{"product_id":"soolantra","title":"Soolantra","description":"\u003cdiv class=\"pp\" lang=\"en\" itemscope itemtype=\"https:\/\/schema.org\/Product\"\u003e\n  \u003cmeta itemprop=\"name\" content=\"Galderma Soolantra\"\u003e\n  \u003cmeta itemprop=\"brand\" content=\"Galderma\"\u003e\n  \u003cmeta itemprop=\"category\" content=\"Skincare \u0026gt; Prescription\"\u003e\n  \u003cmeta itemprop=\"countryOfOrigin\" content=\"Various\"\u003e\n\n  \u003cscript type=\"application\/ld+json\"\u003e{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"FAQPage\",\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Soolantra pregnancy and breastfeeding safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No. Soolantra is not recommended during pregnancy or breastfeeding. Although topical absorption is low, animal studies at high oral doses have shown embryofetal toxicity, and it is not known whether ivermectin passes into breast milk. It was previously classified as FDA pregnancy category C. If you are pregnant, planning pregnancy, or nursing, speak with your dermatologist about alternatives such as azelaic acid, which has a more favorable pregnancy profile.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Soolantra fungal acne (malassezia) safe?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No. Soolantra contains several ingredients that can feed Malassezia yeast, including oleyl alcohol, isopropyl palmitate, cetyl alcohol, and stearyl alcohol. If you have fungal acne (pityrosporum folliculitis), these ingredients may worsen your condition. However, if your breakouts are truly papulopustular rosacea (Demodex-driven), the antiparasitic action of ivermectin typically outweighs the fungal-acne concern. A dermatologist can help distinguish the two.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can I use Soolantra with retinol, vitamin C, AHA, or BHA?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"With caution. Combining Soolantra with strong actives can significantly increase irritation, especially during the first few weeks. A common approach is to use Soolantra at night and a gentle vitamin C in the morning, or to alternate nights with retinol once your skin has adjusted (typically after week 4-6). Avoid AHA\/BHA exfoliants during the purge phase. Always wait at least 20-30 minutes between products and prioritize barrier-supportive moisturizers.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What skin type is Soolantra best for?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Soolantra is best for adults with papulopustular rosacea — characterized by persistent redness combined with acne-like bumps and pustules on the central face. It is excellent for sensitive, dry, and combination skin types with rosacea. It is less ideal for fungal-acne-prone skin or for people whose primary concern is diffuse flushing or visible blood vessels (erythematotelangiectatic rosacea), for which Mirvaso, Rhofade, or laser therapy may be more appropriate.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long until I see results from Soolantra?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"In Phase 3 clinical trials, statistically significant improvement was observed as early as week 2. Most users see clear progress by weeks 4-6, with full results at 12-16 weeks of daily use. Be prepared for an initial purge (worsening) in the first 1-2 weeks as Demodex mites die off and release bacterial content — this is normal and expected. Push through: the majority of users who persist achieve 70-90% lesion clearance by week 12.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Where does Soolantra go in my skincare routine?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Apply Soolantra to completely clean, dry skin as the first leave-on product — after cleansing, before moisturizer. Use a pea-sized amount per affected zone (forehead, chin, nose, each cheek) and spread in a thin layer. Wait 15-20 minutes for the cream to absorb and reach the follicle, then apply your moisturizer. In the morning, always finish with a mineral-based SPF, as rosacea skin is highly sun-sensitive.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is Soolantra comedogenic \/ will it clog pores?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Mildly comedogenic — rated approximately 3\/5. The formula contains isopropyl palmitate (4\/5) and fatty alcohols (2\/5) that can contribute to pore-clogging in very acne-prone skin. However, for its target audience (rosacea sufferers), the anti-inflammatory and antiparasitic benefits far outweigh the comedogenic concern. If you have combination acne-rosacea, monitor for comedonal breakouts and consider pairing with a non-comedogenic moisturizer.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How long does Soolantra last after opening?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Soolantra has an unopened shelf life of 24 months when stored between 20-25°C (68-77°F). Once opened, it should generally be used within 6-12 months, though the FDA-approved prescribing information does not specify a separate post-opening expiry. Always check the printed expiration date on the tube, avoid extreme heat, do not freeze, and discard if the cream changes color, texture, or odor.\"\n          }\n        }\n      ]\n    },\n    {\n      \"@type\": \"HowTo\",\n      \"name\": \"How to use Galderma Soolantra\",\n      \"totalTime\": \"PT2M\",\n      \"step\": [\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 1,\n          \"name\": \"Cleanse Gently\",\n          \"text\": \"Wash your face with a mild, non-foaming cleanser. Pat completely dry — applying to damp skin increases irritation.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 2,\n          \"name\": \"Take a Pea-Sized Amount\",\n          \"text\": \"Dispense a pea-sized amount for each affected area: forehead, chin, nose, and each cheek. Five peas maximum per full-face application.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 3,\n          \"name\": \"Apply a Thin Layer\",\n          \"text\": \"Spread evenly in a thin layer over the affected zones. Avoid lips, eyes, and inside the nostrils.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 4,\n          \"name\": \"Wash Your Hands\",\n          \"text\": \"Wash your hands thoroughly after application to avoid transferring the cream to eyes or mucous membranes.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 5,\n          \"name\": \"Wait, Then Moisturize\",\n          \"text\": \"Allow 15-20 minutes for absorption, then follow with a gentle, barrier-supportive moisturizer.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 6,\n          \"name\": \"Use Consistently for 12 Weeks\",\n          \"text\": \"Apply once daily (typically at night). Continue for the full treatment course — courses can be repeated if needed.