Hyaluron Activ B3 Multi-intensive Night Cream
Hyaluron Activ B3 Multi-intensive Night Cream
Product Description
Product overview
A multi-intensive restorative night cream featuring 0.1% retinaldehyde, 6% niacinamide, pure hyaluronic acid, and Haritaki extract to combat cellular aging while you sleep. Wake up to smoother, firmer skin with visibly reduced wrinkles after just 2 weeks of use.
Retinaldehyde Power
Contains 0.1% retinal, which converts to retinoic acid 11x faster than standard retinol for accelerated anti-aging results.
Texture & feel
SENSORYRetinaldehyde Power
Contains 0.1% retinal, which converts to retinoic acid 11x faster than standard retinol for accelerated anti-aging results.
Cellular Senescence Science
6% niacinamide targets senescent "zombie cells" that accelerate aging, prolonging cellular lifespan by up to 50%.
Dual-Weight Hyaluronic Acid
High molecular weight hydrates the surface while low molecular weight replenishes deeper skin layers for plumping effect.
Haritaki Extract
Ayurvedic "fruit of longevity" protects natural hyaluronic acid in skin and provides powerful antioxidant benefits.
Safety & compatibility
SAFENOT recommended. Contains retinaldehyde, a vitamin A derivative. Avoid all retinoids during pregnancy and nursing as a precaution.
NOT safe. Contains shea butter, safflower oil, sunflower oil, and fatty alcohols that can feed malassezia yeast.
Formulated for sensitive skin with Avène Thermal Spring Water. Start with every-other-night use to build tolerance.
Retinoids increase photosensitivity. Always use SPF 30+ during the day when using this product at night.
Some tingling may occur in first weeks as skin adjusts. Space out applications if discomfort persists.
Paraben-free, silicone-free, and formulated to minimize allergic reactions. Contains fragrance.
Ingredient breakdown
INGREDIENTSRetinaldehyde (Retinal) 0.1%Gold Standard
Direct precursor to retinoic acid, converting in just one step within the skin. Works up to 11x faster than retinol while being gentler than prescription tretinoin.
- Mechanism: Increases epidermal renewal and stimulates collagen, elastin, and natural hyaluronic acid production
- Clinical Evidence: Proven effective in treating photoaging, fine lines, and uneven texture
- Avène Study: 0.1% retinal + glycolic acid showed excellent tolerability across 1,709 patients over 90 days
Niacinamide (Vitamin B3) 6%Proven
Powerhouse multitasker that increases cell lifespan by up to 50% according to Avène research. This unprecedented 6% concentration is among the highest in anti-aging products.
- Anti-Senescence: Targets "zombie cells" that spread aging signals throughout skin
- Barrier Support: Strengthens skin barrier and reduces transepidermal water loss
- Brightening: Reduces dark spots and improves overall skin tone and texture
Sodium Hyaluronate Multi-WeightProven
100% pure, natural hyaluronic acid in both high and low molecular weights for comprehensive hydration at multiple skin depths.
- High Molecular Weight: Forms protective film on skin surface, preventing moisture evaporation
- Low Molecular Weight: Penetrates deeper to replenish internal hyaluronic acid reserves
- Capacity: Can hold up to 1000x its weight in water
Terminalia Chebula (Haritaki) ExtractPromising
Known as the "King of Medicine" in Ayurveda, this fruit extract provides powerful antioxidant protection and helps preserve the skin's natural hyaluronic acid.
- HA Protection: Inhibits hyaluronidase enzyme that breaks down natural hyaluronic acid
- Antioxidant: Rich in polyphenols to combat free radical damage
- Sebum Regulation: Helps balance oil production
AdenosineProven
Naturally occurring in every cell of the body, adenosine smooths wrinkles and improves skin firmness through collagen stimulation.
