Advanced Retinol + Ferulic Intense Wrinkle Cream
Advanced Retinol + Ferulic Intense Wrinkle Cream
Product Description
Product overview
A rich, buttery retinol moisturizer powered by the proprietary Phyto-Retinol Blend™ — combining two forms of retinol with bakuchiol, ferulic acid, and rambutan — to visibly smooth wrinkles, firm skin, and deeply hydrate without irritation. Clinically proven to reduce fine lines in just 2 weeks.
Phyto-Retinol Blend™
Proprietary blend of trans-retinol + encapsulated retinol paired with bakuchiol, rambutan, and ferulic acid for enhanced anti-aging without irritation.
Texture & feel
SENSORYPhyto-Retinol Blend™
Proprietary blend of trans-retinol + encapsulated retinol paired with bakuchiol, rambutan, and ferulic acid for enhanced anti-aging without irritation.
24-Hour Hydration
Rich base of hyaluronic acid (3 molecular weights), ceramide NG, squalane, and shea butter delivers clinically proven all-day moisture.
Barrier Repair
Ceramides, squalane, and evening primrose oil strengthen the moisture barrier while retinol works underneath to stimulate collagen.
Antioxidant Shield
Ferulic acid, centella asiatica, arnica, and milk thistle protect against free radical damage and soothe retinol-treated skin.
Safety & compatibility
SAFEContains retinol (Vitamin A derivative). Retinoids are contraindicated during pregnancy and breastfeeding. Consult your doctor before use.
Contains fatty acid esters (caprylyl caprylate/caprate), shea butter, sweet almond oil, soybean oil, and other oils that may feed malassezia yeast.
Retinol increases photosensitivity. Always apply SPF 30+ during the day when using this product, even on cloudy days.
Clinically tested on Fitzpatrick Skin Types II-VI. Bakuchiol buffers retinol irritation. 100% of clinical study participants reported no irritation.
Certified cruelty-free by PETA. No animal-derived ingredients. Recyclable packaging.
Free from parabens, sulfates, phthalates, artificial fragrances, and drying alcohols.
Contains shea butter and sweet almond oil which are mildly comedogenic. Low risk for most skin types but patch test if very acne-prone.
Start by using every other night for the first 2 weeks, then gradually increase to nightly use as tolerated.
Ingredient breakdown
INGREDIENTSTrans-Retinol + Encapsulated RetinolProven
Two forms of Vitamin A work synergistically — trans-retinol provides immediate activity while encapsulated retinol delivers a sustained, slow release for reduced irritation and prolonged efficacy. Stimulates collagen production, accelerates cell turnover, and fades dark spots.
- Mechanism: Converts to retinoic acid in skin, binding to RAR/RXR receptors to upregulate collagen genes and downregulate MMPs (enzymes that break down collagen).
- Evidence: Thousands of peer-reviewed studies confirm retinol reduces wrinkle depth, improves skin elasticity, and evens pigmentation over 8-12 weeks of consistent use.
- Dual delivery: Trans-retinol acts fast; encapsulated retinol minimizes peak irritation by releasing gradually over hours.
BakuchiolProven
A plant-derived retinol alternative from the babchi plant that delivers retinol-like anti-aging benefits while reinforcing the moisture barrier. Works synergistically with retinol to boost efficacy and reduce irritation potential.
- Evidence: A 2019 study in the British Journal of Dermatology found bakuchiol and retinol produced comparable improvements in wrinkles and pigmentation over 12 weeks.
- Barrier support: Increases hydration levels and supports moisture barrier function, counteracting the drying effects of retinol.
- Tolerability: Does not cause the photosensitivity, peeling, or scaling commonly associated with retinoids.
Ferulic AcidProven
A potent plant-derived antioxidant found in rice bran and oats that stabilizes and enhances the performance of other actives while providing its own photoprotective and anti-aging benefits.
- Synergy: A landmark 2005 study showed ferulic acid doubles the photoprotection of Vitamin C + E formulations, and similarly stabilizes retinol against degradation.
- Anti-inflammatory: Counteracts the irritating effects of retinol and helps reduce UV-induced free radical damage.