\"\n        }\n      ]\n    },\n    {\n      \"@type\": \"ItemList\",\n      \"name\": \"Galderma Soolantra — Ingredients (INCI)\",\n      \"numberOfItems\": 18,\n      \"itemListElement\": [\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 1,\n          \"name\": \"Ivermectin 1% (Active)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 2,\n          \"name\": \"Water (Purified)\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 3,\n          \"name\": \"Glycerin\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 4,\n          \"name\": \"Isopropyl Palmitate\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 5,\n          \"name\": \"Carbomer Copolymer Type B\"\n        },\n        {\n          \"@type\": \"ListItem\",\n          \"position\": 6,\n   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class=\"dot\"\u003e\u003c\/span\u003e\n      \u003cspan class=\"tag\"\u003eINTERNATIONAL\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"pp-subtitle\"\u003eSoolantra by Galderma is an FDA-approved prescription cream containing 1% ivermectin, clinically proven to reduce the inflammatory bumps, pustules, and redness of papulopustular rosacea. Its dual antiparasitic and anti-inflammatory action targets Demodex mites and calms irritated skin in as little as two weeks.\u003c\/p\u003e\n    \u003cdiv class=\"pp-badges\"\u003e\n\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e FDA-Approved\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e 1% Ivermectin\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Once-Daily Use\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Antibiotic-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fragrance-Free\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Dermatologist Prescribed\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Clinically Proven\u003c\/span\u003e\u003cspan class=\"pp-badge\"\u003e\u003csvg class=\"check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Rosacea Specialist\u003c\/span\u003e\n\u003c\/div\u003e\n    \u003cnav class=\"pp-nav\" aria-label=\"Jump to product section\"\u003e\n      \u003cdiv class=\"pp-nav-head\"\u003eJump to section\u003c\/div\u003e\n      \u003cdiv class=\"pp-nav-list\"\u003e\n        \u003ca href=\"#pp-safety\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSafety\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-ingredients\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eIngredients\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-routine\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-refresh\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eRoutine\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-how-to-use\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eHow to use\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-skin-types\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eSkin types\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-results\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-trending\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eResults\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-reviews\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-star\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eReviews\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-dupes\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-coin\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eDupes\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n        \u003ca href=\"#pp-faq\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-help\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003cspan class=\"lbl\"\u003eFAQ\u003c\/span\u003e\u003csvg class=\"ico arrow\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-arrow-right\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/nav\u003e\n    \n    \u003cdiv class=\"pp-scorecard\"\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003ePregnancy\u003c\/div\u003e\n\u003cdiv class=\"val warning\"\u003e\n\u003csvg class=\"x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e No\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eFungal Acne\u003c\/div\u003e\n\u003cdiv class=\"val warning\"\u003e\n\u003csvg class=\"x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e No\u003c\/div\u003e\n\u003c\/div\u003e\n      \u003cdiv class=\"item\"\u003e\n\u003cdiv class=\"lbl\"\u003eComedogenic\u003c\/div\u003e\n\u003cdiv class=\"val caution\"\u003e3\/5\u003c\/div\u003e\n\u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"pp-specs\"\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eCategory\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eRx Cream\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eActive\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eIvermectin 1%\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eSize\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003e30g \/ 45g \/ 60g\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eTarget\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eRosacea\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-spec\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eFrequency\u003c\/div\u003e\n\u003cdiv class=\"val\"\u003eOnce Daily\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n    \n    \n    \u003cdiv class=\"pp-highlight\"\u003e\n      \u003cspan class=\"eyebrow\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Why it's different\u003c\/span\u003e\n      \u003ch3\u003eKills Demodex Mites\u003c\/h3\u003e\n      \u003cp\u003eTargets the skin mites linked to inflammation in papulopustular rosacea.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n\n  \u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-sensory\"\u003e\n\u003cspan class=\"eyebrow\"\u003e01\u003c\/span\u003e\u003ch2\u003eTexture \u0026amp; feel\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSENSORY\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-sensory\"\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-droplet\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eConsistency\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eHydrophilic cream\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-wind\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eScent\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eFragrance-free\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eAbsorption\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003e1-2 minutes\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-sensory-item\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-target\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv class=\"label\"\u003eFinish\u003c\/div\u003e\n\u003cdiv class=\"value\"\u003eSoft matte\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-features\"\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eKills Demodex Mites\u003c\/h4\u003e\n\u003cp\u003eTargets the skin mites linked to inflammation in papulopustular rosacea.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eCalms Inflammation\u003c\/h4\u003e\n\u003cp\u003eInhibits lipopolysaccharide-induced cytokine production for anti-inflammatory action.