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Multi-Peptide Rich Cream

Multi-Peptide Rich Cream

Product Description

Product overview

Made in Various INTERNATIONAL

The Naturium Multi-Peptide Rich Cream is an ultra-rich, cushiony anti-aging moisturizer powered by a multi-peptide complex of Matrixyl (palmitoyl pentapeptide-4) and copper tripeptide-1, plus encapsulated ferulic acid and flaxseed extract. It visibly firms, smooths fine lines, and deeply nourishes dry and mature skin — fragrance-free, vegan, and under $30.

Naturium Brand Vegan Cruelty-Free Fragrance-Free Reef Safe Multi-Peptide Complex Dermatologist-Tested Under $30
Pregnancy
Likely
Fungal Acne
No
Comedogenic
2/5
Brand
Naturium
Size
50ml / 1.7oz
Type
Rich Moisturizer
Hero Actives
Multi-Peptide
Price
$25.00
Real reviews · YouTube Shorts
Why it's different

Triple Peptide Complex

Combines Matrixyl (palmitoyl pentapeptide-4), copper tripeptide-1 (GHK-Cu), and signal peptides to support collagen and visibly firm skin.

01

Texture & feel

SENSORY
Consistency
Rich, cushiony cream
Scent
Fragrance-Free
Absorption
Moderate (1–2 min)
Finish
Dewy & nourished

Triple Peptide Complex

Combines Matrixyl (palmitoyl pentapeptide-4), copper tripeptide-1 (GHK-Cu), and signal peptides to support collagen and visibly firm skin.

Deep, Lasting Hydration

Glycerin, sodium hyaluronate, mannitol, and flaxseed extract attract and lock in moisture for a plumped, comfortable feel that lasts.

Encapsulated Ferulic Acid

An encapsulated antioxidant delivery system protects against free radicals and helps target the look of fine lines and dullness.

Clean & Conscious

Vegan, cruelty-free, reef-safe, and fragrance-free, formulated without parabens, silicones, sulfates, or drying alcohols.

02

Safety & compatibility

SAFE
Retinoid-Free

Contains no retinoids, hydroquinone, or chemical sunscreen filters, making it a gentle anti-aging option.

Not Fungal-Acne Safe

Contains polyglyceryl esters, fatty esters, and other ingredients that can feed Malassezia yeast.

Fragrance-Free

No added parfum, a good fit for those who avoid fragranced moisturizers.

Layers With Actives

The brand confirms it can be layered over retinol or vitamin C thanks to its encapsulation technology.

Pregnancy: Ask Your OB

Peptide moisturizers are generally considered low-risk, but human data on topical copper peptides is limited.

Gentle For Most

Fragrance-free and free of harsh alcohols; a patch test is still recommended for very reactive skin.

03

Ingredient breakdown

INGREDIENTS

Copper Tripeptide-1 (GHK-Cu) ~0.15–0.25%Promising

A naturally occurring copper-bound peptide and one of the most studied carrier peptides in dermatology. It is valued for supporting collagen synthesis, skin firmness, and repair.

  • Mechanism: Acts as a carrier peptide that helps deliver copper and signals skin to remodel collagen.
  • Early evidence: A small 1998 study found increased procollagen in 7 of 10 users after one month.
Human studies remain small and mostly exploratory; results are promising rather than fully proven.

Palmitoyl Pentapeptide-4 (Matrixyl) ~0.15–0.30%Proven

A well-known signal peptide made of five amino acids. It encourages the skin to produce more collagen, supporting a firmer barrier and a smoother look of wrinkles over time.

  • Function: Signals fibroblasts to boost collagen, which helps soften the appearance of fine lines.
  • Best for: Anti-aging routines that aim for firmness without the irritation of retinoids.
One of the most widely used and best-tolerated anti-aging peptides in skincare.

Ferulic Acid (Encapsulated) EncapsulatedPromising

A plant-based antioxidant that helps neutralize free radicals linked to fine lines and uneven tone. Encapsulation helps keep it stable and supports a steady release into skin.

