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Daily Serum

Daily Serum

Product Description

A breakthrough exosome serum harnessing patented Renewosomeβ„’ technology to deliver over 7.5 billion platelet-derived exosomes per pump. Clinically proven to reduce fine lines, redness, and brown spots while improving skin luminosity and overall texture in just 6 weeks.

πŸ‡ΊπŸ‡Έ Medical-Grade Skincare Β· Made in Rochester, MN, USA
βœ” Clinically Proven βœ” Fragrance-Free βœ” Paraben-Free βœ” Cruelty-Free βœ” All Skin Types βœ” Non-Comedogenic πŸ† Best Exosome Serum 2024 - NewBeauty
Pregnancy Safe
Caution ⚠️
Fungal Acne Safe
Yes βœ”
Comedogenic Rating
0/5
πŸ’§
Size
30ml / 1 fl oz
πŸ”¬
Key Tech
Renewosomeβ„’
✨
Exosomes
7.5B per pump
⏱️
Results
6 weeks
πŸ“¦
Pumps
~128 per bottle

✨ Texture & Feel

πŸ’§
Consistency
Lightweight Gel
πŸ‘ƒ
Scent
Fragrance-Free
⏱️
Absorption
2-5 minutes
🎯
Finish
Dewy Glow
🧬

Platelet-Derived Exosomes

First-of-its-kind technology using human platelet extract safely sourced from FDA-regulated US blood banks for superior biocompatibility.

πŸ”„

Cellular Renewal

Trillions of Renewosomesβ„’ deliver growth factors and antioxidants to support skin's natural collagen and elastin production.

πŸ’§

Deep Hydration

Moisturizing formula with glycerin and oat kernel extract provides lasting hydration while improving luminosity.

🌿

Gentle Formula

Hypoallergenic, fragrance-free formula suitable for all skin types including sensitive and reactive skin.

πŸ›‘οΈ Safety & Compatibility

⚠️
Pregnancy & Breastfeeding

Not recommended. Insufficient clinical data exists for use during pregnancy or breastfeeding. Consult your physician before use.

βœ…
Fungal Acne (Malassezia) Safe

Formula is free from fatty acids, esters, ferments, and oils that feed malassezia yeast. Safe for fungal acne-prone skin.

βœ…
Sensitive Skin Approved

Hypoallergenic, fragrance-free formula tested for sensitive skin. No harsh irritants or common allergens.

βœ…
Retinol & Vitamin C Compatible

Can be used alongside retinol, retinoids, and vitamin C. May actually enhance efficacy of other actives when layered properly.

ℹ️
Ethical Sourcing

Platelets safely and ethically sourced from compliant FDA-regulated blood banks in the United States with rigorous testing for purity.

βœ…
No Sun Sensitivity

Does not cause photosensitivity. Can be used morning or night. Still recommended to use daily SPF.

πŸ”¬ Ingredient Breakdown

🧬 Human Platelet Extract (Renewosomeβ„’) Patented

The star ingredient - platelet-derived exosomes containing over 800 growth factors, cytokines, and potent antioxidants. Acts as cellular messengers to signal skin repair and regeneration.

  • Source: Ethically sourced from FDA-regulated US blood banks
  • Clinical Study: Published in Aesthetic Surgery Journal showing statistically significant reduction in facial redness
  • Potency: 6x more powerful than 10% medical-grade topical Vitamin C without irritation
✨
Unlike stem cell-derived exosomes, platelet-derived exosomes are more stable, ethical, and biologically compatible with human skin.

πŸ’§ Glycerin Humectant Proven

One of the most effective and well-researched moisturizing ingredients. Draws water into the skin to maintain hydration and strengthen the skin barrier.

  • Function: Humectant that attracts and retains moisture
  • Safety: Considered safe for all skin types including sensitive skin

🌾 Avena Sativa (Oat) Kernel Extract Soothing

Natural anti-inflammatory and skin-soothing ingredient known for calming irritation and redness. Helps strengthen the skin barrier.

