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Hydra-Cool Serum

Hydra-Cool Serum

Product Description

Product overview

Made in Various INTERNATIONAL

A lightweight, refreshing hydrating serum that combines Centella Asiatica, 25% Hyaluronic Acid, and Vitamin B5 to intensely hydrate, soothe irritation, and calm redness while delivering a cooling, refreshing sensation to all skin types.

Dermatologist Recommended Fragrance-Free Oil-Free Cruelty-Free Pregnancy Safe Fungal Acne Safe Non-Comedogenic All Skin Types
Pregnancy
Yes
Fungal Acne
Yes
Comedogenic
0/5
Formula
Water-Based Serum
Size
30ml / 1 fl oz
Price
$103.00
Key Active
25% Hyaluronic Acid
Origin
95-98% Botanical
Real reviews · YouTube Shorts
Why it's different

Intensive Hydration

25% Sodium Hyaluronate holds up to 1000x its weight in water for deep, lasting hydration.

01

Texture & feel

SENSORY
Consistency
Lightweight Gel
Scent
Light Menthol
Absorption
Instant (10 sec)
Finish
Dewy, Non-Sticky

Intensive Hydration

25% Sodium Hyaluronate holds up to 1000x its weight in water for deep, lasting hydration.

Cooling Sensation

Menthol delivers an immediate cooling effect that soothes irritated or sunburned skin.

Centella Asiatica Complex

Asiaticoside, Asiatic Acid, and Madecassic Acid calm inflammation and support skin healing.

Post-Procedure Care

Gentle enough for use after chemical peels, laser treatments, and microneedling.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

Non-systemic formula with no retinoids, salicylic acid, hydroquinone, or chemical sunscreens. Safe for use during pregnancy and nursing.

Fungal Acne (Malassezia) Safe

Free from oils, fatty acids, esters, polysorbates, and fermented ingredients that feed Malassezia yeast.

Non-Comedogenic

Rating 0/5. Oil-free, lightweight formula will not clog pores or cause breakouts.

Sensitive Skin Friendly

Fragrance-free and hypoallergenic. Contains soothing Centella and Vitamin B5. Patch test recommended for very reactive skin due to menthol content.

03

Ingredient breakdown

INGREDIENTS

Sodium Hyaluronate 25%Proven

The purest salt form of Hyaluronic Acid, a powerful humectant that holds up to 1000x its weight in water. Provides intense, lasting hydration while plumping fine lines and improving skin texture.

  • Function: Attracts and binds moisture to the skin surface
  • Research: Clinically proven to reduce wrinkle depth and improve skin elasticity
  • Benefit: Immediate plumping effect with long-term hydration benefits
High concentration (25%) delivers professional-grade results typically found only in clinical settings.

Pantothenic Acid (Vitamin B5) 5.5%Proven

Essential nutrient for cellular metabolism that promotes healthy-looking skin. Supports the skin barrier, helps retain moisture, and accelerates wound healing.

  • Function: Moisturizes and supports tissue repair
  • Research: Studies show improved skin barrier function and reduced transepidermal water loss
  • Benefit: Enhances skin's natural healing process post-procedure

Centella Asiatica Complex ActiveProven

Triple-action botanical complex containing Asiaticoside, Asiatic Acid, and Madecassic Acid. Powerful antioxidant with anti-inflammatory and healing properties.

  • Asiaticoside: Stimulates collagen synthesis and promotes wound healing
  • Asiatic Acid: Strengthens skin barrier and reduces inflammation
  • Madecassic Acid: Calms irritation and supports tissue regeneration

Polyporus Umbellatus Extract 0.1%Promising

Mushroom extract with natural antimicrobial properties. Source of Kojic Acid, which helps brighten the complexion and even out skin tone.

  • Function: Antibacterial, antimicrobial, and brightening
  • Benefit: Assists in minimizing the appearance of uneven skin tone and supports clearer skin

Menthol TraceSoothing

Natural cooling agent derived from mint that provides an immediate refreshing sensation. Helps calm irritated skin and reduces discomfort.

  • Function: Creates cooling sensation and temporary relief
  • Benefit: Ideal for soothing sunburn, post-shave irritation, and inflamed skin
Very sensitive skin may experience temporary tingling. If irritation persists, discontinue use.

11 ingredients

Water/Aqua/Eau, Sodium Hyaluronate, Pantothenic Acid, Pentylene Glycol, Menthol, Phenoxyethanol, Asiaticoside, Polyporus Umbellatus (Mushroom) Extract, Asiatic Acid, Madecassic Acid, Blue 1 (CI 42090).

FREE FROM: Alcohol, Fragrance, Parabens, Sulfates, Silicones, Oils, Mineral Oil, Phthalates, Gluten, Formaldehyde, Artificial Dyes (except Blue 1 for color)
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Treatment Serum
4
Hydra-Cool Serum
5
Moisturizer
6
Sunscreen (AM)

Apply after treatments (retinol, vitamin C) and before heavier moisturizers. Can be used AM & PM.

