10% Niacinamide Serum For Acne Marks
10% Niacinamide Serum For Acne Marks
Product Description
Product overview
The Derma Co 10% Niacinamide Serum is a high-potency, dermatologist-formulated serum powered by 10% Niacinamide and 2% Zinc PCA — a clinically proven duo that visibly fades acne marks, controls excess sebum, minimizes enlarged pores, and evens out skin tone. Lightweight, fast-absorbing, and suitable for all skin types, it's one of India's most-reviewed niacinamide serums with over 50,000 user ratings across platforms.
Fades Acne Marks & Dark Spots
10% Niacinamide inhibits melanin transfer to skin cells, visibly reducing post-acne hyperpigmentation, PIH (post-inflammatory hyperpigmentation), and dark spots with consistent use.
Texture & feel
SENSORYFades Acne Marks & Dark Spots
10% Niacinamide inhibits melanin transfer to skin cells, visibly reducing post-acne hyperpigmentation, PIH (post-inflammatory hyperpigmentation), and dark spots with consistent use.
Controls Oil & Sebum Production
The synergistic combination of Niacinamide and 2% Zinc PCA regulates excess sebum, reducing shine and keeping skin balanced without drying it out.
Minimizes Enlarged Pores
By normalizing sebum and improving skin texture, regular use helps tighten and refine the appearance of enlarged pores for a smoother complexion.
Strengthens Skin Barrier
Niacinamide boosts ceramide production, reinforcing the skin's natural protective barrier to retain moisture, defend against environmental stressors, and reduce sensitivity.
Brightens & Evens Skin Tone
By inhibiting excess melanin production and supporting cell renewal, this serum works to create a more uniform, radiant complexion over time.
Hydrates Without Heaviness
Glycerin and Sodium Gluconate deliver lightweight hydration that plumps skin without clogging pores, making it ideal for oily, combination, and acne-prone skin types.
Safety & compatibility
SAFEContains no retinoids, salicylic acid, hydroquinone, or unsafe chemical actives. Niacinamide is considered safe during pregnancy and breastfeeding. Consult your dermatologist for personalized advice.
The formula contains no fermented ingredients, fatty acid esters, or polysorbates that feed Malassezia yeast. Confirmed fungal acne safe by ingredient analysis.
No pore-clogging oils, silicones, or heavy emollients in the formula. Glycerin and Propylene Glycol are rated 0 on the comedogenic scale. Safe for acne-prone skin.
Preservative system uses Phenoxyethanol, Diazolidinyl Urea, Ethylhexylglycerin, and Iodopropynyl Butylcarbamate — no parabens or sulfates in the formula.
The formula includes Parfum (fragrance), which may cause irritation for individuals with highly sensitive skin or known fragrance allergies. Perform a patch test before first use.
10% is on the higher end for niacinamide serums. First-time users with sensitive skin may experience mild redness or tingling during the initial 1–2 weeks of use. Start with once-daily application to build tolerance.
Safe to use alongside Vitamin C serums, but recommended to apply Vitamin C in the morning and this Niacinamide serum in the evening to maximize benefits and avoid any potential interaction.
Niacinamide pairs well with chemical exfoliants to enhance post-exfoliation barrier recovery. Use the exfoliant first, allow skin to fully dry, then apply this serum for best results.
Ingredient breakdown
INGREDIENTSNiacinamide 10%Proven
The hero active in this serum. Niacinamide (Vitamin B3) is second on the ingredient list, confirming a genuine high-concentration formula. It converts to NAD (nicotinamide adenine dinucleotide) in skin cells — a coenzyme that powers barrier repair, melanin regulation, sebum control, and collagen support.
- Fades Pigmentation: Inhibits melanosome transfer from melanocytes to keratinocytes, reducing post-acne marks and dark spots.
- Pore Refinement: Normalizes follicular keratinization, helping reduce visible pore size with regular use.