  • Benefits: Reduces inflammation, soothes irritation, provides antioxidant protection
  • Safe for: Sensitive, reactive, and compromised skin

πŸ§ͺ Silanetriol Firming

Silicon-based compound that helps improve skin firmness and elasticity. Supports structural integrity of the skin matrix.

  • Function: Promotes skin firmness and elasticity
  • Texture: Lightweight, non-greasy finish

13 ingredients

Purified Water, Glycerin, Pentylene Glycol, Polyacrylate Crosspolymer-6, Human Platelet Extract, Caprylyl Glycol, 1,2-Hexanediol, Hydrolyzed Gelatin, Silanetriol, Arginine, Sodium Benzoate, Avena Sativa (Oat) Kernel Extract, Potassium Sorbate

FREE FROM: Parabens, Fragrances, Sulfates, Phthalates, Mineral Oil, Silicones, Alcohol, Artificial Colors, Gluten, Retinoids, Essential Oils, Fatty Acids, Ferments

πŸ”„ Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Daily Serum
4
Treatment Serum
5
Moisturizer
6
Sunscreen (AM)

Apply Plated Daily Serum FIRST on clean, product-free skin for maximum exosome absorption. Allow to fully dry before layering other products.

πŸ“ How to Use

1

Cleanse Thoroughly

Start with clean, dry skin. Remove all makeup, sunscreen, and impurities for optimal absorption.

2

Apply One Pump

Dispense one pump for face. Add an additional pump for neck and chest if desired. Avoid direct eye contact.

3

Wait for Absorption

Allow serum to fully absorb and dry completely (2-5 minutes) before applying other products. This ensures maximum exosome penetration.

4

Continue Your Routine

Once dry, layer your other serums, moisturizer, and SPF (morning). Can be used AM or PM, once daily.

πŸ‘€ Who Is It For?

βœ… Perfect for you if:

  • You want to address early signs of aging (fine lines, dullness)
  • You have redness, rosacea, or sensitive skin
  • You're looking for a "glow" and luminosity boost
  • You want to maintain results after using Plated Intense
  • You prefer pre-juvenation over correction
  • You have uneven skin tone or texture concerns
  • You want a gentle yet effective anti-aging serum

❌ Consider alternatives if:

  • You have deep wrinkles or significant laxity (try Plated Intense)
  • You are pregnant or breastfeeding
  • You need immediate dramatic results
  • You're on a tight budget under $100
  • You have active acne that needs treatment (add targeted actives)

🎯 Skin Type Compatibility

Oily Skin β˜…β˜…β˜…β˜…β˜… Excellent

Lightweight gel texture absorbs quickly without adding shine or greasiness. Non-comedogenic formula won't clog pores.

Dry Skin β˜…β˜…β˜…β˜…β˜† Good

Provides excellent hydration with glycerin base. May need additional moisturizer on top for very dry skin types.

Combination Skin β˜…β˜…β˜…β˜…β˜… Excellent

Balances well across different face zones. Hydrates dry areas without overwhelming oily T-zone.

Sensitive Skin β˜…β˜…β˜…β˜…β˜… Excellent

Fragrance-free, hypoallergenic formula specifically designed to calm redness and irritation. Clinically tested for sensitive skin.

Acne-Prone Skin β˜…β˜…β˜…β˜…β˜… Excellent

Non-comedogenic (0/5 rating), fungal acne safe formula. Free from pore-clogging ingredients and acne triggers.

Mature Skin β˜…β˜…β˜…β˜…β˜† Good

Great for maintenance and glow. For more significant aging concerns, consider starting with Plated Intense first.

πŸ“ˆ Results Timeline

Week 1-2

Immediate Hydration & Glow

Skin feels more hydrated, plump, and luminous. Many users notice an immediate "glow" effect and softer texture.

85% noticed improved hydration
Week 3-4

Reduced Redness & Calmer Skin

Visible reduction in facial redness and irritation. Skin appears calmer and more even-toned.

78% reported less redness
Week 6

Clinical Results Visible

Statistically significant improvement in fine lines, wrinkles, redness, and brown spots based on clinical trials. Texture noticeably smoother.

