c\/circle\u003e\u003ccircle cx=\"19\" cy=\"21\" r=\"1\"\u003e\u003c\/circle\u003e\u003cpath d=\"M2.5 3H5l2.7 13a2 2 0 002 1.6h8.4a2 2 0 002-1.6L22 7H6\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-globe\" viewbox=\"0 0 24 24\"\u003e\u003ccircle cx=\"12\" cy=\"12\" r=\"9\"\u003e\u003c\/circle\u003e\u003cline x1=\"3\" y1=\"12\" x2=\"21\" y2=\"12\"\u003e\u003c\/line\u003e\u003cpath d=\"M12 3c2.5 3 4 6 4 9s-1.5 6-4 9c-2.5-3-4-6-4-9s1.5-6 4-9z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-package\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M20 8l-8-4-8 4v8l8 4 8-4V8z\"\u003e\u003c\/path\u003e\u003cline x1=\"4\" y1=\"8\" x2=\"20\" y2=\"8\"\u003e\u003c\/line\u003e\u003cline x1=\"12\" y1=\"12\" x2=\"12\" y2=\"20\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-calendar\" viewbox=\"0 0 24 24\"\u003e\u003crect x=\"3\" y=\"5\" width=\"18\" height=\"16\" rx=\"2\"\u003e\u003c\/rect\u003e\u003cline x1=\"3\" y1=\"10\" x2=\"21\" y2=\"10\"\u003e\u003c\/line\u003e\u003cline x1=\"8\" y1=\"3\" x2=\"8\" y2=\"7\"\u003e\u003c\/line\u003e\u003cline x1=\"16\" y1=\"3\" x2=\"16\" y2=\"7\"\u003e\u003c\/line\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-home\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M3 11l9-7 9 7v9a2 2 0 01-2 2h-4v-7H9v7H5a2 2 0 01-2-2v-9z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-plane\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M22 12l-9 4-3 6-2-5-5-2 6-3 4-9 9 9z\"\u003e\u003c\/path\u003e\u003c\/symbol\u003e\n      \u003csymbol id=\"i-arrow-right\" viewbox=\"0 0 24 24\"\u003e\u003cline x1=\"5\" y1=\"12\" x2=\"19\" y2=\"12\"\u003e\u003c\/line\u003e\u003cpolyline points=\"12 5 19 12 12 19\"\u003e\u003c\/polyline\u003e\u003c\/symbol\u003e\n    \u003c\/defs\u003e\n  \u003c\/svg\u003e\n\n  \n  \u003csection id=\"pp-overview\" class=\"pp-hero\" aria-labelledby=\"pp-hero-title\"\u003e\n    \u003ch2 id=\"pp-hero-title\" class=\"pp-sr-only\" style=\"position:absolute;left:-10000px\"\u003eProduct overview\u003c\/h2\u003e\n    \u003cdiv class=\"pp-origin\"\u003e\n      \u003csvg class=\"pin\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-pin\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n      \u003cspan class=\"text\"\u003eMade in Various\u003c\/span\u003e\n      \u003cspan class=\"dot\"\u003e\u003c\/span\u003e\n      \u003cspan class=\"tag\"\u003eINTERNATIONAL\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"pp-subtitle\"\u003eEpiduo Gel 0.1%\/2.5% by Galderma is a prescription-strength dual-action acne treatment combining adapalene (a third-generation retinoid) with benzoyl peroxide in a single, once-daily gel. Clinically proven to reduce both inflammatory and non-inflammatory acne lesions, it targets clogged pores, kills acne-causing bacteria, and accelerates skin cell turnover for clearer, smoother skin.\u003c\/p\u003e\n    \u003cdiv class=\"pp-badges\"\u003e\n\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Prescription-Strength\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Dermatologist Recommended\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Antibiotic-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fragrance-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Paraben-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Oil-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Silicone-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e FDA Approved (2008)\u003c\/span\u003e\n\u003c\/div\u003e\n    \u003cnav class=\"pp-nav\" aria-label=\"Jump to product section\"\u003e\n      \u003cdiv class=\"pp-nav-head\"\u003eJump to section\u003c\/div\u003e\n      \u003cdiv class=\"pp-nav-list\"\u003e\n        \u003ca href=\"#pp-safety\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSafety\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-ingredients\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eIngredients\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-routine\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-refresh\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eRoutine\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-how-to-use\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eHow to use\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-skin-types\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSkin types\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-results\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-trending\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eResults\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-reviews\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-star\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eReviews\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-dupes\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-coin\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eDupes\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-faq\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-help\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eFAQ\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/nav\u003e\n    \n    \u003cdiv class=\"pp-scorecard\"\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003ePregnancy\u003c\/div\u003e\n\u003cdiv class=\"val warning\"\u003e\n\u003csvg class=\"x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e No\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eFungal Acne\u003c\/div\u003e\n\u003cdiv class=\"val warning\"\u003e\n\u003csvg class=\"x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e No\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eComedogenic\u003c\/div\u003e\n\u003cdiv class=\"val