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-trending\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003e83% Lesion Reduction\u003c\/h4\u003e\n\u003cp\u003eIn head-to-head trials against metronidazole over 16 weeks of use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eResults from Week 2\u003c\/h4\u003e\n\u003cp\u003eInitial visible improvement can appear as early as two weeks of daily use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eSingle Daily Dose\u003c\/h4\u003e\n\u003cp\u003eConvenient once-daily application vs. twice-daily for most alternatives.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-feature\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch4\u003eAntibiotic-Free\u003c\/h4\u003e\n\u003cp\u003eNo contribution to antibiotic resistance concerns with long-term topical use.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-safety\"\u003e\n\u003cspan class=\"eyebrow\"\u003e02\u003c\/span\u003e\u003ch2\u003eSafety \u0026amp; compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSAFE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePregnancy \u0026amp; Breastfeeding\u003c\/strong\u003e\n\u003cp\u003eNot recommended. Animal studies showed embryofetal toxicity at high doses; safety in humans not established.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item warning\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eFungal Acne (Malassezia)\u003c\/strong\u003e\n\u003cp\u003eContains oleyl alcohol, isopropyl palmitate, and cetyl\/stearyl alcohols that may feed Malassezia yeast.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-trending\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eInitial Purge Phase\u003c\/strong\u003e\n\u003cp\u003eSkin may worsen in the first 1-2 weeks as Demodex mites die off. This typically resolves within 7 days.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item caution\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eAvoid Eyes \u0026amp; Mucosa\u003c\/strong\u003e\n\u003cp\u003eFor topical skin use only. Do not apply to lips, eyes, mouth, or intravaginal areas.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eNo Systemic Absorption Concerns\u003c\/strong\u003e\n\u003cp\u003ePeak plasma levels are extremely low (~2 ng\/mL) with no expected cardiac or metabolic effects.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item safe\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eLong-Term Use Studied\u003c\/strong\u003e\n\u003cp\u003eSafety demonstrated in 707 patients over 12 months with no serious adverse events reported.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eCYP3A4 Interaction\u003c\/strong\u003e\n\u003cp\u003eUse caution with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) as plasma levels may rise.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eParabens \u0026amp; Propylene Glycol\u003c\/strong\u003e\n\u003cp\u003eContains methyl\/propylparaben and propylene glycol — may cause delayed allergic reaction in sensitive skin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-ingredients\"\u003e\n\u003cspan class=\"eyebrow\"\u003e03\u003c\/span\u003e\u003ch2\u003eIngredient breakdown\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eINGREDIENTS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eIvermectin 1%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eAn antiparasitic agent from the avermectin family of macrocyclic lactones. In topical form, it targets Demodex folliculorum mites while exerting anti-inflammatory effects on the skin.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFDA Approval:\u003c\/strong\u003e Approved December 23, 2014 for inflammatory lesions of rosacea\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical Trial Data:\u003c\/strong\u003e Two Phase 3 studies in 1,371 patients showed superiority over vehicle at 12 weeks\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHead-to-Head:\u003c\/strong\u003e Outperformed metronidazole 0.75% — 83% vs. 73.7% lesion reduction at 16 weeks\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanism:\u003c\/strong\u003e Binds glutamate-gated chloride channels in mites; inhibits inflammatory cytokine production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosing:\u003c\/strong\u003e 10 mg of ivermectin per gram of cream (1% w\/w)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-callout positive\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eUniquely effective for papulopustular rosacea where Demodex density is elevated.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eGlycerin ~3%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA classic humectant that draws moisture into the skin, helping to counter any drying effect from the cream base and supporting barrier recovery.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFunction:\u003c\/strong\u003e Hydration, skin conditioning\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafety:\u003c\/strong\u003e Non-irritating, non-comedogenic, pregnancy-safe in cosmetic use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eDimethicone ~2%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA silicone that forms a light, breathable film to reduce transepidermal water loss and give the cream a silky slip during application.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFunction:\u003c\/strong\u003e Occlusive, smoothing agent\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafety:\u003c\/strong\u003e Considered non-comedogenic and hypoallergenic by most dermatologists\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003eCetyl \u0026amp;amp; Stearyl Alcohol 3.5% + 2.5%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eFatty alcohols that serve as emollients and emulsion stabilizers. They give the cream its rich, hydrating texture — unrelated to drying SD-type alcohols.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFunction:\u003c\/strong\u003e Emulsifier, thickener, skin softener\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNote:\u003c\/strong\u003e May contribute to Malassezia feeding in fungal-acne-prone skin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"pp-warning caution\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\n\u003cdiv\u003eFatty alcohols and isopropyl palmitate make this formula non-fungal-acne-safe.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003ePropylene Glycol ~2%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003eA penetration enhancer and humectant that helps deliver ivermectin into the pilosebaceous unit where Demodex mites reside.