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24/7 Colostrum Pore Defense Ampoule

24/7 Colostrum Pore Defense Ampoule

Product Description

Product overview

Made in Various INTERNATIONAL

A next-generation spray-type ampoule mist featuring PIXCELL BIOM™ probiotic complex with 5 types of ferment lysates, colostrum proteins, and hyaluronic acid. Delivers instant hydration, pore-minimizing effects, and a glass-skin finish anytime, anywhere.

Dermatologically Tested Fragrance-Free No Artificial Colorants Alcohol-Free 5 Probiotic Ferments Clinically Tested
Pregnancy
Yes
Fungal Acne
No
Comedogenic
1/5
Size
55ml
Format
Spray Mist
Key Active
PIXCELL BIOM™
Colostrum
7,500ppm
Ferments
5 Types
Real reviews · YouTube Shorts
Why it's different

PIXCELL BIOM™ Complex

Proprietary probiotic blend with 90% lactic acid bacteria to strengthen skin barrier and balance microbiome.

01

Texture & feel

SENSORY
Consistency
Fine Mist
Scent
Fragrance-Free
Absorption
Instant
Finish
Dewy Glow

PIXCELL BIOM™ Complex

Proprietary probiotic blend with 90% lactic acid bacteria to strengthen skin barrier and balance microbiome.

Colostrum Proteins

Nutrient-rich growth factors and proteins that promote skin firmness, elasticity, and natural healing.

Glass Skin Finish

Creates a poreless, luminous complexion instantly — perfect before, during, or after makeup application.

Travel-Ready Format

Compact 55ml spray bottle fits in any bag for on-the-go hydration and pore care throughout the day.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

Free from retinoids, salicylic acid, hydroquinone, and chemical sunscreens. Contains colostrum (milk derivative) — consult doctor if you have dairy concerns.

Not Fungal Acne (Malassezia) Safe

Contains multiple fermented ingredients (Bifida, Lactobacillus, Saccharomyces) and milk lipids that may feed malassezia yeast. Avoid if prone to fungal acne.

Low Comedogenic Risk

Rating 1/5. Lightweight, oil-free formula is unlikely to clog pores. No heavy oils or pore-blocking silicones.

Dermatologically Tested

Clinically proven non-irritating formula. Suitable for sensitive skin, but patch test recommended for very reactive skin types.

03

Ingredient breakdown

INGREDIENTS

Bifida Ferment Lysate 3.6%Proven

Probiotic-derived ingredient that strengthens the skin barrier, reduces sensitivity, and optimizes moisture retention by supporting the skin's natural microbiome.

  • Study: 2023 in vitro study showed effectiveness in reducing acne and improving skin barrier function
  • Mechanism: Produces metabolites that protect skin from environmental stressors
Also found in premium products like Lancôme Advanced Génifique and Estée Lauder Advanced Night Repair

Lactobacillus Ferment Lysate 3.6%Proven

Probiotic lysate that balances the natural skin microbiome, prevents harmful bacterial growth, and helps maintain healthy, resilient skin.

  • Function: Produces antimicrobial peptides that protect against pathogens
  • Benefit: Supports skin barrier integrity and reduces inflammation

Colostrum 7,500ppmPromising

Protein and antibody-rich "first milk" containing growth factors, cytokines, and exosomes that stimulate collagen synthesis and protect against oxidative stress.

  • Components: Contains IgG antibodies, lactoferrin, and growth factors (IGF, TGF)
  • Benefits: Improves moisture, promotes wound healing, inhibits melanin production
Derived from bovine milk — not suitable for those with severe dairy allergies

Hyaluronic Acid UndisclosedProven

Gold-standard humectant that attracts and retains moisture, plumping skin and reducing the appearance of fine lines and enlarged pores.

  • Capacity: Can hold up to 1000x its weight in water
  • Clinical: Product showed 97.2% hydration improvement after single use in clinical trials

Panthenol (Pro-Vitamin B5) UndisclosedProven

Deeply penetrating moisturizer that soothes irritation, supports skin barrier repair, and improves skin elasticity.

