5% Potassium Azeloyl Diglycinate + 2% Niacinamide + Hyaluronic Acid Serum
5% Potassium Azeloyl Diglycinate + 2% Niacinamide + Hyaluronic Acid Serum
Product Description
Product overview
A gentle yet powerful clarifying serum featuring 5% Potassium Azeloyl Diglycinate (a next-generation azelaic acid derivative) combined with 2% Niacinamide and Hyaluronic Acid. Designed for sensitive and acne-prone skin, this lightweight formula brightens complexion, reduces blemishes, evens skin tone, and regulates oil production without irritation.
Brightens & Evens Skin Tone
Potassium Azeloyl Diglycinate inhibits tyrosinase enzyme to reduce melanin production, fading dark spots and hyperpigmentation for a more luminous complexion.
Texture & feel
SENSORYBrightens & Evens Skin Tone
Potassium Azeloyl Diglycinate inhibits tyrosinase enzyme to reduce melanin production, fading dark spots and hyperpigmentation for a more luminous complexion.
Controls Sebum Production
Regulates oil secretion without stripping skin, helping to minimize shine and reduce the appearance of enlarged pores for balanced, mattified skin.
Soothes & Calms Redness
Anti-inflammatory properties from PAD, Centella Asiatica, and Allantoin work synergistically to reduce redness, irritation, and sensitivity.
Hydrates Without Heaviness
Hyaluronic Acid and Snail Secretion Filtrate deliver deep hydration while maintaining a lightweight, non-sticky texture perfect for layering.
Safety & compatibility
SAFEContains no retinoids, salicylic acid, hydroquinone, or chemical sunscreens. PAD (azelaic acid derivative) is considered safe for use during pregnancy and breastfeeding. Always consult your healthcare provider.
Free from fatty acids, esters, ferments, and polysorbates that feed malassezia yeast. Verified safe for those prone to fungal acne or pityrosporum folliculitis.
Contains no pore-clogging oils or heavy emollients. Lightweight water-based formula suitable for acne-prone and congestion-prone skin types.
Fragrance-free, alcohol-free, and paraben-free. Contains soothing ingredients like Allantoin and Centella Asiatica to minimize irritation risk.
PAD is gentler than pure azelaic acid and can typically be used alongside Vitamin C, retinoids, and other acids. Start slowly when combining with strong exfoliants.
As with any new skincare product, perform a patch test on a small area before full face application, especially if you have reactive or sensitized skin.
Ingredient breakdown
INGREDIENTSPotassium Azeloyl Diglycinate (PAD) 5%Proven Active
A next-generation, water-soluble derivative of azelaic acid combined with glycine. More stable and gentler than pure azelaic acid while delivering similar brightening, sebum-regulating, and anti-inflammatory benefits.
- Mechanism: Inhibits tyrosinase enzyme to reduce melanin production and brighten skin tone
- Clinical Study: 2012 study showed significant improvement in rosacea symptoms after 28 days of use
- Research: 2010 Thai study demonstrated effectiveness in treating melasma when combined with niacinamide
- Benefit: Normalizes sebum production without drying, ideal for oily and combination skin
Niacinamide (Vitamin B3) 2%Gold Standard
A multitasking skincare superstar with extensive research backing its efficacy for pore refinement, brightening, oil control, and barrier strengthening.
- Pore Reduction: Studies show 2-5% concentration effectively minimizes pore appearance
- Barrier Support: Increases ceramide and fatty acid production in the skin barrier
- Synergy: Works synergistically with PAD to enhance brightening and sebum control
- Anti-Aging: 4% concentration shown to reduce wrinkle depth by 9% after 8 weeks
Sodium Hyaluronate IncludedHydration Hero
A smaller molecular form of hyaluronic acid that penetrates deeper into skin layers, attracting and holding up to 1000x its weight in water for plump, hydrated skin.
- Hydration: Draws moisture from the environment into the skin
- Anti-Aging: Plumps fine lines and improves skin elasticity
- Compatibility: Works well with all skin types and other active ingredients
Centella Asiatica Extract IncludedSoothing
Also known as Cica or Tiger Grass, this botanical extract is renowned for its healing, calming, and antioxidant properties. A K-beauty staple for sensitive and irritated skin.
- Active Compounds: Rich in madecassoside, asiaticoside, and asiatic acid
- Wound Healing: Stimulates collagen synthesis and promotes skin repair
- Anti-Inflammatory: Reduces redness and calms irritated skin
Snail Secretion Filtrate IncludedRepair
A nutrient-rich ingredient containing glycoproteins, hyaluronic acid, and glycolic acid that supports skin repair, hydration, and overall skin health.
- Multi-Function: Provides hydration, promotes healing, and improves texture
- Natural Components: Contains allantoin, elastin, and antimicrobial peptides
- Scar Fading: May help reduce the appearance of acne scars over time
Supporting IngredientsSoothing Complex
Additional skin-caring ingredients that enhance the formula's efficacy and tolerability.