- Penetration: Demonstrated ability to effectively penetrate the stratum corneum for delivery to deeper skin layers.
Rambutan (Nephelium Lappaceum) Leaf ExtractPromising
A tropical fruit extract rich in antioxidants that protects existing collagen from environmental degradation and supports skin elasticity and radiance.
- Collagen protection: Helps shield skin's natural collagen from breakdown caused by UV exposure and pollution.
- Elasticity: In brand studies, rambutan visibly improved skin elasticity and overall radiance.
Hyaluronic Acid Complex (3 Types)Proven
Three molecular weights of hyaluronic acid — sodium hyaluronate, hydrolyzed sodium hyaluronate, and sodium hyaluronate crosspolymer — provide multi-depth hydration from surface to deeper layers.
- Capacity: HA can hold up to 1000x its weight in water, creating a moisture reservoir in the skin.
- Multi-weight delivery: Large molecules hydrate the surface, medium molecules plump mid-layers, and small molecules penetrate deepest for long-lasting hydration.
- Crosspolymer: Creates a breathable moisture film for sustained hydration over 24 hours.
Ceramide NG + SqualaneProven
Skin-identical lipids that mirror the natural composition of the skin barrier. Ceramide NG fills gaps between skin cells while squalane provides emollient moisture — together they repair and reinforce a compromised barrier.
- Barrier repair: Ceramides make up ~50% of the skin barrier's lipid matrix. Topical application directly fills structural gaps.
- Squalane: A stable form of squalene (naturally found in human sebum) that penetrates quickly without clogging pores.
- Retinol support: Essential for preventing the moisture loss and barrier disruption that retinol can cause.
47 ingredients
Water/Aqua/Eau, Methyl Glucose Sesquistearate, Glycerin, Diisostearyl Malate, Caprylyl Caprylate/Caprate, Cetearyl Alcohol, Butyrospermum Parkii (Shea) Butter, Dimethicone, Propylene Glycol, Caprylic/Capric Triglyceride, Cetyl Alcohol, Bakuchiol, Retinol, Ferulic Acid, Nephelium Lappaceum Leaf Extract, Sodium Hyaluronate, Squalane, Oenothera Biennis (Evening Primrose) Oil, Ceramide NG, Emblica Officinalis Fruit Extract, Silybum Marianum Extract, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Jojoba Esters, Soy Isoflavones, Phospholipids, Saccharide Isomerate, Hippophae Rhamnoides Fruit Oil, Centella Asiatica Extract, Ursolic Acid, Adenosine, Camellia Japonica Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Arnica Montana Flower Extract, Salix Alba (Willow) Bark Extract, Pyrus Malus (Apple) Fruit Extract, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Glycine Soja (Soybean) Oil, Tocopherol, Sodium Acetylated Hyaluronate, Hydroxyacetophenone, Caprylyl Glycol, 1,2-Hexanediol, Xanthan Gum, Carbomer, Tromethamine, Ethylhexylglycerin, BHT
Where it fits in your routine
ROUTINEUse as your moisturizer step AM & PM. For best results, apply after your Dr. Dennis Gross peel pad and serum. Always follow with SPF in the morning.
How to use
HOW TO USECleanse & Prep
Start with a clean, dry face. If using a toner or peel pad, apply those first and let them absorb fully.
Apply Serum (Optional)
Layer your treatment serum underneath if you use one. Wait 30–60 seconds for absorption before the next step.
Apply Wrinkle Cream
Take a pea-sized amount and massage into face and neck using upward, circular motions. Extend to décolleté area. A little goes a long way.
Sunscreen (AM Only)
In the morning, always follow with a broad-spectrum SPF 30 or higher. Retinol increases sun sensitivity significantly.
Start Slow
If new to retinol, begin every other night for the first 2 weeks, then gradually increase to nightly use as your skin builds tolerance.
Who is it for?
