Cicalfate+ Purifying Cleansing Gel
Cicalfate+ Purifying Cleansing Gel
Product Description
Product overview
A gentle, non-drying purifying cleansing gel formulated with Avène's exclusive postbiotic [C+-Restore] and a Copper-Zinc antibacterial complex. Designed for the hygiene of reactive, irritated skin on face, body, hands, and external intimate areas — safe for the whole family from birth.
Postbiotic [C+-Restore]
Exclusive repairing active derived from Aquaphilus dolomiae, a unique bacterium found in Avène Thermal Spring Water. Promotes epidermal repair and supports the skin microbiome.
Texture & feel
SENSORYPostbiotic [C+-Restore]
Exclusive repairing active derived from Aquaphilus dolomiae, a unique bacterium found in Avène Thermal Spring Water. Promotes epidermal repair and supports the skin microbiome.
Copper-Zinc Antibacterial Complex
Purifies and limits the proliferation of bacteria on the skin surface, providing a clean environment for optimal skin recovery.
Avène Thermal Spring Water
Clinically proven across 150+ studies to soothe, soften, and calm reactive skin. Rich in mineral silicates with a balanced mineral composition.
Whole-Family Safe
Suitable from birth for face, body, hands, scalp, and external intimate areas. Tested under dermatological, pediatric, gynecological, and ophthalmological control.
Safety & compatibility
SAFEContains no retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe during pregnancy and breastfeeding. Safe from birth.
Contains Aquaphilus Dolomiae Ferment Filtrate, a ferment-derived ingredient that could theoretically feed Malassezia yeast. However, as a rinse-off cleanser with minimal skin contact time, the risk is considered low.
Water-based formula with gentle, non-comedogenic surfactants. No oils, silicones, or heavy emollients. Very unlikely to clog pores.
Uses Disodium Coco-Glucoside Citrate, Decyl Glucoside, and Sodium Cocoamphoacetate — all mild, plant-derived surfactants that cleanse without stripping the skin barrier. SLS/SLES-free.
Fragrance-free, paraben-free, soap-free, alcohol-free, silicone-free. Formulated to minimize the risk of allergic reactions. Tested on hypersensitive skin.
Recommended by dermatologists for use after superficial dermatological procedures, tattoo aftercare (after 24 hours), and for daily hygiene of compromised skin.
Ingredient breakdown
INGREDIENTSAquaphilus Dolomiae Ferment Filtrate (C+-Restore)Patented
Avène's exclusive postbiotic active ingredient derived from a unique bacterium (Aquaphilus dolomiae) discovered in Avène Thermal Spring Water. This is the cornerstone of the Cicalfate+ line and helps promote epidermal repair.
- Mechanism: Works on the skin microbiome to accelerate the rate of epidermal repair and support the skin's natural barrier restoration.
- Clinical evidence: Avène clinical studies show epidermal repair promotion from 48 hours of use in controlled settings.
- Origin: Postbiotic obtained from fermentation of Aquaphilus dolomiae bacterium — unique to Avène's thermal water source in Haut-Languedoc, France.
Copper Sulfate + Zinc SulfateProven
A dual-mineral antibacterial complex that purifies the skin by limiting bacterial proliferation, creating a cleaner environment conducive to skin recovery.
- Copper Sulfate: Known antimicrobial and anti-fungal properties. Helps limit skin surface contaminants.
- Zinc Sulfate: Astringent and anti-inflammatory mineral that helps control oil, supports healing, and provides mild antiseptic action.
- In-vitro study: Avène confirmed a purifying effect on representative skin contaminants within 5 minutes of application.
Avène Thermal Spring Water Key SolventProven
Naturally sourced from the spring in the Haut-Languedoc Natural Park, this thermal water has been clinically studied in over 150 publications for its skin-soothing properties.
- Composition: Rich in silicates and contains a balanced ratio of calcium, magnesium, and trace elements with a neutral pH.
- Clinical data: 150+ studies support its ability to soothe, soften, and calm reactive and sensitive skin.
- Tolerance study: 89 subjects, 1 application/day for 21 days confirmed soothing and calming effects under dermatological control.
Glycerin ~3-8%Proven
A classic, skin-identical humectant that draws moisture to the skin. Effective from as low as 3% concentration, it helps ensure this cleanser does not strip or dry out the skin.
- Function: Humectant and skin-identical moisturizer. Maintains skin lipids in a healthy liquid crystal state.
- Irritancy: 0 / Comedogenicity: 0 — one of the best-tolerated moisturizing ingredients available.
Gentle Surfactant TrioMild
The cleansing action comes from three plant-derived, biodegradable surfactants chosen for maximum gentleness on compromised skin.
- Disodium Coco-Glucoside Citrate: Nearly natural (Ecocert-approved), derived from coconut. Extremely mild and non-irritating.