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFunction:\u003c\/strong\u003e Solvent, penetration enhancer, humectant\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution:\u003c\/strong\u003e Can cause contact dermatitis in approximately 2-3% of users\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-ingredient\" itemscope itemtype=\"https:\/\/schema.org\/ChemicalSubstance\"\u003e\n\u003cdiv class=\"ing-head\"\u003e\n\u003cdiv class=\"ing-icon\" aria-hidden=\"true\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-flask\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003ch3 itemprop=\"name\"\u003ePhenoxyethanol + Parabens ≤1%\u003cspan class=\"tag proven\"\u003eProven\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003cp class=\"ing-desc\" itemprop=\"description\"\u003ePreservative system combining phenoxyethanol with methylparaben and propylparaben to protect the formula from microbial contamination over a 2-year shelf life.\u003c\/p\u003e\n\u003cul class=\"pp-science\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegulatory Status:\u003c\/strong\u003e All at safe concentrations per FDA \u0026amp; EU Cosmetic Regulation\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNote:\u003c\/strong\u003e Parabens are labeled E218\/E216 and may trigger rare delayed allergic reactions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-accordion\"\u003e\n\u003cinput type=\"checkbox\" id=\"pp-inci\"\u003e\n\u003clabel for=\"pp-inci\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-list\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Full Ingredients (INCI)\u003c\/label\u003e\n\u003cdiv class=\"pp-acc-content\"\u003e\n\u003cp\u003e\u003cstrong\u003e18 ingredients\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIvermectin 1% (Active), Water (Purified), Glycerin, Isopropyl Palmitate, Carbomer Copolymer Type B, Dimethicone, Disodium EDTA (Edetate Disodium), Citric Acid Monohydrate, Cetyl Alcohol, Stearyl Alcohol, PEG-4 Distearyl Ether (Polyoxyl 20 Cetostearyl Ether \/ Ceteareth-20), Sorbitan Stearate (Sorbitan Monostearate), Methylparaben, Propylparaben, Phenoxyethanol, Propylene Glycol, Oleyl Alcohol, Sodium Hydroxide.\u003c\/p\u003e\n\u003cdiv class=\"free-list\"\u003e\n\u003cstrong\u003eFREE FROM:\u003c\/strong\u003e Fragrance, essential oils, dyes, sulfates, silicones (beyond dimethicone), antibiotics, retinoids, benzoyl peroxide, alcohol denat, mineral oil, lanolin.\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-routine\"\u003e\n\u003cspan class=\"eyebrow\"\u003e04\u003c\/span\u003e\u003ch2\u003eWhere it fits in your routine\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eROUTINE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-routine\"\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eGentle Cleanser\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003ePat Dry\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step current\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eSoolantra\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eWait 20 min\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eMoisturizer\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-routine-step\"\u003e\n\u003cdiv class=\"num\"\u003e6\u003c\/div\u003e\n\u003cdiv class=\"name\"\u003eSPF (AM)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cp style=\"text-align:center;color:var(--pp-text-muted);font-size:0.82em;margin-top:12px\"\u003eApply Soolantra as the first leave-on product on clean, fully dry skin. Wait 15-20 minutes before moisturizer to allow the active to reach the follicle.\n\u003c\/p\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-how-to-use\"\u003e\n\u003cspan class=\"eyebrow\"\u003e05\u003c\/span\u003e\u003ch2\u003eHow to use\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eHOW TO USE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-steps\"\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e1\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eCleanse Gently\u003c\/h4\u003e\n\u003cp\u003eWash your face with a mild, non-foaming cleanser. Pat completely dry — applying to damp skin increases irritation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e2\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eTake a Pea-Sized Amount\u003c\/h4\u003e\n\u003cp\u003eDispense a pea-sized amount for each affected area: forehead, chin, nose, and each cheek. Five peas maximum per full-face application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e3\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eApply a Thin Layer\u003c\/h4\u003e\n\u003cp\u003eSpread evenly in a thin layer over the affected zones. Avoid lips, eyes, and inside the nostrils.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e4\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eWash Your Hands\u003c\/h4\u003e\n\u003cp\u003eWash your hands thoroughly after application to avoid transferring the cream to eyes or mucous membranes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e5\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eWait, Then Moisturize\u003c\/h4\u003e\n\u003cp\u003eAllow 15-20 minutes for absorption, then follow with a gentle, barrier-supportive moisturizer.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-step\"\u003e\n\u003cdiv class=\"num\"\u003e6\u003c\/div\u003e\n\u003cdiv\u003e\n\u003ch4\u003eUse Consistently for 12 Weeks\u003c\/h4\u003e\n\u003cp\u003eApply once daily (typically at night). Continue for the full treatment course — courses can be repeated if needed.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-who-is-it-for\"\u003e\n\u003cspan class=\"eyebrow\"\u003e06\u003c\/span\u003e\u003ch2\u003eWho is it for?\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eWHO\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-fit\"\u003e\n\u003cdiv class=\"pp-fit-box yes\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003ePerfect for you if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have papulopustular rosacea (bumps and pustules)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Metronidazole or azelaic acid didn't fully clear your skin\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You want an antibiotic-free long-term option\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You prefer a once-daily routine over twice-daily gels\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You suspect Demodex involvement in your breakouts\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico check\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You need a prescription-strength dermatology treatment\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-fit-box no\"\u003e\n\u003ch4\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003eConsider alternatives if:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are pregnant or breastfeeding\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have erythematotelangiectatic rosacea (redness only, no bumps)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You are prone to fungal acne (Malassezia folliculitis)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You have a known allergy to parabens or propylene glycol\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You need an over-the-counter option\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico x\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e You're looking for a moisturizing skincare product\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-skin-types\"\u003e\n\u003cspan class=\"eyebrow\"\u003e07\u003c\/span\u003e\u003ch2\u003eSkin type compatibility\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSKIN TYPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-skin-grid\"\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eOily Skin\u003c\/div\u003e\n\u003cspan class=\"rate good\"\u003eGood\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eAbsorbs well without heaviness, though isopropyl palmitate may feel slightly occlusive for very oily skin.