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Hyaluronic Acid & Peptide Serum

Hyaluronic Acid & Peptide Serum

Product Description

Product overview

Made in Various INTERNATIONAL

A lightweight, fast-absorbing hydrating serum powered by five types of hyaluronic acid, Matrixyl 3000 peptides, niacinamide, and caffeine. Designed for all skin types, it plumps, revitalizes, and brightens the complexion while supporting collagen production and oil balance.

Vegan Cruelty-Free Fragrance-Free Paraben-Free Alcohol-Free Silicone-Free Oil-Free Dermatologically Tested Microplastic-Free
Pregnancy
Yes
Fungal Acne
Caution
Comedogenic
1/5
Size
30ml / 1.01 fl oz
Type
Serum
Concern
Hydration & Anti-Aging
Usage
AM & PM
Skin Type
All Skin Types
Why it's different

5 Types of Hyaluronic Acid

Multi-molecular weight HA complex including sodium hyaluronate, hydrolyzed HA, and crosspolymer HA for deep, lasting hydration at every skin layer.

01

Texture & feel

SENSORY
Consistency
Lightweight Gel
Scent
Fragrance-Free
Absorption
15-30 seconds
Finish
Dewy & Plump

5 Types of Hyaluronic Acid

Multi-molecular weight HA complex including sodium hyaluronate, hydrolyzed HA, and crosspolymer HA for deep, lasting hydration at every skin layer.

Matrixyl 3000 Peptides

Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 work together to stimulate collagen production and reduce inflammation for firmer, smoother skin.

Niacinamide (Vitamin B3)

Balances oil production, minimizes pores, brightens uneven skin tone, and strengthens the skin barrier for a healthier complexion.

Caffeine & Aloe Vera

Caffeine energizes and depuffs the skin while aloe vera calms, soothes, and provides antioxidant protection against environmental stressors.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

Contains no retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe during pregnancy and breastfeeding. Always consult your doctor.

Fungal Acne (Malassezia) — Use with Caution

Contains Polysorbate 20 (emulsifier) and palmitoyl-based peptides which may feed malassezia yeast in some individuals. Patch test recommended if you are prone to fungal acne.

Low Comedogenic Risk (1/5)

Oil-free, silicone-free, lightweight formula. No comedogenic oils or heavy emollients. Very unlikely to clog pores.

Sensitive Skin Friendly

Free from fragrance, alcohol, parabens, sulfates, and common allergens. Dermatologically tested in Europe. Patch test recommended for very reactive skin.

Compatible with Retinol

Can be layered with retinol products. Apply this serum first, let it absorb, then follow with retinol. The hydrating formula helps buffer potential retinol irritation.

Compatible with Vitamin C & AHA/BHA

No conflicting active ingredients. Can be used alongside vitamin C serums and chemical exfoliants. Apply acids first, then layer this serum on top for hydration.

03

Ingredient breakdown

INGREDIENTS

5-Type Hyaluronic Acid ComplexProven

A multi-molecular weight hyaluronic acid system combining Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, and Hydrolyzed Glycosaminoglycans. Each form targets different skin depths for comprehensive hydration from the surface to the deeper layers.

  • Hydrolyzed HA: Low molecular weight penetrates deeper layers for improved elasticity and wrinkle reduction.
  • Sodium Hyaluronate: Salt form of HA that binds up to 1,000x its weight in water for intense surface hydration.
  • Crosspolymer HA: Cross-linked form with 5x the water-binding capacity of standard HA, providing long-lasting moisture.
  • Clinical evidence: A 12-week study showed HA serums improved skin texture (79%), lines/wrinkles (50%), and skin tone (44%).
Multi-weight HA is superior to single-type HA formulas — it hydrates at every depth of the skin simultaneously.

Matrixyl 3000 (Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7)Proven

The world's most popular peptide complex. Palmitoyl Tripeptide-1 is a collagen fragment that signals the skin to produce new collagen, while Palmitoyl Tetrapeptide-7 reduces inflammation by suppressing interleukin-6 (IL-6) production. Together they form Matrixyl 3000.

