Maximum Strength 1% Hydrocortisone Anti-Itch Creme with Aloe
Maximum Strength 1% Hydrocortisone Anti-Itch Creme with Aloe
Product Description
Product overview
A fast-acting, maximum-strength 1% hydrocortisone anti-itch creme enriched with soothing aloe vera. Relieves itch from eczema, psoriasis, insect bites, poison ivy, rashes, and minor skin irritations in as little as 5 minutes with long-lasting relief that endures for hours. Fragrance-free, dye-free, and the #1 doctor-recommended OTC anti-itch brand.
Fast-Acting Itch Relief
Starts relieving itch in as little as 5 minutes with maximum-strength 1% hydrocortisone, the strongest available without a prescription.
Texture & feel
SENSORYFast-Acting Itch Relief
Starts relieving itch in as little as 5 minutes with maximum-strength 1% hydrocortisone, the strongest available without a prescription.
Soothing Aloe Vera
Enriched with aloe barbadensis leaf juice, providing vitamins, minerals, enzymes, and amino acids to moisturize and calm irritated skin.
Long-Lasting Relief
Provides itch relief that lasts for hours, so you can go about your day without constant reapplication.
Multi-Condition Coverage
Effective for eczema, psoriasis, poison ivy/oak/sumac, insect bites, seborrheic dermatitis, and irritation from detergents, jewelry, and cosmetics.
Safety & compatibility
SAFETopical hydrocortisone 1% is generally considered low-risk when used on small areas for short periods. However, the manufacturer recommends consulting your healthcare professional before use during pregnancy or breastfeeding. Avoid applying to breast area while nursing.
Not fungal acne safe. Contains beeswax (esters that can feed malassezia), mineral oil, and petrolatum. If you have fungal acne, consider a fungal-acne-safe alternative or consult a dermatologist.
Free from added fragrances and dyes, reducing the risk of additional irritation on already-compromised skin.
Do not use for more than 7 consecutive days unless directed by a doctor. Prolonged topical steroid use can cause skin thinning. Stop use if condition worsens or symptoms recur.
Cortizone-10 products are not tested on animals.
Do not use on children under 2 years of age without consulting a doctor. For ages 2 and up, apply as directed.
Formula includes methylparaben and propylparaben as preservatives. If you prefer paraben-free options, consider the Cortizone-10 Sensitive Skin variant.
Sodium lauryl sulfate is present as an emulsifier. This is a rinse-off-level concentration in a leave-on product, which may be irritating for some very sensitive skin types.
Ingredient breakdown
INGREDIENTSHydrocortisone 1%Proven
A mild topical corticosteroid that reduces inflammation, redness, swelling, and itching by suppressing the immune response in the skin. It is the maximum strength available over the counter in the United States.
- Mechanism: Activates glucocorticoid receptors in skin cells to reduce pro-inflammatory cytokines and histamine response
- Efficacy: Clinically proven to relieve itch from minor skin irritations, eczema, psoriasis, and contact dermatitis
- Onset: Relief begins within 5–10 minutes of application
Aloe Barbadensis Leaf JuiceProven
A natural botanical extract rich in vitamins A, C, E, minerals, enzymes, amino acids, and polysaccharides. Known for its skin-soothing, moisturizing, and wound-healing properties.
- Benefits: Provides cooling relief, helps moisturize and nourish irritated skin
- Research: Multiple studies support aloe vera's anti-inflammatory and wound-healing effects on skin
- Synergy: Complements hydrocortisone by soothing skin while the active ingredient reduces inflammation
GlycerinProven
A powerful humectant that attracts and retains moisture in the skin. One of the most studied and effective moisturizing ingredients available.
- Function: Draws water from the environment and deeper skin layers to hydrate the stratum corneum
- Research: A 2016 study found glycerin more effective as a humectant than hyaluronic acid and AHAs
Petrolatum & Mineral OilProven
Classic occlusive agents that form a protective barrier on the skin surface, preventing transepidermal water loss (TEWL) and locking in moisture.
- Petrolatum: Reduces TEWL by up to 98%, considered the gold standard of occlusives
- Mineral oil: Lightweight emollient that softens and smooths skin without clogging pores at cosmetic grades
16 ingredients
Active Ingredient: Hydrocortisone 1%
Inactive Ingredients: Aloe Barbadensis Leaf Juice, Aluminum Sulfate, Beeswax, Calcium Acetate, Cetearyl Alcohol, Dextrin, Glycerin, Maltodextrin, Methylparaben, Mineral Oil, Petrolatum, Propylparaben, Sodium Cetearyl Sulfate, Sodium Lauryl Sulfate, Water
Where it fits in your routine
ROUTINEApply only to affected areas, up to 3–4 times daily. Use as a targeted treatment — not an all-over cream. Can be used AM or PM as needed.