- Allantoin: Promotes skin healing, soothes irritation, and softens skin texture
- Witch Hazel Extract: Natural astringent that tightens pores and reduces inflammation
- Glycerin: Powerful humectant that draws moisture into the skin barrier
12 ingredients
Water, Potassium Azeloyl Diglycinate, Propylene Glycol, Niacinamide, Centella Asiatica Leaf Extract, Snail Secretion Filtrate, Glycerin, Ethylhexylglycerin, Hamamelis Virginiana (Witch Hazel) Leaf Extract, Hydroxyethylcellulose, Sodium Hyaluronate, Allantoin
Where it fits in your routine
ROUTINEApply after water-based toners and essences, before heavier serums, oils, and moisturizers. Can be used both morning and evening.
How to use
HOW TO USECleanse Your Skin
Start with a gentle, pH-balanced cleanser. Pat skin dry or leave slightly damp for better absorption.
Apply Toner (Optional)
If using a hydrating toner or essence, apply first and wait for it to absorb before the serum.
Dispense 2-3 Drops
Pump 2-3 drops onto your fingertips. A little goes a long way with this concentrated formula.
Apply & Press Gently
Spread evenly across face and neck, avoiding the eye area. Gently press into skin until absorbed.
Follow With Moisturizer
Seal in the serum with your favorite moisturizer. In the AM, always finish with SPF 30 or higher.
Who is it for?
WHOPerfect for you if:
- You struggle with oily or combination skin
- You have acne, blemishes, or clogged pores
- You want to fade dark spots or hyperpigmentation
- You have redness, rosacea, or easily irritated skin
- Pure azelaic acid is too harsh for your skin
- You're pregnant or breastfeeding and need safe actives
- You have fungal acne (malassezia folliculitis)
- You want a lightweight, non-greasy formula
Consider alternatives if:
- You need very strong/prescription-level treatment for severe acne
- You prefer cream-based textures over gel serums
- You're looking for intense anti-aging effects (try retinoids)
- You have very dry skin and need heavy occlusives
- You expect overnight dramatic results
- You're allergic to snail secretion or any listed ingredients
Skin type compatibility
SKIN TYPESIdeal match. PAD regulates sebum production while the lightweight gel texture absorbs quickly without adding shine or heaviness.
Balances oily T-zone while providing hydration to drier areas. Non-comedogenic formula works across all face zones.
Fungal acne safe, non-comedogenic (0/5), and helps control oil and blemishes. Safe for breakout-prone skin.
Fragrance-free with soothing ingredients. PAD is gentler than pure azelaic acid. Patch test first if very reactive.
Provides hydration via HA and snail mucin. Layer with a richer moisturizer or facial oil to prevent any dryness.
Niacinamide offers anti-aging benefits. Good for age spots and uneven tone. Pair with dedicated anti-aging products.
Results timeline
WEEK 8-12Initial Adjustment & Hydration Boost
Skin feels softer and more hydrated. Some users may experience minor purging if prone to congestion. Slight improvement in skin texture begins.
70% noticed improved hydrationOil Control & Reduced Shine
Sebum regulation becomes noticeable. Skin appears less shiny throughout the day. Pores may appear refined. Redness starts to calm.
65% noticed reduced oilinessVisible Brightening & Tone Evening
Dark spots begin to fade. Overall complexion looks brighter and more even. Blemishes heal faster with less post-inflammatory hyperpigmentation.
75% noticed brighter skin toneSignificant Transformation
Maximum benefits achieved with consistent use. Hyperpigmentation significantly reduced. Skin appears clearer, smoother, and more radiant overall.
80% saw significant improvementRatings by platform
6K+ REVIEWSPros & cons
BALANCEDPraised
- Gentle formula suitable for sensitive and acne-prone skin
- Pregnancy and breastfeeding safe
- Fungal acne (malassezia) safe and non-comedogenic
- Lightweight, fast-absorbing gel texture
- Effectively controls oil without drying
- Fragrance-free and minimal ingredients (12 total)
- Affordable Filipino brand with quality formulation
- Can be used AM and PM
- Good for layering with other products
Criticized
- Results take time (4-8 weeks for visible changes)
- PAD is less potent than prescription azelaic acid
- Small 30ml bottle may not last long
- Limited availability outside Philippines/Asia
- May not be strong enough for severe hyperpigmentation
- Some users may prefer higher niacinamide percentage
Budget-friendly alternatives (dupes)
DUPESHigher PAD concentration (6% pure PAD). Lightweight gel texture. No niacinamide but pregnancy-safe and fungal acne safe. Hungarian brand with cult following.
