Anthelios UVMune 400 Anti Dark-Spot Fluid SPF 50+
Anthelios UVMune 400 Anti Dark-Spot Fluid SPF 50+
Product Description
An advanced SPF 50+ fluid sunscreen combining revolutionary Mexoryl 400 UV filter technology with Melasyl to protect against ultra-long UVA rays while actively targeting and preventing dark spots and hyperpigmentation. Lightweight, invisible finish with no white cast.
β¨ Texture & Feel
Mexoryl 400 Technology
L'OrΓ©al's biggest sun filtering innovation in 30 years. Protects against ultra-long UVA rays (380-400nm) that penetrate deepest into skin.
Melasyl Active
Patented molecule that intercepts excess melanin before it marks the skin, helping prevent and reduce dark spots and hyperpigmentation.
Netlock Technology
Creates a protective homogeneous film on skin that resists water, sweat, and sand while maintaining an invisible, lightweight feel.
8 UV Filters System
Comprehensive broad-spectrum protection combining multiple photostable filters including Tinosorb S, Avobenzone, and proprietary Mexoryl filters.
π‘οΈ Safety & Compatibility
Contains chemical UV filters. While no adverse effects reported, mineral sunscreens are typically preferred during pregnancy. Consult your healthcare provider.
Contains Polysorbate 60 which may be a trigger for some. The standard UVMune 400 Invisible Fluid is fungal acne safe; patch test recommended.
Dermatologically tested on sensitive and reactive skin. Fragrance-free, hypoallergenic formula. Contains La Roche-Posay Thermal Spring Water.
Ophthalmologist tested. Anti-eye stinging formula can be applied around the eyes. Tested on contact lens wearers.
Does not contain oxybenzone or octinoxate. Uses newer generation filters with minimal environmental impact.
Contains Alcohol Denat. for quick-dry texture. May feel slightly drying on very dry skin types; layer over moisturizer if needed.
π¬ Ingredient Breakdown
βοΈ Mexoryl 400 (MCE) Revolutionary
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate - L'OrΓ©al's exclusive UV filter developed over 10 years with 25 patents. The most effective filter against ultra-long UVA rays (380-400nm).
- Innovation: First filter specifically designed to protect against the most penetrating UV rays
- Protection: Covers the 380-400nm wavelength range that other filters miss
- Stability: Highly photostable, doesn't degrade under sun exposure
β¨ Melasyl (2-MNG) Patented
2-Mercaptonicotinoyl Glycine - Revolutionary anti-pigmentation molecule based on 18 years of research. Intercepts excess melanin before it deposits in the skin.
- Mechanism: Inhibits melanin synthesis and UV-induced immediate pigmentation
- Clinical Study: 60% reduction in spot visibility by day 84
- Safety: Proven efficacy across all skin tones (Fitzpatrick I-VI)
π‘οΈ Tinosorb S (Bemotrizinol) 2.2-2.7% Gold Standard
Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine - One of the best broad-spectrum sunscreen agents available. Covers both UVA and UVB (280-400nm).
- Spectrum: Peak protection at 310nm and 345nm
- Stability: Highly photostable, helps stabilize Avobenzone
- Safety: No estrogenic activity, excellent safety profile
π Avobenzone ~2% UVA Gold Standard
Butyl Methoxydibenzoylmethane - The global gold standard for UVA protection. Most widely used UVA filter worldwide.
- UVA Protection: Peak absorption in UVA range (310-400nm)
- Stabilized: Combined with Tinosorb S and Mexoryl filters for enhanced stability
π§ Glycerin ~1% Proven
Classic humectant that attracts moisture to the skin. Prevents the formula from being too drying despite alcohol content.
- Function: Draws moisture from the environment to skin surface
- Comedogenic Rating: 0 - Will not clog pores
π Tocopherol (Vitamin E) Antioxidant
Natural antioxidant that provides additional UVB protection and helps prevent oxidative damage from sun exposure.
- Protection: Neutralizes free radicals generated by UV exposure
- Synergy: Enhances overall sun protection when combined with UV filters
33 ingredients
Aqua/Water/Eau, Alcohol Denat., Silica, Diisopropyl Adipate, Diisopropyl Sebacate, Ethylhexyl Triazone, Butyl Methoxydibenzoylmethane, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Dicaprylyl Carbonate, Glycerin, Propanediol, C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer, Diethylamino Hydroxybenzoyl Hexyl Benzoate, C12-15 Alkyl Benzoate, Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate, Perlite, Drometrizole Trisiloxane, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Citric Acid, Disodium Phosphate, Hydroxyacetophenone, Hydroxyethylcellulose, 2-Mercaptonicotinoyl Glycine, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Pentylene Glycol, Polysorbate 60, Sodium Phosphate, Sodium Thiosulfate, Terephthalylidene Dicamphor Sulfonic Acid, Tocopherol, Triethanolamine, Trisodium Ethylenediamine Disuccinate
π Where It Fits in Your Routine
Apply as the final step of your morning skincare routine, before makeup. Wait 1-2 minutes before applying makeup for best results.
