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Serum

Serum

Product Description

Product overview

Made in Various INTERNATIONAL

Latisse is the first and only FDA-approved prescription treatment for eyelash hypotrichosis. Powered by bimatoprost 0.03%, this clinical-strength serum extends the growth phase of eyelash follicles to deliver visibly longer, fuller, and darker lashes in as little as 4 weeks, with full results at 16 weeks.

FDA-Approved Clinically Proven Prescription Only Prostaglandin Analog Fragrance-Free Paraben-Free Oil-Free Silicone-Free
Pregnancy
No
Fungal Acne
Yes
Comedogenic
0/5
Type
Rx Serum
Active
Bimatoprost 0.03%
Size
3 mL / 5 mL
Price
$120–$212
Brand
Allergan (AbbVie)
Real reviews · YouTube Shorts
Why it's different

FDA-Approved Formula

The only prescription eyelash treatment approved by the FDA for growing longer, fuller, and darker lashes. Backed by rigorous clinical trials.

01

Texture & feel

SENSORY
Consistency
Clear liquid
Scent
Fragrance-free
Absorption
Instant
Finish
Invisible

FDA-Approved Formula

The only prescription eyelash treatment approved by the FDA for growing longer, fuller, and darker lashes. Backed by rigorous clinical trials.

Clinically Proven Results

76% of clinical trial participants saw significant lash improvement at 16 weeks, with visible changes starting as early as 4 weeks.

Prostaglandin Analog Technology

Bimatoprost extends the anagen (growth) phase of eyelash follicles, increasing the number of hairs produced and their length and darkness.

Minimal, Clean Formula

Only 6 ingredients total. Free from fragrances, oils, parabens, silicones, and sulfates. Sterile ophthalmic-grade solution.

02

Safety & compatibility

SAFE
Pregnancy: Not Safe

Bimatoprost is classified as FDA Pregnancy Category C. Animal studies showed adverse effects. Do not use during pregnancy.

Breastfeeding: Caution

Unknown whether bimatoprost passes into breast milk. Consult your doctor before using while breastfeeding.

Fungal Acne (Malassezia) Safe

Contains no ferments, fatty acids, esters, or polysorbates. Only 6 clean, simple ingredients.

Non-Comedogenic

Applied only to the upper lash line, not across facial skin. Oil-free, water-based sterile solution rated 0/5 comedogenic.

Iris Pigmentation Risk

May cause permanent brown darkening of the iris (colored part of the eye), especially in hazel or green eyes.

Eyelid Skin Darkening

May cause reversible darkening of the eyelid skin. Generally resolves after discontinuing use.

Contact Lens Users

Remove contact lenses before application. Wait at least 15 minutes before reinserting. May discolor soft lenses.

Prescription Required

Latisse is available only with a doctor's prescription. Do not share with others or use if allergic to any ingredient.

03

Ingredient breakdown

INGREDIENTS

Bimatoprost 0.03%Proven

A synthetic prostaglandin analog and the sole active ingredient. Originally developed to treat glaucoma (as Lumigan), bimatoprost was FDA-approved for eyelash hypotrichosis in 2008 after patients noticed dramatic lash growth as a side effect.

  • Mechanism: Extends the anagen (active growth) phase of eyelash hair follicles, increasing length, thickness, and melanin production
  • Clinical trial: 76% of participants showed significant improvement in overall eyelash prominence at 16 weeks (GEA scale)
  • Onset: Visible results in 4–8 weeks; full results at 16 weeks with consistent nightly use
May cause iris darkening (potentially permanent), eyelid hyperpigmentation (reversible), eye redness, itching, and in rare cases periorbital fat loss with prolonged use.

Benzalkonium Chloride 0.005%Preservative

A quaternary ammonium compound used as a preservative to maintain the sterility of the ophthalmic solution and prevent microbial contamination.

  • Function: Antimicrobial preservative commonly used in eye drops and ophthalmic solutions
  • Concentration: Present at 0.05 mg/mL — a standard safe level for ophthalmic use
Can discolor soft contact lenses. Remove lenses before application and wait 15 minutes before reinserting.