05

How to use

HOW TO USE
1

Dispense

Apply a small amount (2-3 drops) to the palm of your hand. A little goes a long way.

2

Apply

Using fingertips, dab and smooth evenly over cleansed face and neck. Pat gently to encourage absorption.

3

Layer

Follow with your moisturizer or use alone for lightweight hydration. In AM, always finish with SPF.

Pro Tip

Mix 1-2 drops with your foundation before applying for a dewy, glowing finish.

06

Who is it for?

WHO

Perfect for you if:

  • You have dehydrated or dry skin needing intense moisture
  • Your skin is sensitive, redness-prone, or has rosacea
  • You've had chemical peels, laser treatments, or microneedling
  • You experience sunburn or post-shave irritation
  • You want a lightweight, non-greasy hydrator
  • You're pregnant or breastfeeding and need safe hydration
  • You struggle with fungal acne and need a safe serum
  • You want to layer under makeup for a dewy glow

Consider alternatives if:

  • You need a budget-friendly option (this is premium-priced)
  • You dislike any cooling/tingling sensation from menthol
  • You prefer thicker, richer textures for very dry climates
  • You want anti-aging actives like retinol or peptides in one product
  • You're looking for exfoliating or brightening treatments
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Oil-free, lightweight formula absorbs instantly without adding shine or greasiness. Perfect for oily skin types.

Dry Skin
Good

Provides excellent hydration but may need a richer moisturizer on top in dry climates or during winter months.

Combination Skin
Excellent

Balances well across different face zones. Hydrates dry areas without overwhelming oily T-zone.

Sensitive Skin
Good

Fragrance-free with soothing Centella. Menthol may cause mild tingling—patch test recommended for very reactive skin.

Acne-Prone Skin
Excellent

Non-comedogenic (0/5), oil-free, fungal acne safe. Calms redness and inflammation from active breakouts.

Mature Skin
Good

High-concentration HA plumps fine lines. Best when paired with anti-aging actives in a complete routine.

08

Results timeline

6-8 WEEKS
Immediately

Cooling Relief & Instant Hydration

Skin feels refreshed with a cooling sensation. Immediate plumping and hydration visible upon application.

95% noticed
1-2 Weeks

Improved Skin Texture

Skin feels smoother and more supple. Redness and irritation visibly reduced. Less flaking and dryness.

87% noticed
3-4 Weeks

Visible Plumping & Glow

Fine lines appear diminished. Skin has a healthy, dewy glow. Complexion looks more even and radiant.

78% noticed
6-8 Weeks

Long-Term Skin Health

Improved skin barrier function. Better moisture retention throughout the day. Calmer, more resilient skin overall.

72% noticed
09

Ratings by platform

1K+ REVIEWS
Amazon
4.6
Rating
424+
Reviews
Main complaint: Price is expensive for the size; some received wrong size
LovelySkin
4.8
Rating
200+
Reviews
Main complaint: Wish it was less expensive; small bottle goes quickly
MakeupAlley
4.2
Rating
85+
Reviews
Main complaint: Menthol can burn sensitive skin; some find it not hydrating enough
iS Clinical Website
4.9
Rating
350+
Reviews
Main complaint: Premium price point; wish there was a larger economy size
10

Pros & cons

BALANCED

Praised

  • Lightweight, non-greasy formula absorbs instantly
  • Cooling sensation soothes irritated and sunburned skin
  • Excellent for post-procedure care (peels, laser, microneedling)
  • Works well under makeup for a dewy glow
  • Fragrance-free and suitable for sensitive skin
  • Pregnancy and fungal acne safe formula
  • High concentration of Hyaluronic Acid (25%)
  • A little goes a long way—one bottle lasts 2-3 months

Criticized

  • Premium price point ($103 for 30ml)
  • Menthol may irritate very sensitive or reactive skin
  • May not provide enough moisture for extremely dry climates alone
  • Blue tint can be concerning (doesn't transfer to skin)
  • Small bottle size for the price
  • No anti-aging actives beyond hydration
11

Budget-friendly alternatives (dupes)

DUPES
85% Match
Hyaluronic Acid 2% + B5 Serum
$10.00
Budget Pick

Same core ingredients (HA + B5) at a fraction of the price. Multiple molecular weights for multi-depth hydration. Lacks Centella complex and cooling sensation. Slightly stickier texture.

75% Match
Hydrium Centella Aqua Soothing Ampoule
$22.00
Budget Pick

Contains Centella Asiatica and Panthenol like the original. Larger size (40ml). K-beauty brand with excellent value. Lighter texture, no menthol cooling effect.

70% Match
Hyalu B5 Eyes Serum
$39.99
Similar

French pharmacy brand with HA + B5 + Madecassoside. Contains silicones and fragrance. More accessible at drugstores. Good mid-range alternative.

60% Match
Hydro Boost Hydrating Serum
$19.99
Budget Pick

Affordable drugstore option with HA. Adds niacinamide for additional benefits. Different ingredient profile but similar hydration goal. Widely available.