π How to Use
Shake Well
Always shake the bottle before use to ensure the formula is evenly mixed and UV filters are properly distributed.
Apply Generously
Dispense approximately 1/4 teaspoon (2mg/cmΒ²) for face and neck. Apply to dry skin 15 minutes before sun exposure.
Spread Evenly
Gently spread and pat into skin until fully absorbed. Can be applied around the eye area without stinging.
Reapply Frequently
Reapply every 2 hours, and immediately after swimming, sweating, or towel drying to maintain protection.
π€ Who Is It For?
β Perfect for you if:
- You have dark spots, melasma, or hyperpigmentation concerns
- You want the highest level of UVA protection available
- You prefer lightweight, non-greasy sunscreens
- You need a sunscreen that works under makeup
- You have sensitive or reactive skin
- You want protection against photoaging and sun damage
- You spend extended time outdoors
- You have oily or combination skin
β Consider alternatives if:
- You are pregnant and prefer mineral-only sunscreens
- You have very dry skin (may need extra moisturizer underneath)
- You prefer thicker, more moisturizing textures
- You are extremely sensitive to alcohol in skincare
- You have severe fungal acne (Polysorbate 60 may trigger)
- You need a budget-friendly everyday option
π― Skin Type Compatibility
Oil-free, ultra-light fluid absorbs quickly without adding shine. Alcohol helps control excess sebum. Natural-matte finish.
Lightweight texture may not provide enough hydration. Best layered over a rich moisturizer. Alcohol content may feel slightly drying.
Perfect balance - controls oil in T-zone while not over-drying cheeks. Invisible finish works well across different face zones.
Fragrance-free, dermatologically tested on sensitive skin. Contains soothing Thermal Spring Water. Patch test if very reactive.
Non-comedogenic (rating 1/5), oil-free formula. Won't clog pores. Contains Polysorbate 60 which may affect fungal acne sufferers.
Specifically designed for this concern. Melasyl actively targets dark spots while superior UVA protection prevents new ones forming.
π Results Timeline
Instant Protection & Radiance
Full SPF 50+ and UVA protection active immediately. Skin appears more radiant and even-toned. No white cast or greasy residue.
100% immediate protectionPrevention of New Dark Spots
With consistent daily use, Melasyl begins intercepting excess melanin. New sun-induced dark spots are prevented from forming.
85% noticed prevention of new spotsVisible Spot Reduction
Existing dark spots begin to fade. Clinical studies show significant decrease in contrast between spots and surrounding skin.
70% reported fading of existing spotsMaximum Dark Spot Correction
Clinical studies demonstrate 60% reduction in spot visibility. Skin tone appears more even and radiant overall.
60% spot visibility reduction (clinical)β Ratings by Platform
βοΈ Pros & Cons
β Praised
- Revolutionary Mexoryl 400 offers unprecedented UVA protection
- Melasyl actively treats and prevents dark spots
- Truly invisible - no white cast on any skin tone
- Lightweight, non-greasy texture
- Works beautifully under makeup
- Water, sweat, and sand resistant (80 min)
- Anti-eye stinging formula
- Fragrance-free and dermatologically tested
- PPD 46 - exceptional UVA protection
- Recommended by 60,000+ dermatologists worldwide
β Criticized
- Higher price point than basic sunscreens (~Β£21-25)
- Very liquid texture can be messy to apply
- 50ml size runs out quickly with proper application
- Contains alcohol which may dry some skin types
- Not available in US (Mexoryl 400 not FDA approved)
- Contains Polysorbate 60 (fungal acne trigger for some)
- May not be moisturizing enough for very dry skin
- Slight chemical smell from Mexoryl 400 filter
π° Budget-Friendly Alternatives (Dupes)
Same L'OrΓ©al parent company with similar UV filters. Lacks Mexoryl 400 and Melasyl but offers good UVA protection. More affordable for daily use.
Same Mexoryl 400 technology but without Melasyl anti-dark spot active. Fungal acne safe version. Choose this if you don't need spot treatment.
Excellent oil control and matte finish. Good European filters but lacks Mexoryl 400 and anti-dark spot technology. Better for oily skin prioritizing mattification.
Targets dark spots and aging with different actives (Vitamin E, bakuchiol). Good protection but different technology approach. Richer texture.
π Comparison with Competitors
La Roche-Posay Anthelios UVMune 400 Anti Dark-Spot
Β£21.00Eucerin Oil Control Face Sun Gel-Cream SPF 50+
Β£15.00Bioderma Photoderm Spot-Age SPF 50+
Β£19.00ISDIN FotoUltra 100 Active Unify SPF 50+
Β£35.00π¦ Storage & Shelf Life
12 months after opening. Check the PAO symbol on packaging.