How to use
HOW TO USEClean the Affected Area
Gently wash the affected area with mild soap and warm water. Rinse thoroughly and pat dry with a soft cloth or towel.
Apply a Thin Layer
Squeeze a small amount of creme and apply a thin, even layer directly onto the itchy or irritated area. Do not rub vigorously — gentle application is best.
Allow to Absorb
Let the creme absorb into the skin for 1–2 minutes. Avoid covering with tight bandages or dressings unless directed by a doctor.
Repeat as Needed
Apply up to 3–4 times daily. Do not use for more than 7 consecutive days. If symptoms persist or worsen, discontinue use and consult a doctor.
Who is it for?
WHOPerfect for you if:
- You need fast relief from itching due to eczema, psoriasis, or dermatitis
- You've been bitten by insects (mosquitoes, ants, etc.) and need quick relief
- You have a rash from poison ivy, oak, or sumac
- Your skin is irritated from jewelry, cosmetics, detergents, or soaps
- You want a fragrance-free, dye-free anti-itch treatment
- You prefer a creme with soothing aloe vera rather than a plain steroid cream
- You need a compact, travel-friendly anti-itch solution
Consider alternatives if:
- You have a fungal skin infection (ringworm, athlete's foot) — hydrocortisone can worsen fungal conditions
- You need long-term itch relief (more than 7 days) — consult a doctor
- You have fungal acne (malassezia folliculitis) — this formula is not FA-safe
- You are very sensitive to parabens or SLS
- You need coverage for large body areas — this is a targeted spot treatment
- Your child is under 2 years old — consult a pediatrician first
Skin type compatibility
SKIN TYPESWorks effectively on normal skin. The aloe and emollient base soothe without leaving a heavy residue. Ideal for occasional itch from bites or rashes.
The petrolatum and mineral oil base provides excellent occlusion, locking in moisture on dry, itchy patches. Pair with a heavier moisturizer for full hydration.
Effective for itch relief but the petrolatum and mineral oil base may feel slightly heavy on oily areas. Best used as a targeted spot treatment only.
Fragrance-free and dye-free, but contains parabens and SLS which may irritate very reactive skin. Consider the Sensitive Skin variant if concerned.
Contains beeswax (comedogenic rating 2–4) and occlusives that may clog pores if applied to acne-prone areas. Use only on affected non-acne zones.
Results timeline
1–7 DAYS (WITH CONSISTENT USE)Immediate Itch Relief
Hydrocortisone begins blocking the inflammatory cascade, reducing the sensation of itching. Most users notice a significant decrease in the urge to scratch.
90% noticed reliefRedness & Swelling Reduction
Visible inflammation begins to calm. The aloe vera provides a cooling, soothing sensation and the emollient base locks in moisture to protect the irritated area.
80% noticed improvementSustained Comfort
Itch relief continues for hours after application. The occlusive barrier helps keep irritants out and moisture in while the skin begins to recover.
75% reported lasting reliefCondition Improvement
With regular application (3–4 times daily), minor rashes, insect bites, and contact dermatitis typically resolve. Eczema and psoriasis flares are managed. Discontinue use after 7 days or when symptoms clear.
85% reported resolution of minor irritationsRatings by platform
48K+ REVIEWSPros & cons
BALANCEDPraised
- Fast-acting itch relief — most users feel results within 5 minutes
- Maximum OTC strength at 1% hydrocortisone
- Soothing aloe vera adds extra skin comfort
- Fragrance-free and dye-free formula
- #1 doctor-recommended OTC anti-itch brand
- Versatile — works on insect bites, rashes, eczema, psoriasis, and more
- Compact and travel-friendly tube
- HSA/FSA eligible
- Cruelty-free — not tested on animals
Criticized
- Small tube size (1 oz) can run out quickly with frequent use
- Contains parabens (methylparaben, propylparaben) and SLS
- Not fungal acne safe due to beeswax and occlusive ingredients
- 7-day usage limit may not be enough for chronic conditions
- Petrolatum/mineral oil base can feel greasy on some skin types
- Not suitable for open wounds or infected skin without medical advice
- No safety seal on the tube
Budget-friendly alternatives (dupes)
DUPESSame 1% hydrocortisone active ingredient at a lower price point. Simpler formula without aloe vera. Basic but effective for straightforward itch relief on a budget.
Generic store-brand hydrocortisone 1% cream. Same active ingredient, very similar inactive base. Lacks the aloe vera formulation but delivers identical anti-itch potency at roughly half the price.
Features 1% hydrocortisone with colloidal oatmeal for additional soothing. Different moisturizing approach — oat-based rather than aloe-based. Great for those with dry, eczema-prone skin who want extra nourishment.