safe\"\u003e1\/5\u003c\/div\u003e\n\u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pp-specs\"\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eType\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eRx Gel\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eSize\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e45g \/ 60g\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eBrand\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eGalderma\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eTarget\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eAcne Vulgaris\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eActive\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eAdapalene + BP\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n    \n    \u003cdiv class=\"pp-videos\"\u003e\n      \u003cspan class=\"eyebrow\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-star\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Real reviews · YouTube Shorts\u003c\/span\u003e\n      \u003cdiv class=\"pp-videos-grid\"\u003e\n        \u003cdiv class=\"pp-videos-frame\"\u003e\n          \u003ciframe src=\"https:\/\/www.youtube.com\/embed\/xf7-Zx_h2fg?modestbranding=1\u0026amp;rel=0\u0026amp;playsinline=1\" title=\"YouTube Shorts review 1 — Galderma Epiduo Gel 0.1%\/2.5%\" loading=\"lazy\" allow=\"accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share; fullscreen\" allowfullscreen referrerpolicy=\"strict-origin-when-cross-origin\"\u003e\u003c\/iframe\u003e\n        \u003c\/div\u003e\n\u003cdiv class=\"pp-videos-frame\"\u003e\n          \u003ciframe src=\"https:\/\/www.youtube.com\/embed\/g3sWGLwHJz0?modestbranding=1\u0026amp;rel=0\u0026amp;playsinline=1\" title=\"YouTube Shorts review 2 — Galderma Epiduo Gel 0.1%\/2.5%\" loading=\"lazy\" allow=\"accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share; fullscreen\" allowfullscreen referrerpolicy=\"strict-origin-when-cross-origin\"\u003e\u003c\/iframe\u003e\n        \u003c\/div\u003e\n\u003cdiv class=\"pp-videos-frame\"\u003e\n          \u003ciframe src=\"https:\/\/www.youtube.com\/embed\/fOEU5ZQKFiM?modestbranding=1\u0026amp;rel=0\u0026amp;playsinline=1\" title=\"YouTube Shorts review 3 — Galderma Epiduo Gel 0.1%\/2.5%\" loading=\"lazy\" allow=\"accelerometer; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share; fullscreen\" allowfullscreen referrerpolicy=\"strict-origin-when-cross-origin\"\u003e\u003c\/iframe\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n    \n    \u003cdiv class=\"pp-highlight\"\u003e\n      \u003cspan class=\"eyebrow\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Why it's different\u003c\/span\u003e\n      \u003ch3\u003eDual-Action Formula\u003c\/h3\u003e\n      \u003cp\u003eCombines adapalene (retinoid) with benzoyl peroxide in one gel for both anti-inflammatory and antibacterial action against acne.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n\n  \u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-sensory\"\u003e\n\u003cspan class=\"eyebrow\"\u003e01\u003c\/span\u003e\u003ch2\u003eTexture \u0026amp; feel\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSENSORY\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-sensory\"\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eConsistency\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eOpaque Gel\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-wind\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eScent\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eFragrance-Free\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eAbsorption\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003e1–2 Minutes\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eFinish\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eMatte\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-features\"\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eDual-Action Formula\u003c\/h4\u003e\n\u003cp\u003eCombines adapalene (retinoid) with benzoyl peroxide in one gel for both anti-inflammatory and antibacterial action against acne.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eAntibiotic-Free\u003c\/h4\u003e\n\u003cp\u003eUnlike clindamycin-based treatments, Epiduo does not contribute to antibiotic resistance and can be used long-term.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-refresh\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eAccelerates Cell Turnover\u003c\/h4\u003e\n\u003cp\u003eAdapalene normalizes skin cell differentiation and prevents microcomedone formation, keeping pores clear from within.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eKills Acne Bacteria\u003c\/h4\u003e\n\u003cp\u003eBenzoyl peroxide releases oxygen into pores to eliminate P. acnes bacteria without causing bacterial resistance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-safety\"\u003e\n\u003cspan class=\"eyebrow\"\u003e02\u003c\/span\u003e\u003ch2\u003eSafety \u0026amp; compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSAFE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePregnancy: Not Safe\u003c\/strong\u003e\n\u003cp\u003eContains adapalene, a retinoid. Retinoids are contraindicated during pregnancy due to potential risk of birth defects. Discontinue if you become pregnant.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eBreastfeeding: Use with Caution\u003c\/strong\u003e\n\u003cp\u003eSystemic absorption is negligible, but avoid applying to the chest area. Consult your doctor before use while breastfeeding.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eFungal Acne (Malassezia): Not Safe\u003c\/strong\u003e\n\u003cp\u003eContains polysorbate 80 and sorbitan oleate, which are known triggers for fungal acne (malassezia folliculitis). Not recommended if you have fungal acne.