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eDry Skin\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eCream base with glycerin and fatty alcohols provides comfortable hydration alongside treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eCombination\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eBalanced formula works across different face zones without feeling too heavy or too light.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eSensitive \/ Rosacea\u003c\/div\u003e\n\u003cspan class=\"rate excellent\"\u003eExcellent\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eSpecifically designed for rosacea skin; fragrance-free with anti-inflammatory action. Purge phase expected.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eAcne-Prone\u003c\/div\u003e\n\u003cspan class=\"rate moderate\"\u003eModerate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-good\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eBest for rosacea-type bumps. Contains moderately comedogenic fatty alcohols — not ideal for pure acne sufferers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-skin-card\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"type\"\u003eFungal-Acne-Prone\u003c\/div\u003e\n\u003cspan class=\"rate poor\"\u003ePoor\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"meter tier-moderate\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp class=\"note\"\u003eContains oleyl alcohol, isopropyl palmitate, and fatty alcohols that can feed Malassezia yeast.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-results\"\u003e\n\u003cspan class=\"eyebrow\"\u003e08\u003c\/span\u003e\u003ch2\u003eResults timeline\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eONGOING\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-timeline\"\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeek 1\u003c\/span\u003e\n\u003ch4\u003eInitial Purge \/ Die-Off\u003c\/h4\u003e\n\u003cp\u003eMany users report temporary worsening: new bumps, pustules, and tingling as Demodex mites die and release their bacterial load. Push through — this is expected.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~40% experience purge\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeek 2\u003c\/span\u003e\n\u003ch4\u003eFirst Improvements\u003c\/h4\u003e\n\u003cp\u003eStatistically significant reduction in inflammatory lesions begins. Early responders see calmer skin, fewer new pustules, and reduced burning sensation.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~30% see visible change\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeek 4\u003c\/span\u003e\n\u003ch4\u003eClear Progress\u003c\/h4\u003e\n\u003cp\u003eSignificant lesion count reduction in clinical trials. Redness begins to fade, existing bumps flatten, and skin texture starts to smooth out.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e~60% notice improvement\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeek 12\u003c\/span\u003e\n\u003ch4\u003eFull Clinical Effect\u003c\/h4\u003e\n\u003cp\u003ePrimary endpoint of Phase 3 trials. 38-40% of users rated \"clear\" or \"almost clear\" by investigators. Most users see 70-90% improvement.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e80% show major improvement\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eWeek 16\u003c\/span\u003e\n\u003ch4\u003eBest-in-Class Results\u003c\/h4\u003e\n\u003cp\u003eHead-to-head against metronidazole: 83% mean lesion reduction vs. 73.7%. Many users reach \"clear\" status and begin maintenance regimens.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003e83% lesion reduction\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-tl-item\"\u003e\n\u003cspan class=\"time\"\u003eOngoing\u003c\/span\u003e\n\u003ch4\u003eMaintenance Phase\u003c\/h4\u003e\n\u003cp\u003eTreatment courses can be repeated as needed. Long-term data shows continued safety over 12 months with stable symptom control.\u003c\/p\u003e\n\u003cspan class=\"percent\"\u003eSustained control\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-reviews\"\u003e\n\u003cspan class=\"eyebrow\"\u003e09\u003c\/span\u003e\u003ch2\u003eRatings by platform\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e545+ REVIEWS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-reviews\"\u003e\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eDrugs.com\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 7.7\/10\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e302\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: The initial 1-2 week purge where skin gets visibly worse before it gets better.\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eWebMD\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.0\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e150+\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eReviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Very high cost and inconsistent insurance coverage for the prescription.\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eThe Independent Pharmacy\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.8\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e79%\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003e5-Star Reviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Small 30g tube runs out quickly if applied to larger affected areas.\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eDr Fox Pharmacy\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 4.79\/5\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eRating\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e14\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eVerified Reviews\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Requires patience — noticeable results may take 3-4 weeks of daily use.\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-sparkle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eSermo (Physicians)\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e 5.0\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eSafety\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e4.5\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eEfficacy\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Dermatologists note access and affordability remain barriers for many patients.