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MSM Face Mist

MSM Face Mist

Product Description

Product overview

Made in Various INTERNATIONAL

An ultra-fine antimicrobial face mist powered by Hexamidine Diisethionate and botanical extracts. Shields skin from bacteria, fungi, and environmental aggressors while calming irritation, reducing redness, and supporting skin barrier recovery. Lightweight, fast-absorbing, and suitable for all skin types including sensitive and acne-prone skin.

Fragrance-Free Alcohol-Free Paraben-Free Oil-Free Silicone-Free Fungal Acne Safe Non-Comedogenic Pregnancy Safe Sulfate-Free Antimicrobial
Pregnancy
Yes
Fungal Acne
Yes
Comedogenic
0/5
Size
50ml / 110ml
Type
Face Mist
Concern
Acne & Irritation
Skin Type
All Types
Ingredients
12
Real reviews · YouTube Shorts
Why it's different

Antimicrobial Shield

Hexamidine Diisethionate fights bacteria, fungi, and yeast on contact to prevent breakouts and maskne before they start.

01

Texture & feel

SENSORY
Consistency
Watery Mist
Scent
Fragrance-Free
Absorption
Instant
Finish
Natural / Dewy

Antimicrobial Shield

Hexamidine Diisethionate fights bacteria, fungi, and yeast on contact to prevent breakouts and maskne before they start.

Botanical Soothing Complex

Centella Asiatica, Chamomile, and Licorice Root work together to calm redness, irritation, and inflammation.

Lightweight Hydration

Glycerin and Pentylene Glycol deliver moisture without heaviness, leaving skin plump and refreshed.

Minimalist Formula

Only 12 clean ingredients. No fragrance, alcohol, oils, parabens, or silicones. Safe for sensitive and reactive skin.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding Safe

Contains no retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe during pregnancy and breastfeeding.

Fungal Acne (Malassezia) Safe

Free from ferments, fatty acids, esters, polysorbates, and oils. Hexamidine Diisethionate actively fights Malassezia fungi that cause fungal acne.

Non-Comedogenic (Rating: 0/5)

Completely oil-free and silicone-free formula. No pore-clogging ingredients detected. Safe for acne-prone skin.

Sensitive Skin Friendly

No fragrance, alcohol, or common allergens. Hexamidine Diisethionate is rated as very mild with excellent skin tolerability at concentrations up to 0.1%.

Compatible with Actives

Safe to use alongside retinol, vitamin C, AHA, BHA, and niacinamide. Works well as a soothing step before or after active ingredients.

Eye Area Caution

Some users report stinging if the mist gets into the eyes. Keep eyes closed during application as directed.

03

Ingredient breakdown

INGREDIENTS

Hexamidine Diisethionate ≤0.1%Proven

A broad-spectrum antimicrobial agent effective against bacteria, fungi, yeast, and molds. The star active in this formula, it targets acne-causing P. acnes and Malassezia fungi while also providing anti-inflammatory benefits and supporting skin barrier function.

  • Antimicrobial: Effective against Gram-positive and Gram-negative bacteria, fungi (including Malassezia), and yeasts at concentrations of 0.05–0.1%.
  • Anti-inflammatory: Inhibits lipase activity of P. acnes, indirectly reducing inflammation associated with acne.
  • Barrier Support: Studies show it increases corneocyte maturity and reduces transepidermal water loss (TEWL).
  • Safety: EU-approved preservative (max 0.1%). CIR Expert Panel deemed it safe at ≤0.1% concentration. Safe for all ages including infants.
Used since the 1950s in topical preparations. PubMed research confirms it plays a beneficial role in skin homeostasis.

Marrubium Vulgare Extract (White Horehound)Promising

A botanical extract from the White Horehound plant known for its anti-inflammatory, anti-irritant, and skin barrier-strengthening properties. Helps calm reactive and stressed skin.

  • Anti-inflammatory: Reduces redness and soothes irritated skin by inhibiting inflammatory mediators.
  • Barrier Repair: Strengthens the skin barrier against environmental stressors like pollution and UV damage.
  • Antioxidant: Contains polyphenolic compounds that protect against free radical damage.

Pentylene GlycolProven

A plant-derived (sugar beet) humectant that also serves as an antimicrobial booster. Draws moisture into the skin while enhancing the preservative efficacy of the formula.

  • Humectant: Low molecular weight allows deep hydration by drawing moisture from the environment into the skin.
  • Antimicrobial Booster: Enhances the antimicrobial activity of Hexamidine Diisethionate for a stronger protective effect.
  • Emollient: Softens and smooths the skin surface for a comfortable, non-sticky feel.

