Madecassoside Blemish Repair Serum
Madecassoside Blemish Repair Serum
Product Description
A lightweight, fast-absorbing serum formulated with 540ppm Madecassoside, 2% Niacinamide, and 4-TECA complex to calm irritated skin, fade post-blemish marks, and strengthen the skin barrier. Clinically proven to improve the look of dark spots and hyperpigmentation in just 2 weeks.
โจ Texture & Feel
4-TECA Complex
Patented blend of Madecassoside, Madecassic Acid, Asiaticoside & Asiatic Acid for comprehensive skin barrier support.
2% Niacinamide
Clinically proven to brighten uneven skin tone and fade post-blemish marks for a more even complexion.
FLEX-SOME Technology
Advanced delivery system that improves absorption of active ingredients deeper into the skin.
Barrier Repair
Ceramide NP and Beta-Glucan strengthen and repair the skin's natural protective barrier.
๐ก๏ธ Safety & Compatibility
No retinoids, salicylic acid, or hydroquinone. Topical Centella Asiatica/Madecassoside is considered safe during pregnancy.
Contains Polyglyceryl-10 Laurate and Jojoba Seed Oil which may not be fungal acne safe. Patch test recommended.
Clinically tested and proven non-comedogenic. German Dermatest certified. Unlikely to clog pores.
Passed primary dermal irritation test on sensitive skin. Non-irritating formula confirmed by dermatologists.
๐ฌ Ingredient Breakdown
๐ฟ Madecassoside 540ppm Proven
The star ingredient derived from Centella Asiatica. A powerful anti-inflammatory and antioxidant compound that promotes wound healing, reduces redness, and inhibits UV-induced melanin synthesis.
- Clinical Study: At 0.05%, used twice daily for 8 weeks, inhibited UV-induced melanin synthesis
- Wound Healing: Stimulates collagen synthesis and skin regeneration
- Anti-Inflammatory: Reduces redness and peeling in atopic dermatitis at 0.2%
โจ Niacinamide 2% (20,000ppm) Proven
A form of Vitamin B3 that brightens skin, regulates sebum production, minimizes pores, and strengthens the skin barrier. Works synergistically with Madecassoside.
- Brightening: Inhibits melanosome transfer to reduce hyperpigmentation
- Barrier Support: Increases ceramide and fatty acid production in skin
- Anti-Aging: Reduces fine lines and wrinkles with consistent use
๐ก๏ธ 4-TECA Complex 612ppm total Patented
A proprietary blend of four active compounds from Centella Asiatica: Madecassoside, Madecassic Acid, Asiaticoside, and Asiatic Acid for comprehensive skin barrier protection and repair.
- Asiaticoside (39ppm): Wound-healing and collagen synthesis
- Asiatic Acid: Stimulates collagen Type I synthesis
- Madecassic Acid: Anti-inflammatory and barrier repair
๐ง Panthenol Active Proven
Also known as Pro-Vitamin B5. A powerful humectant that deeply hydrates, soothes irritation, and supports skin barrier recovery. Excellent for sensitive and compromised skin.
- Hydration: Attracts and retains moisture in the skin
- Healing: Accelerates wound healing and tissue repair
- Anti-Inflammatory: Calms redness and irritation
40 ingredients
Water, Glycerin, Butylene Glycol, Propanediol, 1,2-Hexanediol, Niacinamide, Glyceryl Polymethacrylate, Panthenol, Betaine, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Diphenyl Dimethicone, Triethylhexanoin, Tromethamine, Madecassoside (540 ppm), Ethylhexylglycerin, Hydrogenated Lecithin, Xanthan Gum, Sodium Hyaluronate, Centella Asiatica Extract (51 ppm), Asiaticoside (39 ppm), Pyrus Communis (Pear) Fruit Extract, Juniperus Virginiana Oil, Centella Asiatica Leaf Extract (21 ppm), Beta-Glucan, Rosa Damascena Flower Water, Cucumis Melo (Melon) Fruit Extract, Iris Florentina Root Extract, Hedera Helix (Ivy) Leaf/Stem Extract, Simmondsia Chinensis (Jojoba) Seed Oil, Pogostemon Cablin Oil, Artemisia Vulgaris Oil, Rosmarinus Officinalis (Rosemary) Leaf Oil, Tocopherol, Dipropylene Glycol, Pentylene Glycol, Caprylyl/Capryl Glucoside, Madecassic Acid (0.00004 ppm), Asiatic Acid (0.00003 ppm), Ceramide NP
๐ Where It Fits in Your Routine
Apply after toner and before heavier treatments or moisturizer. Can be used both AM and PM.