WHOPerfect for you if:
- You want to address fine lines, wrinkles, and loss of firmness
- You have dry or dehydrated skin and need retinol that also moisturizes
- You want a retinol product gentle enough for sensitive skin
- You prefer a single product that combines anti-aging and hydration
- You appreciate clinically tested, dermatologist-formulated products
- You want to improve uneven texture and dull skin tone
Consider alternatives if:
- You are pregnant or breastfeeding (contains retinol)
- You have fungal acne/malassezia — formula contains triggering oils and esters
- You prefer a lightweight gel texture — this is a rich, buttery cream
- You are on a tight budget — at $82 for 2 oz, this is a premium product
- You need a high-concentration retinol (this uses a gentler, undisclosed %)
- You have very oily skin and prefer oil-free formulas
Skin type compatibility
SKIN TYPESSpecifically designed for dry skin. Rich, buttery texture with ceramides, squalane, and shea butter delivers 24-hour hydration without flaking.
Ideal for normal skin seeking anti-aging benefits. Balanced hydration without heaviness; absorbs to a silky matte finish.
Works well overall. May feel slightly rich on the T-zone during summer — use a thinner layer on oily areas if needed.
Rich buttery texture may feel heavy for very oily skin. Consider the lighter Overnight Wrinkle Treatment serum from the same line instead.
Clinically tested with zero irritation reported. Bakuchiol buffers retinol effects. Still recommended to start slowly and patch test first.
Retinol helps normalize keratinization and reduce sebum, but the rich formula with oils and shea butter may not suit breakout-prone skin. Not fungal acne safe.
Results timeline
WEEK 8–12Instant Hydration & Smoothness
Skin feels softer, smoother, and intensely moisturized. Dry fine lines appear visibly reduced due to the plumping effect of hyaluronic acid and ceramides.
94% saw smoother skin immediatelyVisible Fine Line Reduction
Clinically significant reduction in dry fine lines. Skin texture begins to refine and overall complexion appears brighter and more even.
94% showed reduction in dry fine linesImproved Tone & Radiance
Retinol-driven cell turnover reveals fresher skin underneath. Uneven skin tone begins to even out and overall appearance improves notably.
97% saw improvement in overall appearanceFirming & Elasticity
Collagen stimulation becomes visible with firmer, more resilient skin. Elasticity improves and deeper wrinkles begin to soften.
85% saw firmer skin and improved elasticityComprehensive Anti-Aging
Full results achieved — pronounced wrinkle reduction, visibly firmer and lifted skin, restored moisture barrier, and dramatically smoother texture.
100% saw smoother, less oily skin with no irritationRatings by platform
1K+ REVIEWSPros & cons
BALANCEDPraised
- Clinically proven results — 94% saw fine line reduction immediately
- Dual retinol delivery system minimizes irritation
- Rich, luxurious texture that leaves skin soft and hydrated
- Bakuchiol boosts efficacy while buffering potential sensitivity
- Multi-ingredient formula with ceramides, squalane, and 3 types of HA
- Suitable for AM and PM use — doubles as moisturizer
- Dermatologist-formulated by board-certified Dr. Dennis Gross
- Vegan, cruelty-free, and free from parabens/sulfates
Criticized
- Premium price at $82 for 2 oz ($41/oz)
- Jar packaging exposes retinol to air and light, reducing potency over time
- Rich, buttery texture too heavy for oily skin types
- Retinol concentration not disclosed on label
- Not safe for pregnancy, breastfeeding, or fungal acne
- Some users reported initial irritation or rash (patch test recommended)
- Results can take several weeks to become noticeable for deeper wrinkles
Budget-friendly alternatives (dupes)
DUPESContains encapsulated retinol with ceramides, hyaluronic acid, and niacinamide in a similar barrier-repair approach. Lighter texture, fragrance-free, but lacks bakuchiol and ferulic acid. Great entry-level option.
Pure retinol in a squalane base at a known concentration (0.5%). Much simpler formula — no bakuchiol, ferulic acid, ceramides, or HA. Oily texture, no cream base. Effective but more likely to cause irritation.
Features accelerated retinol SA with hyaluronic acid and glucose complex in a rich cream base. Very similar anti-wrinkle approach at a fraction of the price. No bakuchiol or ferulic acid; contains fragrance.
Combines bakuchiol with encapsulated retinol — similar dual approach. Lighter serum texture, not a cream. Clean beauty formulation. Lacks the ceramides, HA complex, and ferulic acid of the DDG cream.
