Skip to content

Active Serum

Active Serum

Product Description

Product overview

Made in Various INTERNATIONAL

A powerful, fast-acting botanical serum that combines natural forms of glycolic, lactic, and salicylic acids to visibly reduce fine lines, even skin tone, and clear blemish-prone skin. This clinically-proven multi-tasking formula delivers results within days, leaving skin smooth, bright, and refreshed.

Clinically Proven Paraben-Free Cruelty-Free Fragrance-Free Oil-Free Dermatologist Recommended
Pregnancy
Caution
Fungal Acne
Yes
Comedogenic
1/5
Size
1 fl oz / 30ml
Form
Liquid Serum
Target
Acne, Aging, Tone
Use
AM or PM
Active %
12% Acids
Real reviews · YouTube Shorts
Why it's different

Triple-Acid Exfoliation

Botanical-derived glycolic, lactic, and salicylic acids work synergistically to resurface skin at multiple levels.

01

Texture & feel

SENSORY
Consistency
Lightweight Liquid
Scent
Light Herbal/Menthol
Absorption
Instant
Finish
Cooling Tingle

Triple-Acid Exfoliation

Botanical-derived glycolic, lactic, and salicylic acids work synergistically to resurface skin at multiple levels.

Brightening Complex

Arbutin and mushroom extract help fade dark spots and even out skin tone for a luminous complexion.

Pore-Clearing Action

Willow bark extract (natural BHA) penetrates deep into pores to clear congestion and prevent breakouts.

Fast-Acting Formula

Clinically proven to show visible results within days, not weeks. Most users notice improvement quickly.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding

Contains willow bark (salicylate) and arbutin. Consult your healthcare provider before use during pregnancy or nursing. Some dermatologists advise caution.

Fungal Acne (Malassezia) Safe

Oil-free, no fatty acids, no ferments. This formula does not feed malassezia yeast and is safe for fungal acne-prone skin.

Low Comedogenic Rating

Rated 1/5 for pore-clogging potential. Lightweight, oil-free formula is unlikely to cause breakouts or congestion.

Sensitive Skin Note

Contains alcohol denat. and menthol which may cause tingling. Start with every other day use and always follow with SPF.

03

Ingredient breakdown

INGREDIENTS

Sugar Cane Extract 8%Proven

Natural source of glycolic acid, the smallest AHA molecule that penetrates deeply to exfoliate the stratum corneum and boost cell turnover.

  • Function: Desquamation agent that encourages gentle exfoliation
  • Benefit: Smooths texture, fades discoloration, stimulates collagen
Glycolic acid is the gold standard AHA for anti-aging and skin brightening.

Bilberry Extract 2%Proven

Natural source of lactic acid from Vaccinium Myrtillus fruit. Rich in antioxidants that gently exfoliate while promoting healthy blood flow.

  • Function: AHA exfoliant with antioxidant properties
  • Benefit: Softens fine lines, increases collagen production, calms skin

Willow Bark Extract 2%Proven

Natural source of salicylic acid (BHA) from Salix Alba bark. Oil-soluble to penetrate deep into pores and clear congestion.

  • Function: BHA that exfoliates inside the pore lining
  • Benefit: Unclogs pores, reduces inflammation, prevents breakouts
Salicylates should be used with caution during pregnancy. Consult your doctor.

Arbutin —Proven

Plant-derived brightening agent that inhibits tyrosinase enzyme to reduce melanin production and fade hyperpigmentation.

  • Function: Tyrosinase inhibitor for skin brightening
  • Benefit: Fades dark spots, evens skin tone, reduces post-acne marks

Mushroom Extract —Promising

Polyporus Umbellatus extract rich in fatty acids that supports skin barrier function and promotes a radiant complexion.

  • Function: Skin conditioning and barrier support
  • Benefit: Improves moisture retention, boosts collagen, calms inflammation

13 ingredients

Water/Aqua/Eau, Glycerin, Butylene Glycol, Alcohol Denat., Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Vaccinium Myrtillus Fruit/Leaf Extract, Triethanolamine, Salix Alba (Willow) Bark Extract, Glyceryl Polyacrylate, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol

FREE FROM: Parabens, Phthalates, Sulfates, Fragrance, Oils, Silicones, Retinoids, Hydroquinone, Dyes, Gluten
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Active Serum
4
Treatment
5
Moisturizer
6
Sunscreen

Apply after cleansing/toning, before heavier treatments. Do not use with retinol or other AHA/BHA products on the same night.

05

How to use

HOW TO USE
1

Cleanse Your Skin

Start with clean, dry skin. Use a gentle cleanser to remove makeup and impurities.

