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Purifying Active Cleansing Gel

Purifying Active Cleansing Gel

Product Description

Product overview

Made in Various INTERNATIONAL

A medical-grade purifying gel cleanser formulated with BIOPEP-15 antimicrobial peptide and piroctone olamine to deeply cleanse oily, acne-prone skin without stripping moisture. This dermatologist-developed formula regulates excess sebum, reduces bacterial proliferation, and leaves skin mattified, fresh, and balanced.

Dermatologically Tested Non-Comedogenic pH Balanced (5-6) Ophthalmologist Tested Paraben-Free Dye-Free
Pregnancy
Caution
Fungal Acne
No
Comedogenic
0/5
Type
Gel Cleanser
Size
200ml / 400ml
pH Level
5.0 - 6.0
Target
Acne-Prone
Brand
Cantabria Labs
Real reviews · YouTube Shorts
Why it's different

BIOPEP-15 Technology

Patented antimicrobial peptide that selectively targets C. acnes bacteria to prevent breakouts without disrupting skin microbiome.

01

Texture & feel

SENSORY
Consistency
Lightweight Gel
Scent
Light Fresh
Absorption
Rinses Clean
Finish
Matte, Fresh

BIOPEP-15 Technology

Patented antimicrobial peptide that selectively targets C. acnes bacteria to prevent breakouts without disrupting skin microbiome.

Sebum Regulation

Piroctone olamine and botanical extracts work together to control excess oil production and provide mattifying effects.

Gentle Exfoliation

Gluconolactone (PHA) provides mild exfoliation to remove dead skin cells without irritation or dryness.

Soothing Botanicals

Aloe vera, witch hazel, and propolis extracts calm inflammation and support skin healing from breakouts.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding

Consult your healthcare provider. While the cleanser itself doesn't contain retinoids, the Biretix brand includes retinoid products. Always verify with your doctor.

Fungal Acne (Malassezia)

Not recommended. Contains PEG-150 Pentaerythrityl Tetrastearate and botanical extracts that may feed malassezia yeast.

Sensitive Skin

Dermatologically and ophthalmologically tested. Suitable for sensitive, acne-prone skin with proper patch testing.

Use with Actives

Compatible with prescription acne treatments including adapalene, benzoyl peroxide, and clindamycin. Non-drying formula supports barrier function.

03

Ingredient breakdown

INGREDIENTS

BIOPEP-15 (Oligopeptide-10)Patented

A bioactive antimicrobial peptide developed by Cantabria Labs that selectively targets Cutibacterium acnes bacteria. It disrupts bacterial biofilms and reduces inflammatory lesions without harming beneficial skin flora.

  • Mechanism: Disrupts C. acnes biofilm formation
  • Clinical Data: Studies show significant reduction in inflammatory lesions within 4-8 weeks
  • Benefit: Anti-inflammatory and antimicrobial without antibiotic resistance
Maintains healthy skin microbiome while targeting acne-causing bacteria

Piroctone Olamine ~0.5%Proven

An antifungal and antibacterial agent commonly used in anti-dandruff products. In skincare, it helps control sebum, fights bacteria, and has anti-inflammatory properties.

  • Source: Synthetic compound with excellent safety profile
  • Research: Effective against Malassezia and bacteria at low concentrations
  • Comedogenic Rating: 0 - Non-comedogenic

Gluconolactone (PHA)Proven

A polyhydroxy acid that provides gentle exfoliation while also acting as a humectant. Unlike AHAs, PHAs are larger molecules that don't penetrate as deeply, making them suitable for sensitive skin.

  • Function: Gentle exfoliation and hydration
  • Benefit: Improves skin texture without irritation
  • Comparison: Gentler than glycolic acid, ideal for sensitive skin

Aloe Barbadensis GelProven

A well-known soothing and hydrating ingredient with anti-inflammatory properties. Contains polysaccharides that help retain moisture and support skin healing.

  • Benefits: Soothing, hydrating, anti-inflammatory
  • Contains: Vitamins, minerals, and amino acids
  • Research: Supports wound healing and reduces redness

Hamamelis Virginiana (Witch Hazel)Traditional

A botanical extract with natural astringent, antioxidant, and anti-inflammatory properties. Contains tannins that help tighten pores and reduce oil.

  • Active Compounds: Hamamelitannin, catechins, gallic acid
  • Function: Astringent, anti-inflammatory, antibacterial
  • Best For: Oily and acne-prone skin

28 ingredients

Aqua, Propylene Glycol, Decyl Glucoside, Cocamidopropyl Betaine, TEA-Lauryl Sulfate, Propanediol, Sodium Laureth Sulfate, Disodium Laureth Sulfosuccinate, Cocamide DEA, Aloe Barbadensis Gel, Algae Extract, Propolis Extract, Hamamelis Virginiana Leaf Extract, Oryza Sativa Bran Extract, Boswellia Serrata Extract, Mel Extract, Oligopeptide-10, PEG-150 Pentaerythrityl Tetrastearate, Gluconolactone, Disodium EDTA, Piroctone Olamine, Sodium Benzoate, Butylene Glycol, Calcium Gluconate, Citric Acid, Potassium Sorbate, Parfum, Phenoxyethanol.