Clinical study milestone
Week 8-12

Cumulative Benefits

Progressive improvement continues. Skin firmness, elasticity, and overall radiance continue to improve with consistent use.

Results continue improving through 24 weeks

⭐ Ratings by Platform

🏠 Plated Skin Science (Official)
β˜…β˜…β˜…β˜…β˜… 4.9
Rating
500+
Reviews
⚠️ Main complaint: Price point is high for some budgets
πŸ₯ Mayo Clinic Store
β˜…β˜…β˜…β˜…β˜… 5.0
Rating
Featured
Status
⚠️ Main feedback: Some prefer Intense for more dramatic results
πŸ’„ LAZ Skincare
β˜…β˜…β˜…β˜…β˜… 4.9
Rating
19
Reviews
⚠️ Main complaint: Refill pump mechanism can be tricky
✨ Art of Skincare
β˜…β˜…β˜…β˜…β˜† 4.7
Rating
11
Reviews
⚠️ Main complaint: Some want more visible firming for mature skin

βš–οΈ Pros & Cons

βœ… Praised

  • Visible glow and luminosity improvement
  • Significantly reduces redness and irritation
  • Lightweight, fast-absorbing formula
  • Clinically proven with published studies
  • Compatible with retinol and vitamin C
  • Fragrance-free and hypoallergenic
  • Award-winning technology
  • Refillable packaging option

❌ Criticized

  • Premium price point ($258/30ml)
  • Less potent than Intense for mature skin
  • Refill mechanism can be confusing
  • Not recommended during pregnancy
  • Requires patience (6 weeks for results)
  • Limited retail availability

πŸ’° Budget-Friendly Alternatives (Dupes)

55% Match
The Inkey List 15% Vitamin C + EGF Serum
$17.99 Budget Pick

Plant-derived EGF (Epitensive) with vitamin C. Much simpler formula without platelet-derived exosomes. Good for brightening but lacks the regenerative power of human-derived growth factors.

60% Match
Bioeffect EGF Serum
$179 Similar Price

Plant-based EGF derived from barley. Clean 7-ingredient formula. Lacks the diverse growth factor complex of platelet-derived exosomes but excellent for those preferring plant-based options.

45% Match
Reviv Serums Ultimate Serum
$129 Budget Pick

Contains fibroblast and bone marrow stem cell exosomes plus peptides. More ingredients but less clinical backing. Vegan and gluten-free option at lower price point.

πŸ”„ Comparison with Competitors

SkinMedica TNS Advanced+ Serum

$295
Key Technology TNS-MR Growth Factors
Size 28.4g (1 fl oz)
Growth Factor Source Human Fibroblast Conditioned Media
Clinical Studies Extensive Clinical Data
Best For Sagging Skin, Deep Wrinkles

Bioeffect EGF Serum

$179
Key Technology Barley-Derived EGF
Size 15ml (0.5 fl oz)
Growth Factor Source Plant-Based (Barley)
Clinical Studies Clinical Backing
Best For Plant-Based Preference, Minimalists

Plated Intense Serum

$258
Key Technology Platelet-Derived Exosomes (Higher Conc.)
Size 15ml (0.5 fl oz)
Growth Factor Source Human Platelets
Clinical Studies Published in Peer-Reviewed Journals
Best For Mature Skin, Significant Concerns

πŸ“¦ Storage & Shelf Life

πŸ“…
Period After Opening (PAO)

12 months after opening. Airless pump system helps preserve formula integrity.

🏠
Storage

Store at room temperature (10-35Β°C / 50-95Β°F). Keep away from direct sunlight and extreme temperatures.

πŸ“¦
Packaging

Airless pump dispenser with refillable cartridge system. Eco-friendly design with Silver Ring gasket for proper seal.

✈️
Travel Friendly

Yes, 30ml is under TSA 100ml liquid limit. Airless pump prevents leakage during travel.

❓ Frequently Asked Questions

Not recommended. While the formula does not contain many harmful ingredients like retinoids or chemical sunscreens, there is insufficient clinical data to support claims of safety during pregnancy and breastfeeding. Plated Skin Science recommends consulting with your physician before using any of their products during pregnancy or breastfeeding. Most dermatologists advise erring on the side of caution with exosome products during this time.

