Overnight Moisture Serum
Overnight Moisture Serum
Product Description
Product overview
A lightweight overnight serum featuring 5% Niacinamide (Vitamin B3) and 5% Glycerin with Aquaxyl technology to deliver deep, long-lasting hydration that builds a moisture depot lasting up to 148 hours. Promotes skin renewal, strengthens the moisture barrier, and helps achieve a more even, radiant complexion while you sleep.
148-Hour Moisture Depot
Aquaxyl technology builds a long-lasting hydration reservoir that continues to moisturize skin for up to 148 hours after 21 days of consistent use.
Texture & feel
SENSORY148-Hour Moisture Depot
Aquaxyl technology builds a long-lasting hydration reservoir that continues to moisturize skin for up to 148 hours after 21 days of consistent use.
Skin Renewal Support
5% Niacinamide accelerates cell turnover and improves skin barrier function, helping to prevent visible signs of aging and uneven texture.
Even Skin Tone
Niacinamide combined with grape extract helps reduce hyperpigmentation and promotes a more uniform, radiant complexion over time.
Barrier Strengthening
The glycerin-rich formula supports the skin's natural moisture barrier, reducing transepidermal water loss and protecting against environmental stressors.
Safety & compatibility
SAFEContains only pregnancy-safe ingredients. Niacinamide (Vitamin B3) and glycerin are FDA-approved for use during pregnancy and nursing.
Free from oils, fatty acids, and esters that feed Malassezia yeast. Contains no problematic C11-C24 carbon chain ingredients.
Comedogenic rating of 0/5. Contains no pore-clogging ingredients. Safe for acne-prone skin.
Fragrance-free, alcohol-free, and dermatologically tested. Gentle enough for reactive and sensitive skin types.
Contains a low concentration of lactic acid for gentle exfoliation. Use sunscreen during the day as AHAs can increase sun sensitivity.
As with any new skincare product, perform a patch test on a small area before full application, especially if you have very reactive skin.
Ingredient breakdown
INGREDIENTSNiacinamide (Vitamin B3) 5%Proven
A multi-functional skincare powerhouse that addresses multiple skin concerns simultaneously. At 5% concentration, it delivers optimal benefits without irritation risk.
- Clinical Evidence: Studies show 4-5% niacinamide effectively reduces sebum production, minimizes pores, and improves skin barrier function.
- Brightening: Inhibits melanosome transfer to reduce hyperpigmentation and even out skin tone.
- Anti-Aging: Stimulates collagen synthesis and reduces fine lines and wrinkles.
Glycerin 5%Proven
One of the most effective and well-researched humectants in skincare. Naturally present in skin, it draws moisture from deeper layers and the environment to hydrate the stratum corneum.
- Research: A 2016 study found glycerin more effective as a humectant than hyaluronic acid and AHAs.
- Barrier Support: Helps maintain the skin's lipid barrier in a healthy liquid crystal state.
- Antimicrobial: Exhibits antimicrobial and antiviral properties that support skin health.
Aquaxyl Complex 3-5%Proven
A patented hydration complex consisting of Xylitylglucoside, Anhydroxylitol, and Xylitol. Provides 3D hydration by targeting multiple skin layers.
- Moisture Depot: Builds a hydration reservoir lasting up to 148 hours after 21 days of use.
- Comparative Study: Journal of Cosmetic Dermatology found 4% Aquaxyl performed as well as urea for hydration.
- Barrier Protection: Reinforces the outer layer of skin to prevent moisture loss.
Vitis Vinifera (Grape) Fruit Extract <1%Promising
Rich in antioxidants including Vitamin E, Vitamin C, proanthocyanidins, polyphenols, and flavonoids. Provides protection against oxidative stress.
- Antioxidant Power: Neutralizes free radicals that contribute to premature aging.
- Skin Tone: Proanthocyanidins help even out skin tone and reduce discoloration.
Lactic Acid <1%Proven
A gentle alpha-hydroxy acid (AHA) that provides mild exfoliation while supporting skin hydration. At low concentrations, it works more as a humectant than an exfoliant.
- Gentle Exfoliation: Promotes cell turnover without irritation at low concentrations.
- Microbiome Support: Studies show lactic acid can support beneficial skin bacteria.
- Hydration: Acts as a humectant, drawing moisture into the skin.