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sun\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSun Sensitivity: Increased\u003c\/strong\u003e\n\u003cp\u003eAdapalene increases photosensitivity. Always use broad-spectrum SPF 30+ sunscreen during the day and avoid excessive sun exposure.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eAntibiotic Resistance: No Risk\u003c\/strong\u003e\n\u003cp\u003eEpiduo is antibiotic-free. Benzoyl peroxide kills bacteria through oxidation, so no bacterial resistance develops with long-term use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eInitial Irritation: Expected\u003c\/strong\u003e\n\u003cp\u003eDryness, redness, peeling, and stinging are common in weeks 1–4. Start slowly (every other day) and use a non-comedogenic moisturizer to manage irritation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eFabric Bleaching Warning\u003c\/strong\u003e\n\u003cp\u003eBenzoyl peroxide can bleach towels, pillowcases, and clothing. Use white bedding or apply old t-shirts when sleeping.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eLow Comedogenic Rating: 1\/5\u003c\/strong\u003e\n\u003cp\u003eThe water-based gel formula is non-comedogenic. Free from oils, silicones, and heavy emollients that can clog pores.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-ingredients\"\u003e\n\u003cspan class=\"eyebrow\"\u003e03\u003c\/span\u003e\u003ch2\u003eIngredient breakdown\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eINGREDIENTS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eAdapalene 0.1%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA third-generation synthetic retinoid that modulates skin cell differentiation, keratinization, and inflammation. It penetrates deep into pores to prevent microcomedone formation and reduce existing acne lesions.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism:\u003c\/strong\u003e Binds to specific retinoic acid nuclear receptors (RAR-gamma) to normalize cell turnover\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical data:\u003c\/strong\u003e In two 12-week trials with 2,185 patients, Epiduo achieved 62% lesion reduction vs 50–55% for individual components alone\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-aging bonus:\u003c\/strong\u003e Also helps reduce fine lines, improve skin texture, and even skin tone over time\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eCauses photosensitivity. Always use SPF 30+ sunscreen during the day. May cause initial purging in weeks 1–4.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eBenzoyl Peroxide 2.5%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA highly lipophilic oxidizing agent that kills Cutibacterium acnes (P. acnes) bacteria by releasing oxygen into the pores. Also provides keratolytic (exfoliating) effects to unclog pores.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eEfficacy:\u003c\/strong\u003e 2.5% concentration is shown to be as effective as 5–10% concentrations but with significantly less irritation\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo resistance:\u003c\/strong\u003e Unlike topical antibiotics, bacteria cannot develop resistance to benzoyl peroxide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAAD recommended:\u003c\/strong\u003e Listed as a first-line acne treatment by the American Academy of Dermatology\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eMay bleach hair, fabrics, and colored materials on contact. Can cause dryness and mild peeling, especially in the first weeks.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eGlycerin ~3-5%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA powerful humectant that draws moisture into the skin, helping offset the drying effects of the active ingredients. Maintains the skin's moisture barrier during treatment.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFunction:\u003c\/strong\u003e Skin-identical moisturizing ingredient with comedogenicity rating of 0\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBenefit:\u003c\/strong\u003e Effective from as low as 3%, helps protect against irritation caused by retinoids and benzoyl peroxide\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003ePropylene Glycol ~4%\u003cspan class=\"tag supporting\"\u003eFunctional\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA solvent and humectant that enhances penetration of active ingredients into the skin. Also provides additional moisturizing properties to the gel base.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRole:\u003c\/strong\u003e Improves delivery of adapalene and benzoyl peroxide to skin target sites\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafety:\u003c\/strong\u003e Generally recognized as safe by toxicology experts at concentrations used in cosmetics\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eMay cause skin irritation in individuals with propylene glycol sensitivity. Contains 40mg per gram (4% w\/w).\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-accordion\"\u003e\n\u003cinput type=\"checkbox\" id=\"pp-inci\"\u003e\n\u003clabel for=\"pp-inci\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Full Ingredients (INCI)\u003c\/label\u003e\n\u003cdiv class=\"pp-acc-content\"\u003e\n\u003cp\u003e\u003cstrong\u003e12 ingredients\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eActive: Adapalene (0.1%), Benzoyl Peroxide (2.5%). Inactive: Acrylamide\/Sodium Acryloyldimethyltaurate Copolymer, Docusate Sodium, Edetate Disodium, Glycerin, Isohexadecane, Poloxamer 124, Polysorbate 80, Propylene Glycol, Purified Water, Sorbitan Oleate.