Active Serum
Active Serum
Product Description
Product overview
A powerful, fast-acting botanical serum that combines natural forms of glycolic, lactic, and salicylic acids to visibly reduce fine lines, even skin tone, and clear blemish-prone skin. This clinically-proven multi-tasking formula delivers results within days, leaving skin smooth, bright, and refreshed.
Triple-Acid Exfoliation
Botanical-derived glycolic, lactic, and salicylic acids work synergistically to resurface skin at multiple levels.
Texture & feel
SENSORYTriple-Acid Exfoliation
Botanical-derived glycolic, lactic, and salicylic acids work synergistically to resurface skin at multiple levels.
Brightening Complex
Arbutin and mushroom extract help fade dark spots and even out skin tone for a luminous complexion.
Pore-Clearing Action
Willow bark extract (natural BHA) penetrates deep into pores to clear congestion and prevent breakouts.
Fast-Acting Formula
Clinically proven to show visible results within days, not weeks. Most users notice improvement quickly.
Safety & compatibility
SAFEContains willow bark (salicylate) and arbutin. Consult your healthcare provider before use during pregnancy or nursing. Some dermatologists advise caution.
Oil-free, no fatty acids, no ferments. This formula does not feed malassezia yeast and is safe for fungal acne-prone skin.
Rated 1/5 for pore-clogging potential. Lightweight, oil-free formula is unlikely to cause breakouts or congestion.
Contains alcohol denat. and menthol which may cause tingling. Start with every other day use and always follow with SPF.
Ingredient breakdown
INGREDIENTSSugar Cane Extract 8%Proven
Natural source of glycolic acid, the smallest AHA molecule that penetrates deeply to exfoliate the stratum corneum and boost cell turnover.
- Function: Desquamation agent that encourages gentle exfoliation
- Benefit: Smooths texture, fades discoloration, stimulates collagen
Bilberry Extract 2%Proven
Natural source of lactic acid from Vaccinium Myrtillus fruit. Rich in antioxidants that gently exfoliate while promoting healthy blood flow.
- Function: AHA exfoliant with antioxidant properties
- Benefit: Softens fine lines, increases collagen production, calms skin
Willow Bark Extract 2%Proven
Natural source of salicylic acid (BHA) from Salix Alba bark. Oil-soluble to penetrate deep into pores and clear congestion.
- Function: BHA that exfoliates inside the pore lining
- Benefit: Unclogs pores, reduces inflammation, prevents breakouts
Arbutin —Proven
Plant-derived brightening agent that inhibits tyrosinase enzyme to reduce melanin production and fade hyperpigmentation.
- Function: Tyrosinase inhibitor for skin brightening
- Benefit: Fades dark spots, evens skin tone, reduces post-acne marks
Mushroom Extract —Promising
Polyporus Umbellatus extract rich in fatty acids that supports skin barrier function and promotes a radiant complexion.
- Function: Skin conditioning and barrier support
- Benefit: Improves moisture retention, boosts collagen, calms inflammation
13 ingredients
Water/Aqua/Eau, Glycerin, Butylene Glycol, Alcohol Denat., Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Vaccinium Myrtillus Fruit/Leaf Extract, Triethanolamine, Salix Alba (Willow) Bark Extract, Glyceryl Polyacrylate, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol
Where it fits in your routine
ROUTINEApply after cleansing/toning, before heavier treatments. Do not use with retinol or other AHA/BHA products on the same night.
How to use
HOW TO USECleanse Your Skin
Start with clean, dry skin. Use a gentle cleanser to remove makeup and impurities.
Apply 3-4 Drops
Dispense drops onto palm or fingertips. A little goes a long way with this concentrated formula.
Dab and Smooth
Gently press and smooth evenly over face and neck. Avoid immediate eye area.
Allow to Absorb
Expect a cool tingling sensation that dissipates within a few minutes. This indicates the serum is working.
Follow with Moisturizer
Layer with your favorite moisturizer. In AM, always finish with SPF 30+.
Who is it for?
WHOPerfect for you if:
- You struggle with acne, breakouts, or congested pores
- You want to fade dark spots and even skin tone
- You're looking to reduce fine lines and wrinkles
- You have oily or combination skin
- You want multi-tasking anti-aging benefits
- You prefer botanical-based actives over synthetic
Consider alternatives if:
- You're pregnant or breastfeeding (consult doctor first)
- You have extremely sensitive or reactive skin
- You're allergic to aspirin or salicylates
- You're already using strong retinoids daily
- You prefer fragrance-free products with no menthol
- You're on a tight budget (this is a premium product)
Skin type compatibility
SKIN TYPESOil-free, lightweight formula absorbs instantly. BHA helps control excess sebum and clear pores.
Balances oily T-zone while providing hydration. Works across different facial zones effectively.
Triple-acid formula targets breakouts at every level. Non-comedogenic and fungal acne safe.
Contains alcohol which may be drying. Always layer with rich moisturizer. Start every other day.
Menthol tingling may be intense. Patch test first. Mix with Hydra-Cool Serum to buffer if needed.
Excellent for fine lines, wrinkles, and age spots. Glycolic acid boosts collagen production effectively.