13 ingredients
Aqua, Glycerin, Niacinamide, Phenoxyethanol, Xylitylglucoside, Xanthan Gum, Hydroxyacetophenone, Anhydroxylitol, Microcrystalline Cellulose, Xylitol, Lactic Acid, Glucose, Vitis Vinifera Fruit Extract
Where it fits in your routine
ROUTINEApply in the evening after cleansing. Can be used as a standalone treatment or followed by a heavier moisturizer for dry skin types. No additional night care needed for most skin types.
How to use
HOW TO USECleanse Your Face
Start with clean, dry skin. Use your preferred gentle cleanser to remove makeup, sunscreen, and impurities from the day.
Apply 2-3 Drops
Dispense 2-3 drops of serum onto your fingertips or directly onto your face, focusing on areas that need extra hydration.
Gently Massage
Apply to face, neck, and décolleté using gentle pressing motions. Avoid the immediate eye area.
Allow to Absorb
Wait 30-60 seconds for full absorption. The serum can be used as a standalone overnight treatment—no additional moisturizer required for most skin types.
Who is it for?
WHOPerfect for you if:
- You want a simple, effective overnight hydration treatment
- You have dehydrated or dry skin that needs a moisture boost
- You're looking for a pregnancy or breastfeeding-safe serum
- You have fungal acne and need malassezia-safe products
- You prefer fragrance-free, minimal ingredient formulas
- You want to address uneven skin tone and texture
- You're on a budget but want effective skincare
- You have sensitive or reactive skin
Consider alternatives if:
- You need intensive anti-aging with retinoids (this doesn't contain retinol)
- You prefer products with added fragrance
- You want a richer, more occlusive formula for very dry skin
- You're looking for high-concentration active treatment serums
- You need a product with SPF (this is for PM use only)
Skin type compatibility
SKIN TYPESLightweight gel formula absorbs quickly without adding shine. Niacinamide helps regulate sebum production and minimize enlarged pores.
Provides excellent hydration with Aquaxyl technology. Very dry skin may benefit from layering a heavier moisturizer on top.
Balances well across different face zones. Hydrates dry areas while controlling oil in the T-zone without heaviness.
Fragrance-free and minimal ingredient formula. Niacinamide helps calm redness and strengthen skin barrier. Dermatologically tested.
Non-comedogenic formula with 0/5 rating. Fungal acne safe. Niacinamide helps reduce blemishes and regulate oil production.
Results timeline
WEEK 8+Immediate Hydration Boost
Skin feels more hydrated and plump. The Aquaxyl complex begins building moisture reserves. Surface dryness and tightness visibly reduced.
85% noticed improvementImproved Texture & Tone
Skin texture becomes smoother as niacinamide promotes cell turnover. Pores appear minimized and skin tone begins to look more even.
72% noticed improvementVisible Brightening
Hyperpigmentation and dark spots start to fade. Skin barrier is noticeably stronger. Overall complexion appears more radiant and healthy.
65% noticed improvementLong-Term Benefits
Continued use maintains hydration levels and prevents dryness. Sustained 148-hour moisture depot effect. Skin renewal cycle fully supported.
78% continued useRatings by platform
200+ REVIEWSPros & cons
BALANCEDPraised
- Exceptional value for money (€3.99 for 30ml)
- Clean, minimal 13-ingredient formula
- Pregnancy and breastfeeding safe
- Fungal acne (malassezia) safe
- Lightweight, fast-absorbing texture
- No fragrance or essential oils
- Clinically-proven Aquaxyl technology
- Suitable for sensitive and reactive skin
- Can be used as standalone night treatment
- German quality from trusted Rossmann brand
Criticized
- Limited availability outside Germany/Europe
- Small 30ml bottle size
- May not be hydrating enough for very dry skin alone
- No active anti-aging ingredients like retinol
- Can feel slightly sticky if over-applied
- Often sells out in stores
- Plain, basic packaging
Budget-friendly alternatives (dupes)
DUPES
Higher niacinamide concentration (10% vs 5%). More targeted for oil control. Lacks Aquaxyl hydration technology. May cause irritation in sensitive skin due to higher concentration.
Contains niacinamide and hyaluronic acid. Richer lotion texture with ceramides. More moisturizing but not fungal acne safe due to fatty acids. Better for dry skin types.
