Skip to content

100% Squalane Oil

100% Squalane Oil

Product Description

Product overview

Made in Various INTERNATIONAL

A weightless, multitasking pure squalane oil derived from sustainable sugarcane that rapidly hydrates from head to toe. Bioidentical to your skin's natural moisture, this single-ingredient powerhouse locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

Vegan Cruelty-Free EWG Verified Non-Comedogenic Fragrance-Free Dermatologist Tested Hypoallergenic Saves 2M Sharks/Year
Pregnancy
Yes
Fungal Acne
Yes
Comedogenic
0/5
Size
100ml / 3.3oz
Form
Pure Oil
Source
Sugarcane
pH Level
N/A (Oil)
Target
Face/Body/Hair
Real reviews · YouTube Shorts
Why it's different

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

01

Texture & feel

SENSORY
Consistency
Lightweight Oil
Scent
Fragrance-Free
Absorption
Instant
Finish
Dewy, Non-Greasy

Bioidentical Hydration

Mimics your skin's natural squalene for instant, deep moisture that feels weightless and natural.

Boosts Active Absorption

Helps other skincare ingredients penetrate more deeply and work more effectively.

Sustainable Sourcing

Derived from renewable sugarcane, saving 2 million sharks per year from liver harvesting.

Microbiome Support

Promotes microbiome diversity for healthier, more resilient skin over time.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

100% squalane contains no retinoids, salicylic acid, or any ingredients contraindicated during pregnancy. Safe for use throughout pregnancy and breastfeeding (avoid applying to areas baby's mouth contacts).

Fungal Acne (Malassezia) Safe

Sugarcane-derived squalane is a hydrocarbon, not a fatty acid. It cannot be metabolized by Malassezia yeast, making it one of the safest oils for fungal acne-prone skin.

Non-Comedogenic

Rated 0-1 on the comedogenic scale. Pure squalane does not clog pores and is suitable for all skin types including acne-prone skin.

Sensitive Skin Approved

Hypoallergenic and dermatologist tested. Research shows squalane is non-irritating even at 100% concentration. Ideal for reactive and sensitive skin types.

Safe with All Actives

Can be layered with retinol, vitamin C, AHAs, BHAs, and niacinamide without any interactions or irritation concerns.

All Ages Safe

Suitable for all ages from babies to elderly. Biossance states it is safe for all ages.

03

Ingredient breakdown

INGREDIENTS

Squalane 100%Proven

A saturated hydrocarbon that mimics squalene, a natural component of human sebum. Derived from sustainable Brazilian sugarcane through bio-fermentation, this stable, pure form provides exceptional moisturizing properties without oxidation concerns.

  • Mechanism: Creates a protective barrier that prevents transepidermal water loss (TEWL) while allowing skin to breathe
  • Research: Studies show squalane is non-irritating even at 100% concentration (Cosmetic Ingredient Review)
  • Bioidentical: Mirrors the squalene naturally produced by your skin, which decreases with age after mid-20s
  • Stability: Hydrogenated form has a long shelf life and won't oxidize like squalene
Clinical studies show 100% of subjects had increased cell renewal rate after 5 weeks of use.

1 ingredient

Squalane

FREE FROM: Parabens, Sulfates, Phthalates, Fragrances, Essential Oils, Mineral Oil, Silicones, PEGs, Formaldehyde, Synthetic Dyes, Animal-Derived Ingredients, and 2,000+ potentially toxic or irritating ingredients banned by Biossance.
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Serum
4
Eye Cream
5
Moisturizer
6
Squalane Oil

Apply as the last step to lock in all previous products. For oily skin, apply to damp skin. Can also be mixed with moisturizer or used alone.

05

How to use

HOW TO USE
1

For Face

Warm 2-3 drops between palms. Pat gently onto face, neck, and décolleté after serums and moisturizer. For oily skin, apply to damp skin for lighter absorption.

2

For Body

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on dry areas like elbows, knees, and heels.

3

For Hair

Warm a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz. Can also be used as a scalp treatment.

4

For Lips

Apply a thin layer to lips to combat dryness and prep for color. Works great as an overnight lip treatment.

06

Who is it for?