๐ How to Use
Cleanse & Tone
Start with clean, freshly toned skin. Pat toner in and allow it to absorb before applying serum.
Dispense & Apply
Apply an adequate amount (2-3 pumps) to the entire face, focusing on areas with blemish marks or uneven tone.
Pat & Absorb
Gently pat the serum into skin to enhance absorption. Wait 30 seconds before applying the next step.
Follow Up
Continue with moisturizer and sunscreen (AM). For enhanced results, use with Mediheal Madecassoside sheet masks.
๐ค Who Is It For?
โ Perfect for you if:
- You have post-acne marks or hyperpigmentation
- Your skin is sensitive, irritated, or stressed
- You want to strengthen your skin barrier
- You have uneven skin tone or redness
- You're looking for a lightweight, non-greasy serum
- You're pregnant or breastfeeding (topical use)
โ Consider alternatives if:
- You have confirmed fungal acne (malassezia)
- You're allergic to Centella Asiatica or essential oils
- You need a heavy-duty anti-aging treatment
- You prefer fragrance-free products only
- You want a very high concentration of Vitamin C
๐ฏ Skin Type Compatibility
Lightweight, fast-absorbing formula won't add shine or greasiness. Non-comedogenic tested.
Provides hydration with hyaluronic acid and panthenol, but may need a richer moisturizer on top.
Balances well across different face zones without being too heavy or too light.
Hypoallergenic, dermatologically tested. Passed irritation test on sensitive skin. Soothes redness.
Non-comedogenic formula helps with post-acne marks. Caution if you have fungal acne.
๐ Results Timeline
Immediate Soothing
Skin feels calmer, less irritated. Redness from active breakouts begins to fade. Improved hydration levels.
85% noticed calming effectVisible Improvements
Clinical studies show: melanin levels improved by 16.3%, blemish marks soothed by 6.56%, skin barrier improved by 50.74%.
100% reported satisfactionNoticeable Brightening
Post-acne marks appear lighter. More even skin tone. Skin texture feels smoother and more refined.
78% noticed brighter skinLong-term Results
Significant reduction in hyperpigmentation. Strengthened skin barrier. Overall healthier, more resilient complexion.
90% would repurchaseโญ Ratings by Platform
โ๏ธ Pros & Cons
โ Praised
- Clinically proven to fade blemish marks
- Lightweight, non-greasy texture
- Soothes irritated and sensitive skin instantly
- German Dermatest excellent grade
- Non-comedogenic and hypoallergenic
- Fast-absorbing, layers well under makeup
- Good value vs. high-end alternatives
- Pregnancy safe for topical use
โ Criticized
- Small bottle size (40ml) for the price
- Contains essential oils (may irritate some)
- Not fungal acne safe
- Results take 2+ weeks to show
- Subtle herbal scent not for everyone
- Low concentration of individual actives
๐ฐ Budget-Friendly Alternatives (Dupes)
Minimal 7-ingredient formula with pure Centella Asiatica extract. More affordable and fungal acne safe, but lacks niacinamide for brightening. Best for pure soothing benefits.
Contains 85% Centella Asiatica Leaf Water. Smaller size (20ml) but more concentrated. Focuses on sebum control. No niacinamide but includes allantoin for soothing.
Different approach with Green Tea instead of Centella focus. Contains panthenol for soothing. Fungal acne safe. Good for calming but less targeted for blemish marks.