Results timeline
MONTH 2-3Immediate Clarity
Skin feels smoother and looks more refined. Active breakouts begin calming down. Initial brightness boost visible.
78% noticed improvementVisible Texture Improvement
Pores appear smaller and cleaner. Skin texture becomes noticeably smoother. Breakouts reduce in frequency.
85% saw clearer skinTone Evening
Dark spots and post-acne marks begin to fade. Overall skin tone appears more even and luminous.
72% reported brighter skinSignificant Transformation
Fine lines visibly reduced. Hyperpigmentation significantly faded. Skin looks healthier and more youthful overall.
68% saw anti-aging resultsRatings by platform
7K+ REVIEWSPros & cons
BALANCEDPraised
- Fast-acting results visible within days
- Multi-tasking: acne, aging, and brightening in one
- Lightweight, absorbs instantly
- A little goes a long way - bottle lasts 6+ months
- Clinically proven with independent studies
- Beloved by dermatologists and estheticians
- Oil-free and fungal acne safe
- Works for all ages and most skin types
Criticized
- High price point ($92+ for 1 oz)
- Intense tingling may be uncomfortable
- Contains alcohol denat. (potentially drying)
- Small bottle size for the cost
- Not pregnancy-safe without doctor approval
- May cause purging initially
- Menthol can irritate very sensitive skin
Budget-friendly alternatives (dupes)
DUPESContains 2% salicylic acid without AHAs. Excellent for pore-clearing but lacks glycolic/lactic acid for anti-aging benefits. No arbutin for brightening.
Much higher acid concentration but used only as weekly peel (10 min). Not daily-use like Active Serum. More intense, requires careful introduction.
Similar acid percentages with fruit-derived AHAs. Clean formula, no alcohol. Lacks willow bark specifically and arbutin brightening complex.
Lactic acid-focused toner with azelaic acid for brightening. Gentler formula, good for sensitive skin. Less potent overall but daily-use friendly.
Comparison with competitors
SIDE-BY-SIDEStorage & shelf life
12 MONTHS12 months after opening
Store in cool, dry place away from direct sunlight. Keep tightly closed after use.
Dark glass dropper bottle to protect active ingredients from light degradation
Yes, 30ml/1oz is under TSA liquid limit for carry-on luggage
Frequently asked questions
FAQActive Serum contains willow bark extract (a natural salicylate) and arbutin, which some healthcare providers recommend avoiding during pregnancy and breastfeeding. While the brand states it's "suitable for new moms," we recommend consulting your doctor or dermatologist before use during pregnancy or while nursing to ensure safety for your specific situation.
Yes! Active Serum is fungal acne safe. The formula is oil-free, contains no fatty acids, fermented ingredients, or esters that feed malassezia yeast. The lightweight, water-based formula makes it an excellent choice for those prone to fungal acne or pityrosporum folliculitis.
Do not use Active Serum on the same night as retinol or other AHA/BHA products to avoid over-exfoliation and irritation. You can alternate nights (Active Serum one night, retinol the next). Vitamin C can be used in the morning while Active Serum is used at night, or on alternate days. Always introduce slowly and monitor your skin's response.
Active Serum works best for oily, combination, and acne-prone skin types. It's also excellent for mature skin concerned with fine lines and uneven tone. Those with dry or very sensitive skin should use with caution, start slowly, and always follow with a rich moisturizer. The menthol may be too intense for extremely reactive skin.
Most users notice smoother, clearer skin within the first few days to one week. Active breakouts often calm within 1-2 days of spot treatment. Visible improvements in texture and pore size typically appear within 2 weeks. For significant fading of hyperpigmentation and fine lines, expect to see results in 4-8 weeks of consistent use.
Apply Active Serum after cleansing and toning, but before heavier serums, moisturizer, and sunscreen. Use 3-4 drops on clean, dry skin. Wait for the tingling to subside before applying your next product. Can be used morning or evening, but always follow with SPF 30+ if used in the AM due to increased photosensitivity from acids.
No, Active Serum has a very low comedogenic rating of 1/5. The formula is oil-free, lightweight, and specifically designed to clear pores rather than clog them. The BHA (willow bark) actually helps unclog pores and prevent breakouts. It's an excellent choice for those concerned about congestion.
Active Serum has a 12-month shelf life after opening (PAO). The dark glass dropper bottle helps protect the active ingredients from light degradation. Store in a cool, dry place and keep tightly closed. Since only 3-4 drops are needed per application, one bottle typically lasts 6+ months with daily use.
Verdict: iS Clinical Active Serum is a cult-favorite for good reason. This multi-tasking powerhouse delivers on its promises with clinically-proven results for acne, aging, and brightening. The botanical-derived triple-acid formula is gentler than synthetic alternatives while remaining highly effective. Yes, the price is steep, but the concentrated formula means a little goes a long way – most bottles last 6+ months. Best suited for oily, combination, or acne-prone skin types seeking professional-grade results at home. A worthy investment for those who want one serum that truly does it all.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 1 |
Butylene Glycol
Solvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
|
Hydrating
|
|
| 0 |
Alcohol Denat.
|
|
|
| 0 |
Saccharum Officinarum Extract
Moisturising, Skin Conditioning
|
|