  • Function: Converts to pantothenic acid in skin to aid cell regeneration
  • Benefit: Calms inflammation and accelerates wound healing

Adenosine UndisclosedProven

Anti-aging powerhouse approved by Korean FDA for wrinkle improvement. Promotes collagen production and improves skin elasticity.

  • Mechanism: Stimulates fibroblast activity for increased collagen synthesis
  • Benefit: Helps tighten enlarged pores and smooth skin texture

36 ingredients

Water, Propanediol, Bifida Ferment Lysate (3.6%), Lactobacillus Ferment Lysate (3.6%), Dipropylene Glycol, Pentylene Glycol, Butylene Glycol, Lactococcus Ferment Lysate, Pichia Ferment Lysate Filtrate, Saccharomyces Ferment Lysate Filtrate, 1,2-Hexanediol, Colostrum (7,500ppm), Chlorella Vulgaris Extract, Xylitol, Vincetoxicum Atratum Extract, Althaea Rosea Flower Extract, Hyaluronic Acid, Milk Lipids, Betaine, Panthenol, Glucose, Glycerin, Fructooligosaccharides, Fructose, Ethylhexylglycerin, Diphenyl Dimethicone, Adenosine, Triethylhexanoin, Sodium Citrate, Sodium Phytate, Citric Acid, Hydrogenated Lecithin, Beta-Glucan, Tocopherol, Magnesium Chloride, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

FREE FROM: Fragrance, Artificial Colorants, Drying Alcohol, Parabens, Sulfates, Mineral Oil, Harsh Preservatives
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
This Ampoule
4
Serum
5
Moisturizer
6
Sunscreen

Use after toner as a hydrating ampoule, or spray over makeup anytime for a dewy glass-skin finish. Can also be used as a makeup setting spray.

05

How to use

HOW TO USE
1

Before Makeup

After cleansing and toning, spray directly onto face from 15-20cm away. Pat gently to aid absorption. Creates a hydrated base for flawless makeup application.

2

After Makeup

Spray diagonally to allow fine particles to fall indirectly on your face. This sets makeup with a natural, dewy glow without disturbing your base.

3

Throughout the Day

Use whenever skin feels dry or needs a refresh. The fine mist penetrates without tapping, revitalizing skin and reducing the appearance of oiliness and enlarged pores.

06

Who is it for?

WHO

Perfect for you if:

  • You want a portable, on-the-go hydration solution
  • You struggle with enlarged pores and excess sebum
  • You want a glass-skin finish over or under makeup
  • You have dehydrated or combination skin
  • You prefer probiotic-based skincare for barrier support
  • You need a multitasking product (primer, mist, setting spray)

Consider alternatives if:

  • You are prone to fungal acne (malassezia folliculitis)
  • You have severe dairy or milk allergies
  • You prefer fragrance-free products without any fermented ingredients
  • You need very heavy, rich hydration for extremely dry skin
  • You are sensitive to probiotic/fermented skincare
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Oil-free formula controls excess sebum and minimizes pore appearance without adding shine. Clinical tests show 90% sebum improvement.

Dry Skin
Good

Provides instant hydration boost with 97.2% improvement. Lightweight formula may need a richer moisturizer on top for very dry skin.

Combination Skin
Excellent

Balances hydration and oil control across different face zones. Perfect for T-zone oiliness with dry cheeks.

Sensitive Skin
Good

Dermatologically tested non-irritating. Fragrance-free and alcohol-free. Patch test recommended for very reactive skin.

Acne-Prone Skin
Moderate

Low comedogenic rating (1/5), but contains fermented ingredients. Not recommended for fungal acne. Good for bacterial acne types.

08

Results timeline

4-8 WEEKS
Immediate

Instant Hydration & Glow

Fine mist delivers immediate moisture boost with visible dewy, glass-skin finish. Pores appear instantly smoother and skin feels refreshed.