Uses pure azelaic acid (10%) instead of PAD derivative. Thicker cream-paste texture that may pill. More potent but potentially more irritating for sensitive skin.
Pure azelaic acid formula at lower price point. Cream texture. Good entry-level option but may be harsher than PAD-based serums for sensitive skin.
Premium formulation with added salicylic acid and licorice root. Better for sensitive skin than most azelaic acids. Higher price point but elegant texture.
Comparison with competitors
SIDE-BY-SIDEDermorepubliq 5% PAD Serum
Storage & shelf life
12 MONTHS12 months after opening. Check for changes in color, smell, or texture before use.
Store in a cool, dry place away from direct sunlight. Keep cap tightly closed. No refrigeration required.
Amber glass bottle with pump dispenser. Protects actives from light degradation and ensures hygienic dispensing.
Yes, 30ml is under 100ml TSA limit. Glass bottle - pack carefully in checked luggage or use protective case.
Frequently asked questions
FAQYes, this serum is considered safe for use during pregnancy and breastfeeding. Potassium Azeloyl Diglycinate (PAD) is a derivative of azelaic acid, which is classified as pregnancy-safe by dermatologists. The formula contains no retinoids, salicylic acid, hydroquinone, or other ingredients contraindicated during pregnancy. However, always consult with your healthcare provider before adding new skincare products to your routine during pregnancy.
Yes, this serum is verified fungal acne safe. The formula is free from fatty acids, fatty alcohols, esters, polysorbates, and fermented ingredients that can feed the malassezia yeast responsible for fungal acne. It's an excellent choice for those prone to pityrosporum folliculitis or who experience breakouts from traditional skincare products.
PAD is gentler than pure azelaic acid and can generally be used alongside other actives. You can use it with Vitamin C (apply Vitamin C in AM, PAD in PM, or vice versa). For retinol, start by alternating nights until your skin adjusts. With AHA/BHA, use them on separate days initially to avoid over-exfoliation. If you experience any irritation, reduce frequency or use products on alternate days.
This serum is excellent for oily, combination, and acne-prone skin types due to its sebum-regulating properties. It's also suitable for sensitive skin thanks to the gentle PAD formula and soothing ingredients. Dry skin types can use it but should follow with a richer moisturizer. It's particularly beneficial for those dealing with hyperpigmentation, redness, rosacea, or uneven skin tone.
Results vary by individual and concern. Improved hydration and smoother texture may be noticed within 1-2 weeks. Oil control typically becomes noticeable around weeks 2-4. For brightening and hyperpigmentation fading, expect to see visible improvements around weeks 4-6, with optimal results at 8-12 weeks of consistent twice-daily use. Patience and consistency are key with any skincare active.
Apply this serum after cleansing and toning, but before heavier serums, moisturizers, and oils. The general rule is thinnest to thickest consistency. Apply to clean, slightly damp skin for better absorption. In your AM routine, always finish with sunscreen. Can be used both morning and evening for best results.
No, this serum has a comedogenic rating of 0/5, meaning it is non-comedogenic and should not clog pores. The lightweight, water-based formula contains no heavy oils or pore-clogging ingredients. It's actually beneficial for congested skin as PAD helps regulate sebum production and clear out pores. Safe for acne-prone and breakout-prone skin.
The serum has a Period After Opening (PAO) of 12 months. With twice-daily use, a 30ml bottle typically lasts 2-3 months. Store in a cool, dry place away from direct sunlight. The amber glass bottle helps protect the formula from light degradation. Discard if you notice any changes in color, smell, or texture.
Verdict: Dermorepubliq's 5% Potassium Azeloyl Diglycinate Serum is an excellent, well-formulated option for those seeking a gentle yet effective brightening and clarifying treatment. The combination of PAD, niacinamide, and hydrating ingredients delivers multiple benefits without irritation. Its fungal acne safe and pregnancy-safe status makes it accessible to a wide audience. While not as potent as prescription azelaic acid, the trade-off is a much gentler experience suitable for daily use. An impressive affordable option from a Filipino brand that proves effective skincare doesn't have to break the bank.Highly recommended for oily, acne-prone, or sensitive skin types seeking to address hyperpigmentation and excess oil.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 0 |
Potassium Azeloyl Diglycinate
Skin Conditioning
|
Redness
Irritation
Dark Spots
|
|
| 3 |
Propylene Glycol
Solvent, Skin Conditioning, Fragrance, Humectant, Viscosity Controlling, Viscosity Decreasing Agent, Skin-Conditioningagent - Miscellaneous
|
Hydrating
|
|
| 1 |
Niacinamide
Skin Conditioning, Hair Conditioning, Smoothing
|
Promotes Wound Healing
Redness
Irritation
Dark Spots
Pores
|
|
| 1 |
Centella Asiatica Leaf Extract
Skin Conditioning
|
Promotes Wound Healing
|