- Sebum Regulation: Clinically reduces sebum excretion rate; studies demonstrate measurable improvement at 2–5% concentrations, with compounding effects at 10%.
- Barrier Strengthening: Boosts ceramide and free fatty acid synthesis in the stratum corneum, improving TEWL (transepidermal water loss).
- Anti-Inflammatory: Suppresses pro-inflammatory cytokines, soothing acne-related redness and irritation.
Zinc PCA ~2%Proven
A synergistic combination of Zinc (antimicrobial) and L-PCA (a natural moisturizing factor). Zinc PCA is especially valued in acne-prone and oily skin formulations for its dual action: it reduces sebum production while simultaneously hydrating the skin through the NMF (natural moisturizing factor) component.
- Antimicrobial: In-vitro studies show Zinc PCA has strong anti-microbial activity against P. acnes bacteria at concentrations of 0.1–0.25%.
- Sebum Control: In-vivo testing by ingredient manufacturers shows statistically significant reduction in sebum production after 28 days at 1% concentration.
- Skin Hydration: The PCA (pyrrolidone carboxylic acid) component is an NMF that supports skin hydration and energy processes.
- Enhanced Bioavailability: PCA increases the efficacy and skin absorption of Zinc, making this combination more effective than zinc alone.
Glycerin ~3–5%Proven
A skin-identical humectant that draws moisture from the environment into the skin. Glycerin supports the skin's natural lipid structure between cells, aids barrier repair, and protects against irritation. A 2016 study found glycerin to be more effective as a humectant than AHAs and hyaluronic acid in certain conditions.
- Comedogenicity: Rated 0/5 — does not clog pores.
- Effective Concentration: Benefits skin from as low as 3%, with more significant dry skin benefits at 20–40%.
- Barrier Support: Keeps skin lipids in a healthy liquid crystal state for optimal barrier function.
Propylene Glycol ~2–4%Proven
A multifunctional ingredient acting as a humectant, penetration enhancer, and antimicrobial. It helps active ingredients like Niacinamide absorb more efficiently into the skin while also extending product shelf life. Despite controversy in natural beauty circles, it is widely regarded as safe and effective by cosmetic scientists and toxicology experts.
- Penetration Enhancement: Increases the skin absorption rate of active ingredients, improving overall efficacy.
- Stabilizer: Prevents the product from freezing or melting in extreme temperatures.
Ethoxydiglycol ~1–2%Promising
A synthetic solvent and superior penetration enhancer used to boost the delivery of active ingredients such as Niacinamide into deeper skin layers. Also used as a co-solvent to maintain formula stability and even distribution of ingredients throughout the product.
- Efficacy Booster: Recognized by manufacturers as a superior solubilizer for key skincare actives.
- Uniform Distribution: Helps ensure even delivery of actives across the skin surface.
Phenoxyethanol ≤1%Proven
The primary preservative in this formula. Phenoxyethanol is a well-established, globally approved preservative with germicidal and antimicrobial properties. It's considered a safe, gentler alternative to parabens, approved for use up to 1% worldwide. Introduced around 1950, it's also naturally found in green tea.
- Broad Spectrum: Prevents microbial contamination across a wide range of organisms.
- Safety Profile: Extensively studied and approved by regulatory authorities globally at ≤1% concentrations.
15 ingredients
Water, Niacinamide, Propylene Glycol, Glycerin, Zinc PCA, Ethoxydiglycol, Phenoxyethanol, Hydroxyethylcellulose, Xanthan Gum, Citric Acid, Parfum, Diazolidinyl Urea, Ethylhexylglycerin, Sodium Gluconate, Iodopropynyl Butylcarbamate
Where it fits in your routine
ROUTINEApply after toner on clean, dry skin. Always follow with moisturizer. Use SPF in the morning — niacinamide does not increase sun sensitivity, but daily sun protection is key to preventing new marks.
