Niacinamide Serum
Niacinamide Serum
Product Description
Product overview
A lightweight, fast-absorbing 10% niacinamide serum enriched with a gentle AHA blend to visibly minimize pores, balance oil production, and brighten uneven skin tone. This German drugstore gem delivers clinical-strength results at an affordable price.
Pore-Minimizing Power
10% niacinamide visibly tightens enlarged pores and regulates excess sebum production for a refined, smoother complexion.
Texture & feel
SENSORYPore-Minimizing Power
10% niacinamide visibly tightens enlarged pores and regulates excess sebum production for a refined, smoother complexion.
Brightening AHA Blend
Gentle multi-acid complex (citric, malic, fumaric acids) promotes cell turnover for a more even, radiant skin tone.
Deep Hydration
Glycerin and methylpropanediol attract and lock in moisture without heaviness or greasiness.
Barrier Support
Niacinamide strengthens the skin barrier by boosting ceramide production for healthier, more resilient skin.
Safety & compatibility
SAFEManufacturer advises caution. While niacinamide is safe, this formula contains AHAs and sodium salicylate. Consult your healthcare provider before use.
No oils, fatty acids, esters, ferments, or polysorbates. Niacinamide may actually help inhibit yeast overgrowth.
Water-based formula with 0/5 comedogenic rating. No pore-clogging ingredients detected.
High-concentration niacinamide (10%) may cause initial tingling in sensitive individuals. Start every other day.
Ingredient breakdown
INGREDIENTSNiacinamide (Vitamin B3) 10%Proven
A multi-tasking powerhouse that addresses enlarged pores, uneven skin tone, fine lines, and excess oil production. Strengthens the skin barrier by increasing ceramide synthesis.
- Clinical evidence: 4-5% concentration shown effective for sebum regulation and anti-aging in peer-reviewed studies
- Mechanism: Inhibits melanosome transfer to reduce hyperpigmentation
- Compatibility: Works well with most ingredients except pure vitamin C (use at different times)
AHA Blend (Citric, Malic, Fumaric, Maleic Acids) Low %Proven
A gentle multi-acid complex that provides mild exfoliation to promote cell turnover, improve texture, and enhance skin brightness without the harshness of high-concentration AHAs.
- Citric Acid: Derived from citrus, helps brighten and even skin tone
- Malic Acid: From apples, hydrates while exfoliating
- Function: Also serves as pH adjusters to optimize formula stability
Glycerin ~5%Proven
A naturally-occurring humectant that attracts moisture from the environment and deeper skin layers to keep the surface hydrated and plump.
- Research: 2016 study found glycerin more effective than hyaluronic acid as a humectant
- Benefits: Improves skin barrier function and maintains moisture balance
- Safety: 0 comedogenicity rating, suitable for all skin types
14 ingredients
Aqua, Niacinamide, Methylpropanediol, Glycerin, Propylene Glycol, Xanthan Gum, Aspartic Acid, Sodium Salicylate, Citric Acid, Sodium Hydroxide, Tetrasodium Iminodisuccinate, Fumaric Acid, Maleic Acid, Malic Acid
Where it fits in your routine
ROUTINEApply after water-based products (toner/essence) and before heavier creams. Can be used AM and PM. Always follow with SPF 30+ in the morning.
How to use
HOW TO USECleanse & Prep
Start with clean, slightly damp skin. Apply any toner or essence first.
Apply 2-3 Drops
Dispense onto fingertips and gently pat onto face, neck, and décolleté. Avoid direct eye contact.
Allow Absorption
Wait 30 seconds for the serum to fully absorb before layering additional products.
Follow with Moisturizer
Seal with your favorite moisturizer. In the morning, finish with SPF 30 or higher.
Who is it for?
WHOPerfect for you if:
- You have enlarged pores or visible blackheads
- Your skin is oily or produces excess sebum
- You want to address uneven skin tone or dullness
- You're looking for a budget-friendly niacinamide serum
- You have fungal acne and need a safe formula
- You prefer fragrance-free, minimal ingredient products
Consider alternatives if:
- You are pregnant or breastfeeding (consult doctor first)
- You have extremely dry skin that needs rich, occlusive formulas
- You're sensitive to high-concentration niacinamide (10%)
- You prefer products with added zinc for acne
- You want a serum with anti-aging peptides or retinol
Skin type compatibility
SKIN TYPESIdeal match. Regulates sebum, minimizes shine, and mattifies without over-drying. Lightweight texture absorbs instantly.
Balances T-zone oiliness while providing gentle hydration to drier areas. Won't exacerbate either condition.
Non-comedogenic, fungal acne safe. Niacinamide reduces inflammation and helps prevent future breakouts.
Great for maintaining healthy skin and preventing signs of aging. Provides gentle brightening benefits.
Hydrating but lightweight. Pair with a richer moisturizer or add hyaluronic acid serum for additional hydration.
Fragrance-free formula is gentle. Start slowly (every other day) as 10% niacinamide may cause initial tingling.
Results timeline
WEEK 12+Immediate Hydration & Smoother Feel
Skin feels more hydrated and supple. Surface texture may feel smoother. Some users notice reduced shine in the T-zone.