\u003c\/p\u003e\n\u003cdiv class=\"free-list\"\u003e\n\u003cstrong\u003eFREE FROM:\u003c\/strong\u003e Fragrances, Parabens, Silicones, Sulfates, Drying Alcohols, Oils, Common Allergens, PEG, Gluten, Coconut Derivatives\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-routine\"\u003e\n\u003cspan class=\"eyebrow\"\u003e04\u003c\/span\u003e\u003ch2\u003eWhere it fits in your routine\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eROUTINE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-routine\"\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eGentle Cleanser\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003ePat Dry\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step current\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eEpiduo Gel\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eWait 5–10 min\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eMoisturizer\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e6\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eSPF (AM only)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cp style=\"text-align:center;color:var(--pp-text-muted);font-size:0.82em;margin-top:12px\"\u003e\n Apply Epiduo in the PM only on clean, dry skin. Use a pea-sized amount per area. Always follow with a non-comedogenic moisturizer and use SPF 30+ sunscreen the next morning.\n\u003c\/p\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-how-to-use\"\u003e\n\u003cspan class=\"eyebrow\"\u003e05\u003c\/span\u003e\u003ch2\u003eHow to use\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eHOW TO USE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-steps\"\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eCleanse\u003c\/h4\u003e\n\u003cp\u003eWash your face with a gentle, non-medicated cleanser (e.g., Cetaphil or CeraVe). Pat skin completely dry with a clean towel.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eApply a Pea-Sized Amount\u003c\/h4\u003e\n\u003cp\u003eUse one pea-sized amount for each area: forehead, each cheek, and chin. Apply as a thin film across the entire affected area, not just individual spots.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eAvoid Sensitive Areas\u003c\/h4\u003e\n\u003cp\u003eKeep away from eyes, lips, nostrils, and any broken, sunburned, or eczema-affected skin. If contact occurs, rinse immediately with warm water.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eMoisturize\u003c\/h4\u003e\n\u003cp\u003eWait 5–10 minutes for Epiduo to absorb, then apply a non-comedogenic moisturizer to counteract dryness and support the skin barrier.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eBuild Tolerance Gradually\u003c\/h4\u003e\n\u003cp\u003eWeek 1: apply every other night. Week 2: apply 3–4 nights. Week 3+: increase to nightly use as tolerated. Reduce frequency if excessive irritation occurs.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-who-is-it-for\"\u003e\n\u003cspan class=\"eyebrow\"\u003e06\u003c\/span\u003e\u003ch2\u003eWho is it for?\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eWHO\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-fit\"\u003e\n\u003cdiv class=\"pp-fit-box yes\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003ePerfect for you if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have mild to moderate acne with blackheads, whiteheads, and inflammatory pimples\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You want a single product that combines retinoid and antibacterial action\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Previous treatments with OTC benzoyl peroxide or adapalene alone were not enough\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You need a long-term antibiotic-free maintenance treatment\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are 9 years or older with a dermatologist prescription\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fit-box no\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003eConsider alternatives if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are pregnant, planning to become pregnant, or breastfeeding without doctor approval\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have fungal acne (malassezia folliculitis) — contains polysorbate 80 and sorbitan oleate\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have very sensitive skin, eczema, or rosacea\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You need immediate results — Epiduo requires 4–12 weeks to show significant improvement\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You cannot commit to daily sunscreen use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-skin-types\"\u003e\n\u003cspan class=\"eyebrow\"\u003e07\u003c\/span\u003e\u003ch2\u003eSkin type compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSKIN TYPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-skin-grid\"\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eOily Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eIdeal match. Benzoyl peroxide helps control excess oil while adapalene regulates sebum production. Gel formula absorbs cleanly without adding shine.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eCombination Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eWorks well on oily zones. Apply to acne-prone areas only and use a richer moisturizer on drier areas to balance the formula's drying effects.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eNormal Skin\u003c\/div\u003e\n\u003cspan class=\"rate good\"\u003eGood\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eEffective for acne treatment. May experience mild dryness in the first few weeks, easily managed with a good moisturizer.