Comparison with competitors
SIDE-BY-SIDERoC Retinol Correxion Max Wrinkle Resurfacing
Storage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight. Keep jar tightly sealed to protect retinol from air exposure and oxidation.
Glass jar with screw-top lid. Recyclable packaging. Consider using a spatula to avoid introducing bacteria from fingers.
Yes — 2 oz is under the 3.4 oz TSA liquid limit for carry-on luggage. Ensure lid is tightened securely.
Frequently asked questions
FAQNo. This product contains retinol (Vitamin A derivative), which is contraindicated during pregnancy and breastfeeding due to potential risks of birth defects. While bakuchiol alone is considered safe during pregnancy, this formula includes retinol and should be avoided. Consult your OB-GYN or dermatologist for pregnancy-safe alternatives.
No. This formula contains several ingredients that can feed malassezia yeast, including caprylyl caprylate/caprate, shea butter, sweet almond oil, evening primrose oil, sea buckthorn oil, soybean oil, camellia seed oil, and sunflower seed oil. If you have fungal acne, look for an oil-free retinol treatment instead.
This cream already contains retinol, so avoid layering additional retinol products on top to prevent over-exfoliation. Vitamin C can be used in your AM routine while using this cream at night, but avoid applying them simultaneously if you experience sensitivity. AHAs and BHAs (like glycolic acid or salicylic acid) can be alternated on different nights. Dr. Dennis Gross recommends using their Alpha Beta peel pads before this cream for enhanced results — start slowly to assess tolerance.
This cream is best suited for dry, normal, and combination skin types. The rich, buttery texture with shea butter, ceramides, and squalane makes it ideal for those who need both anti-aging treatment and intense hydration. If you have oily skin, consider the lighter Advanced Retinol + Ferulic Overnight Wrinkle Treatment serum from the same line. It was clinically tested on Fitzpatrick Skin Types II-VI and is marked safe for sensitive skin.
In clinical studies, 94% of participants saw smoother skin and a reduction in dry fine lines immediately upon application due to the hydrating ingredients. Visible texture and tone improvements typically appear within 2 weeks of daily use. For deeper wrinkle reduction and firming benefits, expect 4–12 weeks of consistent use as retinol stimulates collagen production over time.
Apply as your moisturizer step — after cleansing, toning, and serums, but before sunscreen (AM) or as your final step (PM). For optimal results, the brand recommends applying after their Alpha Beta Daily Peel and a serum. It is designed for both morning and evening use.
We rate this a 2 out of 5 on the comedogenic scale. It contains shea butter (comedogenic rating 0–2), sweet almond oil (rating 2), and several other oils. While these are generally considered low risk, individuals who are very acne-prone should patch test first. The retinol component actually helps normalize skin cell turnover and reduce sebum production, which can be beneficial for pores.
The recommended Period After Opening (PAO) is 12 months. However, since retinol degrades when exposed to air and light, and this product comes in a jar (not an airless pump), we recommend using it within 6–8 months for optimal potency. Always reseal the jar tightly after each use, use a clean spatula, and store away from direct sunlight.
Verdict: Dr. Dennis Gross Advanced Retinol + Ferulic Intense Wrinkle Cream is a premium, clinically-backed anti-aging moisturizer that excels at delivering retinol results without the typical irritation. The Phyto-Retinol Blend™ of dual retinol + bakuchiol is thoughtfully formulated, and the supporting cast of ferulic acid, triple hyaluronic acid, ceramides, and squalane makes this a powerhouse for dry and aging skin. The main drawbacks are the premium price point ($82 for 2 oz), jar packaging that isn't ideal for retinol stability, and a rich texture that may be too heavy for oily skin. If you want a retinol moisturizer that won't compromise on hydration and you're willing to invest, this is an excellent choice — especially for those with dry or normal skin concerned about wrinkles, firmness, and dull texture.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 1 |
Methyl Glucose Sesquistearate
Skin Conditioning, Emollient, Emulsifying
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 1 |
Diisostearyl Malate
Skin Conditioning, Emollient, Surfactant
|
|
|
| 0 |
Caprylyl Caprylate/Caprate
Emollient, Skin Conditioning
|
Hydrating
|