2

Apply 3-4 Drops

Dispense drops onto palm or fingertips. A little goes a long way with this concentrated formula.

3

Dab and Smooth

Gently press and smooth evenly over face and neck. Avoid immediate eye area.

4

Allow to Absorb

Expect a cool tingling sensation that dissipates within a few minutes. This indicates the serum is working.

5

Follow with Moisturizer

Layer with your favorite moisturizer. In AM, always finish with SPF 30+.

06

Who is it for?

WHO

Perfect for you if:

  • You struggle with acne, breakouts, or congested pores
  • You want to fade dark spots and even skin tone
  • You're looking to reduce fine lines and wrinkles
  • You have oily or combination skin
  • You want multi-tasking anti-aging benefits
  • You prefer botanical-based actives over synthetic

Consider alternatives if:

  • You're pregnant or breastfeeding (consult doctor first)
  • You have extremely sensitive or reactive skin
  • You're allergic to aspirin or salicylates
  • You're already using strong retinoids daily
  • You prefer fragrance-free products with no menthol
  • You're on a tight budget (this is a premium product)
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Oil-free, lightweight formula absorbs instantly. BHA helps control excess sebum and clear pores.

Combination Skin
Excellent

Balances oily T-zone while providing hydration. Works across different facial zones effectively.

Acne-Prone
Excellent

Triple-acid formula targets breakouts at every level. Non-comedogenic and fungal acne safe.

Dry Skin
Moderate

Contains alcohol which may be drying. Always layer with rich moisturizer. Start every other day.

Sensitive Skin
Moderate

Menthol tingling may be intense. Patch test first. Mix with Hydra-Cool Serum to buffer if needed.

Mature Skin
Good

Excellent for fine lines, wrinkles, and age spots. Glycolic acid boosts collagen production effectively.

08

Results timeline

MONTH 2-3
Days 1-3

Immediate Clarity

Skin feels smoother and looks more refined. Active breakouts begin calming down. Initial brightness boost visible.

78% noticed improvement
Week 1-2

Visible Texture Improvement

Pores appear smaller and cleaner. Skin texture becomes noticeably smoother. Breakouts reduce in frequency.

85% saw clearer skin
Week 3-4

Tone Evening

Dark spots and post-acne marks begin to fade. Overall skin tone appears more even and luminous.

72% reported brighter skin
Month 2-3

Significant Transformation

Fine lines visibly reduced. Hyperpigmentation significantly faded. Skin looks healthier and more youthful overall.

68% saw anti-aging results
09

Ratings by platform

7K+ REVIEWS
Amazon
4.5
Rating
3,500+
Reviews
Main complaint: High price point for bottle size
Dermstore
4.7
Rating
1,200+
Reviews
Main complaint: Tingling sensation too intense for some
LovelySkin
4.8
Rating
800+
Reviews
Main complaint: Alcohol content can be drying for some
Brand Website
4.9
Rating
2,000+
Reviews
Main complaint: Wish there was a larger size option
10

Pros & cons

BALANCED

Praised

  • Fast-acting results visible within days
  • Multi-tasking: acne, aging, and brightening in one
  • Lightweight, absorbs instantly
  • A little goes a long way - bottle lasts 6+ months
  • Clinically proven with independent studies
  • Beloved by dermatologists and estheticians
  • Oil-free and fungal acne safe
  • Works for all ages and most skin types

Criticized

  • High price point ($92+ for 1 oz)
  • Intense tingling may be uncomfortable
  • Contains alcohol denat. (potentially drying)
  • Small bottle size for the cost
  • Not pregnancy-safe without doctor approval
  • May cause purging initially
  • Menthol can irritate very sensitive skin
11

Budget-friendly alternatives (dupes)

DUPES
75% Match
Skin Perfecting 2% BHA Liquid Exfoliant
$35.00
Budget Pick

Contains 2% salicylic acid without AHAs. Excellent for pore-clearing but lacks glycolic/lactic acid for anti-aging benefits. No arbutin for brightening.

65% Match
AHA 30% + BHA 2% Peeling Solution
$9.00
Budget Pick

Much higher acid concentration but used only as weekly peel (10 min). Not daily-use like Active Serum. More intense, requires careful introduction.

70% Match
Prism 12% AHA + 3% BHA Exfoliating Glow Serum
$54.00
Similar Price

Similar acid percentages with fruit-derived AHAs. Clean formula, no alcohol. Lacks willow bark specifically and arbutin brightening complex.

60% Match
Ready Steady Glow Daily AHA Tonic
$38.00
Budget Pick

Lactic acid-focused toner with azelaic acid for brightening. Gentler formula, good for sensitive skin. Less potent overall but daily-use friendly.