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eDry Skin\u003c\/div\u003e\n\u003cspan class=\"rate moderate\"\u003eModerate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eCan cause significant dryness, peeling, and discomfort. Start with every-other-day use and pair with a rich, non-comedogenic moisturizer. Buffer with moisturizer if needed.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eSensitive Skin\u003c\/div\u003e\n\u003cspan class=\"rate moderate\"\u003eModerate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eHigher risk of irritation, redness, and stinging. Introduce very slowly (2x per week), use the \"sandwich method\" with moisturizer, and consult your dermatologist.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eAcne-Prone Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eThis is exactly what Epiduo was designed for. Targets all types of acne lesions — comedonal, papular, and pustular — with clinically proven efficacy.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-results\"\u003e\n\u003cspan class=\"eyebrow\"\u003e08\u003c\/span\u003e\u003ch2\u003eResults timeline\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eMONTH 3–6\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-timeline\"\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeek 1–2\u003c\/span\u003e\n\u003ch4\u003eAdjustment \u0026amp; Initial Purging\u003c\/h4\u003e\n\u003cp\u003eSkin may feel dry, tight, and slightly irritated. Mild redness, peeling, and stinging are normal. Some users experience initial breakouts as existing microcomedones are pushed to the surface.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e80% experience some dryness or peeling\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeek 2–4\u003c\/span\u003e\n\u003ch4\u003ePeak Irritation \u0026amp; Early Improvement\u003c\/h4\u003e\n\u003cp\u003eIrritation peaks around week 1–2 then begins to subside. Early signs of improvement become visible — fewer new pimples forming, existing lesions starting to flatten. Skin starts adapting to the retinoid.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e60% notice fewer new breakouts\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eMonth 2–3\u003c\/span\u003e\n\u003ch4\u003eSignificant Clearing\u003c\/h4\u003e\n\u003cp\u003eClinical studies show meaningful reduction in both inflammatory and non-inflammatory lesions by week 8–12. Skin texture improves noticeably. Purging should be fully resolved.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e65% see significant improvement\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eMonth 3–6\u003c\/span\u003e\n\u003ch4\u003eOptimal Results \u0026amp; Maintenance\u003c\/h4\u003e\n\u003cp\u003eMaximum efficacy reached. Skin appears clearer, smoother, and more even-toned. Post-inflammatory marks begin to fade. Most users report dramatically fewer breakouts. Continue use for maintenance.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e80% achieve clear or almost clear skin\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-reviews\"\u003e\n\u003cspan class=\"eyebrow\"\u003e09\u003c\/span\u003e\u003ch2\u003eRatings by platform\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e1K+ REVIEWS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-reviews\"\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eDrugs.com\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 7.3\/10\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e728+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Severe initial purging and dryness in the first 1–3 months before results appear\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eWebMD\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.0\/5\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e500+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Intense redness, burning sensation, and skin peeling during the first few weeks\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eDr Fox Pharmacy\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.76\/5\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e29+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Skin conditioning period requires patience; can be uncomfortable initially\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eE-Surgery\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.79\/5\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e364+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Can make skin very dry; users advise pairing with a strong moisturizer\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-pros-cons\"\u003e\n\u003cspan class=\"eyebrow\"\u003e10\u003c\/span\u003e\u003ch2\u003ePros \u0026amp; cons\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eBALANCED\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-proscons\"\u003e\n\u003cdiv class=\"pp-pc pros\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003ePraised\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Clinically proven dual-action formula tackling both bacteria and clogged pores\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Antibiotic-free — safe for long-term maintenance without resistance risk\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Once-daily evening application — simple routine\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Significantly reduces both inflammatory and non-inflammatory acne lesions\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Also improves skin texture, tone, and reduces appearance of fine lines\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fragrance-free, paraben-free, oil-free, silicone-free formula\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Approved for ages 9+ with extensive clinical trial data\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Many