  • Antioxidant: Fights free-radical damage that can break down collagen.
  • Synergy: Classically used to stabilize and boost vitamin C and vitamin E.

Sodium Hyaluronate HumectantProven

The salt form of hyaluronic acid that holds water exceptionally well. It draws moisture into the upper layers of skin for an instantly plumped, hydrated feel.

  • Hydration: A naturally occurring humectant found in our own skin and joints.
  • Texture: Helps the cream feel cushiony without heaviness.

Glycerin High in formulaProven

A gold-standard humectant naturally found in skin. It pulls moisture into deeper layers, supporting a healthier barrier and relieving the tightness of dry skin.

  • Research: A 2016 study found glycerin more effective as a humectant than AHAs and hyaluronic acid.
  • Barrier: Hydrated skin is better protected against irritants and bacteria.

Vitamin E (Tocopherol) AntioxidantProven

A fat-soluble antioxidant that shields skin from free radicals and strengthens the lipid barrier. It pairs well with the formula's ferulic acid for added protection.

  • Barrier support: Helps keep natural skin lipids and ceramides healthy.
  • Absorption: Fat-soluble, so skin takes it up readily.

Asiaticoside (Centella Asiatica) SoothingPromising

An active compound from the popular soothing herb Centella asiatica. It supports wound healing and antioxidant activity, helping calm and restore the barrier.

  • Soothing: Linked to barrier restoration and reduced visible irritation.
  • Collagen: May support collagen production alongside other centella compounds.

Flaxseed (Linum Usitatissimum) Seed Extract PlumpingPromising

Linseed extract is included to help plump and lock in moisture, contributing to the cream's hydrated, healthy-looking finish on dry and mature skin.

  • Role: Supports moisture retention and a smoother, plumper surface.
Listed as a perfuming botanical; sensitive skin should patch test.

37 ingredients

Water, Caprylic/Capric Triglyceride, Glycerin, Octyldodecanol, Butylene Glycol, Polyglyceryl-3 Polyricinoleate, Cera Microcristallina, Magnesium Stearate, Polyglyceryl-3 Oleate, Undecane, 1,2-Hexanediol, Polyglyceryl-20 Octadecabehenate/Laurate, Sorbitan Olivate, Stearalkonium Bentonite, Magnesium Sulfate, Linum Usitatissimum (Flaxseed) Seed Extract, Sodium Hyaluronate, Mannitol, Phosphatidylcholine, Palmitoyl Pentapeptide-4, Copper Tripeptide-1, Ferulic Acid, Gold, Tocopherol, Tridecane, Asiaticoside, Propylene Carbonate, Glyceryl Caprylate, Cetyl Alcohol, Decyl Glucoside, P-Anisic Acid, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol.

FREE FROM: Added fragrance/parfum, Parabens, Silicones, Sulfates, Drying alcohols, Mineral oil, Essential oils, Common allergens — plus 100% Vegan & Cruelty-Free.
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Serum
4
Treatment
5
Rich Cream
6
SPF / PM Seal

Apply as one of your final steps to seal in actives. In the AM follow with sunscreen; at night it works as your last step. It layers beautifully over retinol or vitamin C thanks to its encapsulated delivery.

05

How to use

HOW TO USE
1

Cleanse & tone

Start with clean, slightly damp skin to help lock in extra hydration.

2

Apply treatments first

Layer any serums, retinol, or vitamin C before the cream so they reach skin directly.

3

Warm a dime-sized amount

The brand recommends a dime-sized dollop; a little goes a long way with this rich texture.

4

Press & smooth

Gently press and smooth over the face and neck, avoiding the immediate eye area.

5

Finish with SPF (AM)

In the morning, always follow with a broad-spectrum sunscreen to protect your results.

06

Who is it for?