Sodium ChlorideStabilizer

Common salt used to make the solution isotonic — matching the osmotic pressure of natural tears so it does not sting or irritate the delicate eye area upon application.

  • Function: Maintains osmotic balance for comfort and safety on application

Sodium Phosphate Dibasic & Citric AcidBuffer System

These two ingredients work together as a pH buffer system, maintaining the solution's pH between 6.8–7.8 throughout its shelf life. This ensures stability, efficacy, and comfortable application.

  • Function: pH stabilization within a safe range for ophthalmic use
  • pH Range: 6.8–7.8 (close to natural tear pH of ~7.4)

6 ingredients

Active: Bimatoprost 0.3 mg/mL. Preservative: Benzalkonium Chloride 0.05 mg/mL. Inactives: Sodium Chloride, Sodium Phosphate Dibasic, Citric Acid, Purified Water. Sodium Hydroxide and/or Hydrochloric Acid (pH adjuster).

FREE FROM: Fragrances, Parabens, Sulfates, Silicones, Oils, Alcohols, Dyes, Phthalates, Formaldehyde, Mineral Oil, Petrolatum
04

Where it fits in your routine

ROUTINE
1
Makeup Removal
2
Cleanser
3
Latisse
4
Eye Cream
5
Moisturizer

Apply once nightly after cleansing face and removing contacts. Use before any other eye area products. Wait 15 minutes before reinserting contact lenses.

05

How to use

HOW TO USE
1

Cleanse & Prep

Wash your face, remove all makeup, and take out contact lenses. Pat the eye area dry.

2

Prepare Applicator

Remove one sterile applicator from its tray. Place one drop of Latisse on the applicator tip — do not apply directly from the bottle.

3

Apply to Upper Lash Line

Carefully brush the applicator along the skin at the base of the upper eyelashes, from the inner to the outer corner. The lash line should feel lightly moist.

4

Blot Excess

Use a tissue to blot any excess solution beyond the eyelid margin. Do NOT apply to the lower eyelid or directly into the eye.

5

Repeat & Dispose

Discard the used applicator. Use a new sterile applicator for the other eye. Each applicator is single-use only.

06

Who is it for?

WHO

Perfect for you if:

  • You have naturally thin, sparse, or short eyelashes (hypotrichosis)
  • Your lashes have thinned due to aging, hormonal changes, or medical treatments
  • You want a clinically proven, FDA-approved lash growth treatment
  • You are committed to nightly application for at least 16 weeks
  • You want to reduce reliance on extensions, falsies, or heavy mascara
  • You are not pregnant, breastfeeding, or allergic to bimatoprost

Consider alternatives if:

  • You are pregnant, planning to become pregnant, or breastfeeding
  • You have glaucoma or use IOP-lowering prostaglandin eye drops
  • You are concerned about potential iris color change (especially with light eyes)
  • You want a non-prescription, over-the-counter option
  • You are unwilling to commit to consistent nightly application
  • You have active eye infections, uveitis, or macular edema
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Oil-free, water-based solution. Applied only to lash line — no impact on facial oiliness or pore congestion.

Dry Skin
Excellent

Does not strip moisture or cause dryness. Targeted lash-line application means it won't affect overall skin hydration.

Combination
Excellent

Lightweight liquid formula works well across all skin zones. No interference with other skincare products.

Sensitive Skin
Moderate

May cause eye redness, itching, or eyelid irritation in sensitive individuals. Contains preservative benzalkonium chloride. Patch test strongly recommended.

Acne-Prone
Excellent

Non-comedogenic (0/5). Oil-free, fungal-acne safe. No ingredients that clog pores or trigger breakouts.

08

Results timeline

WEEK 16
Week 1–2

Adjustment Period

Lashes may feel slightly different. Some users report mild eye redness or itching as the eye area adjusts. No visible lash growth yet.

10% noticed early signs
Week 4

First Visible Changes

Early lash growth becomes noticeable. Lashes may appear slightly longer and some new fine lashes start emerging at the base.

25% noticed improvement
Week 8

Significant Growth

Clear increase in lash length and density. Statistically significant differences documented in clinical trials at this point. Lashes begin to look darker.