- Decyl Glucoside: A non-ionic surfactant known for excellent skin tolerance, commonly used in baby products.
- Sodium Cocoamphoacetate: An amphoteric surfactant that gently cleanses without disrupting the skin barrier.
15 ingredients
Avène Thermal Spring Water (Avène Aqua), Water (Aqua), Glycerin, Disodium Coco-Glucoside Citrate, Decyl Glucoside, Sodium Cocoamphoacetate, Pentylene Glycol, Aquaphilus Dolomiae Ferment Filtrate, Arginine, Citric Acid, Copper Sulfate, Sodium Chloride, Trisodium Ethylenediamine Disuccinate, Tromethamine, Xanthan Gum, Zinc Sulfate
Where it fits in your routine
ROUTINEUse as your first step (cleanser) morning and/or evening. If double cleansing, use as your second cleanser after an oil-based makeup remover. Pair with Cicalfate+ Cream or Emulsion for a complete repair routine.
How to use
HOW TO USEWet the Skin
Dampen the affected area with lukewarm water. Can be used on face, body, hands, scalp, or external intimate areas.
Lather the Gel
Dispense a small amount into the palm of your hand. Mix with water and gently lather. The blue-tinted gel transforms into a soft foam.
Apply Gently
Apply the lather to the skin with gentle, circular motions. Do not scrub or rub vigorously — let the surfactants do the work.
Rinse & Pat Dry
Rinse thoroughly with plenty of lukewarm water. Gently pat skin dry with a clean towel — do not rub. Use 1–2 times daily.
Who is it for?
WHOPerfect for you if:
- You have reactive, irritated, or compromised skin
- You need a gentle cleanser after dermatological procedures (peels, laser)
- You are caring for a new tattoo (after 24 hours)
- You need a body wash for eczema-prone or atopic skin
- You want a single cleanser safe for the whole family, including newborns
- You need a gentle intimate wash for irritated areas
- Your current cleanser leaves your skin tight, dry, or stripped
- You are pregnant or breastfeeding and want a safe daily cleanser
Consider alternatives if:
- You need a deep-cleansing or exfoliating cleanser for oily/acne-prone skin
- You want a cleanser that removes heavy makeup or sunscreen (use an oil cleanser first)
- You prefer a heavily foaming wash with a "squeaky clean" feel
- You are strictly avoiding all ferment-derived ingredients due to fungal acne
- You want active ingredients like salicylic acid or glycolic acid in your cleanser
Skin type compatibility
SKIN TYPESThis product was specifically designed for reactive and hypersensitive skin. Fragrance-free, minimal ingredients, and dermatologically tested. An ideal choice.
Non-drying formula with glycerin ensures skin is not stripped of moisture. Leaves skin comfortable and soft after cleansing. Follow with a rich moisturizer.
Gentle cleansing without over-stripping sebum. May not feel deep-cleaning enough for very oily skin, but the zinc complex helps with purification.
Works well across different face zones. Cleanses without aggravating dry patches or over-stimulating oily areas. A balanced option.
Non-comedogenic and antibacterial. Great for post-acne skin recovery but does not contain acne-fighting actives like BHA. Best as a gentle supportive cleanser.
Results timeline
3–4 WEEKSSoothing & Comfort
Skin feels immediately soothed and comfortable after rinsing. No tightness or dryness. The Avène Thermal Spring Water delivers an instant calming sensation on reactive skin.
96% felt skin was soothed (clinical study)Purifying Effect
The Copper-Zinc complex begins its antibacterial action within 5 minutes of application, helping to reduce skin surface contaminants in a single wash.
Purifying effect confirmed in vitroReduced Irritation & Redness
With consistent twice-daily use, users typically notice a visible reduction in redness and irritation. Skin starts to feel more resilient and less reactive to external triggers.
94% found skin was durably comfortableSkin Barrier Improvement
The postbiotic [C+-Restore] supports epidermal repair over time. After 3–4 weeks of regular use as part of the Cicalfate+ routine, skin appears healthier, calmer, and more balanced.
76% noticed reduced itching sensationsRatings by platform
450+ REVIEWSPros & cons
BALANCEDPraised
- Extremely gentle — does not strip or dry out the skin
- Safe for the whole family including newborns
- Effective for post-procedure and tattoo aftercare
- Unique postbiotic ingredient supports skin repair
- Pleasant blue-tinted texture that foams nicely
- Fragrance-free and minimal ingredient list (only 15)
- Multi-use: face, body, hands, scalp, intimate areas
- 98% natural origin ingredients in recycled packaging
Criticized
- 200ml bottle can run out quickly with full-body use
- Not available at major US retailers like Sephora or Ulta
- Higher price than typical drugstore body washes
- Not deep-cleansing enough for heavy makeup removal
- Contains a ferment filtrate (potential concern for fungal acne)
- No active acne-fighting or exfoliating ingredients
Budget-friendly alternatives (dupes)
DUPESThe closest competitor — also a soothing cleansing gel with copper-zinc-manganese antibacterial agents and 5% panthenol. Contains SLS (Sodium Laureth Sulfate) so slightly less gentle. Does not have a postbiotic ingredient.