Centella Asiatica ExtractProven

A Southeast Asian herb rich in Madecassic Acid and Asiaticoside. Widely studied for wound healing, collagen synthesis, and anti-inflammatory effects. A cornerstone ingredient in K-beauty.

  • Wound Healing: Promotes collagen synthesis and supports faster healing of damaged skin, cuts, and flare-ups.
  • Anti-inflammatory: Rich in triterpenoid saponins that reduce redness and calm irritated skin.
  • Antioxidant: Contains Vitamin A, Vitamin C, B vitamins, and Asiatic Acid for comprehensive free radical protection.

Glycyrrhiza Glabra Root Extract (Licorice)Proven

A powerful brightening and anti-inflammatory botanical. Contains glabridin, which inhibits tyrosinase activity to reduce hyperpigmentation and dark spots.

  • Brightening: Glabridin has been shown to inhibit UVB-induced pigmentation. Some studies suggest it may be more effective than hydroquinone.
  • Anti-inflammatory: Glycyrrhizin and glycyrrhetinic acid reduce redness and calm dermatitis-prone skin.
  • Antioxidant: Protects skin from oxidative stress and environmental damage.

Anthemis Nobilis Flower Extract (Chamomile)Proven

Roman Chamomile extract, prized for centuries for its calming and soothing properties. Rich in bisabolol and flavonoids that reduce skin sensitivity and irritation.

  • Soothing: Calms redness, itching, and irritation in sensitive and reactive skin.
  • Antioxidant: Flavonoid compounds protect against environmental damage and premature aging.

12 ingredients

Water, Pentylene Glycol, Glycerin, Marrubium Vulgare Extract, Hexamidine Diisethionate, Anthemis Nobilis Flower Extract, Centella Asiatica Extract, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Polygonum Cuspidatum Root Extract, Rosmarinus Officinalis Leaf Extract, Scutellaria Baicalensis Root Extract

FREE FROM: Parabens, Fragrance, Alcohol, Oils, Silicones, Sulfates, Common Allergens, Essential Oils, Dyes, Mineral Oil, Formaldehyde, Phthalates, PEGs, Phenoxyethanol
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
MSM Face Mist
4
Serum
5
Moisturizer
6
Sunscreen

Use after toner and before serums. Can also be reapplied throughout the day over makeup, before wearing a mask, or after workouts. Versatile enough to be your last skincare step or a midday refresh.

05

How to use

HOW TO USE
1

Cleanse & Prep

Start with clean skin. Complete your cleansing and toning steps as usual.

2

Close Eyes & Spray

Hold the bottle approximately 20 cm away from your face. Close your eyes and spray evenly across the face in 3–5 pumps.

3

Let It Absorb

Allow the mist to settle and absorb naturally into the skin. No need to pat or rub — the ultra-fine particles absorb on their own.

4

Continue Routine or Reapply

Follow with serum and moisturizer, or reapply throughout the day as needed — before mask-wearing, after workouts, or as a makeup setting mist.

06

Who is it for?

WHO

Perfect for you if:

  • You struggle with acne, maskne, or bacterial/fungal breakouts
  • Your skin is sensitive, reactive, or prone to dermatitis or eczema
  • You want a lightweight, oil-free hydrating mist
  • You need a midday skin refresh that works over makeup
  • You prefer clean, minimalist formulas with few ingredients
  • You use tretinoin or other actives that cause irritation
  • You wear masks for extended periods and want to prevent maskne

Consider alternatives if:

  • You need intense, heavy-duty hydration for very dry skin
  • You want a mist with anti-aging peptides or strong actives
  • You prefer products with noticeable fragrance or sensorial experience
  • You are looking for a makeup setting spray with hold
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Completely oil-free and lightweight. Absorbs instantly without adding shine. Antimicrobial action helps control acne-causing bacteria on oily skin.

Dry Skin
Good

Provides lightweight hydration via Glycerin and Pentylene Glycol. Pair with a richer moisturizer on top for best results on dry skin.

Combination Skin
Excellent

Balances well across different face zones. Hydrates dry patches without overloading the oily T-zone. A fan-favorite among combination skin users.

Sensitive Skin
Excellent

Fragrance-free, alcohol-free, minimal formula. Chamomile and Centella actively calm irritation. Highly praised by users with dermatitis and eczema.