- Anti-Wrinkle: Clinically proven to reduce appearance of fine lines
- Firming: Supports tissue repair and improves skin elasticity
26 ingredients
Avene Thermal Spring Water (Avene Aqua), Caprylic/Capric Triglyceride, Glycerin, Squalane, Butyrospermum Parkii (Shea) Butter, Carthamus Tinctorius (Safflower) Seed Oil, Pentaerythrityl Tetracaprylate/Tetracaprate, Cetearyl Alcohol, Behenyl Alcohol, Niacinamide, C20-22 Alkyl Phosphate, C20-22 Alcohols, Retinal, Sodium Hyaluronate, Terminalia Chebula Fruit Extract, Adenosine, Acacia Senegal Gum, Cetearyl Glucoside, Fragrance (Parfum), Helianthus Annuus (Sunflower) Seed Oil, Red 33 (CI 17200), Sodium Benzoate, Sodium Hydroxide, Tocopherol, Tocopheryl Glucoside, Water (Aqua), Xanthan Gum
Where it fits in your routine
ROUTINEUse PM only. For best results, pair with Avène Hyaluron Activ B3 Serum before application. Always use SPF 30+ the following morning.
How to use
HOW TO USECleanse Thoroughly
Remove makeup and cleanse skin with a gentle cleanser. Pat dry completely before application.
Apply Serum (Optional)
For enhanced results, apply Avène Hyaluron Activ B3 Concentrated Plumping Serum first and allow to absorb.
Dispense 2 Pumps
Press the pump twice to dispense the recommended amount. The orange color is natural from retinaldehyde.
Apply to Face, Neck & Décolleté
Gently massage in upward motions, avoiding the eye area. Allow to fully absorb before lying down.
Start Slowly
Beginners: Use every other night for 2 weeks, then gradually increase to nightly use as tolerated.
Who is it for?
WHOPerfect for you if:
- You're noticing first signs of aging (fine lines, loss of firmness)
- You want a gentler alternative to prescription retinoids
- You have sensitive skin but want retinoid benefits
- You prefer French pharmacy skincare quality
- You want an all-in-one night treatment
- You're ready to commit to consistent PM use
Consider alternatives if:
- You are pregnant or breastfeeding
- You have fungal acne/malassezia folliculitis
- You prefer fragrance-free products
- You want immediate, dramatic results
- You cannot commit to daily SPF use
- You're already using prescription tretinoin
Skin type compatibility
SKIN TYPESIdeal match. Rich yet non-greasy texture provides perfect nourishment without overwhelming skin.
Excellent choice. Shea butter and squalane provide intense moisture while hyaluronic acid deeply hydrates.
Works well but may feel rich. Use sparingly and consider the day cream version for less emollient texture.
Good overall. May want to apply lightly on T-zone. Non-comedogenic formula won't clog pores.
Specifically formulated for sensitive skin. Start with every-other-night use to build tolerance gradually.
Non-comedogenic but contains oils. Not suitable for fungal acne. May help with retinoid purging initially.
Results timeline
MONTH 1-3Immediate Comfort & Glow
Skin feels nourished and cocooned. Wake up to a visible "post-facial" glow with smoother, more relaxed skin appearance.
74% noticed improvementSmoother Texture
Skin becomes noticeably smoother upon waking. Fine lines appear softened. Some may experience mild purging or tingling.
84% noticed smoother skinVisible Firmness
Skin feels firmer and more elastic. Wrinkles begin to appear reduced. Overall skin tone becomes more even and radiant.
79% noticed firmer skinLasting Regeneration
Cumulative effects become significant. Deep wrinkles appear filled. Skin shows long-term regeneration with improved elasticity.
84% long-term satisfactionRatings by platform
516+ REVIEWSPros & cons
BALANCEDPraised
- Noticeable results from first use with "post-facial" glow
- More tolerable than other 0.1% retinal products
- Luxurious, non-greasy texture that absorbs well
- Combines 4 powerful actives in one product
- 97% natural origin, vegan, eco-conscious packaging
- Effective for sensitive skin when introduced gradually
- Vacuum pump maintains formula freshness
- Excellent value compared to premium retinal alternatives
Criticized
- Contains fragrance (not fragrance-free)
- Orange tint may stain pillowcases
- Not suitable for pregnancy/breastfeeding
- Not fungal acne safe
- 40ml may not last long for daily use
- May feel too rich for very oily skin
- Initial adjustment period with possible tingling
- Requires consistent SPF use during the day
Budget-friendly alternatives (dupes)
DUPESUses a gentler retinoid (HPR) instead of retinaldehyde. Lacks niacinamide and Haritaki but still effective for beginners. Much more affordable entry point.
Uses retinol (0.3%) instead of retinaldehyde, so works more slowly. Also formulated for sensitive skin. Lighter texture, may need additional moisturizer.