FREE FROM: Parabens, Dyes, Retinoids, Silicones, Mineral Oil, Alcohol (Denat.)
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Treatment
4
Serum
5
Moisturizer
6
Sunscreen (AM)

Use morning and evening as the first step of your skincare routine. Can be used with prescription acne treatments.

05

How to use

HOW TO USE
1

Wet Your Face

Splash lukewarm water onto your face and neck to prepare skin for cleansing.

2

Apply Gel

Dispense a small amount (about half a pump) onto fingertips. A little goes a long way with this concentrated formula.

3

Massage Gently

Work into a light lather using circular motions for 60 seconds. Focus on oily areas like T-zone.

4

Rinse Thoroughly

Rinse completely with lukewarm water. Pat dry gently with a clean towel and continue with your routine.

06

Who is it for?

WHO

Perfect for you if:

  • You have oily or combination skin with excess sebum
  • You struggle with acne, blackheads, or frequent breakouts
  • You want a cleanser that works with prescription acne treatments
  • You need a mattifying cleanser that doesn't over-dry
  • You're looking for dermatologist-grade skincare
  • You're a teenager or adult dealing with hormonal acne

Consider alternatives if:

  • You have fungal acne (malassezia folliculitis)
  • You have very dry or dehydrated skin
  • You're pregnant or breastfeeding (consult doctor first)
  • You prefer completely fragrance-free products
  • You need a makeup-removing cleanser (use oil cleanser first)
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Specifically formulated for oily skin. Controls sebum, mattifies, and deeply cleanses without stripping natural moisture.

Combination Skin
Excellent

Balances oily T-zone while being gentle enough for drier areas. Perfect for combination skin types.

Acne-Prone
Excellent

BIOPEP-15 and piroctone olamine actively target acne-causing bacteria. Non-comedogenic formula won't clog pores.

Sensitive Skin
Good

Dermatologically tested with soothing ingredients. Contains surfactants that may be too strong for very reactive skin.

Dry Skin
Moderate

May feel slightly drying. If used, follow immediately with a hydrating moisturizer. Better alternatives exist for dry skin.

08

Results timeline

ONGOING USE
Week 1-2

Initial Cleansing Benefits

Skin feels cleaner and less oily throughout the day. Excess shine is visibly reduced and pores appear cleaner.

81% noticed matte finish
Week 2-4

Reduced Breakouts

New breakouts become less frequent as BIOPEP-15 works to disrupt acne-causing bacteria. Existing blemishes begin to heal faster.

95% reported effective cleansing
Week 4-8

Clearer Complexion

Significant reduction in inflammatory lesions. Skin texture improves and post-acne marks begin to fade with consistent use.

Clinical results show reduced lesions
Ongoing Use

Maintenance & Prevention

Continued use prevents new breakouts and maintains sebum balance. Best results when used as part of complete Biretix routine.

Recommended for long-term use
09

Ratings by platform

1K+ REVIEWS
SkinLovers
4.6
Rating
1,100+
Reviews
Main complaint: Can feel slightly drying for those with very sensitive skin
Brand Website
4.8
Rating
95%
Effective
Main complaint: Higher price point compared to drugstore cleansers
Pharmacy Reviews (EU)
4.7
Rating
500+
Reviews
Main complaint: 200ml size runs out quickly with twice daily use
Dermatologist Recommended
5.0
Expert Rating
Clinically
Proven
Note: Best results when used with complete Biretix regimen
10

Pros & cons

BALANCED

Praised

  • Effectively controls oil without over-drying
  • Patented BIOPEP-15 technology targets acne bacteria
  • Non-comedogenic and won't clog pores
  • Works well with prescription acne treatments
  • Dermatologically and ophthalmologically tested
  • Leaves skin feeling fresh without tightness
  • Medical-grade quality from reputable Spanish lab
  • Contains soothing ingredients to reduce irritation

Criticized

  • Higher price point than drugstore alternatives
  • Not suitable for fungal acne sufferers
  • Contains light fragrance (parfum)
  • 200ml size may not last long with twice daily use
  • Limited availability outside Europe
  • May be too drying for very dry skin types
  • Contains sulfates which some prefer to avoid
11

Budget-friendly alternatives (dupes)

DUPES
80% Match
Acne Foaming Cream Cleanser
$15.99
Budget Pick

Contains 4% benzoyl peroxide instead of BIOPEP-15. Includes ceramides for barrier support. More widely available but may be more drying.

75% Match
+M Effaclar Purifying Foaming Gel
$15.99
Similar Price

Contains zinc pidolate for oil control instead of antimicrobial peptides. French pharmacy quality with thermal spring water. Good for sensitive oily skin.

70% Match
0.5% Piroctone Olamine Cream
$12.99
Budget Pick

Same piroctone olamine antifungal ingredient plus salicylic acid. Sulfate-free formula. UK brand, good for seborrheic dermatitis and acne.