How to use
HOW TO USECleanse & Prep
Wash your face with a gentle cleanser and pat skin dry. If using a toner, apply it first and allow it to absorb before applying the serum.
Dispense 2–3 Drops
Shake lightly if needed, then dispense 2–3 drops of serum onto your fingertips or directly onto your face and neck.
Apply & Massage Gently
Using gentle upward strokes, apply the serum across your entire face and neck. Avoid the immediate eye area. Pat — don't rub — to maximize absorption.
Follow with Moisturizer
Once the serum has absorbed (usually under 30 seconds), apply your regular moisturizer to seal in the actives and maintain hydration levels.
Apply SPF in the Morning
Always apply a broad-spectrum sunscreen (SPF 30 or higher) as the final step of your morning routine. Sun protection is essential to prevent new acne marks from forming.
Frequency: Twice Daily
Use morning and evening for best results. If you have sensitive skin, start with once daily (evening) for the first 1–2 weeks before increasing frequency.
Who is it for?
WHOPerfect for you if:
- You have oily, acne-prone, or combination skin
- You want to fade post-acne marks, PIH, or dark spots
- You're dealing with enlarged pores and excess shine
- You're building your first serious skincare routine
- You want a high-concentration niacinamide at an affordable price
- You're pregnant or breastfeeding and need safe actives
- You have fungal acne and need a safe serum option
Consider alternatives if:
- You have extreme fragrance sensitivity (contains Parfum)
- You have very dry skin needing richer, occlusive actives
- You're looking for anti-aging as the primary concern (consider adding peptides)
- You've previously reacted to Propylene Glycol or Diazolidinyl Urea
- You need a completely fragrance-free clinical formula
Skin type compatibility
SKIN TYPESIdeal choice. Niacinamide + Zinc PCA directly target excess sebum, shine, and enlarged pores. Absorbs instantly without adding greasiness.
Tackles acne at multiple angles: reduces P. acnes activity, regulates sebum, calms inflammation, and fades post-acne marks. Non-comedogenic and fungal acne safe.
Balances the T-zone without over-drying cheeks. Lightweight texture performs well across different facial zones simultaneously.
Niacinamide is generally well-tolerated, but the 10% concentration and presence of Parfum warrant a patch test first. Start with once-daily use and build up.
Glycerin and Sodium Gluconate provide lightweight hydration. However, dry skin types may need a richer moisturizer on top to prevent any tightness, especially in winter.
Works beautifully as a preventative and maintenance serum for normal skin. Supports barrier function, evens tone, and helps keep pores clear.
Results timeline
WEEK 8–12+Oil Control & Texture Improvement
Most users notice a reduction in midday shine and excess oiliness within the first two weeks. Skin texture begins to feel smoother and less congested as sebum production starts to normalize.
78% noticedPore Refinement & Reduced Breakouts
Pores begin to appear smaller and less visible as follicular keratinization improves. Many users report fewer active breakouts and a reduction in new blemishes forming due to antimicrobial action of Zinc PCA.
65% noticedAcne Mark Fading & Brighter Skin Tone
Post-acne marks (PIH), red spots, and uneven skin tone begin to visibly fade as niacinamide inhibits melanin transfer. Skin appears noticeably more radiant, even, and luminous at this stage.
70% noticedSignificant Tone Correction & Barrier Strengthening
Long-term use delivers compounding benefits including substantial reduction in hyperpigmentation, improved skin elasticity from increased ceramide production, and a noticeably stronger, more resilient skin barrier.