97.2% hydration improvement after single use
1-2 Weeks

Improved Skin Texture

Consistent use leads to smoother skin texture, reduced roughness, and better makeup application. Skin barrier feels stronger and more resilient.

95% improvement in pore elasticity
4-8 Weeks

Visible Pore Refinement

Long-term pore tightening effects become noticeable. Sebum production is better regulated, and skin maintains balanced hydration throughout the day.

90% improvement in sebum control
09

Ratings by platform

1K+ REVIEWS
YesStyle
4.6
Rating
325+
Reviews
Main complaint: Some users wish the bottle was larger for the price
Amazon
4.4
Rating
150+
Reviews
Main complaint: Spray nozzle could be finer for more even application
Olive Young
4.7
Rating
500+
Reviews
Main complaint: Product popularity leads to frequent stock shortages
Brand Website
4.8
Rating
200+
Reviews
Main complaint: May feel slightly tacky if over-applied in humid weather
10

Pros & cons

BALANCED

Praised

  • Instant hydration with visible glass-skin glow
  • Portable size perfect for travel and touch-ups
  • Works beautifully under and over makeup
  • No artificial fragrance or colorants
  • Probiotic formula supports skin barrier
  • Clinically proven hydration and pore benefits
  • Lightweight, non-greasy formula absorbs quickly
  • Multifunctional: primer, ampoule, and setting spray

Criticized

  • Not suitable for fungal acne sufferers
  • 55ml bottle may run out quickly with daily use
  • Contains dairy-derived colostrum ingredient
  • Premium price point compared to basic mists
  • Fermented ingredients not for everyone
  • May feel slightly tacky if over-applied
11

Budget-friendly alternatives (dupes)

DUPES
85% Match
Madagascar Centella Poremizing Fresh Ampoule
$9.50
Budget Pick

Focuses on pore care with 50% Centella and 9 peptides. No ferments or colostrum. Fungal acne safe. Dropper format instead of spray mist.

70% Match
The Niacinamide 15 Serum
$16.00
Budget Pick

Targets pores and sebum with 15% niacinamide + zinc. Different mechanism (no probiotics). Fungal acne safe. Dropper serum, not mist format.

65% Match
Numbuzin No. 3 Pore Reset Ampoule Shot
$22.00
Similar Price

Retinol-based pore care with adenosine. Different approach using vitamin A derivatives. Not pregnancy safe. More anti-aging focused.

12

Comparison with competitors

SIDE-BY-SIDE
Madagascar Centella Poremizing Fresh Ampoule
Key Ingredients 50% Centella + 9 Peptides
Size 30-100ml
Format Dropper
Fungal Acne Safe Yes
Pregnancy Safe Yes
Best For Calming + Pores
The Niacinamide 15 Serum
Key Ingredients 15% Niacinamide + Zinc
Size 20ml
Format Dropper
Fungal Acne Safe Yes
Pregnancy Safe Yes
Best For Sebum + Brightening

Numbuzin No. 3 Pore Reset Ampoule

Key Ingredients Retinol + Adenosine
Size 30ml
Format Dropper
Fungal Acne Safe Check List
Pregnancy Safe No (Retinol)
Best For Anti-aging + Pores
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store in a cool, dry place away from direct sunlight. Refrigeration not required but can enhance refreshing feeling.

Packaging

Opaque spray bottle with fine mist nozzle for even, hygienic application

Travel Friendly

Yes — 55ml is under the 100ml TSA/airport limit for carry-on liquids

13

Frequently asked questions

FAQ

Yes, this product is generally considered safe during pregnancy and breastfeeding. It does not contain retinoids, salicylic acid, hydroquinone, or chemical sunscreens — the main ingredients to avoid during pregnancy. However, it does contain colostrum (a bovine milk derivative). If you have concerns about dairy-derived ingredients, consult your healthcare provider before use.