Yes! Plated Daily Serum is fungal acne safe. The formula is free from fatty acids, esters, ferments, polysorbates, and oils that feed malassezia yeast. The lightweight gel formula relies on humectants like glycerin and pentylene glycol rather than occlusive oils, making it an excellent choice for those prone to fungal acne or malassezia folliculitis.

Yes! According to dermatologists and the brand, Plated Daily Serum can be used alongside retinol, retinoids, vitamin C, AHAs, and BHAs. In fact, research suggests that exosomes may enhance the efficacy of these actives. For best results, always apply Plated first on clean skin, allow it to fully dry (2-5 minutes), then layer your other treatments. There's no sun sensitivity from this product, so you can use it morning or night.

Plated Daily Serum is formulated for all skin types including oily, dry, combination, sensitive, and acne-prone skin. It's particularly excellent for those with sensitive or rosacea-prone skin due to its redness-reducing and calming properties. The lightweight, non-comedogenic formula works well for oily and acne-prone skin, while the hydrating glycerin base benefits dry skin types. It's ideal for those in their late 20s-40s focusing on prevention and early aging signs.

Most users notice improved hydration and a subtle glow within the first 1-2 weeks. Clinical studies show statistically significant improvements in wrinkles, redness, and brown spots at 6 weeks of consistent daily use. Results continue to improve progressively through 24 weeks. For those with more significant aging concerns, consider starting with Plated Intense for 6-12 weeks before transitioning to Daily for maintenance.

Apply Plated Daily Serum as the FIRST step after cleansing, before any other products. The exosomes work most effectively with direct access to clean, product-free skin. After cleansing (and optional toner), apply one pump to face, let it fully absorb and dry (2-5 minutes), then continue with your other serums, moisturizer, and SPF. Use once daily, either morning or night.

No, Plated Daily Serum is non-comedogenic with a rating of 0/5. The formula is specifically designed to be lightweight and free from pore-clogging ingredients. It contains no oils, heavy occlusives, or known comedogenic ingredients. The airless pump delivery system also ensures hygienic dispensing without contamination risk. It's safe for acne-prone skin and won't trigger breakouts.

Plated Daily Serum has a 12-month Period After Opening (PAO). The airless pump system helps preserve the formula's integrity by preventing air exposure and contamination. Store at room temperature away from direct sunlight. Each 30ml bottle contains approximately 128 pumps, which at once-daily use provides about 4 months of supply per bottle.

β˜…β˜…β˜…β˜…β˜†
4.5 out of 5

Verdict: Plated Daily Serum represents cutting-edge exosome technology backed by real clinical science. It excels at delivering visible improvements in skin luminosity, redness reduction, and overall skin health with a gentle, well-tolerated formula. The premium price is justified by the patented Renewosomeβ„’ technology and ethically-sourced platelet-derived exosomes that outperform plant-based alternatives. Best suited for those seeking a daily maintenance serum focused on glow, hydration, and prevention rather than dramatic correction. For mature skin with significant concerns, consider starting with Plated Intense before transitioning to Daily. An excellent investment for skincare enthusiasts willing to pay for innovation.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

Awesome, I Understand!

Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging Β«promisesΒ» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

Awesome, I Understand!

Notable Effects & Ingredients

brightening Brightening from 1 ingredient(s):
Glycerin
wound Promotes Wound Healing from 2 ingredient(s):
Glycerin Arginine
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

Awesome, I Understand!

Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
1
oily-skin Oily/Acne-Prone Skin
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
80% 20%

Product ingredient list

Showing first 5 of 10 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
2 A
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
brightening Brightening
Promotes Wound Healing
Hydrating
1 A
Pentylene Glycol
Solvent, Skin Conditioning
1 Unknown
Polyacrylate Crosspolymer-6
Viscosity Controlling, Emulsion Stabilising
0 Unknown
Human Platelet Extract
Skin Conditioning
VIEW ALL INGREDIENTS