WHO

Perfect for you if:

  • You have dry, dehydrated, or mature skin
  • You're targeting fine lines and loss of firmness
  • You want peptides without retinol irritation
  • You prefer fragrance-free, vegan formulas
  • You want an affordable anti-aging cream under $30

Consider alternatives if:

  • You have oily or very acne-prone skin
  • You're prone to fungal acne (Malassezia)
  • You prefer a lightweight gel texture
  • You want airless-pump packaging for hygiene
  • You want a single high-percentage active serum
07

Skin type compatibility

SKIN TYPES
Dry Skin
Excellent

Specifically reformulated to be richer than the original; deeply nourishing and barrier-supporting.

Mature / Aging
Excellent

Multi-peptide complex targets firmness and the look of fine lines without retinoid irritation.

Normal Skin
Excellent

Comfortable, cushiony hydration that layers well and sits nicely under makeup.

Combination
Good

Works well overall, though the oilier T-zone may prefer a lighter amount or the original formula.

Oily Skin
Moderate

Reviewers find the rich texture can feel heavy; the original Multi-Peptide Moisturizer may suit better.

Sensitive Skin
Good

Fragrance-free and free of harsh alcohols; patch test recommended due to perfuming botanicals.

08

Results timeline

WEEK 12+
Day 1 – Week 1

Immediate hydration & plumping

Skin feels cushioned and looks plumper right away as humectants and emollients restore moisture.

~85% noticed quick comfort
Week 2 – 4

Smoother, softer texture

Continued use leaves the surface noticeably softer and more refined, with a healthy-looking glow.

~78% reported smoother skin
Week 6 – 8

Firmer feel, softer lines

Peptides need time to work; this is when many users start to see firmer-looking skin and softened fine lines.

~64% saw firmer-looking skin
Week 12+

Cumulative anti-aging benefits

With consistent use, the collagen-supporting actives deliver their fullest visible firming and smoothing effects.

~70% would repurchase
09

Ratings by platform

434+ REVIEWS
Amazon
4.4
Rating
200+
Reviews (approx.)
Main complaint: Too rich and heavy for oily or warm-weather use
Target
3.8
Rating
154
Reviews
Main complaint: Some find the texture thick or experience slight pilling
Ulta
4.3
Rating
80+
Reviews (approx.)
Main complaint: 50ml tube feels small relative to the price
Naturium & Editorial
4.6
Rating
Cult favorite
Reputation
Main complaint: Editors note it can be excessive for oilier skin types
10

Pros & cons

BALANCED

Praised

  • Rich, long-lasting hydration that resists evaporating
  • Visibly plumps and helps firm the skin
  • Multiple well-studied peptides in one cream
  • Fragrance-free, vegan, and cruelty-free
  • Affordable for the level of actives ($25)
  • Layers nicely under makeup and SPF

Criticized

  • Too heavy for oily or acne-prone skin
  • Not fungal-acne (Malassezia) safe
  • Tube packaging is not airless
  • 50ml size feels small to some buyers
  • Peptide results take several weeks of use
11

Budget-friendly alternatives (dupes)

DUPES
75% Match
Peptide Moisturizer
$15.99
Budget Pick

A lighter daily peptide moisturizer with signal peptides. Less rich and without copper tripeptide, but a great low-cost entry point for peptide skincare.

65% Match
Multi-Peptide + HA Serum
$17.90
Budget Pick

A peptide serum rather than a cream. Delivers a multi-peptide hit at low cost but needs a moisturizer on top, especially for dry skin.

60% Match
Regenerist Micro-Sculpting Cream Face Moisturizer
$28.99
Similar Pick

A drugstore peptide cream with palmitoyl pentapeptide and niacinamide. Often contains fragrance, but a proven, widely loved firming workhorse.

12

Comparison with competitors

SIDE-BY-SIDE
Peptide Moisturizer
Key Peptides Signal peptides
Size 50ml
Texture Lightweight cream
Fragrance Fragrance-free
Best For Budget / normal skin
Regenerist Micro-Sculpting Cream Face Moisturizer
Key Peptides Pentapeptide + Niacinamide
Size 48g
Texture Rich cream
Fragrance Often fragranced
Best For Mature skin
1% Retinol Booster
Key Peptides Multi-peptide blend
Size 20ml
Texture Lightweight serum
Fragrance Fragrance-free
Best For Oily skin / layering
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store in a cool, dry place away from direct sunlight; close the cap firmly after each use.

