Probioderm Collagen Remodeling Serum
Probioderm Collagen Remodeling Serum
Product Description
Product overview
A lightweight, fast-absorbing pore-correcting serum from BIOHEAL BOH. This renewed 2024 formula combines patented Thermacollagen™ capsules, a 12-peptide complex, probiotic Lactobacillus ferments and gentle PHA + LHA exfoliants to create a "corset-like" tightening effect that visibly refines pores and boosts elasticity — with brand testing showing reduced pore area in as little as 5 days.
Pore "Corset" Effect
Targets both horizontal and vertical pores to visibly tighten and refine skin surface for a smoother texture.
Texture & feel
SENSORYPore "Corset" Effect
Targets both horizontal and vertical pores to visibly tighten and refine skin surface for a smoother texture.
Double Elastic Liposome™
Encapsulated actives release over time, with brand testing noting pore-correcting effects that persist up to a week after stopping use.
Probiome Ferment Blend
Lactobacillus and Lactococcus postbiotics help support the skin barrier and a balanced microbiome.
Gentle Resurfacing
Gluconolactone (PHA) and Capryloyl Salicylic Acid (LHA) smooth and refine without the sting of stronger acids.
Safety & compatibility
SAFEContains Capryloyl Salicylic Acid (an LHA / salicylic-acid derivative) and added fragrance. Topical use is low-risk at these levels, but check with your OB-GYN before use.
Includes ferment lysates, stearic acid, cetearyl alcohol and several palmitoyl peptides that can feed Malassezia.
Hydrating toners, niacinamide, hyaluronic acid, ceramide moisturizers and daytime SPF.
Already contains gentle PHA + LHA. Avoid stacking with strong AHA/BHA or high-strength retinoids in the same routine to limit irritation.
Formulated with Parfum and Camellia Sinensis Leaf Water. Sensitive or fragrance-reactive skin should patch test first.
Brand states the formula is dermatologically tested for irritation and free from parabens, silicones and sulfates.
Ingredient breakdown
INGREDIENTSCollagen + Collagen Extract ~20 ppm eachPromising
BIOHEAL BOH's signature "Thermacollagen™" sits at the heart of this serum, delivered in heat-responsive capsules that burst on skin for an immediate plumping, smoothing feel.
- Hydration: Collagen is an excellent humectant; well-hydrated skin looks firmer and shows fewer fine lines.
- Texture: The capsule "burst" delivery gives the instant tightening sensation users describe.
12-Peptide Complex (Matrixyl, GHK-Cu & more) <0.1% totalProven
A signal-peptide blend including Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1 + Tetrapeptide-7 (Matrixyl 3000), Copper Tripeptide-1 (GHK-Cu) and Acetyl Hexapeptide-8 (Argireline).
- Collagen signaling: Matrixyl peptides cue skin to produce more collagen, supporting firmness over time.
- Expression lines: Argireline-type peptides help relax micro-movements that form fine lines.
Probiome Ferment Blend High in listPromising
Lactobacillus Ferment Lysate, Lactobacillus Ferment and Lactococcus Ferment Lysate are postbiotics — inactive molecules from probiotic bacteria.
- Barrier support: Studies show lactobacillus ferment can help repair and strengthen the skin barrier.
- Soothing: May help calm redness, though evidence is still emerging.
Gluconolactone (PHA) Mid listProven
A polyhydroxy acid — a gentler cousin of AHAs that dissolves dead surface cells to brighten and smooth.
- Gentle: Its larger molecule penetrates slowly, causing less irritation than glycolic or lactic acid.
- Antioxidant: Also acts as a humectant and free-radical scavenger.
Capryloyl Salicylic Acid (LHA) Mid listProven
A lipophilic salicylic-acid derivative that helps clear excess oil from pores and refine texture.
- Pore care: Helps break down oil inside pores, complementing the serum's tightening claims.
- Low irritation: Its large molecule stays mostly in the upper skin layer, making it gentler than standard BHA.
Centella Asiatica + Adenosine + Beta-Glucan SupportingProven
A soothing, anti-aging support trio rounding out the formula alongside Ceramide NP and Tocopherol (Vitamin E).