70% noticed improvementVisible Pore Refinement
Enlarged pores begin to appear smaller. Oil production becomes more balanced. Early signs of improved skin tone.
65% noticed improvementBrighter, More Even Complexion
Noticeable improvement in skin radiance and evenness. Dark spots and post-acne marks begin to fade. Skin barrier feels stronger.
80% noticed improvementMaximum Results
Significant reduction in hyperpigmentation and visible pore size. Skin appears healthier, smoother, and more resilient with consistent use.
85% noticed improvementRatings by platform
112+ REVIEWSPros & cons
BALANCEDPraised
- Excellent value for clinical-strength 10% niacinamide
- Clean, minimal ingredient list (only 14 ingredients)
- Fragrance-free and fungal acne safe
- Lightweight, fast-absorbing texture
- Visibly reduces pore appearance with consistent use
- Free from parabens, silicones, and common irritants
- Microplastic-free commitment from ISANA brand
Criticized
- Limited availability outside Germany/Europe
- No added zinc for acne (unlike The Ordinary)
- Pregnancy caution due to AHA content
- Small 30ml bottle size
- Can feel slightly sticky before fully absorbing
- No dropper included (squeeze tube design)
Budget-friendly alternatives (dupes)
DUPESNearly identical niacinamide concentration with added zinc PCA for enhanced oil control. More widely available globally. Slightly stickier texture.
Higher niacinamide concentration (12%) with zinc. Clean formula with no fragrance. More elegant texture that layers well under makeup.
10% niacinamide in a simpler base formula. Very affordable and easily accessible. Lacks the AHA blend but extremely gentle for sensitive skin.
Comparison with competitors
SIDE-BY-SIDEStorage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight. No refrigeration required.
Opaque plastic squeeze tube with flip-top cap. Protects active ingredients from light degradation.
Yes, 30ml is under 100ml TSA/airport liquid limit. Compact size fits easily in carry-on.
Frequently asked questions
FAQThe manufacturer advises that this product is not suitable for pregnant and lactating women. While niacinamide itself is generally considered safe during pregnancy, this formula contains AHAs (citric, malic, fumaric acids) and sodium salicylate which may warrant caution. We recommend consulting with your healthcare provider or dermatologist before use during pregnancy or breastfeeding.
Yes! This serum is 100% fungal acne safe. It contains no oils, fatty acids, esters, ferments, or polysorbates that feed malassezia yeast. The water-based formula with niacinamide may actually help inhibit yeast overgrowth due to its antimicrobial properties. It's an excellent choice for those with pityrosporum folliculitis.
With retinol: Yes, niacinamide pairs excellently with retinol and may reduce retinol-induced irritation. With vitamin C: Use at different times (vitamin C in AM, niacinamide in PM) as they may reduce each other's effectiveness when combined. With AHA/BHA: Yes, but since this serum already contains mild AHAs, be cautious about over-exfoliation. Start slowly and monitor your skin.
This serum is best suited for oily, combination, and acne-prone skin types. The 10% niacinamide effectively regulates sebum and minimizes pores. It also works well for normal skin seeking brightening benefits. Those with very dry skin may find it too lightweight and should pair it with a richer moisturizer.
Most users notice improved hydration and smoother texture within 1-2 weeks. Visible pore refinement typically occurs at 3-4 weeks. For significant improvements in skin tone, dark spots, and overall radiance, expect 6-12 weeks of consistent twice-daily use. Maximum results are typically seen at 12+ weeks.
Apply after cleansing and toning, but before heavier serums, moisturizers, and oils. The general rule is thinnest to thickest consistency. Use 2-3 drops morning and evening. In your AM routine, always follow with SPF 30+ as the last step. Wait 30 seconds between layers for optimal absorption.
No, this serum has a comedogenic rating of 0/5. It's a water-based formula containing no oils, silicones, or known pore-clogging ingredients. In fact, niacinamide actively helps minimize the appearance of pores and regulate oil production, making it ideal for those prone to blackheads and congestion.
The PAO (Period After Opening) is 12 months. The opaque packaging helps protect the active ingredients from light degradation. Store in a cool, dry place away from direct sunlight for maximum shelf life. If you notice any changes in color, smell, or texture, discontinue use.
Verdict: ISANA Niacinamide Serum is an impressive German drugstore find that delivers clinical-strength 10% niacinamide at a remarkably affordable price. The clean, 14-ingredient formula is fungal acne safe, fragrance-free, and includes a gentle AHA blend for enhanced brightening. While availability outside Europe is limited and pregnant users should exercise caution, this is an excellent choice for those with oily, combination, or acne-prone skin seeking pore refinement and improved skin tone. A fantastic budget alternative to premium niacinamide serums.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 1 |
Niacinamide
Skin Conditioning, Hair Conditioning, Smoothing
|
Promotes Wound Healing
Redness
Irritation
Dark Spots
Pores
|
|
| 1 |
Methylpropanediol
Solvent
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 3 |
Propylene Glycol
Solvent, Skin Conditioning, Fragrance, Humectant, Viscosity Controlling, Viscosity Decreasing Agent, Skin-Conditioningagent - Miscellaneous
|
Hydrating
|