Contains encapsulated retinol with ceramides and niacinamide. Fragrance-free and gentle. Lighter serum texture rather than rich cream.
Contains 0.05% retinaldehyde. Excellent affordable retinal option with good supporting ingredients. Lower concentration but highly effective.
Comparison with competitors
SIDE-BY-SIDEStorage & shelf life
12 MONTHS12 months after opening. Note the date you first opened the product.
Store in a cool, dry place away from direct sunlight. Keep lid tightly closed to protect retinaldehyde from oxidation.
Glass jar with vacuum pump dispenser. Twist-lock mechanism protects formula from air exposure and contamination.
Yes, 40ml is under TSA 100ml limit. Glass jar is sturdy but consider protective case for checked luggage.
Frequently asked questions
FAQNo, this product is NOT recommended during pregnancy or breastfeeding. It contains retinaldehyde (retinal), which is a vitamin A derivative. While topical retinoids have minimal systemic absorption, most medical professionals advise avoiding all forms of retinoids during pregnancy and nursing as a precautionary measure. Consider bakuchiol-based alternatives during this time.
No, this product is NOT fungal acne safe. It contains several ingredients that can feed malassezia yeast, including shea butter, safflower seed oil, sunflower seed oil, and fatty alcohols (cetearyl alcohol, behenyl alcohol). If you have fungal acne or are prone to it, consider fungal-safe alternatives like Avène Tolérance Extrême products or other FA-safe retinoid options.
This cream already contains 0.1% retinaldehyde, so do NOT layer additional retinol or retinoids. For vitamin C: use vitamin C in your AM routine and this cream at night. For AHAs/BHAs: avoid using them on the same nights as this cream to prevent irritation. You can alternate nights (acids one night, this cream the next) once your skin has adjusted.
This cream is best suited for normal, dry, and combination skin types showing early to moderate signs of aging. It's particularly excellent for those with sensitive skin who want retinoid benefits without harsh irritation. Those with very oily skin may find it too rich and might prefer the day cream version or a lighter retinal serum.
Many users notice an immediate "post-facial" glow and smoother skin from the first use. Clinical studies show 84% noticed smoother skin after 2 weeks, and 79% reported firmer skin in the same timeframe. For significant wrinkle reduction and lasting regeneration benefits, allow 4-12 weeks of consistent use.
Apply as your last step in your PM routine, after cleansing, toning, serums, and eye cream. For optimal results, use after Avène Hyaluron Activ B3 Concentrated Plumping Serum. This is a night-only product. Always follow with SPF 30+ sunscreen the next morning, as retinaldehyde increases sun sensitivity.
Avène states this product is non-comedogenic. However, it contains shea butter, safflower oil, and fatty alcohols which have low-moderate comedogenic potential. Most users with acne-prone skin tolerate it well, but if you're extremely clog-prone, patch test first. Comedogenic rating: approximately 2/5 (low-moderate).
The PAO (Period After Opening) is 12 months. The 40ml jar typically lasts 2-3 months with nightly use (2 pumps per application). The vacuum pump packaging helps maintain formula integrity by minimizing air exposure. Store away from direct sunlight and heat to preserve the retinaldehyde effectiveness.
Verdict: Avène Hyaluron Activ B3 Multi-Intensive Night Cream is an exceptional choice for those seeking an effective yet gentle introduction to retinaldehyde. The combination of 0.1% retinal with 6% niacinamide and dual-weight hyaluronic acid delivers visible anti-aging results without the harsh irritation of stronger retinoids. Particularly impressive for sensitive skin types, it offers French pharmacy quality at a reasonable price point compared to premium alternatives like Medik8 or Allies of Skin. The main drawbacks are the fragrance and unsuitability for fungal acne or pregnancy. For most users over 30 seeking to address fine lines, firmness, and overall skin regeneration, this night cream delivers on its promises.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Caprylic/Capric Triglyceride
Solvent, Skin Conditioning, Masking, Perfuming, Emollient
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 1 |
Squalane
Skin Conditioning, Emollient, Hair Conditioning, Refatting
|
Hydrating
|
|
| 0 |
Butyrospermum Parkii Butter
Skin Conditioning
|
Hydrating
|
|
| 0 |
Carthamus Tinctorius Seed Oil
Masking, Skin Conditioning
|
Hydrating
|