  • Collagen Stimulation: Palmitoyl Tripeptide-1 (GHK peptide) mimics a collagen breakdown fragment, triggering the skin to produce fresh collagen.
  • Anti-Inflammatory: Palmitoyl Tetrapeptide-7 reduces IL-6 signaling, helping calm chronic low-grade skin inflammation linked to aging.
  • Clinical data: Matrixyl 3000 has been shown to reduce wrinkle depth and volume in double-blind placebo-controlled studies.
Palmitoyl base (fatty acid) may be a concern for those with fungal acne/malassezia folliculitis.

Niacinamide (Vitamin B3) ~2-5%Proven

A multitasking powerhouse ranked 4th on the ingredient list. Niacinamide improves skin barrier function, reduces sebum production, minimizes pore appearance, fades hyperpigmentation, and has anti-inflammatory properties.

  • Oil Control: Studies show 2% niacinamide significantly reduces sebum production after 2-4 weeks of use.
  • Brightening: Inhibits melanosome transfer to reduce dark spots and uneven skin tone over time.
  • Barrier Support: Boosts ceramide and fatty acid production in the skin, strengthening the moisture barrier.

CaffeinePromising

A potent antioxidant and vasoconstrictor that energizes the skin, reduces puffiness, and protects against UV-induced damage. Helps improve microcirculation for a healthier, more vibrant complexion.

  • Antioxidant: Neutralizes free radicals and has been shown to protect against UV-induced skin damage.
  • De-puffing: Constricts blood vessels to reduce under-eye puffiness and dark circles when applied topically.

Allantoin + Aloe Barbadensis Leaf JuiceProven

A soothing duo that calms irritation, promotes skin healing, and provides lightweight hydration. Allantoin is a well-known skin protectant, while aloe vera offers anti-inflammatory and antioxidant benefits.

  • Soothing: Allantoin promotes cell regeneration and is classified as a skin protectant by the FDA.
  • Calming: Aloe vera contains polysaccharides that reduce redness and irritation, making it ideal for sensitive skin.

Sodium PCAProven

A natural component of the skin's own Natural Moisturizing Factor (NMF). Sodium PCA is a powerful humectant that helps the skin retain moisture, keeping it soft, supple, and properly hydrated.

  • NMF Component: Naturally present in the stratum corneum, making it highly biocompatible and effective.
  • Humectant: Draws moisture from the environment into the skin, working synergistically with hyaluronic acid.

25 ingredients

Aqua, Butylene Glycol, Glycerin, Niacinamide, Glyceryl Acrylate/Acrylic Acid Copolymer, Propylene Glycol, PVM/MA Copolymer, Propanediol, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Polysorbate 20, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Phenoxyethanol, Sodium PCA, Carbomer, Sodium Hydroxide, Caffeine, Xanthan Gum, Aloe Barbadensis Leaf Juice, Allantoin, Benzoic Acid

FREE FROM: Parabens, Sulfates, Alcohol, Fragrance/Perfume, Silicones, Oils, Mineral Oil, Microplastics, Gluten, Common Allergens, Harsh Alcohols, Dyes/Colorants
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
This Serum
4
Moisturizer
5
Eye Cream
6
Sunscreen (AM)

Use morning and night. Apply on damp skin for best absorption. Can also be used in the eye area. Works as an excellent primer base before makeup.

05

How to use

HOW TO USE
1

Cleanse & Prep

Wash your face with a gentle cleanser. Lightly pat with a towel leaving the skin slightly damp — this helps hyaluronic acid absorb better.

2

Apply 3-4 Drops

Dispense 3-4 drops onto your fingertips. Gently press and pat the serum into your face, neck, and eye area. Avoid rubbing or pulling the skin.