\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-review-card\"\u003e\n\u003cdiv class=\"platform\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eGalderma \/ Brand Website\u003c\/div\u003e\n\u003cdiv class=\"stats\"\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e\n\u003cdiv class=\"meter\"\u003e\n\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\u003cspan class=\"on\"\u003e\u003c\/span\u003e\n\u003c\/div\u003e FDA\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eApproved\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"stat\"\u003e\n\u003cdiv class=\"num\"\u003e1,371\u003c\/div\u003e\n\u003cdiv class=\"lbl\"\u003eTrial Patients\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"complaint\"\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"display:inline-block;width:14px;height:14px;vertical-align:middle\"\u003e\u003cuse href=\"#i-info\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Main complaint: Brand-name pricing significantly higher than metronidazole generics on the market.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"0\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-pros-cons\"\u003e\n\u003cspan class=\"eyebrow\"\u003e10\u003c\/span\u003e\u003ch2\u003ePros \u0026amp; cons\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eBALANCED\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-proscons\"\u003e\n\u003cdiv class=\"pp-pc pros\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003ePraised\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Clinically superior to metronidazole for papulopustular rosacea\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Fragrance-free, once-daily convenience\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Dual action: anti-parasitic + anti-inflammatory\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Results visible as early as week 2\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e No antibiotic resistance concerns\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Excellent long-term safety profile (12+ months studied)\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Suitable for most skin types including sensitive\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-pc cons\"\u003e\n\u003ch4\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003eCriticized\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Expensive — brand can exceed $500 per tube in the US\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Prescription-only; requires dermatologist visit\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Initial purge phase can be discouraging\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Not safe during pregnancy or breastfeeding\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Not suitable for fungal acne-prone skin\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Mainly targets bumps — less effective for pure redness\u003c\/li\u003e\n\u003cli\u003e\n\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-x\"\u003e\u003c\/use\u003e\u003c\/svg\u003e Contains parabens and propylene glycol\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"50\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-dupes\"\u003e\n\u003cspan class=\"eyebrow\"\u003e11\u003c\/span\u003e\u003ch2\u003eBudget-friendly alternatives (dupes)\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eDUPES\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-dupes\"\u003e\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match high\"\u003e95% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"photo-fallback\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003eGeneric Ivermectin 1% Cream\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e$40-175\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eBest Value\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eChemically identical active and nearly identical inactive ingredients. The most effective dupe by far, especially via Canadian or international pharmacies.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e70% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"photo-fallback\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003eMetronidazole 0.75% Cream (MetroCream \/ Rozex)\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e$30-50\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eBudget Pick\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eDifferent mechanism (antibiotic) but addresses the same condition. Clinically less effective by ~10% in head-to-head trials but a fraction of the cost.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match medium\"\u003e65% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/azelaic-acid-suspension-10\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/e6nowd9fynzq521vdeidzhcm5dms.jpg?v=1766239026\" alt=\"Azelaic Acid Suspension 10%\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/azelaic-acid-suspension-10\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003eAzelaic Acid 15-20% (Finacea \/ The Ordinary)\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e$8-45\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eBudget Pick\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eThe Ordinary Azelaic Acid 10% is an OTC alternative at ~$8. Works on both redness and bumps with anti-inflammatory and keratinocyte-normalizing action.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-dupe-card\"\u003e\n\u003cspan class=\"match low\"\u003e50% Match\u003c\/span\u003e\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"photo-fallback\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"name\"\u003eSulfur 5% Face Cream (De La Cruz)\u003c\/div\u003e\n\u003cdiv class=\"price-row\"\u003e\n\u003cdiv class=\"amount\"\u003e$8\u003c\/div\u003e\n\u003cdiv class=\"tag budget\"\u003eBudget Pick\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"diff\"\u003eOTC sulfur has mild anti-Demodex activity and is used off-label for rosacea. Less effective than ivermectin but cheap and widely available.