Regenerist Hyaluronic + Peptide 24 Gel Face Moisturizer
Regenerist Hyaluronic + Peptide 24 Gel Face Moisturizer
Product Description
Product overview
A fragrance-free, lightweight gel moisturizer powered by Hyaluronic Acid, Niacinamide (Vitamin B3), and Palmitoyl Pentapeptide-4 (Matrixyl) that delivers 24-hour hydration. Clinically tested to plump, smooth, and restore skin's natural radiance without a greasy or sticky feel. Winner of the 2022 Allure Best of Beauty Award for Best Facial Moisturizer (Light).
24-Hour Hydration Lock
Patent-pending formula penetrates up to 10 layers deep into the skin's surface to trap moisture for a full 24 hours, outperforming luxury creams costing up to $400.
Texture & feel
SENSORY24-Hour Hydration Lock
Patent-pending formula penetrates up to 10 layers deep into the skin's surface to trap moisture for a full 24 hours, outperforming luxury creams costing up to $400.
Triple Active Complex
Combines Hyaluronic Acid, Niacinamide (Vitamin B3), and Palmitoyl Pentapeptide-4 (Matrixyl) to hydrate, strengthen the skin barrier, and support collagen production.
Ultralight Gel Formula
Absorbs quickly with zero sticky or tacky residue. Sits seamlessly under makeup and layered skincare products without pilling.
Award-Winning Performance
Winner of the 2022 Allure Best of Beauty Award for Best Facial Moisturizer (Light). Rated 4.5+ stars across Amazon, Walmart, and Target with thousands of reviews.
Safety & compatibility
SAFEContains no retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe during pregnancy and breastfeeding. Always consult your doctor.
Contains Polysorbate 20, a surfactant known to feed Malassezia yeast. Also contains Palmitoyl Pentapeptide-4 (palmitic acid ester). Not recommended for active fungal acne.
Main ingredients like Glycerin (0), Dimethicone (0–1), and Niacinamide (0) have very low pore-clogging potential. Suitable for acne-prone skin.
Clinically tested for safety. Free from parabens, mineral oil, phthalates, synthetic dyes, and added fragrances. Low irritation potential per independent analysis.
This gentle, pH-neutral gel pairs well with retinol (PM) and Vitamin C serums (AM). Niacinamide works synergistically with both actives.
Dimethicone and Dimethiconol provide occlusive moisture-sealing benefits. Generally well tolerated but some users sensitive to silicones may want to patch test.
Ingredient breakdown
INGREDIENTSSodium Hyaluronate (Hyaluronic Acid) <1%Proven
The sodium salt form of Hyaluronic Acid, a naturally occurring molecule in skin that can bind up to 1,000 times its weight in water. Plumps and hydrates skin from the surface, reducing the appearance of fine lines.
- Function: Humectant that attracts and retains water in the upper skin layers for sustained hydration
- Research: Proven to improve skin hydration, elasticity, and reduce wrinkle depth in numerous clinical studies
- Comedogenicity: 0 — will not clog pores
Niacinamide (Vitamin B3) ~2.7–4.1%Proven
A multi-functional skincare powerhouse. At this concentration, it strengthens the skin barrier by boosting ceramide production, evens skin tone, calms inflammation, and helps regulate sebum production.
- Barrier Repair: Increases ceramide synthesis for a stronger, healthier moisture barrier
- Anti-Aging: At 4–5%, proven to reduce fine lines and wrinkles
- Brightening: Fades dark spots and evens skin tone over time
- Anti-Inflammatory: Helps manage acne, rosacea, and atopic dermatitis
Palmitoyl Pentapeptide-4 (Matrixyl) TracePromising
A well-researched anti-aging peptide consisting of five amino acids (KTTKS sequence) attached to palmitic acid for better skin penetration. Created by Sederma and Procter & Gamble. Also known as a collagen pentapeptide since it is a subfragment of type I collagen.
- Collagen Support: Research shows it can stimulate collagen synthesis and reduce fine lines
- Skin Texture: Helps improve overall skin smoothness and firmness with consistent use
- Note: Peptides are effective at very low concentrations, typically 0.001–0.01%
Panthenol (Pro-Vitamin B5) <1%Proven
A humectant and skin-soothing agent that attracts and holds moisture. Converts to Vitamin B5 (pantothenic acid) in the skin, promoting lipid production for a healthier barrier. Also has anti-inflammatory and wound-healing properties.
- Moisturizing: Humectant that draws water to the skin and supports lipid barrier repair
- Soothing: Reduces irritation caused by other ingredients and environmental stressors
- Comedogenicity: 0 — non-comedogenic
Glycerin High (2nd in list)Proven
One of the most effective and well-researched humectants available. Listed second in the formula, indicating a significant concentration. Maintains skin lipids in a healthy liquid crystal state, protects against irritation, and enhances barrier function.