85% noticedRatings by platform
54K+ REVIEWSPros & cons
BALANCEDPraised
- Genuinely high 10% niacinamide concentration confirmed by ingredient listing position
- Affordable price point — excellent value for money
- Fast-absorbing, non-greasy, lightweight texture
- Noticeably reduces shine and controls sebum
- Dermatologist tested and formulated
- Pregnancy safe, fungal acne safe, non-comedogenic
- Visible acne mark fading in 4–8 weeks
- Suitable for all skin types including sensitive
- Over 50,000 verified reviews across major platforms
Criticized
- Contains Parfum — not fully fragrance-free
- 10% concentration may cause mild initial tingling for sensitive users
- Small 30ml bottle size — goes quickly with twice-daily use
- Some users experience initial skin dryness in week 1–2
- Budget packaging (glass dropper or simple bottle) — not premium feel
- Contains Diazolidinyl Urea preservative, a formaldehyde-releasing agent at very low concentrations
Budget-friendly alternatives (dupes)
DUPESNearly identical active concept — 10% niacinamide with zinc PCA — at a similar price. The Ordinary's formula is fragrance-free (no Parfum) and has a slightly more minimal ingredient list. Texture is very similar gel serum. Main difference: lower zinc concentration (1% vs 2%) and no glycerin or sodium gluconate for extra hydration. Best fragrance-free alternative.
Another Indian brand offering 10% niacinamide with added zinc and hyaluronic acid for extra hydration. Formula is more hydrating than The Derma Co version, making it better for dry or dehydrated skin. Fragrance-free. Slightly richer texture. A good dupe if you want more moisture in the same step.
A K-beauty option at 15% niacinamide — higher concentration with added peptides and ceramides for anti-aging synergy. More premium formula in a larger bottle. Better suited for mature or barrier-compromised skin. Not a direct budget dupe, but worth considering if you want a more comprehensive niacinamide serum with anti-aging support.
Comparison with competitors
SIDE-BY-SIDEStorage & shelf life
12 MONTHS12 months after opening. Discard if you notice changes in color, smell, or texture before that time.
Store in a cool, dry place away from direct sunlight and heat. Avoid bathroom storage if humidity is high. Room temperature (below 25°C / 77°F) is ideal.
Compact glass dropper or pump bottle (30ml). Dropper design minimizes product contamination and allows precise dosing. Packaging is practical though not premium in appearance.
Yes — 30ml bottle is within the 100ml TSA/airline liquid limit for carry-on luggage. Compact size is ideal for travel routines.
Frequently asked questions
FAQYes, The Derma Co 10% Niacinamide Serum is considered safe for use during pregnancy and breastfeeding. The formula contains no retinoids, salicylic acid, hydroquinone, or chemical sunscreens that are commonly contraindicated during pregnancy. Niacinamide (Vitamin B3) is a water-soluble vitamin that is generally regarded as safe. However, as with all skincare products during pregnancy, it is always best practice to consult your obstetrician or dermatologist before starting or continuing any new skincare active. The mild fragrance (Parfum) is present at low levels, but if you prefer to completely minimize fragrance exposure during pregnancy, consider The Ordinary Niacinamide 10% + Zinc 1% as a fragrance-free alternative.
Yes, The Derma Co 10% Niacinamide Serum is fungal acne (Malassezia folliculitis) safe. The formula does not contain fermented ingredients, fatty acid esters, polysorbates, or problematic oils that feed Malassezia yeast — the organism responsible for fungal acne. All 15 ingredients have been verified against the standard fungal acne safe checklist. Niacinamide is actually beneficial for fungal acne-prone skin due to its anti-inflammatory and sebum-regulating properties, which help reduce the oily environment in which Malassezia thrives.
Yes, niacinamide is compatible with all of these actives, but timing matters. With Vitamin C: Use Vitamin C in the morning and this Niacinamide serum in the evening to maximize each active's benefits — at high concentrations, niacinamide and pure L-ascorbic acid Vitamin C can potentially interact. With Retinol: Niacinamide pairs well with retinol and can actually help buffer retinol-related irritation. Apply the niacinamide serum before or after retinol. With AHA/BHA: Niacinamide is excellent for supporting skin barrier recovery post-exfoliation. Apply the exfoliant first, allow skin to dry, then apply this serum. Daily niacinamide use alongside 2–3x weekly chemical exfoliation is a very effective combination for acne marks.