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"100\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-compare\"\u003e\n\u003cspan class=\"eyebrow\"\u003e12\u003c\/span\u003e\u003ch2\u003eComparison with competitors\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eSIDE-BY-SIDE\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-compare\"\u003e\n\u003cdiv class=\"pp-compare-card featured\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/soolantra\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/mr9i3zf0e8r3qrm556ojijhofct8_square_be5b81bc-1578-4ab5-94e2-9bc287176742.png?v=1774477757\" alt=\"Soolantra\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/soolantra\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003eSoolantra (Galderma) — Featured\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eIvermectin 1%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eMechanism\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eAnti-parasitic + Anti-inflammatory\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFrequency\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eOnce daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eLesion Reduction (16 wk)\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003e83.0%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eOnset\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eWeek 2-4\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eSize\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e30g \/ 45g \/ 60g\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003eMetroGel 1% (Galderma)\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eMetronidazole 1%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eMechanism\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eAntibiotic\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFrequency\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eOnce daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eLesion Reduction (16 wk)\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003e73.7%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eOnset\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eWeek 2-4\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eSize\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e45g\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003ca href=\"https:\/\/www.skincarisma.com\/products\/finacea-15-gel-azelaic-acid\" target=\"_blank\" rel=\"noopener\" style=\"display:block;width:100%;height:100%\"\u003e\u003cimg class=\"pp-product-photo\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/1wipa0gmsmp36mz204zb5jcch4ac_square_ffa4bfef-7299-459f-92a3-fbd6fd562f75.png?v=1773788390\" alt=\"Finacea 15% Gel Azelaic Acid\" loading=\"lazy\" width=\"200\" height=\"200\" style=\"display:block;width:100%;height:100%;object-fit:cover\"\u003e\u003c\/a\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ca href=\"https:\/\/www.skincarisma.com\/products\/finacea-15-gel-azelaic-acid\" target=\"_blank\" rel=\"noopener\" style=\"color:inherit;text-decoration:none\"\u003e\u003ch4\u003eFinacea 15% Gel (LEO Pharma)\u003c\/h4\u003e\u003c\/a\u003e\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eAzelaic Acid 15%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eMechanism\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eAnti-inflammatory + Keratinocyte\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFrequency\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eTwice daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eLesion Reduction (16 wk)\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003e~65-70%\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eOnset\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eWeek 4-8\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eSize\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e30g \/ 50g\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-card\"\u003e\n\u003cdiv class=\"photo\"\u003e\u003cdiv class=\"placeholder\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\" style=\"width:36px;height:36px;color:var(--pp-ink-3)\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"head\"\u003e\n\u003ch4\u003eMirvaso 0.33% Gel (Galderma)\u003c\/h4\u003e\n\u003cdiv class=\"price\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"body\"\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eActive Ingredient\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eBrimonidine Tartrate\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eMechanism\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eVasoconstrictor (redness only)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eFrequency\u003c\/span\u003e\n\u003cspan class=\"value neutral\"\u003eOnce daily\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eTargets Bumps\u003c\/span\u003e\n\u003cspan class=\"value bad\"\u003eNo — redness only\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eOnset\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003e30 minutes (temporary)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eAntibiotic-Free\u003c\/span\u003e\n\u003cspan class=\"value good\"\u003eYes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-compare-row\"\u003e\n\u003cspan class=\"label\"\u003eSize\u003c\/span\u003e\n\u003cspan class=\"value\"\u003e30g\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"150\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-storage\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eStorage \u0026amp; shelf life\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003e24 MONTHS\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-safety\"\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-clock\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePeriod After Opening (PAO)\u003c\/strong\u003e\n\u003cp\u003e24 months (unopened). Typically 6-12 months after opening for topical prescription creams.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-shield-check\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eStorage\u003c\/strong\u003e\n\u003cp\u003eStore at 20°C to 25°C (68°F to 77°F). Excursions permitted between 15°C and 30°C. Do not freeze.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-bottle\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePackaging\u003c\/strong\u003e\n\u003cp\u003eLaminated aluminum tube with child-resistant cap. Available in 30g, 45g, and 60g sizes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-safety-item info\"\u003e\n\u003cdiv class=\"ico-wrap\"\u003e\u003csvg class=\"ico\" viewbox=\"0 0 24 24\"\u003e\u003cuse href=\"#i-package\"\u003e\u003c\/use\u003e\u003c\/svg\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTravel Friendly\u003c\/strong\u003e\n\u003cp\u003eYes — all tube sizes are well under 100ml and TSA carry-on compliant. Keep in original packaging.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cmotion-element data-motion=\"fade-up\" data-motion-delay=\"200\"\u003e\u003cdiv class=\"pp-title\" id=\"pp-faq\"\u003e\n\u003cspan class=\"eyebrow\"\u003e13\u003c\/span\u003e\u003ch2\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cspan class=\"num\"\u003eFAQ\u003c\/span\u003e\n\u003c\/div\u003e\u003c\/motion-element\u003e\n \n\u003cdiv class=\"pp-faq\"\u003e\n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq1\"\u003e\n\u003clabel for=\"faq1\"\u003eIs Soolantra pregnancy and breastfeeding safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eNo. Soolantra is not recommended during pregnancy or breastfeeding. Although topical absorption is low, animal studies at high oral doses have shown embryofetal toxicity, and it is not known whether ivermectin passes into breast milk. It was previously classified as FDA pregnancy category C. If you are pregnant, planning pregnancy, or nursing, speak with your dermatologist about alternatives such as azelaic acid, which has a more favorable pregnancy profile.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq2\"\u003e\n\u003clabel for=\"faq2\"\u003eIs Soolantra fungal acne (malassezia) safe?