50% noticed significant change
Week 16

Full Results

Peak results achieved — lashes are measurably longer, thicker, and darker. This is the primary endpoint from FDA clinical trials. Maintenance usage can begin (3–4x per week).

76% achieved significant lash prominence
09

Ratings by platform

330+ REVIEWS
Drugs.com
9.0/10
Rating
5+
Reviews
Main complaint: Lashes return to baseline after stopping use
WebMD
3.5/5
Rating
72+
Reviews
Main complaint: Eye irritation, eyelid darkening, and high cost
RealSelf
74%
Worth It
153+
Reviews
Main complaint: Orbital fat loss and hollowed appearance around eyes with prolonged use
Influenster
4.5/5
Rating
100+
Reviews
Main complaint: Expensive and requires ongoing use to maintain results
10

Pros & cons

BALANCED

Praised

  • Only FDA-approved treatment for eyelash growth — gold standard
  • Clinically proven with 76% success rate at 16 weeks
  • Ultra-clean formula with only 6 ingredients
  • Dramatic visible results — longer, fuller, darker lashes
  • Simple once-daily evening application
  • Can reduce need for mascara, extensions, and falsies
  • Fragrance-free, oil-free, non-comedogenic

Criticized

  • Expensive — $120–$212 per bottle (1–2 month supply)
  • Requires ongoing use; results reverse when discontinued
  • Risk of permanent iris color change (darkening)
  • Eyelid skin darkening (hyperpigmentation) in some users
  • Possible periorbital fat loss with prolonged use
  • Prescription required — not available over the counter
  • Excessive single-use plastic applicators create waste
  • Not safe during pregnancy or while breastfeeding
11

Budget-friendly alternatives (dupes)

DUPES
95% Match
Generic Bimatoprost 0.03% (via GoodRx)
$57.94
Budget Pick

Identical active ingredient (bimatoprost 0.03%) at a fraction of the price. Same prescription requirement but significantly cheaper with coupons. Exact same mechanism and efficacy.

65% Match
GrandeLASH-MD Lash Enhancing Serum
$68.00
OTC Alternative

Uses isopropyl cloprostenate (a milder prostaglandin analog) plus peptides and vitamins. No prescription needed. Results are slower and less dramatic, but fewer side effects. 3-month supply.

60% Match
Advanced Eyelash Conditioner & Serum
$98.00

Contains a proprietary BioPeptin complex with latanoprost analog, biotin, peptides, and botanical extracts. No prescription required. Gentler formula with reduced side effect risk but milder results.

12

Comparison with competitors

SIDE-BY-SIDE

GrandeLASH-MD

Active Ingredient Isopropyl Cloprostenate
FDA Approved No
Prescription Not Required
Full Results 4–6 weeks (visible) / 3 months (full)
Clinical Evidence Limited (consumer studies)
Side Effect Risk Low–Moderate
Supply Duration 3 months

RevitaLash Advanced

Active Ingredient BioPeptin Complex + Latanoprost Analog
FDA Approved No
Prescription Not Required
Full Results 6 weeks (visible) / 3 months (full)
Clinical Evidence Moderate (brand studies)
Side Effect Risk Low
Supply Duration 2–3 months

Vegamour GRO Lash Serum

Active Ingredient Plant Peptides + Red Clover
FDA Approved No
Prescription Not Required
Full Results 90 days+
Clinical Evidence Limited
Side Effect Risk Very Low
Supply Duration 1 month
13

Storage & shelf life

1 MONTHS
Period After Opening (PAO)

Use within the period indicated on packaging. Typically a 3mL bottle lasts ~1 month and a 5mL bottle ~2 months when used as directed.

Storage

Store at 2°C to 25°C (36°F to 77°F). Keep the bottle tightly closed when not in use. Can be stored at room temperature or refrigerated.

Packaging

Opaque white LDPE dropper bottle with sterile disposable applicators (70 with 3mL, 140 with 5mL). Tamper-evident seal.

Travel Friendly

Yes — both 3mL and 5mL bottles are well under the 100mL TSA liquid limit. Compact size fits easily in a toiletry bag.