Packaging

Squeeze tube, 50ml / 1.7 fl oz

Travel Friendly

Yes — 50ml is well under the 100ml carry-on limit

13

Frequently asked questions

FAQ

The formula contains no retinoids, hydroquinone, high-dose salicylic acid, or chemical sunscreen filters, which are the actives most often avoided during pregnancy. Peptide moisturizers are generally considered low-risk, but human safety data on topical copper peptides specifically is limited, so we rate it "Likely" rather than confirmed. Always check with your OB-GYN or midwife before adding any product during pregnancy or breastfeeding.

No. The cream contains several ingredients that can feed Malassezia yeast, including polyglyceryl esters (such as polyglyceryl-3 polyricinoleate and polyglyceryl-3 oleate), sorbitan olivate, and glyceryl caprylate. If you are prone to fungal acne, this is not the best choice — look for a fungal-acne-safe moisturizer instead.

Yes. Naturium states the cream can be layered with retinol or vitamin C thanks to its encapsulated delivery system. Apply your active treatment first, then seal it in with the cream. Layering over retinol can further support the look of fine lines, while vitamin C adds antioxidant protection. With strong AHA/BHA exfoliants, alternate or space them out if you notice any sensitivity, and always wear SPF.

It is compatible with most skin types but is especially designed for dry, dehydrated, and mature skin. The richer, creamier texture provides extra barrier support compared with the original Multi-Peptide Moisturizer. Oily and acne-prone skin may find it too heavy and could prefer the lighter original version.

Hydration and a plumper, more comfortable feel are usually immediate. Smoother texture tends to appear within 2–4 weeks. Because peptides support collagen gradually, firmer-looking skin and softened fine lines typically become more noticeable around 6–12 weeks of consistent daily use.

It is a moisturizer, so it goes near the end of your routine after cleansing, toning, and any serums or treatments. In the morning, follow it with sunscreen; at night it can be your final step. A dime-sized amount pressed and smoothed over the face and neck is all you need.

We rate it around 2 out of 5. It is formulated without heavy comedogenic oils and is oil-free, but the rich emollient base can feel heavy on very oily or congestion-prone skin. Most normal, dry, and combination skin tolerate it well; oily skin may prefer a lighter texture.

The Period After Opening (PAO) is approximately 12 months. Store it in a cool, dry place away from direct sunlight and close the tube firmly after each use to keep the actives stable and effective.

— Skincarisma verdict
4.3 / 5 ★★★★☆

Verdict: Naturium's Multi-Peptide Rich Cream is a standout affordable anti-aging moisturizer for dry and mature skin. It pairs two of the most respected peptides — Matrixyl and copper tripeptide-1 — with encapsulated ferulic acid, hyaluronic acid, and flaxseed extract for rich, long-lasting hydration and gradual firming, all fragrance-free, vegan, and under $30. The main trade-offs are that the cushiony texture can feel heavy on oily skin, the formula is not fungal-acne safe, and the tube packaging isn't airless. For anyone wanting visible peptide benefits without retinoid irritation, it's an easy recommendation.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 4 ingredient(s):
Palmitoyl Pentapeptide-4 Copper Tripeptide-1 Ferulic Acid Tocopherol
brightening Brightening from 1 ingredient(s):
Glycerin
wound Promotes Wound Healing from 5 ingredient(s):
Glycerin Sodium Hyaluronate Copper Tripeptide-1 Tocopherol Asiaticoside
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
4
oily-skin Oily/Acne-Prone Skin
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
59% 8% 32%

Product ingredient list

Showing first 5 of 37 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
1 A
Caprylic/Capric Triglyceride
Solvent, Skin Conditioning, Masking, Perfuming, Emollient
2 A
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
brightening Brightening
Promotes Wound Healing
Hydrating
1 A
Octyldodecanol
Solvent, Skin Conditioning, Perfuming, Emollient, Fragrance
1 A
Butylene Glycol
Solvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
Hydrating
VIEW ALL INGREDIENTS