Acne-Prone Skin
Excellent

Non-comedogenic (0/5), fungal acne safe, and actively antimicrobial. Targets both bacterial and fungal acne. Zero oils or pore-clogging ingredients.

08

Results timeline

MONTH 2+
Day 1–3

Instant Soothing & Hydration

Skin feels immediately calmer, more hydrated, and refreshed after each application. Redness from irritation visibly reduced. Fine mist absorbs quickly with no sticky residue.

85% noticed instant soothing
Week 1–2

Reduced Breakouts & Maskne Control

Bacterial and fungal acne breakouts begin to subside. Skin under masks stays clearer. Irritation from tretinoin or other actives is noticeably calmer.

70% noticed fewer breakouts
Week 3–4

Clearer, Calmer Complexion

Consistent use shows a visibly calmer complexion with less redness. Dermatitis and eczema-prone areas appear more settled. Skin barrier feels stronger and more resilient.

65% reported clearer skin overall
Month 2+

Long-Term Skin Health

Ongoing use maintains antimicrobial protection and skin balance. Breakouts are less frequent and less severe. Skin stays healthier even under challenging conditions like mask-wearing.

60% saw sustained improvement
09

Ratings by platform

180+ REVIEWS
Female Daily
4.3
Rating
50+
Reviews
Main complaint: Some users report product oxidizes quickly; price considered high for Indonesian market
Brand Website
4.7
Rating
Popular
Best Seller
Main complaint: 50ml size runs out quickly with frequent use; wish larger size was more affordable
Shopee / Tokopedia
4.5
Rating
100+
Reviews
Main complaint: Can sting eyes if not careful during application; limited availability outside Indonesia
Picky (Go Picky)
4.4
Rating
30+
Reviews
Main complaint: Wish it came in a bigger bottle; not enough global distribution
10

Pros & cons

BALANCED

Praised

  • Effectively reduces acne, maskne, and fungal breakouts
  • Ultra-fine mist feels refreshing and absorbs instantly
  • Calms dermatitis, eczema, and tretinoin-induced irritation
  • Clean, minimalist 12-ingredient formula
  • Fragrance-free, oil-free, and pregnancy safe
  • Versatile — works as toner, mask prep, or midday refresh
  • Fungal acne safe with active antimicrobial ingredients
  • Great for soothing skin during purging phases

Criticized

  • 50ml bottle runs out quickly with frequent use
  • Some users report product can oxidize if stored improperly
  • Stings eyes — must keep eyes closed during application
  • Price is premium for the Indonesian market
  • Limited international availability
  • No strong sensorial experience (no scent or luxurious feel)
11

Budget-friendly alternatives (dupes)

DUPES
82% Match
SOS Daily Rescue Facial Spray
$28.00

Uses hypochlorous acid instead of Hexamidine Diisethionate for antimicrobial action. Only 3 ingredients (water, salt, HOCl). More widely available internationally but pricier. National Eczema Association approved.

65% Match
Antimicrobial Facial Cleanser for Acne
$12.99
Budget Pick

Also uses hypochlorous acid (HOCl) as its antimicrobial agent. Larger 8 oz bottle is much more affordable. FDA-cleared but designed more as a cleanser spray than a hydrating mist. Lacks botanical soothing extracts.

60% Match
Thermal Spring Water
$14.00
Similar

A thermal spring water mist that soothes and calms sensitive skin. Contains mineral-rich water but lacks active antimicrobial ingredients. Great for general soothing but does not target bacteria or fungi like MSM does.

12

Comparison with competitors

SIDE-BY-SIDE
SOS Daily Rescue Facial Spray
Key Active Hypochlorous Acid
Total Ingredients 3 (Ultra-minimal)
Botanical Extracts None
Fungal Acne Safe Yes
Size 120ml
Origin United States
Antimicrobial Eczema Therapy Clear Spray
Key Active Hypochlorous Acid
Total Ingredients 3 (Ultra-minimal)
Botanical Extracts None
Fungal Acne Safe Yes
Size 236ml (8 oz)
Origin United States
Thermal Spring Water
Key Active Thermal Spring Water
Total Ingredients 2 (Ultra-minimal)
Botanical Extracts None
Fungal Acne Safe Yes
Size 150ml
Origin France
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store in a cool, dry place away from direct sunlight to prevent oxidation. Refrigeration can extend freshness and enhance the cooling mist experience.

Packaging

Fine mist spray bottle with an ultra-fine nozzle for even distribution across the face.