- Centella: Calms, hydrates and supports barrier repair.
- Adenosine: A well-studied anti-wrinkle active that smooths and firms.
- Beta-Glucan: Deeply hydrating antioxidant that helps reduce the look of wrinkles.
70 ingredients
Water, Lactobacillus Ferment Lysate, Propanediol, Glycerin, Methylpropanediol, 1,2-Hexanediol, Lactobacillus Ferment, Collagen, Collagen Extract, Potentilla Anserina Extract, Avena Sativa Kernel Extract, Cynara Scolymus Leaf Extract, Centella Asiatica Extract, Cyperus Rotundus Root Extract, Oenothera Biennis Flower Extract, Ulmus Davidiana Root Extract, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Hydrogenated Lecithin, Camellia Sinensis Leaf Water, Phytosterols, Arachidyl Alcohol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Stearic Acid, Panthenol, Behenyl Alcohol, Ethylhexylglycerin, Carbomer, Arachidyl Glucoside, Caprylic/Capric Triglyceride, Tromethamine, Adenosine, Polyacrylate Crosspolymer-6, Polyquaternium-51, Butylene Glycol, Beta-Glucan, Glyceryl Polymethacrylate, Cetearyl Alcohol, Ceramide NP, Lactococcus Ferment Lysate, Sorbitan Isostearate, Fructooligosaccharides, Glycosaminoglycans, Gluconolactone, Capryloyl Salicylic Acid, Hydrolyzed Elastin, Betaine, Cyanocobalamin, Tocopherol, Sodium Chloride, Nonapeptide-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8, Xanthan Gum, Copper Tripeptide-1, Tannic Acid, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Hexapeptide-12, Pentapeptide-3, Hexapeptide-9, Fructan, Sucrose Distearate, Inulin, Hydroxypropyl Cyclodextrin, Parfum.
Where it fits in your routine
ROUTINEApply after toner and before heavier creams. Use morning and evening, and always follow with SPF during the day.
How to use
HOW TO USECleanse & Tone
Start with clean skin and a hydrating toner so the serum spreads evenly.
Dispense a Pea-Sized Amount
A little goes a long way — most users find 2–3 drops covers the whole face.
Apply & Pat In
Smooth over the face, focusing on enlarged pores, then gently pat to aid absorption.
Seal & Protect
Follow with moisturizer, and finish with sunscreen every morning.
Who is it for?
WHOPerfect for you if:
- You want to visibly refine and tighten enlarged pores
- You're after early anti-aging and elasticity support
- You prefer a lightweight, non-greasy serum for AM & PM
- You like peptide- and ferment-rich K-beauty formulas
- You want gentle resurfacing without strong acids
Consider alternatives if:
- You're prone to fungal acne (Malassezia)
- You need a strictly fragrance-free formula
- You're pregnant and avoiding all salicylic derivatives
- You want a clinically proven retinoid for deep wrinkles
- You have very dry skin needing rich occlusion alone
Skin type compatibility
SKIN TYPESLightweight and non-sticky; the LHA helps manage oil and refine pores without heaviness.
Balances hydration and oil control well across both the T-zone and cheeks.
Hydrating and barrier-friendly, but very dry skin will want a richer cream layered on top.
Soothing ferments and centella help, but added fragrance means a patch test is wise.
Low comedogenic risk and helpful LHA — but not suitable if your breakouts are fungal acne.
The 12-peptide complex, adenosine and collagen target elasticity and firmness directly.
Results timeline
4–8 WEEKSSmoother, Plumper Feel
Collagen capsules burst on application for an immediate tightening, hydrated finish.
Most users noticeRefined Pore Appearance
Brand testing reports a visible reduction in pore area with consistent twice-daily use.
Per brand claimTexture & Elasticity
Human-efficacy testing cited by the brand notes improved elasticity, texture and moisture.
Per brand studyFirmer, Bouncier Skin
Peptide signaling and adenosine support cumulative firmness and fine-line smoothing.