Higher niacinamide concentration with added vitamin C and licorice extract. More luxurious formula but significantly more expensive. Better for hyperpigmentation concerns.
Similar niacinamide concentration with added zinc. Very affordable option. Simpler formula without Aquaxyl technology. Good alternative for oily and acne-prone skin.
Comparison with competitors
SIDE-BY-SIDE
Storage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight. Room temperature is ideal (15-25°C).
Plastic dropper bottle with twist cap for hygienic dispensing
Yes, 30ml is under 100ml TSA/EU carry-on limit
Frequently asked questions
FAQYes, this serum is considered safe for use during pregnancy and breastfeeding. It contains only pregnancy-safe ingredients including niacinamide (Vitamin B3), glycerin, and the Aquaxyl hydration complex. There are no retinoids, salicylic acid, hydroquinone, or chemical sunscreens in the formula. The low concentration of lactic acid is within safe limits for topical use. However, as with any skincare product, we recommend consulting with your healthcare provider before starting new products during pregnancy.
Yes, this serum is fungal acne safe. The formula contains no oils, fatty acids, esters, or fermented ingredients that feed Malassezia yeast. Key ingredients like glycerin, niacinamide, and the sugar-based Aquaxyl complex are all confirmed safe for malassezia-prone skin. The product has been verified through ingredient analysis databases and does not contain problematic C11-C24 carbon chain ingredients.
Yes, niacinamide is compatible with most other active ingredients. You can use this serum with retinol (apply retinol first, then this serum), vitamin C (can be used in the same routine), and AHAs/BHAs (the low lactic acid content won't cause issues). For sensitive skin, consider alternating nights if using multiple active treatments. The serum's hydrating properties can help buffer potential irritation from stronger actives like retinol.
This serum works well for all skin types but is particularly excellent for oily, combination, sensitive, and acne-prone skin. The lightweight gel texture won't clog pores or add excess oil. For very dry skin, it provides good hydration but may benefit from a heavier moisturizer layered on top. The niacinamide helps regulate sebum production for oily skin while the Aquaxyl complex provides long-lasting hydration for dehydrated skin.
Most users notice improved hydration and skin texture within 1-2 weeks. For more significant improvements in skin tone, pore appearance, and barrier function, expect to see results after 4-8 weeks of consistent nightly use. The Aquaxyl complex builds a moisture depot over 21 days that provides hydration lasting up to 148 hours. For hyperpigmentation and uneven skin tone, continued use over 2-3 months provides the best results.
Apply this serum in the evening after cleansing (and toning, if you use one). It should be applied before heavier treatments, moisturizers, or sleeping masks. The formula is lightweight enough to serve as a standalone overnight treatment for normal to oily skin. If using retinol, apply retinol first, wait a few minutes, then apply this serum. In the morning, always follow with sunscreen as the product contains low levels of AHA.
No, this serum has a comedogenic rating of 0/5 and will not clog pores. The formula is oil-free and contains no known comedogenic ingredients. Glycerin, niacinamide, and the Aquaxyl complex are all non-comedogenic. In fact, niacinamide actively helps minimize the appearance of enlarged pores and regulate sebum production, making this an excellent choice for those prone to clogged pores and breakouts.
The serum has a Period After Opening (PAO) of 12 months. Once opened, use within one year for optimal efficacy. Store in a cool, dry place away from direct sunlight. The 30ml bottle typically lasts 2-3 months with nightly use of 2-3 drops. Signs the product may have expired include changes in color, texture, smell, or separation of ingredients.
Verdict: The ISANA Overnight Moisture Serum delivers exceptional value with its clinically-proven Aquaxyl technology and 5% niacinamide formula. At just €3.99 for 30ml, it's one of the most affordable yet effective hydrating serums on the market. The minimal 13-ingredient formula is pregnancy-safe, fungal acne-safe, and suitable for sensitive skin—making it accessible to nearly everyone. While it may not replace specialized anti-aging treatments, it excels as a daily hydration and skin barrier support product. Highly recommended for those seeking effective, no-frills skincare without breaking the bank.
Product Overview
What are Quick Product Notes?
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Pro Tip Alert!