users report life-changing results after 3–4 months\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-pc cons\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eCriticized\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Harsh initial purging period (1–3 months) that discourages many users\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Significant dryness, peeling, redness, and stinging in first weeks\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Requires prescription — not available over the counter\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Expensive without insurance (list price around $200–$400 USD)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Bleaches fabrics, pillowcases, towels, and clothing\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Increases sun sensitivity — strict sunscreen use required\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Not safe during pregnancy (contains retinoid)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Not suitable for fungal acne\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-dupes\"\u003e\n\u003cspan class=\"eyebrow\"\u003e11\u003c\/span\u003e\u003ch2\u003eBudget-friendly alternatives (dupes)\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eDUPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-dupes\"\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match high\"\u003e85% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/adapalene-benzoyl-peroxide-topical-gel\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/w31bbv2rz0u2vxbw6l8jwy79tzi9_square_f1aab9a8-2ec9-48b9-807b-c8a094699ad1.png?v=1776898460\" alt=\"Adapalene\/Benzoyl Peroxide Topical Gel\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/adapalene-benzoyl-peroxide-topical-gel\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003eDifferin Gel 0.1% (Adapalene) + OTC Benzoyl Peroxide 2.5%\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e$13–$20\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eBudget Pick\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eUsing OTC Differin gel (adapalene 0.1%) together with a separate benzoyl peroxide product replicates the same two active ingredients. Requires applying two products instead of one, but saves significant money. No prescription needed for Differin 0.1%.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e70% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/adapalene-benzoyl-peroxide-topical-gel\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/w31bbv2rz0u2vxbw6l8jwy79tzi9_square_f1aab9a8-2ec9-48b9-807b-c8a094699ad1.png?v=1776898460\" alt=\"Adapalene\/Benzoyl Peroxide Topical Gel\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/adapalene-benzoyl-peroxide-topical-gel\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003eGeneric Adapalene\/Benzoyl Peroxide Gel 0.1%\/2.5%\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e$40–$80\u003c\/div\u003e\n\u003cdiv class=\"tag similar\"\u003eSame Formula\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eThe exact same active ingredients and concentrations in generic form. Identical efficacy at a fraction of the brand-name price. Still requires a prescription. Check with your pharmacy for availability.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e60% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"photo-fallback\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003eAcnecide 5% Benzoyl Peroxide Gel + The Ordinary Retinol 0.5%\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e$15–$20\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eBudget Pick\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eA budget OTC combination pairing benzoyl peroxide with retinol instead of adapalene. Less potent retinoid action and should be used on alternate nights to avoid irritation. Good entry-level option for mild acne.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-compare\"\u003e\n\u003cspan class=\"eyebrow\"\u003e12\u003c\/span\u003e\u003ch2\u003eComparison with competitors\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSIDE-BY-SIDE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-compare\"\u003e\n\u003cdiv class=\"pp-compare-card featured\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/epiduo-gel-0-1-2-5\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/3conrn2hzv50y4qn1j93c2qz6max.jpg?v=1767009851\" alt=\"Epiduo Gel 0.1%\/2.5%\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/epiduo-gel-0-1-2-5\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003eEpiduo Gel 0.1%\/2.5% (Galderma)\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredients\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eAdapalene 0.1% + BP 2.5%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eType\u003c\/span\u003e\n\u003cspan class=\"value\"\u003ePrescription Gel\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eLong-Term Use\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes — no resistance\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eApplication\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eOnce daily (PM)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePregnancy Safe\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-gel-1\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/jhqxo8fx1shmbe0n3naznvyidmkb.jpg?v=1775834408\" alt=\"Clindamycin Gel 1%\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/clindamycin-gel-1\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003eDuac Gel (Clindamycin + BP)\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredients\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eClindamycin 1% + BP 