No, this product is NOT fungal acne safe. It contains multiple fermented ingredients (Bifida Ferment Lysate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Pichia Ferment Lysate Filtrate, Saccharomyces Ferment Lysate Filtrate) and milk lipids that may feed malassezia yeast and potentially worsen fungal acne. If you're prone to fungal acne, consider alternatives like SKIN1004 Madagascar Centella Poremizing Ampoule or COSRX Niacinamide 15 Serum instead.

Yes, this ampoule is compatible with most active ingredients including retinol, vitamin C, AHAs, and BHAs. Since it focuses on hydration and barrier support with probiotics, it can actually help buffer potential irritation from strong actives. For best results, apply water-based actives first, then use this ampoule mist to lock in hydration. If using with retinol, apply the ampoule first to create a hydration buffer.

This ampoule is best suited for oily, combination, and dehydrated skin types. It excels at controlling excess sebum while providing hydration — perfect for those with large pores and oily T-zones. It also works well for normal skin seeking a glass-skin finish. Dry skin types can use it but may need a heavier moisturizer on top. Sensitive skin can generally tolerate it (it's dermatologically tested), but patch testing is recommended.

Immediate results include instant hydration (clinically shown at 97.2% improvement) and visible dewy glow. After 1-2 weeks of consistent use, expect smoother skin texture and improved makeup application. Visible pore refinement and long-term sebum control typically appear after 4-8 weeks. Clinical trials showed 95% improvement in pore elasticity and 90% improvement in sebum control with regular use.

This versatile product can be used at multiple points in your routine: (1) After cleansing and toning as a hydrating ampoule — spray directly on face before serums/moisturizer. (2) Before makeup as a hydrating primer for a smooth base. (3) After makeup as a setting spray for a dewy finish. (4) Throughout the day whenever skin needs a hydration refresh. It absorbs instantly, so no waiting time is needed between applications.

This ampoule has a low comedogenic rating of 1/5, meaning it is unlikely to clog pores. The formula is oil-free and contains no heavy occlusives or known pore-clogging ingredients. It's actually designed to minimize pore appearance. However, everyone's skin is different — if you're extremely prone to clogged pores, patch test first on a small area before full-face application.

The product has a PAO (Period After Opening) of 12 months. Once opened, use within one year for optimal efficacy. Store in a cool, dry place away from direct sunlight. The 55ml size typically lasts 2-3 months with regular daily use (2-3 sprays per application, 2-3 times daily). Check for any changes in color, texture, or smell — discontinue use if the product appears altered.

— Skincarisma verdict
4.5 / 5 ★★★★★

Verdict: The PURCELL 24/7 Colostrum Pore Defense Ampoule is an innovative K-beauty multitasker that delivers on its promises of instant hydration, pore refinement, and glass-skin glow. The PIXCELL BIOM™ probiotic complex with 5 ferment lysates and colostrum proteins offers unique barrier-strengthening benefits backed by clinical data. Perfect for oily and combination skin types seeking a portable, versatile product that works as ampoule, primer, and setting spray. The main limitation is that it's not suitable for fungal acne sufferers due to its fermented ingredients. At ~$35 for 55ml, it's a premium investment, but the clinical efficacy (97.2% hydration, 95% pore elasticity improvement) and multi-use functionality justify the price for the right skin type.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 5 ingredient(s):
Adenosine Citric Acid Beta-Glucan Tocopherol Hyaluronic Acid
brightening Brightening from 3 ingredient(s):
Citric Acid Hyaluronic Acid Glycerin
wound Promotes Wound Healing from 6 ingredient(s):
Panthenol Adenosine Citric Acid Tocopherol Hyaluronic Acid Glycerin
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
5
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
65% 34%

Product ingredient list

Showing first 5 of 35 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Propanediol
Solvent, Viscosity Controlling, Viscosity Decreasing Agent
1 Unknown
Bifida Ferment Lysate
Skin Conditioning
Hydrating
Irritation
1 Unknown
Lactobacillus Ferment Lysate
Skin Conditioning
1 A
Dipropylene Glycol
Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling
1 A
Pentylene Glycol
Solvent, Skin Conditioning
VIEW ALL INGREDIENTS