๐ Comparison with Competitors
Mediheal Madecassoside Serum (This Product)
$17-22 / 40mlSKIN1004 Madagascar Centella Ampoule
$14-18 / 55mlCOSRX Centella Blemish Ampule
$20-24 / 20mlSKIN1004 Tone Brightening Capsule Ampoule
$18-24 / 50ml๐ฆ Storage & Shelf Life
12 months after opening
Store in cool, dry place away from direct sunlight. Keep out of reach of children.
Pump bottle with protective cap for hygienic dispensing
Yes, 40ml is under 100ml TSA carry-on limit
โ Frequently Asked Questions
Yes, for topical use. This serum contains no retinoids, salicylic acid, hydroquinone, or other ingredients contraindicated during pregnancy. Centella Asiatica and Madecassoside are generally considered safe when applied topically during pregnancy and breastfeeding. However, always consult with your healthcare provider before adding new products to your routine during pregnancy.
Use with caution. This serum contains Polyglyceryl-10 Laurate and Jojoba Seed Oil (Simmondsia Chinensis), which may not be safe for fungal acne. If you're prone to fungal acne, consider alternatives like SKIN1004 Madagascar Centella Ampoule or COSRX Centella Blemish Ampule, which have cleaner formulas for malassezia-sensitive skin.
Yes! This serum is gentle and can be layered with most actives. Apply it after lighter textures (like vitamin C serums) and before heavier treatments (like retinol). When using with AHA/BHA, apply those first, wait a few minutes, then apply this serum. The soothing properties of Madecassoside actually help calm potential irritation from actives.
This serum works well for all skin types but excels for sensitive, irritated, and acne-prone skin. It's especially beneficial for those with post-acne marks, hyperpigmentation, or compromised skin barriers. The lightweight formula is ideal for oily and combination skin, while dry skin types may want to layer a richer moisturizer on top.
Soothing effects are immediate. Clinical studies show visible improvements in melanin levels and blemish marks after 2 weeks of consistent use. For significant fading of hyperpigmentation and post-acne marks, expect 4-8 weeks of regular application. Skin barrier improvements were shown at 50.74% after just 2 weeks in clinical testing.
Apply after cleansing and toning, before heavier serums and moisturizer. The order is: Cleanser โ Toner โ This Serum โ Other treatments (if any) โ Moisturizer โ Sunscreen (AM). It can be used both morning and night. The lightweight texture layers well and won't pill under makeup.
No, it has a comedogenic rating of 1/5. This serum is clinically tested and proven non-comedogenic. It passed German Dermatest with an "Excellent" grade and is specifically formulated for blemish-prone skin. The lightweight, fast-absorbing formula won't clog pores or contribute to breakouts.
The serum has a 12-month (12M) period after opening (PAO). Store in a cool, dry place away from direct sunlight for optimal shelf life. The pump packaging helps maintain hygiene and prevent contamination. With twice-daily use, the 40ml bottle typically lasts 6-8 weeks.
Verdict: The Mediheal Madecassoside Blemish Repair Serum is an excellent choice for those seeking a clinically-backed, gentle serum to fade post-blemish marks and calm irritated skin. With its 540ppm Madecassoside, 2% Niacinamide, and patented 4-TECA complex, it delivers measurable results in just 2 weeks. The lightweight, non-greasy formula suits most skin types and is safe during pregnancy. While not ideal for fungal acne and the bottle size is small for the price, the German Dermatest certification and comprehensive soothing benefits make it a solid investment for sensitive, blemish-prone skin. A worthy addition to any K-beauty routine focused on repair and brightening.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging ยซpromisesยป it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 1 |
Butylene Glycol
Solvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
|
Hydrating
|
|
| 1 |
Propanediol
Solvent, Viscosity Controlling, Viscosity Decreasing Agent
|
|
|
| 1 |
1,2-Hexanediol
Solvent, Skin Conditioning
|
Hydrating
|