3–5%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eType\u003c\/span\u003e\n\u003cspan class=\"value\"\u003ePrescription Gel\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo — contains antibiotic\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eLong-Term Use\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo — max 12 weeks\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eApplication\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eOnce daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePregnancy Safe\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/adapalene-gel-0-4\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/ej9756kxs6kxq05n0gylazqmvnh4_square_1ee2130f-844d-4aef-b967-cc76168634de.png?v=1776769397\" alt=\"Adapalene Gel 0.1%\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/adapalene-gel-0-4\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003eDifferin Gel 0.1% (Adapalene)\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredients\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eAdapalene 0.1% only\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eType\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eOTC (no prescription)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eLong-Term Use\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eApplication\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eOnce daily (PM)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePregnancy Safe\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/finacea-15-azelaic-acid-gel\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/lv1sf9f41ixhqpyz5k7kweyvlcfn_square.png?v=1775746012\" alt=\"Finacea 15% Azelaic Acid Gel\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/finacea-15-azelaic-acid-gel\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003eFinacea Gel (Azelaic Acid 15%)\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredients\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eAzelaic Acid 15%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eType\u003c\/span\u003e\n\u003cspan class=\"value\"\u003ePrescription Gel\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eLong-Term Use\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eApplication\u003c\/span\u003e\n\u003cspan class=\"value\"\u003eTwice daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003ePregnancy Safe\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes (Category B)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-storage\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eStorage \u0026amp; shelf life\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e3 MONTHS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePeriod After Opening (PAO)\u003c\/strong\u003e\n\u003cp\u003e3 months after opening (for Epiduo Forte; standard Epiduo should be used before expiry date on packaging). Check expiry date printed on tube.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eStorage\u003c\/strong\u003e\n\u003cp\u003eStore at room temperature 20–25°C (68–77°F). Protect from light and heat. Keep tube tightly closed. Do not refrigerate.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePackaging\u003c\/strong\u003e\n\u003cp\u003eWhite plastic tube with screw cap (45g, 60g) or white pump with snap-on cap (45g). Opaque packaging protects light-sensitive ingredients.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-package\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTravel Friendly\u003c\/strong\u003e\n\u003cp\u003eYes — 45g tube is under 100ml\/3.4oz TSA limit. Keep away from heat during travel and store in a toiletry bag away from direct sunlight.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-faq\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eFAQ\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq1\"\u003e\n\u003clabel for=\"faq1\"\u003eIs Epiduo Gel pregnancy and breastfeeding safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eNo, Epiduo is not safe during pregnancy. It contains adapalene, a retinoid, and all retinoids are contraindicated in pregnancy due to the potential risk of birth defects. If you become pregnant while using Epiduo, discontinue immediately and consult your doctor. For breastfeeding, the European SmPC states that Epiduo can be used during breastfeeding since systemic exposure is negligible, but you should avoid applying it to the chest area. Always consult your healthcare provider for personalized guidance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq2\"\u003e\n\u003clabel for=\"faq2\"\u003eIs Epiduo Gel fungal acne (malassezia) safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eNo, Epiduo is not considered fungal acne safe. The formula contains polysorbate 80 and sorbitan oleate, which are known triggers for malassezia (fungal acne). Sorbitan oleate in particular has a medium comedogenicity risk for fungal acne. If you have malassezia folliculitis, consider alternatives like azelaic acid (Finacea) or pure benzoyl peroxide wash formulations without these emulsifiers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq3\"\u003e\n\u003clabel for=\"faq3\"\u003eCan I use Epiduo Gel with retinol, vitamin C, AHA, or BHA?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eUse extreme caution when combining Epiduo with other active ingredients. Avoid using additional retinoids (retinol, tretinoin) as this can cause severe irritation. Avoid AHAs (glycolic acid, lactic acid) and BHAs (salicylic acid) on the same night as Epiduo, as the cumulative exfoliating effects can damage your skin barrier. Vitamin C (L-ascorbic acid) is best used in the AM while Epiduo stays in your PM routine. Always introduce new actives gradually and consult your dermatologist before combining treatments.