Panthenol — Skincare Ingredient
Panthenol
Reduces transepidermal water loss (TEWL) — locks in moisture
Also known as: Pro-Vitamin B5 · D-Panthenol
What is Panthenol?
Pro-vitamin B5 — converts to pantothenic acid in skin. Humectant + anti-inflammatory + barrier support all in one.
What Panthenol Does
- Reduces transepidermal water loss (TEWL) — locks in moisture
- Soothes irritation and redness
- Supports barrier repair after sun, retinol, or AHA irritation
Skin Type Compatibility
How well Panthenol works for each skin type:
How to Use Panthenol
Layering Panthenol
How Panthenol combines with other actives in your routine:
Panthenol in Our Catalog
- COSRX48
- Round Lab33
- Cetaphil29
- Isntree28
- Anua26
Browse Products with Panthenol












Frequently Asked Questions
What is Panthenol?
Pro-vitamin B5 — converts to pantothenic acid in skin. Humectant + anti-inflammatory + barrier support all in one.
What does Panthenol do for skin?
Reduces transepidermal water loss (TEWL) — locks in moisture Soothes irritation and redness Supports barrier repair after sun, retinol, or AHA irritation
Is Panthenol safe during pregnancy?
Yes — Panthenol is generally considered safe to use during pregnancy and breastfeeding.
What skin types is Panthenol good for?
Panthenol works well for All skin types, Dry skin, Sensitive skin, Post-procedure.
How do I use Panthenol?
Effective at 1-5%. Pregnancy-safe. Pairs well with almost everything.
What is the comedogenic rating of Panthenol?
Panthenol has a comedogenic rating of 0/5 — non-comedogenic, safe for acne-prone skin.
What is the irritation potential of Panthenol?
Panthenol has an irritation risk score of 0/5 — very low, safe for sensitive skin.
What ingredients pair well with Panthenol?
Panthenol layers beautifully with: Niacinamide, Hyaluronic Acid, Ceramide Np.
Related Ingredients
Often used together with or similar to Panthenol:

