PDRN Pink Peptide Toner
PDRN Pink Peptide Toner
Product Description
Product overview
A lightweight, glow-boosting toner powered by Rose PDRN and a 5-peptide complex that hydrates, smooths texture, and preps skin for better absorption of following skincare. Clinically tested to improve skin moisture by 53% and radiance by 19%.
Rose PDRN Technology
Salmon DNA fragments derived from rose extract support skin renewal and help improve overall skin radiance and tone.
Texture & feel
SENSORYRose PDRN Technology
Salmon DNA fragments derived from rose extract support skin renewal and help improve overall skin radiance and tone.
5-Peptide Complex
Copper Tripeptide-1, Acetyl Hexapeptide-8, and Matrixyl peptides help firm skin and reduce appearance of fine lines.
Niacinamide + Adenosine
Clinically proven brightening and anti-aging ingredients work together to even skin tone and improve texture.
Centella Asiatica (Cica)
Soothing botanical extract helps calm irritation and strengthen the skin barrier for healthier-looking skin.
Safety & compatibility
SAFENo retinoids, salicylic acid, hydroquinone, or chemical sunscreens. Safe for use during pregnancy and nursing.
Contains Polyglyceryl-10 Laurate, Polyglyceryl-4 Laurate, and Arginine which may trigger fungal acne in susceptible individuals.
Rating 1/5. Oil-free, lightweight formula unlikely to clog pores for most skin types.
Dermatologist-tested, low-irritation formula. Patch test recommended for very reactive skin.
Ingredient breakdown
INGREDIENTSRose PDRN (Sodium DNA)Emerging
Polydeoxyribonucleotide (PDRN) derived from salmon DNA. Supports skin cell renewal, helps strengthen the skin barrier, and promotes a more even, radiant complexion.
- Function: Cell regeneration support, barrier strengthening, anti-aging
- Research: Most studies are on injectable forms; topical effects are milder but show promise for skin renewal
5-Peptide ComplexProven
A powerful blend of Copper Tripeptide-1 (GHK-Cu), Acetyl Hexapeptide-8 (Argireline), Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, and Palmitoyl Tripeptide-1.
- Copper Tripeptide-1: Stimulates collagen production, wound healing, antioxidant effects
- Acetyl Hexapeptide-8: Known as "Botox in a jar" - helps relax expression lines
- Matrixyl Peptides: Clinical studies show wrinkle reduction comparable to 0.07% retinol
Niacinamide (Vitamin B3)Proven
Multi-functional superstar ingredient that brightens skin, strengthens the barrier, regulates sebum, and improves texture.
- Brightening: Inhibits melanin transfer for more even skin tone
- Barrier Support: Increases ceramide production
- Anti-Aging: Reduces fine lines and wrinkles with consistent use
Centella Asiatica ExtractProven
Traditional healing herb (also known as Cica or Tiger Grass) with powerful soothing and barrier-repair properties.
- Active Compounds: Madecassoside, Asiaticoside, Madecassic Acid, Asiatic Acid
- Benefits: Anti-inflammatory, promotes collagen synthesis, calms redness
36 ingredients
Water, Butylene Glycol, Glycerin, Niacinamide, 1,2-Hexanediol, Xylitol, Sodium Citrate, Ethylhexylglycerin, Allantoin, Caprylyl Glycol, Citric Acid, Adenosine, Polyglyceryl-10 Laurate, Disodium EDTA, Polyglyceryl-4 Laurate, Caprylyl/Capryl Glucoside, Cyanocobalamin, Rosa Damascena Extract, Sodium DNA, Gluconolactone, Prunus Mume Fruit Extract, Pyrus Malus (Apple) Fruit Extract, Carica Papaya (Papaya) Fruit Extract, Vitis Vinifera (Grape) Fruit Extract, Centella Asiatica Leaf Extract, Centella Asiatica Extract, Sodium Hyaluronate, Zea Mays (Corn) Leaf Extract, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Glycine, Glutamic Acid, Arginine
Where it fits in your routine
ROUTINEUse after cleansing as the first step of your skincare routine. Apply morning and evening for best results.
How to use
HOW TO USECleanse Your Face
Start with a clean, freshly washed face. Pat skin until slightly damp but not dripping wet.
Dispense Toner
Pour an appropriate amount onto a cotton pad or directly into clean palms. A quarter-sized amount is usually sufficient.
Apply to Face
Gently pat or swipe across entire face and neck, avoiding eye area. Can also be used for the 7-skin method (layering thin layers).
Continue Routine
Follow with essence, serum, and moisturizer. No need to wait between steps - the toner absorbs quickly.
Who is it for?
WHOPerfect for you if:
- You want to boost skin radiance and achieve glass skin
- Your skin looks dull, tired, or lacks glow
- You have uneven skin tone or texture concerns
- You want anti-aging benefits without harsh actives
- You prefer lightweight, fast-absorbing products
- You are pregnant or breastfeeding
- You want to prep skin for better serum absorption
Consider alternatives if:
- You have fungal acne (malassezia folliculitis)
- You are vegan (contains salmon-derived PDRN)
- You need heavy hydration for extremely dry skin
- You prefer fragrance in your skincare
- You have severe acne requiring medical treatment
- You are allergic to fish or fish-derived ingredients
Skin type compatibility
SKIN TYPESLightweight, watery texture absorbs instantly without adding shine. Helps balance sebum production.
Provides hydration prep layer but may need heavier moisturizer on top. Layer multiple times for more hydration.
Balances well across different face zones. Lightweight enough for T-zone, hydrating for dry cheeks.
Fragrance-free, dermatologist-tested formula. Contains soothing Centella. Patch test recommended for very reactive skin.
Low comedogenic rating but not fungal acne safe. Non-irritating formula with niacinamide may help with PIH.
Results timeline
WEEK 8+Instant Hydration & Glow
Immediate improvement in skin hydration and surface radiance. Skin feels softer and more supple after each application.
53% reported moisture improvementTexture & Tone Improvement
Noticeable improvement in skin texture smoothness. Skin tone appears more even and bright. Clinical tests show 6.4% skin tone improvement.
19% reported radiance improvementVisible Anti-Aging Benefits
Peptide complex begins showing visible results on fine lines. Skin appears firmer and more elastic. Barrier function strengthened.
3.7% texture improvement reportedLong-Term Skin Health
Cumulative benefits of PDRN and peptides become more apparent. Overall skin health and resilience improved with consistent use.
Best results with continued useRatings by platform
REVIEWSPros & cons
BALANCEDPraised
- Instant glow and hydration boost
- Lightweight, non-sticky texture
- Fragrance-free and low irritation
- Pregnancy and breastfeeding safe
- Clinically tested with proven results
- Works well under makeup
- Absorbs quickly, no wait time needed
- Contains proven anti-aging peptides
Criticized
- Not fungal acne safe
- Not vegan (salmon-derived PDRN)
- Pink color may seem unusual at first
- May not be hydrating enough alone for very dry skin
- PDRN research is still emerging for topical use
- Premium price point for a toner
Budget-friendly alternatives (dupes)
DUPESContains 84% Centella Asiatica extract with PHA for gentle exfoliation. Similar soothing benefits but no PDRN or peptides. Great for sensitive skin on a budget.
Pioneer of PDRN in K-Beauty. Contains salmon PDRN with 3 types of hyaluronic acid. Larger 300ml size. Less peptide variety but similar core technology.
Contains salmon PDRN, NAD+, and 50 peptides. Violet shimmer from ceramides and B12. Smaller 150ml size but very feature-rich formula.