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Paraben-Free
Paraben-Free
Understanding Parabens
Parabens are a large group of preservatives which are used to prevent bacteria growing in cosmetic formulations. There has been some healthy controversy surrounding them due to a few studies finding paraben presence in breast tumours and breast tissue. However, the majority of the scientific community have deemed these findings non-conclusive due to the limitations of these studies. There's still a lot of support for avoiding parabens following the better safe than sorry route. If you do we completely support you! If you are concerned about the health safety of parabens, then feel free to avoid them by looking out for the Paraben-Free icon. If not, don't worry about it - they do have had one of the longest safety records as preservatives!
Which Ingredients are classified as Paraben?
A product will be paraben-free if it does not contain any of the following parabens:
- Sodium Isobutylparaben
- Sodium Ethylparaben
- Sodium Butylparaben
- Propylparaben
- Isopropylparaben
- Isobutylparaben
- Sodium Propylparaben
- Butylparaben
- Ethylparaben
- Sodium Methylparaben
- Methylparaben
Sulfate-Free
Sulfate-Free
Understanding Sulfates
Sulfates are a large group of ingredients which act as cleansing agents in Cosmetics. They help loosen up the dirt and grime from your skin and hair to allow for water to wash it away with ease. However some sulfates are so good at their job, they can wash off your skin’s own natural oils that keep it moisturised and protected which can lead to dryness and irritation. Most people will find no issues with sulfate, however if you find your skin doesn't like sulfates then free feel to avoid them by looking out for the sulfate-free icon on Skincarisma.
Which ingredients are classified as sulfates?
We've taken the Sulfates which are considered more harsh for our Sulfate-Free status. A product will be Sulfate-Free if it does not contain any of the following Sulfates:
- TEA-Dodecylbenzenesulfonate
- Ammonium Laureth Sulfate
- Sodium Lauryl Sulfate
- PEG-15 Cocamine
- Sodium Laureth Sulfate
- Sodium Cocoyl Sarcosinate
- Sodium C14-16 Olefin Sulfonate
- Dioctyl Sodium Sulfosuccinate
- Ammonium Xylenesulfonate
- Ammonium Lauryl Sulfate
- Sodium Xylenesulfonate
- Sodium Myreth Sulfate
- Sodium Lauryl Sulfoacetate
Alcohol-Free
Alcohol-Free
Understanding Simple Alcohols
Alcohol ingredients are widely used in cosmetics and come in different types. For the most part alcohols are not problematic at all. However one type of alcohols, simple alcohols can be quite drying to the skin because it evaporates very quickly. This can cause irritation which can also lead to other skin complications. These alcohols should never be used alone on your skin, but combined with other cosmetic ingredients, they are normally without issue. However, for some people with sensitive and easily irritable skin, avoiding products with these simple alcohols may be beneficial. If you find your skin doesn't like these simple alcohols, then free feel to avoid them by looking out for the Alcohol-Free icon.
Which Ingredients are classified as Alcohol?
A product will be alcohol-free if it does not contain any of the following alcohol ingredients:
- SD Alcohol
- Alcohol Denat
- Isopropyl Alcohol
- Alcohol
Silicone-Free
Silicone-Free
Understanding Silicones
If you've ever used a skincare, makeup or beauty product that's made your skin look and feel smoother tempoarily - it's likely contained Silicone. They are a popular class of ingredients found in cosmetics due to their smooth, soft, easy-to-spread and smooth properties that help creates an artificial layer/barrier on top of skin or hair (commonly found in conditioners).
For the same reasons they are popularly used, they are also commonly avoided. Anecdotally, many individuals have reported that Silicones cause/excerbate breakouts, irritation, cause a feeling of skin being unable to breathe, cause clumping of cosmetic products and find it difficult to wash off. As a result, those who find them problematic are avoiding them and increasingly, cosmetic companies are avoiding them as well.
If you have had bad experiences with Silicones in the past, or suspect they are problematic then look out for the tick on the Silicone-free label.
Disclaimer
The Silicone-free label only includes the most common Silicone ingredients that have indentified been reported by individuals that could potentially cause issues.
These include: Amodimethicone, Behenoxy Dimethicone, Bis-Aminopropyl Dimethicone, Cetearyl Methicone, Cetyl Dimethicone, Cyclomethicone, Cyclopentasiloxane, Dimethicone, Dimethicone Copolyol, Dimethiconol, Methicone, Phenyl Trimethicone, Phenyl Trimethicone, Stearoxy Dimethicone, Stearyl Dimethicone, Trimethylsilylamodimethicone.