12

Comparison with competitors

SIDE-BY-SIDE
Blemish + Age Defense
Key Actives 2% Dioic + 0.3% LHA + 1.5% Salicylic
Brightening Dioic Acid Only
Size 30ml / 1 fl oz
Best For Adult Acne + Aging
Use Daily (Twice Daily)
T.L.C. Framboos Glycolic Night Serum
Key Actives 12% AHA/BHA Blend
Brightening Raspberry Extract
Size 30ml / 1 fl oz
Best For Texture + Pores
Use Nightly
BHA 9 Treatment
Key Actives 2% Salicylic Acid Only
Brightening None
Size 118ml / 4 fl oz
Best For Pores + Acne Only
Use Daily (1-2x)
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store in cool, dry place away from direct sunlight. Keep tightly closed after use.

Packaging

Dark glass dropper bottle to protect active ingredients from light degradation

Travel Friendly

Yes, 30ml/1oz is under TSA liquid limit for carry-on luggage

13

Frequently asked questions

FAQ

Active Serum contains willow bark extract (a natural salicylate) and arbutin, which some healthcare providers recommend avoiding during pregnancy and breastfeeding. While the brand states it's "suitable for new moms," we recommend consulting your doctor or dermatologist before use during pregnancy or while nursing to ensure safety for your specific situation.

Yes! Active Serum is fungal acne safe. The formula is oil-free, contains no fatty acids, fermented ingredients, or esters that feed malassezia yeast. The lightweight, water-based formula makes it an excellent choice for those prone to fungal acne or pityrosporum folliculitis.

Do not use Active Serum on the same night as retinol or other AHA/BHA products to avoid over-exfoliation and irritation. You can alternate nights (Active Serum one night, retinol the next). Vitamin C can be used in the morning while Active Serum is used at night, or on alternate days. Always introduce slowly and monitor your skin's response.

Active Serum works best for oily, combination, and acne-prone skin types. It's also excellent for mature skin concerned with fine lines and uneven tone. Those with dry or very sensitive skin should use with caution, start slowly, and always follow with a rich moisturizer. The menthol may be too intense for extremely reactive skin.

Most users notice smoother, clearer skin within the first few days to one week. Active breakouts often calm within 1-2 days of spot treatment. Visible improvements in texture and pore size typically appear within 2 weeks. For significant fading of hyperpigmentation and fine lines, expect to see results in 4-8 weeks of consistent use.

Apply Active Serum after cleansing and toning, but before heavier serums, moisturizer, and sunscreen. Use 3-4 drops on clean, dry skin. Wait for the tingling to subside before applying your next product. Can be used morning or evening, but always follow with SPF 30+ if used in the AM due to increased photosensitivity from acids.

No, Active Serum has a very low comedogenic rating of 1/5. The formula is oil-free, lightweight, and specifically designed to clear pores rather than clog them. The BHA (willow bark) actually helps unclog pores and prevent breakouts. It's an excellent choice for those concerned about congestion.

Active Serum has a 12-month shelf life after opening (PAO). The dark glass dropper bottle helps protect the active ingredients from light degradation. Store in a cool, dry place and keep tightly closed. Since only 3-4 drops are needed per application, one bottle typically lasts 6+ months with daily use.

— Skincarisma verdict
4.6 / 5 ★★★★★

Verdict: iS Clinical Active Serum is a cult-favorite for good reason. This multi-tasking powerhouse delivers on its promises with clinically-proven results for acne, aging, and brightening. The botanical-derived triple-acid formula is gentler than synthetic alternatives while remaining highly effective. Yes, the price is steep, but the concentrated formula means a little goes a long way – most bottles last 6+ months. Best suited for oily, combination, or acne-prone skin types seeking professional-grade results at home. A worthy investment for those who want one serum that truly does it all.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

Awesome, I Understand!

Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

Awesome, I Understand!

Notable Effects & Ingredients

brightening Brightening from 2 ingredient(s):
Glycerin Arbutin
wound Promotes Wound Healing from 2 ingredient(s):
Glycerin Arbutin
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

Awesome, I Understand!

Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
3
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

Awesome, I Understand!

Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
38% 15% 46%

Product ingredient list

Showing first 5 of 13 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
2 A
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
brightening Brightening
Promotes Wound Healing
Hydrating
1 A
Butylene Glycol
Solvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
Hydrating
0 Unknown
Alcohol Denat.
0 Unknown
Saccharum Officinarum Extract
Moisturising, Skin Conditioning
VIEW ALL INGREDIENTS