3

Wait & Layer

Allow 15-30 seconds for the serum to absorb fully. Follow with your moisturizer to lock in hydration. In the morning, finish with sunscreen.

4

Pro Tip: Highlighting Glow

For a dewy, lit-from-within look, apply an extra drop to the high points of the face (cheekbones, brow bone, nose bridge) before or after makeup.

06

Who is it for?

WHO

Perfect for you if:

  • You want deep, multi-layer hydration without heaviness
  • You're looking for anti-aging benefits (fine lines, firmness)
  • You need a lightweight serum for oily or combination skin
  • You want a fragrance-free, vegan, clean formula
  • You need a serum safe for the delicate eye area
  • You want a great primer base for makeup
  • You're pregnant or breastfeeding and need safe hydration

Consider alternatives if:

  • You have confirmed fungal acne (contains Polysorbate 20 and palmitoyl peptides)
  • You need a heavy-duty occlusive for extremely dry/cracked skin
  • You prefer a larger bottle size (this is only 30ml)
  • You want a serum with retinol or vitamin C included
  • You need a treatment serum for active acne or severe hyperpigmentation
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Oil-free, lightweight gel absorbs instantly. Niacinamide actively regulates sebum production. No greasy residue or shine.

Dry Skin
Good

Excellent hydration from 5 types of HA, but dry skin will benefit from layering a richer moisturizer or facial oil on top.

Combination Skin
Excellent

Balances well across different face zones. Hydrates dry patches without adding oil to the T-zone. Niacinamide helps normalize sebum.

Sensitive Skin
Excellent

Fragrance-free, alcohol-free, allergen-free formula with soothing allantoin and aloe. Dermatologically tested. Patch test recommended for very reactive skin.

Acne-Prone Skin
Good

Non-comedogenic (1/5), oil-free, and silicone-free. Niacinamide helps with post-acne marks. Caution for fungal acne due to Polysorbate 20.

Mature Skin
Excellent

Matrixyl 3000 peptides stimulate collagen production. Multi-weight HA plumps fine lines and wrinkles. Ideal for prevention and maintenance.

08

Results timeline

WEEK 8-12
Day 1-3

Instant Hydration Boost

Skin feels immediately plumper, softer, and more hydrated after the first application. Dewy glow is visible right away. Fine dehydration lines appear reduced.

90% noticed immediate hydration
Week 1-2

Improved Skin Texture

Skin starts to feel smoother and more balanced. Niacinamide begins to regulate oil production. Skin tone appears more even and radiant. Redness may start to diminish.

75% noticed smoother texture
Week 4-6

Visible Plumping & Firming

Consistent use allows peptides to begin stimulating collagen production. Fine lines appear less prominent. Skin looks firmer with improved elasticity and a healthy bounce.

65% noticed reduced fine lines
Week 8-12

Cumulative Anti-Aging Benefits

Full benefits of Matrixyl 3000 peptides become apparent. Clinical studies show improvements in skin texture (79%), lines/wrinkles (50%), and skin tone (44%) at the 12-week mark.

79% noticed improved skin texture
09

Ratings by platform

6K+ REVIEWS
Amazon
4.3
Rating
200+
Reviews
Main complaint: Small bottle size (30ml) runs out quickly with twice-daily use
SkinSort
4.7
Rating
25+
Routines
Main complaint: Limited international availability outside of Turkey
Brand Website (creamco.com.tr)
4.8
Rating
1,500+
Reviews
Main complaint: Wish the dropper dispensed more product per squeeze
Trendyol
4.7
Rating
5,000+
Reviews
Main complaint: Some users wish it came in a pump bottle instead of a dropper
10

Pros & cons

BALANCED

Praised

  • 5 types of HA provide multi-depth hydration that feels instant and lasts all day
  • Matrixyl 3000 peptides offer clinically backed anti-aging benefits
  • Clean formula: no fragrance, alcohol, parabens, silicones, or oils
  • Lightweight gel absorbs fast — great under makeup as a primer
  • Safe for eye area, pregnancy, and sensitive skin
  • Vegan and cruelty-free with dermatological testing
  • Excellent value for the ingredient quality
  • Gives a healthy, dewy glow without greasiness