- Hydration: Effective from as low as 3%, with increased benefits at higher concentrations
- Barrier Support: Keeps skin lipids in a healthy state and protects against environmental irritation
- Comedogenicity: 0 — completely non-comedogenic
Dimethicone Moderate (3rd in list)Proven
A silicone-based emollient and occlusive that creates a breathable, protective layer over the skin. Locks in moisture, smooths the skin surface, and gives the gel its silky, non-greasy finish. Can temporarily fill in fine lines.
- Occlusive: Reduces transepidermal water loss (TEWL) to keep skin hydrated longer
- Finish: Provides the signature silky, non-sticky texture of this gel formula
- Comedogenicity: 0–1 — very low clogging potential
19 ingredients
Water, Glycerin, Dimethicone, Niacinamide, Sodium Hyaluronate, Palmitoyl Pentapeptide-4, Panthenol, Ethylhexylglycerin, Hydroxyacetophenone, C13-14 Isoparaffin, Dimethiconol, Polysorbate 20, Laureth-4, Laureth-7, Disodium EDTA, Polyacrylamide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aminomethyl Propanol, Phenoxyethanol
Where it fits in your routine
ROUTINEUse morning and night. Apply after serums and treatments but before sunscreen (AM). Can be your final step in PM routine. Layers beautifully under makeup.
How to use
HOW TO USECleanse
Wash your face with a gentle cleanser to remove dirt, oil, and makeup. Pat dry with a clean towel.
Treat (Optional)
Apply any targeted treatments like serums, eye creams, or spot treatments and allow them to absorb fully.
Apply Gel Moisturizer
Take a nickel-sized amount and smooth evenly over face and neck using gentle upward motions. The gel absorbs in 15–30 seconds with no sticky residue.
Protect (AM Only)
Follow with a broad-spectrum SPF 30+ sunscreen in the morning. This gel does not contain SPF. At night, this can be your final step.
Who is it for?
WHOPerfect for you if:
- You want lightweight hydration without a heavy or greasy feel
- You need a fragrance-free moisturizer for sensitive skin
- You want a moisturizer that layers well under makeup
- You have oily, combination, or normal skin that needs hydration without extra shine
- You want proven ingredients (HA, Niacinamide, Peptides) at a drugstore price
- You are pregnant or breastfeeding and need a safe daily moisturizer
Consider alternatives if:
- You have very dry skin and need a rich, heavy-duty cream (this may not be enough alone)
- You have active fungal acne — this contains Polysorbate 20 which feeds Malassezia
- You dislike silicone-based products (Dimethicone is a key ingredient)
- You need SPF protection in your moisturizer (this does not contain sunscreen)
- You prefer jar-free packaging for hygiene reasons (this comes in a jar)
Skin type compatibility
SKIN TYPESUltralight gel formula absorbs instantly without adding oil or shine. Niacinamide helps regulate sebum production. Perfect under makeup.
Provides hydration but may not be rich enough as a sole moisturizer in winter. Best layered with a heavier cream or facial oil on top for very dry skin.
Balances hydration across T-zone and cheeks without over-moisturizing oily areas. Lightweight enough for daily AM and PM use.
Fragrance-free and free of common irritants. Niacinamide and Panthenol actively soothe inflammation. Patch test recommended for very reactive skin.
Low comedogenic rating (1/5) and oil-free formula. Niacinamide helps reduce breakouts. However, not suitable for fungal acne due to Polysorbate 20.
Results timeline
MONTH 2–3Instant Hydration Boost
Skin feels immediately plumped, smooth, and hydrated. The gel absorbs quickly and leaves a comfortable dewy finish with no stickiness or residue.
95% noticed instant hydrationVisibly Healthier-Looking Skin
Skin begins to look more radiant and feel consistently softer. Niacinamide starts to strengthen the moisture barrier. Less dryness and tightness throughout the day.
80% saw visibly healthier skinSupple, Radiant Glow
Skin appears supple, plumped, and glowing. Fine lines look reduced from consistent hydration. Skin tone may look more even thanks to Niacinamide's brightening effect.
75% reported radiant, glowing skinLong-Term Barrier Strengthening
Continued Niacinamide and Peptide use helps strengthen the skin barrier and improve overall skin resilience. Less sensitivity to environmental stressors.
70% experienced stronger skin barrierRatings by platform
21K+ REVIEWSPros & cons
BALANCEDPraised
- Ultralight gel texture absorbs instantly — no sticky or greasy residue
- Fragrance-free formula ideal for sensitive skin
- Excellent under makeup — silky smooth base
- Proven ingredients: Hyaluronic Acid, Niacinamide, Matrixyl peptide
- Dermatologist tested and Allure Best of Beauty winner
- Affordable drugstore price with high-end performance claims
- Free of parabens, mineral oil, phthalates, dyes
- Noticeable hydration from first use that lasts all day
Criticized
- Jar packaging — less hygienic than pump or tube, can degrade active ingredients
- Not hydrating enough for very dry skin as a standalone moisturizer
- 1.7 oz jar runs out quickly with twice-daily use (~6 weeks)
- Contains silicones which some users prefer to avoid
- Not fungal acne safe (contains Polysorbate 20)
- May pill under certain sunscreens or makeup products
- Peptide concentration is likely very low (trace levels)
Budget-friendly alternatives (dupes)
DUPESVery similar lightweight gel texture with Hyaluronic Acid as the hero ingredient. Lacks Niacinamide and Peptides but provides comparable hydration at a lower price point. Also fragrance-free option available.