WHO

Perfect for you if:

  • You want a single multi-purpose oil for face, body, and hair
  • You have dry, dehydrated, or aging skin
  • You need a fungal acne-safe moisturizing option
  • You're pregnant or breastfeeding and want safe hydration
  • You have sensitive or reactive skin
  • You want to boost absorption of other skincare products
  • You prefer clean, sustainable beauty products
  • You want a fragrance-free option

Consider alternatives if:

  • You're looking for additional active ingredients like vitamin C or retinol
  • You prefer a dropper over a pump dispenser
  • You're on a strict budget (more affordable dupes exist)
  • You want a scented oil experience
  • You need a mattifying finish (this has a dewy finish)
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Lightweight and fast-absorbing. Apply to damp skin for non-greasy hydration. Helps balance oil production without clogging pores.

Dry Skin
Excellent

Provides deep, lasting hydration and locks in moisture. Can be layered generously or mixed with moisturizer for extra nourishment.

Combination Skin
Excellent

Balances well across different face zones. Use sparingly on T-zone and more generously on dry cheeks.

Sensitive Skin
Excellent

Hypoallergenic, fragrance-free, and non-irritating. Single ingredient formula minimizes risk of reactions.

Acne-Prone Skin
Excellent

Non-comedogenic (rating 0) and fungal acne safe. Won't clog pores or feed Malassezia yeast.

Mature Skin
Excellent

Replenishes squalene that skin loses with age. Promotes cell renewal and improves skin elasticity.

08

Results timeline

WEEK 5+
Immediately

Instant Hydration

Skin feels instantly hydrated, soft, and smooth. Absorbs quickly without leaving a greasy residue. Provides immediate comfort to dry, tight skin.

95% noticed instant hydration
Week 1

Improved Softness

Skin appears softer and smoother. Rough patches begin to improve. Overall texture feels more refined and supple.

95% noticed softer skin
Week 2

Enhanced Nourishment

Skin is noticeably more nourished and hydrated. Moisture barrier is strengthened. Dullness begins to diminish.

93% noticed improved hydration
Week 5+

Cell Renewal Boost

Increased cell renewal rate accelerates skin turnover by 5 days compared to untreated skin. Skin looks healthier and more radiant.

100% showed increased cell renewal
09

Ratings by platform

2K+ REVIEWS
Biossance.com
4.8
Rating
830+
Reviews
Main complaint: Price point is high compared to similar squalane oils
Sephora
4.3
Rating
500+
Reviews
Main complaint: Pump dispenses more product than needed
Amazon
4.6
Rating
1,200+
Reviews
Main complaint: Some concerns about product authenticity from third-party sellers
Cult Beauty
4.5
Rating
150+
Reviews
Main complaint: May feel slightly heavy for very oily skin types
10

Pros & cons

BALANCED

Praised

  • Ultra-lightweight and fast-absorbing
  • Versatile: works on face, body, hair, and lips
  • Single, pure ingredient with no additives
  • Safe for all skin types including sensitive
  • Fungal acne and pregnancy safe
  • Sustainable, shark-friendly sourcing
  • Large 100ml bottle lasts a long time
  • Convenient pump dispenser
  • No fragrance or irritating ingredients
  • Visible results backed by clinical studies

Criticized

  • Higher price point than drugstore alternatives
  • Pump can dispense too much product
  • No additional active ingredients
  • Dewy finish may not suit those wanting matte
  • Plastic packaging (though recyclable)
  • Some prefer dropper for precise application
11

Budget-friendly alternatives (dupes)

DUPES
100% Match
100% Plant-Derived Squalane
$7.90
Budget Pick

Identical single-ingredient formula at a fraction of the price. Comes with dropper instead of pump. Source may vary (not specified as sugarcane). Slightly thicker texture.

100% Match
Squalane Oil
$8.00
Budget Pick

Same 100% squalane formula. Olive-derived (slightly thicker texture). Smaller 13ml bottle but excellent value. Glass dropper packaging.

100% Match
Squalane Oil 100% Pure
$14.00
Similar Price

Olive-derived squalane with medium-weight texture. 2oz bottle with bamboo dropper. Over 5,000 reviews on Amazon. Works well as makeup primer too.

100% Match
Squalane Facial Oil
$12.99
Budget Pick

Sugarcane-derived like Biossance. Ultra-light "dry oil" texture that sinks in quickly. Clinical-grade formula. May not be hydrating enough for very dry skin.