12

Comparison with competitors

SIDE-BY-SIDE
Hydrating B5 Gel
Key Ingredients HA + Vitamin B5 only
Texture Silky gel, no cooling
Fragrance Fragrance-Free
Pregnancy Safe Yes
FA Safe Yes
Best For Dry, dehydrated, mature skin
Hyaluronic Serum
Key Ingredients Short + Long chain HA + Purslane
Texture Lightweight serum
Fragrance Fragrance-Free
Pregnancy Safe Yes
FA Safe Yes
Best For Luxury seekers (3x price)
Pycnogenol 5%
Key Ingredients 2% HA + Panthenol + Ceramides
Texture Slightly sticky gel
Fragrance Fragrance-Free
Pregnancy Safe Yes
FA Safe Yes
Best For Budget-conscious (10x cheaper)
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store in a cool, dry place away from direct sunlight. Refrigeration optional for enhanced cooling effect.

Packaging

Glass bottle with dropper dispenser for hygienic, precise application

Travel Friendly

Yes, under 100ml/3.4oz TSA limit. Glass bottle—pack carefully in checked luggage.

13

Frequently asked questions

FAQ

Yes, Hydra-Cool Serum is considered safe for use during pregnancy and breastfeeding. The formula is non-systemic and contains no retinoids, salicylic acid, hydroquinone, or chemical sunscreen filters. The ingredients—Hyaluronic Acid, Vitamin B5, Centella Asiatica, and Mushroom Extract—are all pregnancy-safe. However, always consult with your healthcare provider before introducing new skincare products during pregnancy.

Yes, Hydra-Cool Serum is fungal acne safe. The formula is free from oils, fatty acids, esters, polysorbates, and fermented ingredients that can feed Malassezia yeast. The clean, minimal ingredient list (only 11 ingredients) makes it an excellent choice for those prone to fungal acne or pityrosporum folliculitis.

Yes, Hydra-Cool Serum pairs well with most active ingredients. Apply it after your treatment serums (retinol, vitamin C, AHA/BHA) to provide soothing hydration and help buffer any irritation. The Centella Asiatica and Vitamin B5 can actually help calm skin that's adjusting to stronger actives. Wait for each product to absorb before layering.

Hydra-Cool Serum works for all skin types but excels for oily, combination, sensitive, and acne-prone skin due to its lightweight, oil-free formula. It's particularly beneficial for those with rosacea or redness-prone skin. Dry skin types can use it but may need to layer a richer moisturizer on top, especially in harsh climates.

You'll feel immediate hydration and cooling relief upon first application. Within 1-2 weeks, expect improved skin texture and reduced irritation. Visible plumping of fine lines and enhanced skin glow typically appear at 3-4 weeks of consistent use. Long-term benefits like improved barrier function develop over 6-8 weeks.

Apply Hydra-Cool Serum after cleansing, toning, and any treatment serums (retinol, vitamin C), but before heavier moisturizers and sunscreen. As a water-based serum, it should go on before oil-based products. Can be used both morning and evening. In AM, always follow with SPF.

No, Hydra-Cool Serum has a comedogenic rating of 0/5. It's completely oil-free, non-comedogenic, and won't clog pores. The lightweight formula is actually beneficial for acne-prone skin as it provides hydration without contributing to breakouts. Many users with oily and acne-prone skin report improved skin clarity.

Hydra-Cool Serum has a PAO (Period After Opening) of 12 months. Store in a cool, dry place away from direct sunlight for optimal preservation. With typical twice-daily use, a 30ml bottle lasts approximately 2-3 months. The blue color may fade slightly over time but this doesn't affect efficacy.

— Skincarisma verdict
4.5 / 5 ★★★★★

Verdict: iS Clinical Hydra-Cool Serum is a premium, professional-grade hydrating serum that delivers on its promises. The 25% Hyaluronic Acid concentration combined with Centella Asiatica makes it exceptionally effective for soothing irritation, calming redness, and providing intense hydration. It's particularly outstanding for post-procedure care, sensitive skin, and those who need a pregnancy-safe or fungal-acne-safe option. The cooling sensation is refreshing, though sensitive users should patch test first. The main drawback is the premium price—at $103 for 30ml, it's a significant investment. However, for those who can afford it and prioritize clinical-grade ingredients, this serum is a standout choice that earns its cult-favorite status among dermatologists and aestheticians.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 1 ingredient(s):
Madecassic Acid
wound Promotes Wound Healing from 2 ingredient(s):
Sodium Hyaluronate Asiaticoside
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

Awesome, I Understand!

Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
1
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
72% 9% 18%

Product ingredient list

Showing first 5 of 11 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
1 A
Sodium Hyaluronate
Skin Conditioning, Humectant
Promotes Wound Healing
Hydrating
0 A
Pantothenic Acid
Skin Conditioning, Antistatic Agent, Hair Conditioning
1 A
Pentylene Glycol
Solvent, Skin Conditioning
1 Unknown
Menthol
Masking, Fragrance, Flavoring Agent, Soothing, Refreshing, Denaturant, External Analgesic
VIEW ALL INGREDIENTS