Note, that this does not include all ingredients part of the Silicone class of ingredients.
EU Allergen-Free
EU Allergen-Free
Understanding the Identified Contact Allergens
The EU's Scientific Committee on Consumer Safety (SCCS) has identified and established 26 cosmetic ingredients that are likely contact allergens (potential to cause skin allergies) as demonstrated in clinical or epidemiological studies. The EU's SCCS have recommend cosmetic companies to disclose them on the labels if used and in cases where the concentration exceeds 0.001% in leave-on products and 0.01% in rinse-off products, then they must be labelled.
Look out for the tick on the EU-Allergen free label to know your cosmetic is free from any of the 26 identified cosmetic ingredients.
For more information regarding the EU's Scientific Committee on Consumer Safety, please visit their official website.
Disclaimer
The EU Allergen Free label is for the 26 ingredients identified by the EU SCCS and products will be only flagged if a suspected ingredient is on it's ingredient list. It is possible for cosmetics to contain one of the suspect ingredients without it appearing on the ingredient list due to it not reaching the concentration threshold to disclose it and cosmetic manufacturers choice to not disclose it.
Also note, the EU Allergen Free label is not personalized for your own allergies you may have and it does not constitute as medical advice. For your specific case, always consult your medical professiona such as dermatologist, physician, pharmacist, or health care provider - please read our medical disclaimer for more information.
Fungal Acne (Molassezia) Safe
Fungal Acne (Molassezia) Safe
Understanding Fungal Acne (Pityrosporum Folliculitis/Malassezia Folliculitis)
Pityrosporum Folliculitis/Malassezia folliculitis or simply known as Fungal Acne is a persistent acne-like condition that commonly responds poorly to traditional acne-treating methods. Unlike most cases of Acne where bacteria is the culprit, Fungi is the culprit of Fungal Acne (Hence the name!). There are certain classes & groups of ingredients that have been shown to promote and feed the growth of the Fungal Acne, Fungi such as fatty acids, oils, esters, polysorbates and fermented ingredients.
For more information regarding Fungal Acne, please visit Simple Skincare Science (f.c) - #3 of our Recommend Skincare Resources for an amazing comprehensive guide!
Please Read: How to use the Fungal Acne (Malassezia) Label
At SkinCarisma, we've done our best to identify as many ingredients as possible but note the fungal-free label may not be 100% accurate due to the complexconditions and combination of ingredients that malezzeria can thrive on.
Additionally, products that may contain ingredients that have shown to feed Malassezia may not neccessarily exacerbate the condition due to concentration of ingredient used in the product, this information is simply not available on the products.
As a result, please note this is only an experimental label that can be best used to possible identify problematic products you have used in the past. It is in no way a perfect identifier nor a predictor in whether or not it will exacerbate or cause fungal acne. It will continue to be worked on as more information and research comes to light.
If you find any ingredients you believe should be included, please email us at snails@skincarisma.com.
Disclaimer
Due to the lack of substantial research into this area it is very likely there are other ingredients and class/groups of ingredients that could feed Fungal Acne which have not been indentified.
The Fungal-Safe label does not constitute as medical advice. For your specific case, always consult your medical professiona such as dermatologist, physician, pharmacist, or health care provider - please read our medical disclaimer for more information.
What are Notable Effects & Ingredients?
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Pro Tip Alert!
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Anti-Aging from 2 ingredient(s):
Brightening from 3 ingredient(s):
Promotes Wound Healing from 2 ingredient(s):
Ache-fighting from 1 ingredient(s):
What are Ingredients Related to Skin Type?
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
Pro Tip Alert!
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Dry Skin
Oily/Acne-Prone Skin
Sensitive Skin
What is the Ingredient Safety Breakdown?
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
Pro Tip Alert!
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Brightening
Promotes Wound Healing
Hydrating
|
|
| 4 |
Phenoxyethanol
Fragrance, Preservative
|
|
|
| 0 |
Xylitylglucoside
Humectant, Skin Conditioning
|
Hydrating
|
|
| 1 |
Xanthan Gum
Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant -Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling
|
|
|
| 0 |
Hydroxyacetophenone
|
Irritation
|