12

Comparison with competitors

SIDE-BY-SIDE
100% Plant-Derived Squalane
Key Ingredient 100% Plant-Derived Squalane
Size 30ml / 1oz
Price per oz $7.90/oz
Packaging Dropper Bottle
Texture Medium-Weight
Fungal Acne Safe Yes
Squalane Oil
Key Ingredient 100% Olive-Derived Squalane
Size 13ml / 0.44oz
Price per oz $18.18/oz
Packaging Glass Dropper
Texture Slightly Thicker
Fungal Acne Safe Yes
Squalane Oil 100% Pure
Key Ingredient 100% Olive-Derived Squalane
Size 60ml / 2oz
Price per oz $7.00/oz
Packaging Bamboo Dropper
Texture Medium-Weight
Fungal Acne Safe Yes
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening. Squalane is highly stable and resistant to oxidation.

Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required. Keep bottle closed when not in use.

Packaging

Recyclable pump bottle. Once empty, dispose of pump and rinse bottle for curbside recycling. Outer carton is FSC-certified sugarcane paper.

Travel Friendly

100ml size exceeds TSA carry-on limits. Travel size (30ml) available separately for air travel. Pump bottle is spill-resistant.

13

Frequently asked questions

FAQ

Yes, absolutely. This product contains only 100% pure squalane with no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients that are contraindicated during pregnancy. Squalane is considered completely safe for use throughout pregnancy and breastfeeding. The only precaution: avoid applying to areas that may come in contact with baby's mouth while nursing.

Yes, this is one of the safest oils for fungal acne-prone skin. Sugarcane-derived squalane is a hydrocarbon (made only of carbon and hydrogen), not a fatty acid or triglyceride. Malassezia yeast cannot metabolize squalane, making it completely safe. In fact, dermatologists often recommend squalane as one of the few oils that won't trigger fungal acne flares.

Yes, squalane is compatible with all actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. It has no pH concerns or interaction issues. In fact, applying squalane after these actives can help seal them in, reduce irritation, and enhance their absorption. It's an excellent "finishing" product for any routine.

This squalane oil works excellently for all skin types: dry (deep hydration), oily (apply to damp skin for lightweight moisture), combination (adjust amount by zone), sensitive (hypoallergenic single ingredient), acne-prone (non-comedogenic), and mature (replaces naturally declining squalene). Its versatility is one of its greatest strengths.

Instant results: 95% of users feel immediately hydrated skin. Week 1: Skin feels softer and smoother. Week 2: 93% notice improved nourishment and hydration. Week 5+: Clinical studies show 100% of users experienced increased cell renewal rate, with skin turnover accelerating by 5 days.

Apply as your last step (after moisturizer) to seal in all previous products. The order is: Cleanser → Toner → Serum → Eye Cream → Moisturizer → Squalane Oil. You can also mix a few drops into your moisturizer, use it alone on damp skin, or apply it any time your skin needs extra hydration.

No, squalane has a comedogenic rating of 0-1, meaning it is non-comedogenic and will not clog pores. It's one of the few oils recommended for acne-prone skin. Biossance's formula is dermatologist tested, hypoallergenic, and specifically designed to be safe for all skin types including acne-prone.

The product has a PAO (Period After Opening) of 12 months. Squalane is the hydrogenated, stable form of squalene, which means it's highly resistant to oxidation and has a long shelf life. Store in a cool, dry place away from direct sunlight for best results.

— Skincarisma verdict
4.6 / 5 ★★★★★

Verdict: Biossance 100% Squalane Oil is a premium, sustainably-sourced hydration powerhouse that delivers on its promises. Its single-ingredient purity makes it ideal for sensitive skin, fungal acne sufferers, and pregnant/breastfeeding individuals. While budget alternatives like The Ordinary offer similar formulas at lower prices, Biossance's ultra-lightweight sugarcane-derived texture, convenient pump packaging, and commitment to saving 2 million sharks annually justify the premium for those who value clean beauty and sustainability. A versatile must-have for any skincare routine.

Browse related

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

Awesome, I Understand!

Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

Awesome, I Understand!

Notable Effects & Ingredients

question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

Awesome, I Understand!

Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
oily-skin Oily/Acne-Prone Skin
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

Awesome, I Understand!

Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
100%

Product ingredient list

Showing first 5 of 1 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 A
Squalane
Skin Conditioning, Emollient, Hair Conditioning, Refatting
Hydrating