With continued useRatings by platform
10K+ REVIEWSPros & cons
BALANCEDPraised
- Lightweight, fast-absorbing and non-sticky
- Genuinely impressive peptide + ferment ingredient list
- Visibly smoother, plumper skin and refined pores
- Gentle PHA/LHA resurfacing suits most skin types
- Pleasant collagen-capsule "burst" sensation
Criticized
- Contains fragrance — not for fragrance-sensitive skin
- Not fungal-acne (Malassezia) safe
- Small 30ml size relative to price
- Topical collagen benefits are mainly surface-level
- Results can be subtler than the bold "5-day" marketing
Budget-friendly alternatives (dupes)
DUPESA peptide-and-hyaluronic-acid serum at a lower price. It shares the peptide focus but lacks the ferments, PHA/LHA exfoliants and collagen-capsule texture.
Bigger bottle, collagen + niacinamide + HA focus for plumping and glass-skin bounce. Less peptide variety and no LHA pore-clearing action.
Brightening, ferment-rich essence with niacinamide. Great glow and hydration, but it's not built around pore-tightening peptides and collagen.
Comparison with competitors
SIDE-BY-SIDEBIOHEAL BOH Probioderm Serum
Storage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight; close cap tightly after use.
Pump bottle that helps protect the encapsulated actives from air and light.
Yes — 30 ml is well under the 100 ml carry-on liquid limit.
Frequently asked questions
FAQIt contains Capryloyl Salicylic Acid (an LHA / salicylic-acid derivative) and added fragrance. Topical salicylic derivatives at low cosmetic levels are generally considered low-risk, but many practitioners advise caution during pregnancy and breastfeeding. We recommend checking with your OB-GYN or doctor before adding it to your routine.
No. The formula includes ferment lysates, stearic acid, cetearyl alcohol, sorbitan isostearate, sucrose distearate and several palmitoyl peptides — ingredients that can feed Malassezia yeast. If you're managing fungal acne, this serum isn't the best fit.
It already contains gentle PHA and LHA, so stacking it with strong AHA/BHA or high-strength retinoids in the same routine can over-exfoliate and irritate. Vitamin C pairs fine (ideally AM, with SPF). If you use retinol, alternate it on different nights and listen to your skin.
It shines on oily, combination and mature skin thanks to its lightweight texture, pore-refining LHA and firming peptide complex. Dry skin can use it under a richer cream, while sensitive or fragrance-reactive skin should patch test first.
You'll feel an instant plumping, tightened sensation on application. The brand cites visibly refined pores in about 5 days and improved elasticity, texture and moisture around 2 weeks of twice-daily use. Firming peptide benefits build over roughly 4–8 weeks of consistent use.
Use it after cleansing and toner, before eye cream and moisturizer. Apply morning and evening, and always finish with sunscreen in the daytime.
Overall comedogenic risk is low (about 2/5). It's marketed as lightweight and non-pore-clogging, and most oily and acne-prone users tolerate it well. The main caveat is that it isn't fungal-acne safe, which is a separate concern from comedogenicity.
Around 12 months after opening (12M PAO). Keep it sealed, stored away from heat and sunlight, and discard if the color, scent or texture noticeably changes.
Verdict: The BIOHEAL BOH Probioderm Collagen Remodeling Serum is a genuinely well-built K-beauty pore-and-elasticity serum, pairing a generous 12-peptide complex, probiotic ferments and gentle PHA/LHA in a lightweight, fast-absorbing texture that oily, combination and mature skin types love. Brand testing backs up visibly refined pores and improved elasticity, and most users enjoy the instant plumping feel. It loses points for added fragrance, a not-fungal-acne-safe formula and a modest 30ml size — but for anyone chasing smoother texture, tighter-looking pores and early anti-aging support, it's a strong, easy-to-layer pick.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 1 |
Lactobacillus Ferment Lysate
Skin Conditioning
|
|
|
| 1 |
Propanediol
Solvent, Viscosity Controlling, Viscosity Decreasing Agent
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 1 |
Methylpropanediol
Solvent
|
|