Criticized

  • Only 30ml — runs out in 4-6 weeks with twice-daily use
  • Dropper packaging is less hygienic than airless pump
  • Not fungal acne safe due to Polysorbate 20 and palmitoyl peptides
  • Limited international availability and shipping options
  • No specific active concentrations disclosed on packaging
  • May not be hydrating enough alone for very dry climates or very dry skin
11

Budget-friendly alternatives (dupes)

DUPES
82% Match
Hyaluronic Acid 2% + B5 Serum
$8.90
Budget Pick

Simpler formula with HA and vitamin B5 only — no peptides, niacinamide, or caffeine. Provides solid hydration at a fraction of the price but lacks the anti-aging and oil-balancing benefits of Cream Co.

85% Match
Multi-Peptide + HA Serum
$17.90
Budget Pick

Contains Matrixyl 3000, multiple peptide complexes, and HA in a single serum. More peptide variety but includes probiotics and amino acids. Slightly thicker texture. Very similar overall approach.

72% Match
Advanced Snail 96 Mucin Power Essence
$21.00
Similar Price

Different approach — uses 96% snail mucin instead of HA + peptides. Excellent hydration and skin repair, larger 100ml size, but no peptides or niacinamide. Better for barrier repair, not anti-aging.

68% Match
Hyaluronic Acid Serum
$12.00
Budget Pick

Another Turkish brand with a similar HA-focused formula. Lacks the Matrixyl 3000 peptide complex and caffeine found in Cream Co. Simpler formulation with fewer active ingredients overall.

12

Comparison with competitors

SIDE-BY-SIDE
Multi-Peptide + HA Serum
Key Actives Multi-Peptide + HA + Amino Acids
Size 30ml
Fragrance-Free Yes
Pregnancy Safe Yes
Fungal Acne Safe No
Vegan Yes

Wishful Thirst Trap Juice HA3 + Peptide Serum

Key Actives 3x HA + Peptides + Vitamin E
Size 30ml
Fragrance-Free No (contains Parfum)
Pregnancy Safe Yes
Fungal Acne Safe No
Vegan Yes
Glass Skin Refining Serum
Key Actives Peptides + HA + Niacinamide + Peach Extract
Size 40ml
Fragrance-Free Yes
Pregnancy Safe Yes
Fungal Acne Safe No
Vegan Yes
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store at room temperature in a cool, dry place. Keep away from direct sunlight and heat. Do not use if the seal is broken upon purchase.

Packaging

Glass dropper bottle with pipette — allows precise dispensing of 3-4 drops per application

Travel Friendly

Yes — 30ml is well under the 100ml TSA/airport liquid limit. Compact glass bottle fits easily in any travel bag.

13

Frequently asked questions

FAQ

Yes. This serum contains no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients commonly flagged as unsafe during pregnancy or breastfeeding. The active ingredients — hyaluronic acid, peptides, niacinamide, caffeine, and aloe vera — are all considered safe for use during pregnancy. As always, consult your OB-GYN or dermatologist if you have specific concerns.

Use with caution. The formula contains Polysorbate 20 (an emulsifier) and palmitoyl-based peptides (Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7) which have a fatty acid component that may feed malassezia yeast. If you have confirmed fungal acne or are highly prone to it, consider patch testing first or choosing a fully fungal acne-safe alternative.

Yes, this serum is compatible with all major actives. It contains no conflicting ingredients. For retinol: apply this serum first, let it absorb, then apply retinol — the hydrating base can help buffer retinol irritation. For vitamin C: use vitamin C in the morning and this serum can be layered right after. For AHA/BHA: apply acids first (on dry skin), wait a few minutes, then layer this serum on top for soothing hydration.