13

Frequently asked questions

FAQ

No. Latisse is not considered safe during pregnancy. Bimatoprost was classified as FDA Pregnancy Category C, meaning animal studies showed adverse reproductive effects (including increased miscarriage risk and reduced fetal weight), though human data is limited. Most dermatologists and OB-GYNs advise discontinuing Latisse during pregnancy. For breastfeeding, safety is uncertain — it is unknown whether bimatoprost passes into breast milk. Consult your doctor before using while nursing.

Yes. Latisse is fungal acne safe. Its formula contains only 6 ingredients, none of which are ferments, fatty acids, esters, or polysorbates that feed malassezia yeast. Additionally, it is applied only to the thin skin of the upper eyelid margin, not across broader facial areas where fungal acne typically occurs.

Yes, Latisse can generally be used alongside retinol, vitamin C, AHAs, and BHAs since it is applied specifically to the lash line and not the broader facial area. However, avoid applying active serums directly onto the eyelid margin where Latisse has been applied, as this could increase irritation. Wait until Latisse has fully absorbed (a few minutes) before applying other products nearby. If you experience increased sensitivity or redness, space out your applications.

Latisse works across all skin types since it targets the eyelash follicles rather than the facial skin. It is oil-free, non-comedogenic, and fragrance-free, making it suitable for oily, dry, combination, and acne-prone skin. Those with sensitive skin or conditions like rosacea around the eyes should use caution, as bimatoprost can cause eye redness and eyelid irritation in some individuals.

Most users begin noticing initial changes at 4 weeks, with clearly visible improvement by 8 weeks. Full, peak results are achieved at 16 weeks (4 months) of consistent nightly use, as documented in FDA clinical trials. After reaching full results, many doctors recommend reducing to maintenance application of 3–4 times per week. Results gradually reverse if you stop using Latisse entirely.

Apply Latisse at night after removing all makeup, cleansing your face, and removing contact lenses. It should be the first product applied to the eye area. After application and absorption, you can proceed with your regular nighttime routine (eye cream, serum, moisturizer). Wait at least 15 minutes before reinserting contact lenses.

No. Latisse has a comedogenic rating of 0/5. It is an oil-free, water-based sterile ophthalmic solution with only 6 ingredients. It is applied in a tiny amount specifically to the upper lash line, not across the face. There is no risk of pore clogging or acne breakouts from Latisse when used as directed.

A 3mL bottle of Latisse is designed to last approximately 1 month (30 days) with nightly use on both eyes using the provided sterile applicators. A 5mL bottle lasts approximately 2 months (70 days). Some users report stretching the supply longer by using alternative application methods, though this is off-label. Store at 2–25°C (36–77°F) and keep the bottle tightly sealed. Do not use beyond the expiration date printed on the packaging.

— Skincarisma verdict
4.0 / 5 ★★★★☆

Verdict: Latisse remains the undisputed gold standard for eyelash growth — it is the only FDA-approved prescription treatment with robust clinical evidence proving it makes lashes longer, fuller, and darker. The ultra-minimal 6-ingredient formula is impressively clean, and the results are genuinely dramatic for most users. However, the high cost ($120–$212/month), requirement for ongoing use to maintain results, and meaningful side effect risks (iris darkening, eyelid hyperpigmentation, periorbital fat loss) hold it back from a perfect score. Best suited for those with genuine hypotrichosis or significant lash thinning who want the strongest, most scientifically proven option available and are comfortable with the potential risks under medical supervision.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 1 ingredient(s):
Citric Acid
brightening Brightening from 1 ingredient(s):
Citric Acid
wound Promotes Wound Healing from 1 ingredient(s):
Citric Acid
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
66% 33%

Product ingredient list

Showing first 5 of 6 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
0 Unknown
Benzalkonium Chloride
Antimicrobial, Preservative
1 Unknown
Sodium Chloride
Masking, Viscosity Controlling, Bulking Agent
1 B
Sodium Phosphate
Buffering Agent
2 A
Citric Acid
Masking, Fragrance, Chelating Agent, Ph Adjuster, Buffering Agent
brightening Brightening
anti-aging Anti-Aging
Promotes Wound Healing
Texture
Pores
1 Unknown
Water
Solvent, Skin Conditioning
VIEW ALL INGREDIENTS