Travel Friendly

Yes — 50ml size is under 100ml carry-on limit. Perfect for on-the-go use and air travel.

13

Frequently asked questions

FAQ

Yes. This product contains no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients flagged as unsafe during pregnancy or breastfeeding. All 12 ingredients — including Hexamidine Diisethionate, Glycerin, Pentylene Glycol, and the botanical extracts — are considered safe for use during pregnancy and nursing. However, as with any product, we recommend consulting your healthcare provider if you have specific concerns.

Yes. The formula is completely free from ferments, fatty acids (like oleic acid), esters, polysorbates, and oils — all of which can feed Malassezia yeast. Better yet, the active ingredient Hexamidine Diisethionate has demonstrated antimicrobial activity against Malassezia fungi, meaning it actively fights the organism that causes fungal acne rather than just avoiding it. This makes it an excellent choice for anyone dealing with fungal acne.

Yes. The MSM Face Mist is a gentle, soothing mist that is compatible with all active ingredients including retinol, retinoids (tretinoin), vitamin C (L-ascorbic acid), AHA (glycolic acid, lactic acid), and BHA (salicylic acid). Many users actually apply it during tretinoin use to calm irritation and redness caused by retinoid purging. Apply the mist before or after your actives — it will not interfere with their efficacy.

The MSM Face Mist is formulated for all skin types, but it especially excels for oily, combination, sensitive, and acne-prone skin. Its oil-free, lightweight texture absorbs instantly without adding shine, making it ideal for oily skin. The soothing botanical extracts (Centella, Chamomile, Licorice) make it a standout for sensitive and reactive skin types. Users with dry skin can use it for hydration but should layer a richer moisturizer on top.

Most users notice immediate soothing and hydration from the first application. For acne and breakout reduction, many users report visible improvement within 1–2 weeks of consistent use. Full benefits for skin barrier recovery and long-term breakout prevention are typically seen after 3–4 weeks of daily use (morning and evening). Results vary depending on your skin condition and how frequently you apply the product.

Apply the MSM Face Mist after cleansing and toning, but before serums and moisturizer (Step 3 in a typical routine). It can also be used as a final step after your entire routine, reapplied over makeup throughout the day, sprayed before wearing a mask to prevent maskne, or used after workouts as a refreshing skin reset. Its versatility is one of its biggest strengths.

No. The MSM Face Mist has a comedogenic rating of 0 out of 5, meaning it is completely non-comedogenic and will not clog pores. The formula is entirely free from oils, silicones, waxes, and fatty acids. None of the 12 ingredients are known to be pore-clogging. It is one of the safest face mists for acne-prone and congestion-prone skin.

The recommended Period After Opening (PAO) is 12 months. To maximize shelf life, store the bottle in a cool, dry place away from direct sunlight. Some users have reported that the product can oxidize if exposed to heat or light for extended periods, so proper storage is important. Refrigerating the product can help extend freshness and provides a cooling sensation when sprayed.

— Skincarisma verdict
4.3 / 5 ★★★★☆

Verdict: The Duvaderm MSM Face Mist is a standout antimicrobial face mist that goes far beyond basic hydration. Powered by Hexamidine Diisethionate and a clean botanical complex of Centella, Chamomile, and Licorice, it actively fights bacteria and fungi while soothing irritation — making it exceptional for acne-prone, sensitive, and reactive skin. Its minimalist 12-ingredient formula is pregnancy safe, fungal acne safe, and fully non-comedogenic (0/5). While the small bottle size and limited international availability are drawbacks, the efficacy-to-ingredient ratio is impressive. If you struggle with breakouts, maskne, dermatitis, or tretinoin irritation, this mist earns a strong recommendation as a daily skin shield.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 2 ingredient(s):
Centella Asiatica Extract Camellia Sinensis Leaf Extract
brightening Brightening from 1 ingredient(s):
Glycerin
wound Promotes Wound Healing from 2 ingredient(s):
Glycerin Centella Asiatica Extract
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
2
oily-skin Oily/Acne-Prone Skin
sensitive-skin Sensitive Skin
1
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
41% 58%

Product ingredient list

Showing first 5 of 12 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
1 A
Pentylene Glycol
Solvent, Skin Conditioning
2 A
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
brightening Brightening
Promotes Wound Healing
Hydrating
0 Unknown
Marrubium Vulgare Extract
Skin Conditioning, Soothing
0 Unknown
Hexamidine Diisethionate
Emollient, Preservative, Skin Conditioning
VIEW ALL INGREDIENTS