This serum is formulated for all skin types — oily, dry, combination, sensitive, and mature. Its oil-free, lightweight gel texture is especially loved by oily and combination skin types, while the 5 types of hyaluronic acid provide enough hydration for dry skin when layered with a moisturizer. The fragrance-free, allergen-free formula makes it suitable for sensitive and reactive skin. Matrixyl 3000 peptides make it an excellent choice for mature or aging skin.

Hydration and a dewy glow are noticeable immediately after the first application. Improved skin texture and balanced oil production typically become evident within 1-2 weeks. For anti-aging benefits like reduced fine lines and improved firmness from peptides, consistent daily use for 4-8 weeks is recommended. Maximum benefits, including visible improvements in wrinkles and skin tone, are typically seen at the 8-12 week mark based on clinical data for similar HA + peptide formulations.

Apply after cleansing and toning, but before moisturizer and sunscreen. The general rule is to apply products from thinnest to thickest consistency. This serum goes in Step 3 of a typical routine: Cleanser → Toner → This Serum → Moisturizer → Sunscreen (AM). Apply on slightly damp skin for best absorption. Use morning and night. It can also be applied to the eye area.

This serum has a comedogenic rating of 1 out of 5, meaning it is very unlikely to clog pores. The formula is completely oil-free, silicone-free, and contains no heavy emollients or waxes. It is also free from common pore-clogging ingredients. Users with oily and acne-prone skin consistently report that it absorbs cleanly without causing breakouts. However, as with any product, individual reactions can vary, so patch testing is always recommended.

The serum has a Period After Opening (PAO) of 12 months. The 30ml bottle typically lasts 4-6 weeks with twice-daily use (3-4 drops per application). Store at room temperature away from direct sunlight and heat. Keep the dropper clean and avoid touching it to your skin to prevent contamination. Do not use if the product changes color, consistency, or smell.

— Skincarisma verdict
4.5 / 5 ★★★★★

Verdict: Cream Co. Hyaluronic Acid & Peptide Serum delivers impressive value with its 5-type hyaluronic acid complex, Matrixyl 3000 peptides, niacinamide, and caffeine — all in a clean, fragrance-free, vegan formula. It excels at multi-layer hydration with legitimate anti-aging benefits backed by clinical research. The lightweight texture, pregnancy-safe profile, and compatibility with all major actives make it incredibly versatile. The only downsides are the small 30ml bottle size and it not being fully fungal acne-safe. For anyone seeking a well-rounded hydrating and anti-aging serum at an affordable price point, this is a standout performer.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 6 ingredient(s):
Niacinamide Hydrolyzed Hyaluronic Acid Hyaluronic Acid Ceramide AP Palmitoyl Tetrapeptide-7 Caffeine
brightening Brightening from 4 ingredient(s):
Glycerin Niacinamide Hydrolyzed Hyaluronic Acid Hyaluronic Acid
wound Promotes Wound Healing from 6 ingredient(s):
Glycerin Niacinamide Sodium Hyaluronate Hydrolyzed Hyaluronic Acid Hyaluronic Acid Allantoin
ache Ache-fighting from 1 ingredient(s):
Niacinamide
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
4 1
oily-skin Oily/Acne-Prone Skin
2
sensitive-skin Sensitive Skin
1
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
47% 13% 39%

Product ingredient list

Showing first 5 of 23 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
1 A
Butylene Glycol
Solvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
Hydrating
2 A
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
brightening Brightening
Promotes Wound Healing
Hydrating
1 A
Niacinamide
Skin Conditioning, Hair Conditioning, Smoothing
brightening Brightening
ache Ache-fighting
anti-aging Anti-Aging
Promotes Wound Healing
Redness
Irritation
Dark Spots
Pores
1 Unknown
Glyceryl Acrylate/Acrylic Acid Copolymer
Humectant, Viscosity Controlling
VIEW ALL INGREDIENTS