Store in a cool, dry place away from direct sunlight. Do not expose to extreme temperatures. Keep cap tightly closed.
Plastic squeeze bottle with flip-top cap. Shake before each use to mix formula properly.
Yes - 50ml is under the 100ml liquid limit for carry-on luggage. Compact, leak-proof design.
β Frequently Asked Questions
This sunscreen contains chemical UV filters (organic filters) rather than mineral-only protection. While no adverse effects have been specifically linked to these filters during pregnancy, many healthcare providers recommend mineral sunscreens (zinc oxide/titanium dioxide) during pregnancy and breastfeeding as the most conservative option. The chemical filters in this product have good safety profiles and minimal systemic absorption, but if you prefer to err on the side of caution, consider La Roche-Posay's mineral sunscreen options. Always consult your healthcare provider for personalized advice.
This specific Anti Dark-Spot version contains Polysorbate 60, which can be a trigger for some people with fungal acne (malassezia folliculitis). If you have fungal acne concerns, the original La Roche-Posay Anthelios UVMune 400 Invisible Fluid (without the anti-dark spot formula) is considered fungal acne safe. Patch testing is recommended if you're prone to fungal acne but want to try this product for its dark spot benefits.
Yes! This sunscreen is excellent to pair with active ingredients. In fact, using SPF is essential when using retinol, vitamin C, or acids as these can increase sun sensitivity. Apply your actives (vitamin C in morning, retinol at night, acids as directed) and always finish your morning routine with this sunscreen. The Melasyl technology will complement your anti-pigmentation actives beautifully. Wait 1-2 minutes between products for proper absorption.
This sunscreen is best suited for oily, combination, and normal skin types. Its ultra-light fluid texture and oil-free formula work particularly well for those with oily or combination skin. It's also excellent for anyone with hyperpigmentation concerns regardless of skin type. Dry skin types can use it but may need to apply over a hydrating moisturizer, as the alcohol content and lightweight texture may not provide enough moisture on their own.
Sun protection is immediate upon application. For dark spot reduction, clinical studies show: prevention of new dark spots within 2-4 weeks of consistent use, visible fading of existing spots at 8 weeks, and maximum results (60% reduction in spot visibility) at 12 weeks (84 days). Results depend on consistent daily use, proper application amount, and regular reapplication. Pair with other brightening products for enhanced results.
Apply as the LAST step of your morning skincare routine, before makeup. The correct order is: Cleanser β Toner β Serum/Essence β Moisturizer β Sunscreen. Wait 1-2 minutes after applying moisturizer before applying sunscreen. If wearing makeup, wait another 1-2 minutes after sunscreen before applying primer or foundation. Never mix sunscreen with other products as this can compromise protection.
This sunscreen has a comedogenic rating of 1/5, meaning it has a very low likelihood of clogging pores. It is oil-free and non-comedogenic. The formula was tested on acne-prone and sensitive skin. However, proper cleansing at night is essential - use an oil-based cleanser or cleansing balm to thoroughly remove sunscreen, followed by a water-based cleanser (double cleansing method) to ensure no residue remains.
The product has a PAO (Period After Opening) of 12 months. Once opened, use within 12 months for optimal efficacy. Store in a cool, dry place away from direct sunlight. Note: With proper daily application (about 1/4 teaspoon for face and neck), a 50ml bottle typically lasts 4-6 weeks for face-only use. Consider the expiration date if purchasing multiple bottles in advance.
Verdict: La Roche-Posay Anthelios UVMune 400 Anti Dark-Spot Fluid SPF 50+ represents the cutting edge of sun protection technology. The revolutionary Mexoryl 400 filter provides unprecedented protection against ultra-long UVA rays (380-400nm) - the most damaging and deeply penetrating rays that other sunscreens miss. Combined with Melasyl, a patented molecule that actively prevents and treats hyperpigmentation, this is a powerhouse for anyone serious about preventing photoaging and dark spots. The lightweight, invisible texture makes it a pleasure to wear daily, and it performs beautifully under makeup. While the higher price point and potential fungal acne trigger ingredient (Polysorbate 60) are considerations, for those battling dark spots or seeking the ultimate in UVA protection, this is currently one of the best options available outside the US. A must-have for hyperpigmentation-prone skin.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging Β«promisesΒ» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 0 |
Alcohol Denat.
|
|
|
| 0 |
Silica
Absorbent, Abrasive
|
|
|
| 1 |
Diisopropyl Adipate
Solvent, Skin Conditioning, Masking, Emollient, Fragrance, Plasticizer
|
|
|
| 1 |
Diisopropyl Sebacate
Solvent, Skin Conditioning, Emollient, Plasticizer
|
|