Comparison with competitors
SIDE-BY-SIDECortizone-10 Soothing Aloe Creme
Aquaphor Itch Relief Ointment 1%
CeraVe 1% Hydrocortisone Anti-Itch Cream
Storage & shelf life
12 MONTHS12 months after opening. Check expiration date on packaging. Do not use expired products.
Store in a cool, dry place out of direct sunlight. Keep out of reach of children.
Squeeze tube with screw cap. No safety seal — do not use if carton has been tampered with or product appears used.
Yes — 1 oz (28g) tube is well under the 3.4 oz / 100ml TSA carry-on limit. Compact and perfect for first aid kits, camping gear, and travel bags.
Frequently asked questions
FAQTopical hydrocortisone 1% is generally considered low-risk during pregnancy when applied to small areas for short periods. Very little is absorbed systemically through the skin. However, the manufacturer specifically advises consulting your healthcare professional before using during pregnancy or breastfeeding. If nursing, avoid applying to the breast area and wash hands after application. The NHS and MotherToBaby both indicate that short-term, small-area use of low-potency topical hydrocortisone is unlikely to pose a risk.
No, this product is not considered fungal acne safe. It contains beeswax (which has esters that can feed malassezia yeast), mineral oil, and petrolatum. While hydrocortisone itself can temporarily reduce inflammation associated with fungal acne, these inactive ingredients may worsen malassezia folliculitis over time. If you have fungal acne, consult a dermatologist for appropriate antifungal treatments instead.
It is generally best to avoid layering other active ingredients (retinol, vitamin C, AHA, BHA) directly on top of or under hydrocortisone on the same skin area, as these can increase irritation. Hydrocortisone is meant to calm inflammation, while acids and retinoids can cause irritation. If you use actives in your skincare routine, apply them to different areas of the face/body, or use them at different times (e.g., actives in the morning, hydrocortisone at night). When in doubt, consult your dermatologist.
This creme works well across most skin types. It is particularly well-suited for normal to dry skin due to its emollient base (petrolatum, mineral oil, beeswax, glycerin). The fragrance-free, dye-free formula makes it appropriate for sensitive skin, though those with very reactive skin may prefer the Cortizone-10 Sensitive Skin variant (paraben-free, hypoallergenic). Oily skin types can use it as a targeted spot treatment. It is not ideal for fungal-acne-prone skin.
Most users experience noticeable itch relief within 5–10 minutes of application. Visible reduction in redness and swelling typically occurs within 30 minutes to 1 hour. For minor skin irritations like insect bites or contact rashes, symptoms often resolve within 1–3 days of consistent use. For chronic conditions like eczema or psoriasis, you may see improvement within a few days, but do not use for more than 7 days without consulting a doctor.
This is a medicated treatment, not a daily skincare product. Apply it after cleansing and drying the affected area. If you also use moisturizer, apply the hydrocortisone creme first, wait about 10 minutes for it to absorb, then follow with your regular moisturizer on surrounding areas. Do not layer it under or over active serums (retinol, vitamin C, acids) on the same spot. Use it as needed up to 3–4 times daily.
The overall comedogenic rating is approximately 2 out of 5. Petrolatum and mineral oil are generally non-comedogenic at cosmetic grades, but beeswax has a comedogenic rating of 2–4 depending on the source. For most people using this as a targeted spot treatment on irritated areas, pore-clogging is unlikely. However, if you are highly acne-prone, avoid applying it to large areas of the face and stick to affected zones only.
The product has an approximate shelf life of 12 months after opening. Always check the expiration date printed on the tube and outer carton. The manufacturer advises not to use expired products. Store in a cool, dry place out of direct sunlight. There is no safety seal on the tube — do not use if the carton appears tampered with or the product looks used.
Verdict: Cortizone-10 Maximum Strength 1% Hydrocortisone Anti-Itch Creme with Aloe is a reliable, fast-acting, and well-established anti-itch treatment backed by decades of trust and the #1 doctor recommendation in its category. The combination of maximum-strength hydrocortisone with soothing aloe vera delivers effective itch relief within minutes for a wide range of skin irritations — from insect bites and poison ivy to eczema and psoriasis flares. The fragrance-free, dye-free formula is gentle enough for most skin types, and the compact tube is ideal for first aid kits and on-the-go use. The main drawbacks are the small 1 oz size, presence of parabens, and the fact that it is not suitable for fungal acne. For everyday itch emergencies, this is a medicine cabinet essential.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 0 |
Hydrocortisone
|
|
|
| 0 |
Aloe Barbadensis Leaf Juice
Skin Conditioning
|
Hydrating
Redness
Irritation
|
|
| 0 |
Aluminum Sulfate
Astringent
|
|
|
| 0 |
Beeswax
Emulsion Stabilising, Masking, Skin Conditioning
|
|
|
| 0 |
Calcium Acetate
Masking
|
|