Comparison with competitors
SIDE-BY-SIDEnumbuzin No.9 NAD+ PDRN Toner
Storage & shelf life
12 MONTHS12 months after opening
Store in a sealed container away from direct sunlight at 59-77°F (15-25°C) for optimal preservation
Plastic bottle with flip-cap or pump dispenser
No (250ml exceeds 100ml carry-on limit). Decant into smaller container for travel.
Frequently asked questions
FAQYes! This toner is considered safe during pregnancy and breastfeeding. It does not contain retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients typically flagged as unsafe during pregnancy. The formula focuses on gentle, hydrating ingredients like peptides, niacinamide, and PDRN which are not contraindicated during pregnancy.
No, this toner is NOT fungal acne safe. It contains several ingredients that may feed the malassezia yeast, including Polyglyceryl-10 Laurate, Polyglyceryl-4 Laurate, and Arginine (in the presence of lipids). If you are prone to fungal acne, consider alternatives like SKIN1004 Madagascar Centella Toning Toner which is fungal acne safe.
Yes, this toner is compatible with most actives. Niacinamide and peptides work well with retinol and vitamin C. The gentle, hydrating formula can actually help buffer irritation from stronger actives. However, if using exfoliating acids (AHA/BHA), you may want to apply them after the toner or on alternate days to avoid over-exfoliation. The toner contains a small amount of gluconolactone (PHA) which is very gentle.
This toner works best for oily, combination, normal, and sensitive skin types. Its lightweight, watery texture makes it excellent for oily skin as it provides hydration without added greasiness. Dry skin types can still use it but may need to layer it multiple times or follow with a heavier moisturizer. The low-irritation, fragrance-free formula makes it suitable for sensitive skin. It's NOT ideal for those with fungal acne.
Results timeline varies: Immediate hydration and glow can be noticed after first use. Clinical studies show 53% moisture improvement. Texture and tone improvements typically become noticeable within 2-4 weeks of consistent use (clinical tests showed 6.4% skin tone improvement). Anti-aging benefits from peptides usually take 4-8 weeks of consistent twice-daily use to become visible. Best results come with continued long-term use.
Apply this toner immediately after cleansing as the first step of your skincare routine. The order should be: Cleanser → This Toner → Essence → Serum → Moisturizer → Sunscreen (AM only). The toner prepares skin for better absorption of following products. It can be used both morning and evening. You can also use the "7-skin method" by layering thin applications for extra hydration.
This toner has a low comedogenic rating of 1/5, meaning it is unlikely to clog pores for most people. The oil-free, lightweight formula absorbs quickly without leaving residue. However, if you are prone to fungal acne (which can look similar to clogged pores), this product may cause breakouts due to ingredients that feed malassezia yeast. Patch test if you have very acne-prone skin.
The toner has a PAO (Period After Opening) of 12 months. Store in a cool, dry place away from direct sunlight at 59-77°F (15-25°C) for optimal preservation. The 250ml bottle typically lasts 2-3 months with twice-daily use, well within the 12-month window. If you notice any changes in color, smell, or texture, discontinue use.
Verdict: The Medicube PDRN Pink Peptide Toner delivers on its promise of boosting skin radiance and hydration with its innovative PDRN and 5-peptide formula. It's an excellent choice for those seeking glass skin and gentle anti-aging benefits without harsh actives. The fragrance-free, low-irritation formula makes it suitable for sensitive and pregnant/nursing individuals. However, it's not recommended for fungal acne-prone skin or vegans. At its price point, it offers good value with clinically-proven results. Consider the SKIN1004 Centella Toner as an alternative if you need fungal acne safety.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 1 |
Butylene Glycol
Solvent, Skin Conditioning, Masking, Fragrance, Humectant, Viscosity Controlling, Viscositydecreasing Agent
|
Hydrating
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 1 |
Niacinamide
Skin Conditioning, Hair Conditioning, Smoothing
|
Promotes Wound Healing
Redness
Irritation
Dark Spots
Pores
|
|
| 1 |
1,2-Hexanediol
Solvent, Skin Conditioning
|
Hydrating
|