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eNo. Soolantra contains several ingredients that can feed Malassezia yeast, including oleyl alcohol, isopropyl palmitate, cetyl alcohol, and stearyl alcohol. If you have fungal acne (pityrosporum folliculitis), these ingredients may worsen your condition. However, if your breakouts are truly papulopustular rosacea (Demodex-driven), the antiparasitic action of ivermectin typically outweighs the fungal-acne concern. A dermatologist can help distinguish the two.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq3\"\u003e\n\u003clabel for=\"faq3\"\u003eCan I use Soolantra with retinol, vitamin C, AHA, or BHA?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eWith caution. Combining Soolantra with strong actives can significantly increase irritation, especially during the first few weeks. A common approach is to use Soolantra at night and a gentle vitamin C in the morning, or to alternate nights with retinol once your skin has adjusted (typically after week 4-6). Avoid AHA\/BHA exfoliants during the purge phase. Always wait at least 20-30 minutes between products and prioritize barrier-supportive moisturizers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq4\"\u003e\n\u003clabel for=\"faq4\"\u003eWhat skin type is Soolantra best for?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eSoolantra is best for adults with papulopustular rosacea — characterized by persistent redness combined with acne-like bumps and pustules on the central face. It is excellent for sensitive, dry, and combination skin types with rosacea. It is less ideal for fungal-acne-prone skin or for people whose primary concern is diffuse flushing or visible blood vessels (erythematotelangiectatic rosacea), for which Mirvaso, Rhofade, or laser therapy may be more appropriate.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq5\"\u003e\n\u003clabel for=\"faq5\"\u003eHow long until I see results from Soolantra?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eIn Phase 3 clinical trials, statistically significant improvement was observed as early as week 2. Most users see clear progress by weeks 4-6, with full results at 12-16 weeks of daily use. Be prepared for an initial purge (worsening) in the first 1-2 weeks as Demodex mites die off and release bacterial content — this is normal and expected. Push through: the majority of users who persist achieve 70-90% lesion clearance by week 12.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq6\"\u003e\n\u003clabel for=\"faq6\"\u003eWhere does Soolantra go in my skincare routine?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eApply Soolantra to completely clean, dry skin as the first leave-on product — after cleansing, before moisturizer. Use a pea-sized amount per affected zone (forehead, chin, nose, each cheek) and spread in a thin layer. Wait 15-20 minutes for the cream to absorb and reach the follicle, then apply your moisturizer. In the morning, always finish with a mineral-based SPF, as rosacea skin is highly sun-sensitive.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq7\"\u003e\n\u003clabel for=\"faq7\"\u003eIs Soolantra comedogenic \/ will it clog pores?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eMildly comedogenic — rated approximately 3\/5. The formula contains isopropyl palmitate (4\/5) and fatty alcohols (2\/5) that can contribute to pore-clogging in very acne-prone skin. However, for its target audience (rosacea sufferers), the anti-inflammatory and antiparasitic benefits far outweigh the comedogenic concern. If you have combination acne-rosacea, monitor for comedonal breakouts and consider pairing with a non-comedogenic moisturizer.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n \n\u003cdiv class=\"pp-faq-item\"\u003e\n\u003cinput type=\"checkbox\" id=\"faq8\"\u003e\n\u003clabel for=\"faq8\"\u003eHow long does Soolantra last after opening?\u003c\/label\u003e\n\u003cdiv class=\"pp-faq-answer\"\u003e\n\u003cp\u003eSoolantra has an unopened shelf life of 24 months when stored between 20-25°C (68-77°F). Once opened, it should generally be used within 6-12 months, though the FDA-approved prescribing information does not specify a separate post-opening expiry. Always check the printed expiration date on the tube, avoid extreme heat, do not freeze, and discard if the cream changes color, texture, or odor.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"pp-verdict\"\u003e\n    \u003cdiv class=\"eyebrow\"\u003e— Skincarisma verdict\u003c\/div\u003e\n    \u003cdiv class=\"score-row\"\u003e\n      \u003cspan class=\"score\"\u003e4.5\u003c\/span\u003e\n      \u003cspan class=\"max\"\u003e\/ 5\u003c\/span\u003e\n      \u003cspan class=\"stars\"\u003e★★★★★\u003c\/span\u003e\n    \u003c\/div\u003e\n    \u003cp class=\"text\"\u003e\n\u003cstrong\u003eVerdict:\u003c\/strong\u003e Soolantra is the gold-standard topical prescription for papulopustular rosacea, and for good reason. Its unique dual action — killing Demodex mites while calming inflammation — delivers clinically superior results to metronidazole and azelaic acid in head-to-head trials. The once-daily, antibiotic-free, fragrance-free formula is gentle enough for long-term use and has a strong safety record over 12+ months. The initial purge phase and high brand-name cost are real drawbacks, and it is not suitable for pregnancy, breastfeeding, or fungal-acne-prone skin. But for the right patient, few rosacea treatments are as life-changing. Worth every penny if your dermatologist confirms Demodex-driven rosacea.\n\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003cbutton class=\"pp-back-to-top\" aria-label=\"Back to top\" type=\"button\" style=\"position:fixed;bottom:24px;right:24px;width:44px;height:44px;border-radius:50%;background:var(--pp-accent);color:#fff;border:none;display:none;cursor:pointer;z-index:50;box-shadow:0 4px 16px rgba(13,31,45,0.2)\"\u003e↑\u003c\/button\u003e\n  \u003cscript\u003e\n  (function () {\n    var btt = document.querySelector('.pp-back-to-top');\n    if (!btt) return;\n    var ticking = false;\n    function onScroll () {\n      if (!ticking) {\n        requestAnimationFrame(function () {\n          btt.style.display = window.scrollY \u003e 600 ? 'block' : 'none';\n          ticking = false;\n        });\n        ticking = true;\n      }\n    }\n    window.addEventListener('scroll', onScroll, { passive: true });\n    btt.addEventListener('click', function () { window.scrollTo({ top: 0, behavior: 'smooth' }); });\n  })();\n  \u003c\/script\u003e\n\u003c\/div\u003e\n","brand":"Galderma","offers":[{"title":"Default Title","offer_id":52164220584279,"sku":null,"price":101.23,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/5028\/8215\/files\/mr9i3zf0e8r3qrm556ojijhofct8_square_be5b81bc-1578-4ab5-94e2-9bc287176742.png?v=1774477757","url":"https:\/\/www.skincarisma.com\/products\/soolantra","provider":"Skincarisma","version":"1.0","type":"link"}