A fraction of the price with Hyaluronic Acid and amino acids. Creamier texture (not a gel), no Niacinamide or Peptides included. Excellent no-frills option for budget-conscious shoppers.
Contains Hyaluronic Acid, Niacinamide, and Ceramides for stronger barrier repair. Much richer cream texture — heavier than this gel. Better for dry skin but too heavy for oily types. No peptides.
Comparison with competitors
SIDE-BY-SIDEL'Oréal Revitalift HA Plumping Moisturizer
Storage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight. Close jar lid tightly after each use to prevent contamination and moisture loss.
Glass-look jar with screw-top lid. Consider using a clean spatula to maintain hygiene since jar packaging exposes product to air and fingers.
Yes — 1.7 oz (50ml) is under the 100ml TSA carry-on limit. A 0.5 oz travel size is also available.
Frequently asked questions
FAQYes. This moisturizer does not contain retinoids, salicylic acid, hydroquinone, chemical sunscreens, or any other ingredients commonly flagged during pregnancy. Hyaluronic Acid, Niacinamide, Glycerin, and Peptides are all considered safe for use during pregnancy and breastfeeding. As always, consult your OB-GYN or dermatologist before making changes to your skincare routine.
No. This product contains Polysorbate 20, which is a known feeding source for Malassezia yeast that causes fungal acne (pityrosporum folliculitis). It also contains Palmitoyl Pentapeptide-4, which has a fatty acid (palmitic acid) ester component. If you have active fungal acne, look for a moisturizer specifically verified as malassezia-safe.
Yes. This gel moisturizer has a gentle, pH-neutral formula that pairs well with most actives. Niacinamide is actually synergistic with retinol (reducing irritation) and Vitamin C (enhancing brightening). Apply water-based actives (Vitamin C, AHA/BHA) first, then layer this gel on top once absorbed. When using retinol, apply the gel before or after retinol in your PM routine for added moisture and buffer.
This gel moisturizer is best suited for oily, combination, and normal skin types due to its ultralight texture. It provides excellent hydration without heaviness or greasiness. For dry skin, it works well as a hydrating layer but may need to be paired with a richer cream or facial oil, especially in colder months. It is also a good choice for sensitive skin due to its fragrance-free, paraben-free formula.
Results are progressive: Day 1 delivers instant hydration and plumping. Within 2 weeks of consistent morning and night use, most users report visibly healthier-looking, softer skin. By 4 weeks, expect supple, more radiant skin with a noticeable glow. Long-term barrier strengthening from Niacinamide and Peptides becomes more apparent after 2–3 months of continuous use.
Apply this gel moisturizer after cleansing, toning, and any serums or treatments (like Vitamin C, retinol, or eye cream). In the morning, follow with sunscreen SPF 30+. At night, it can be your final step. The lightweight gel layers easily without pilling and sits well under makeup. The general rule: thin-to-thick, watery products first, then this gel, then heavier creams or oils if needed.
This moisturizer has a low comedogenic rating of 1 out of 5. Its key ingredients — Glycerin (0), Dimethicone (0–1), Niacinamide (0), Hyaluronic Acid (0), and Panthenol (0) — are all non-comedogenic or very low on the comedogenic scale. It is unlikely to clog pores for most people and is suitable for acne-prone skin. However, individual reactions can vary, so patch testing is always recommended.
The recommended Period After Opening (PAO) is 12 months. However, since this comes in a jar (not an airless pump), exposure to air and fingers can introduce bacteria. To extend shelf life, use a clean spatula to scoop product, close the lid tightly after each use, and store in a cool, dry place. With twice-daily use, the 1.7 oz jar typically lasts about 5–6 weeks.
Verdict: The Olay Regenerist Hyaluronic + Peptide 24 Gel Moisturizer delivers on its promise of lightweight, 24-hour hydration at a drugstore price. The triple-active formula (Hyaluronic Acid, Niacinamide at ~3%, and Matrixyl peptide) is well-supported by science for hydration, barrier repair, and anti-aging benefits. It excels for oily-to-combination skin types and those who want a non-greasy, fragrance-free moisturizer that layers beautifully under makeup. The main limitations are its jar packaging (less hygienic than a pump), the fact that it may not be moisturizing enough for very dry skin alone, and its unsuitability for fungal acne. For the price point, it punches well above its weight — a well-earned Allure Best of Beauty winner and a solid everyday moisturizer.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 3 |
Dimethicone
Skin Conditioning, Emollient, Antifoaming Agent, Skin Protecting
|
|
|
| 1 |
Niacinamide
Skin Conditioning, Hair Conditioning, Smoothing
|
Promotes Wound Healing
Redness
Irritation
Dark Spots
Pores
|
|
| 1 |
Sodium Hyaluronate
Skin Conditioning, Humectant
|
Promotes Wound Healing
Hydrating
|