A gentle foaming gel for atopic and sensitive skin. Contains glycerin and niacinamide for barrier repair. Larger 200ml bottle often at a lower price. Lacks the copper-zinc complex and postbiotic repair technology.
A widely available, affordable gentle cleanser with ceramides, hyaluronic acid, and niacinamide. Excellent for daily use but lacks the antibacterial purifying action and postbiotic repair benefits of Cicalfate+.
Comparison with competitors
SIDE-BY-SIDEStorage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place at room temperature. Keep away from direct sunlight and extreme heat.
100% recycled and recyclable plastic bottle with unscrewable cap. Blue-tinted gel visible through the bottle.
No — 200ml exceeds the 100ml/3.4oz carry-on liquid limit. Transfer to a travel-sized bottle for flights.
Frequently asked questions
FAQYes. This cleanser contains no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients flagged as unsafe during pregnancy or breastfeeding. It is formulated to be safe from birth and is approved for use on newborns, making it one of the safest cleansers available for expectant and nursing mothers.
Use with caution. The formula contains Aquaphilus Dolomiae Ferment Filtrate, a ferment-derived ingredient that could theoretically feed Malassezia yeast. However, because this is a rinse-off product with very short skin contact time, the actual risk is considered low. If you are highly sensitive to fungal acne triggers, patch test first or consider an alternative cleanser without ferment-based ingredients.
Yes, absolutely. This is a rinse-off cleanser with a neutral, non-active formula, so it will not interact negatively with any leave-on actives like retinol, vitamin C, AHAs, or BHAs. In fact, its gentle, non-stripping nature makes it an excellent cleanser to pair with potentially irritating actives, as it won't compound dryness or sensitivity.
This cleanser is specifically formulated for reactive, irritated, and compromised skin. It excels for sensitive, dry, and post-procedure skin. It is also suitable for combination and oily skin types, though those with very oily skin may prefer a slightly more thorough cleanser for daily use. It works well for all ages, from newborns to adults.
Soothing and comfort are noticed immediately from the first use — 96% of users in clinical studies felt their skin was soothed right away. Antibacterial purifying effects occur within 5 minutes. Visible improvements in irritation and redness typically appear within 1–2 weeks of consistent use. Full skin barrier support benefits develop over 3–4 weeks.
This product is your first step — the cleanser. Use it morning and/or evening on wet skin, lather, and rinse. If you wear heavy makeup or sunscreen, you can use an oil-based cleanser first (double cleansing method), then follow with this gel as your second cleanser. After cleansing, proceed with toner, serum, moisturizer, and sunscreen (AM).
This cleanser has a very low comedogenic rating of 1/5. It is a water-based, oil-free, silicone-free rinse-off formula with gentle surfactants. Since it does not remain on the skin, pore-clogging risk is minimal. The Avène Cicalfate+ line is labeled non-comedogenic and is suitable for acne-prone skin.
The Period After Opening (PAO) is 12 months. Once opened, use the product within one year for optimal efficacy and safety. If used twice daily on the face only, the 200ml bottle typically lasts 2–3 months. For full-body use, expect approximately 3–4 weeks of use per bottle.
Verdict: Avène Cicalfate+ Purifying Cleansing Gel is an exceptional gentle cleanser for anyone with reactive, irritated, or post-procedure skin. Its minimalist 15-ingredient formula, exclusive postbiotic [C+-Restore], and Copper-Zinc antibacterial complex deliver genuine soothing and purifying benefits backed by clinical data. The SLS-free surfactant system is among the gentlest available, making it safe for newborns through adults — a true whole-family product. The only drawbacks are the relatively small 200ml size for body use, limited availability in some markets, and the presence of a ferment filtrate that may concern those strictly avoiding fungal acne triggers. For anyone recovering from dermatological procedures, managing skin sensitivity, or simply wanting a clean-ingredient, non-drying daily cleanser from a trusted French pharmacy brand, this is a top-tier choice.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 0 |
Disodium Coco-Glucoside Citrate
Emulsifying
|
|
|
| 1 |
Decyl Glucoside
Surfactant, Emulsion Stabilising, Cleansing
|
|
|
| 1 |
Sodium Cocoamphoacetate
Hair Conditioning, Sufactant, Foam Boosting, Foaming
|
|