65% Match
The Real Noni Acne Bubble Cleanser
$14.00
Budget Pick

K-beauty option with piroctone olamine. Fungal acne safe formula. More gentle surfactants but lacks the antimicrobial peptide technology.

12

Comparison with competitors

SIDE-BY-SIDE
Effaclar A.Z. Gel Cream
Key ActiveZinc Pidolate
Sebum ControlZinc PCA
Size Options200ml / 400ml
Fungal Acne SafeNo
Best ForSensitive Oily
Acne Control Cleanser
Key Active2% Salicylic Acid
Sebum ControlHectorite Clay
Size Options237ml
Fungal Acne SafeYes
Best ForAll Acne Types
Clear Pore Normalizing Cleanser
Key Active0.5% Salicylic Acid
Sebum ControlGentle Formula
Size Options177ml / 473ml
Fungal Acne SafeYes
Best ForSensitive Acne
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening

Storage

Store at room temperature away from direct sunlight. Keep in a cool, dry place.

Packaging

Plastic bottle with pump dispenser (200ml) or refill bottle (400ml)

Travel Friendly

200ml bottle exceeds 100ml carry-on limit. Decant into smaller container for air travel.

13

Frequently asked questions

FAQ

Caution is advised. While the cleanser itself does not contain retinoids, the Biretix brand includes products with RetinSphere technology (retinoids). The official brand FAQ recommends consulting your healthcare provider if you are pregnant or breastfeeding. Some retailers include vitamin A warnings as a precaution for the entire product line.

No, this cleanser is not recommended for fungal acne. It contains PEG-150 Pentaerythrityl Tetrastearate (an ester) and various botanical extracts including propolis and honey that may feed malassezia yeast. While piroctone olamine has antifungal properties, the overall formula is not optimized for fungal acne sufferers.

Yes! The Biretix cleanser is formulated to work alongside prescription and over-the-counter acne treatments. Its non-drying formula with soothing ingredients like aloe vera helps support skin tolerance when using active ingredients. Many dermatologists recommend it specifically for patients on adapalene, benzoyl peroxide, or retinoid treatments.

This cleanser is specifically formulated for oily, combination, and acne-prone skin. It excels at controlling excess sebum and reducing shine while targeting acne-causing bacteria. It's dermatologically tested for sensitive skin but may be too drying for those with dry or dehydrated skin types.

Most users notice oil control and a matte finish within the first 1-2 weeks. According to brand studies, 81% of users report reduced shine early on. Significant improvement in breakouts typically occurs within 4-8 weeks of consistent twice-daily use. For best results, use as part of the complete Biretix regimen.

Use as the first step of your morning and evening skincare routine. Apply to wet skin, massage for 60 seconds, then rinse thoroughly. If wearing makeup or sunscreen, you may want to use an oil cleanser first for double cleansing. Follow with toner, treatments, serum, moisturizer, and sunscreen (AM only).

No, Biretix Purifying Cleansing Gel is officially labeled as non-comedogenic by the manufacturer. It's tested to ensure it won't clog pores. The formula is designed specifically for acne-prone skin and has a comedogenic rating of 0/5 based on its key ingredients.

The product has a PAO (Period After Opening) of 12 months. Once opened, use within one year for optimal effectiveness. With twice-daily use, the 200ml bottle typically lasts 2-3 months, while the 400ml refill size lasts 4-6 months. Store in a cool, dry place away from direct sunlight.

— Skincarisma verdict
4.5 / 5 ★★★★★

Verdict: Biretix Purifying Active Cleansing Gel is a medical-grade cleanser that delivers on its promises for oily and acne-prone skin. The patented BIOPEP-15 technology sets it apart from standard acne cleansers, offering targeted antibacterial action without the downsides of traditional antimicrobials. With 95% of users reporting effective cleansing and clinical backing from Cantabria Labs, this is a serious contender for anyone battling breakouts. The main drawbacks are its higher price point compared to drugstore options and incompatibility with fungal acne. If you have oily, acne-prone skin and want pharmaceutical-grade results, this cleanser is well worth the investment.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 2 ingredient(s):
Gluconolactone Citric Acid
brightening Brightening from 1 ingredient(s):
Citric Acid
wound Promotes Wound Healing from 2 ingredient(s):
Propolis Extract Citric Acid
ache Ache-fighting from 1 ingredient(s):
Propolis Extract
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
1 1
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
34% 23% 42%

Product ingredient list

Showing first 5 of 26 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
3 B
Propylene Glycol
Solvent, Skin Conditioning, Fragrance, Humectant, Viscosity Controlling, Viscosity Decreasing Agent, Skin-Conditioningagent - Miscellaneous
Hydrating
1 B
Decyl Glucoside
Surfactant, Emulsion Stabilising, Cleansing
4 B
Cocamidopropyl Betaine
Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent, Antistatic Agent, Hair Conditioning, Sufactant, Foam Boosting
1 Unknown
Propanediol
Solvent, Viscosity Controlling, Viscosity Decreasing Agent
VIEW ALL INGREDIENTS