This serum is most effective for oily, acne-prone, and combination skin types, where its sebum-regulating and anti-blemish properties deliver the most noticeable results. It is also suitable for normal skin as a preventative and maintenance serum. Dry skin types can use it, but will need a richer moisturizer applied immediately after to counterbalance the potentially matte finish. Sensitive skin types should perform a patch test first and start with once-daily use due to the high 10% niacinamide concentration and presence of Parfum. All skin types dealing with post-acne marks or uneven tone will benefit from the pigmentation-fading properties.
Results appear in stages with consistent twice-daily use. Most users notice oil control and texture improvements within the first 1–2 weeks. Visible pore refinement and fewer breakouts typically emerge by weeks 3–4. Acne mark fading and a more even skin tone become noticeable between weeks 4–8. The most significant long-term benefits — including substantial tone correction and a stronger skin barrier — develop after 8–12 weeks of regular use. For best and fastest results, pair this serum with a broad-spectrum SPF 30+ sunscreen every morning, as UV exposure is the primary factor that darkens and prolongs post-acne marks.
This serum belongs in the serum step of your routine, applied after cleansing and toning but before moisturizer. The recommended order is: (1) Cleanser → (2) Toner → (3) This Niacinamide Serum → (4) Eye Cream (if used) → (5) Moisturizer → (6) Sunscreen (morning only). As a water-based serum, it should be applied before any oils, cream serums, or heavy moisturizers. If layering multiple serums, apply this one first as it is the most lightweight. Allow it to absorb for 20–30 seconds before the next step. Use both morning and evening for optimal results.
No, this serum is non-comedogenic with a comedogenic rating of 1/5. The formula contains no pore-clogging oils, silicones, or heavy emollients. The two primary moisturizing ingredients — Glycerin and Propylene Glycol — are both rated 0 on the comedogenic scale, meaning they are extremely unlikely to block pores. In fact, the combination of Niacinamide and Zinc PCA in this serum actively works to reduce pore visibility by normalizing sebum production and improving follicular keratinization. It is specifically formulated for acne-prone and oily skin types, making pore-clogging an extremely unlikely concern.
The serum has a Period After Opening (PAO) of 12 months. With twice-daily use of 2–3 drops per application, the 30ml bottle typically lasts approximately 2–3 months. To maximize shelf life, store the product in a cool, dry place away from direct sunlight and avoid contaminating the dropper tip by touching it to the skin. If you notice any changes in color, consistency, or scent before the 12-month mark, discontinue use. The 30ml size makes it travel-friendly and within airline carry-on liquid limits (under 100ml).
Verdict: The Derma Co 10% Niacinamide Serum is one of the most compelling value propositions in the niacinamide serum category. It delivers a genuinely high-concentration, dermatologist-developed formula with 10% Niacinamide and 2% Zinc PCA — two clinically supported actives for oily, acne-prone skin — at a price that remains accessible. With over 50,000 user reviews confirming real-world results for acne mark fading, sebum control, and pore refinement, this serum has earned its reputation as a go-to in both beginner and experienced Indian skincare routines. The only notable caveats are the presence of Parfum (not fully fragrance-free) and a packaging style that doesn't match its clinical efficacy. For oily, combination, or acne-prone skin seeking visible pigmentation improvement and oil control without breaking the bank, this is an excellent choice and a strong competitor to international brands at a fraction of the price.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 3 |
Propylene Glycol
Solvent, Skin Conditioning, Fragrance, Humectant, Viscosity Controlling, Viscosity Decreasing Agent, Skin-Conditioningagent - Miscellaneous
|
Hydrating
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 0 |
Zinc PCA
|
Promotes Wound Healing
Redness
|
|
| 1 |
Ethoxydiglycol
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent
|
|
|
| 4 |
Phenoxyethanol
Fragrance, Preservative
|
|