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq4\"\u003e\n\u003clabel for=\"faq4\"\u003eWhat skin type is Epiduo Gel best for?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eEpiduo works best for oily, combination, and acne-prone skin types. The gel formula absorbs cleanly and helps control excess oil production. It can also be used on normal skin with appropriate moisturizer support. Dry and sensitive skin types may find Epiduo too drying and irritating — these users should introduce the product very slowly (2x per week) and use the \"sandwich method\" (moisturizer-Epiduo-moisturizer) to buffer irritation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq5\"\u003e\n\u003clabel for=\"faq5\"\u003eHow long until I see results from Epiduo Gel?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eEarly signs of improvement typically appear within 1–4 weeks of consistent use. However, the full benefits may take 8–12 weeks. Many users report a \"purging\" phase in weeks 1–4 where acne temporarily worsens before it improves. Clinical trials show significant lesion reduction by week 12, with optimal results at 3–6 months. The key is persistence — do not stop using Epiduo during the purging phase unless advised by your dermatologist.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq6\"\u003e\n\u003clabel for=\"faq6\"\u003eWhere does Epiduo Gel go in my skincare routine?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eApply Epiduo in the evening only, after cleansing and drying your face completely. It goes on clean, dry skin as the treatment step before moisturizer. The routine order is: gentle cleanser, pat dry, Epiduo (pea-sized amounts), wait 5–10 minutes, then non-comedogenic moisturizer. In the morning, use a gentle cleanser, moisturizer, and broad-spectrum SPF 30+ sunscreen. Do not apply any other medicated products at the same time as Epiduo unless directed by your doctor.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq7\"\u003e\n\u003clabel for=\"faq7\"\u003eIs Epiduo Gel comedogenic \/ will it clog pores?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eEpiduo has a low comedogenic rating of 1\/5. The gel is formulated with a water-based vehicle and is free from oils, silicones, and heavy emollients. It is specifically designed to unclog pores rather than block them. However, it does contain sorbitan oleate, which has medium comedogenicity for fungal acne specifically. For traditional comedonal acne, Epiduo actively helps clear and prevent clogged pores.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq8\"\u003e\n\u003clabel for=\"faq8\"\u003eHow long does Epiduo Gel last after opening?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eEpiduo Forte has a labeled shelf life of 3 months after opening. Standard Epiduo should be used before the expiration date printed on the tube or carton. Store at room temperature (20–25°C \/ 68–77°F), keep the tube tightly closed, and protect it from light and heat. Do not use if the gel has changed color, texture, or consistency. One 45g tube typically lasts 1–3 months with regular once-daily use on the face.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-verdict\"\u003e\n    \u003cdiv class=\"eyebrow\"\u003e— Skincarisma verdict\u003c\/div\u003e\n    \u003cdiv class=\"score-row\"\u003e\n      \u003cspan class=\"score\"\u003e4.3\u003c\/span\u003e\n      \u003cspan class=\"max\"\u003e\/ 5\u003c\/span\u003e\n      \u003cspan class=\"stars\"\u003e★★★★☆\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"text\"\u003e\n\u003cstrong\u003eVerdict:\u003c\/strong\u003e Epiduo Gel 0.1%\/2.5% by Galderma is one of the most effective prescription topical acne treatments available, combining the gold-standard ingredients adapalene and benzoyl peroxide into a single, once-daily gel. It excels at treating both comedonal and inflammatory acne without contributing to antibiotic resistance, making it suitable for long-term use. The initial purging and irritation phase (1–3 months) is the biggest hurdle, but users who push through consistently report dramatic, lasting improvements. Not recommended for pregnancy, fungal acne, or those unable to tolerate retinoid-level irritation. For mild to moderate acne sufferers who can commit to the adjustment period and daily sunscreen, Epiduo remains a dermatologist-trusted powerhouse.\n\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003cbutton class=\"pp-back-to-top\" aria-label=\"Back to top\" type=\"button\" style=\"position:fixed;bottom:24px;right:24px;width:44px;height:44px;border-radius:50%;background:var(--pp-accent);color:#fff;border:none;display:none;cursor:pointer;z-index:50;box-shadow:0 4px 16px rgba(13,31,45,0.2)\"\u003e↑\u003c\/button\u003e\n  \u003cscript\u003e\n  (function () {\n    var btt = document.querySelector('.pp-back-to-top');\n    if (!btt) return;\n    var ticking = false;\n    function onScroll () {\n      if (!ticking) {\n        requestAnimationFrame(function () {\n          btt.style.display = window.scrollY \u003e 600 ? 'block' : 'none';\n          ticking = false;\n        });\n        ticking = true;\n      }\n    }\n    window.addEventListener('scroll', onScroll, { passive: true });\n    btt.addEventListener('click', function () { window.scrollTo({ top: 0, behavior: 'smooth' }); });\n  })();\n  \u003c\/script\u003e\n\u003c\/div\u003e\n","brand":"Galderma","offers":[{"title":"Default Title","offer_id":52118369206615,"sku":null,"price":4100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/3conrn2hzv50y4qn1j93c2qz6max.jpg?v=1767009851","url":"https:\/\/www.skincarisma.com\/products\/epiduo-gel-0-1-2-5","provider":"Skincarisma","version":"1.0","type":"link"}