Regenerist Retinol 24 Night Facial Serum
Regenerist Retinol 24 Night Facial Serum
Product Description
Product overview
A lightweight, fast-absorbing night serum featuring a proprietary blend of Vitamin B3 (Niacinamide) + Retinol Complex that penetrates deep into skin's surface layers to deliver 24-hour hydration and visible anti-aging benefits with virtually no irritation.
Dual Retinoid Complex
Contains both Retinol and Retinyl Propionate for effective anti-aging with reduced irritation compared to pure retinol alone.
Texture & feel
SENSORYDual Retinoid Complex
Contains both Retinol and Retinyl Propionate for effective anti-aging with reduced irritation compared to pure retinol alone.
24-Hour Hydration
Glycerin and silicone-based formula locks in moisture for continuous hydration while you sleep.
Niacinamide Boost
Vitamin B3 works synergistically with retinol to brighten skin tone and strengthen the skin barrier.
Peptide Technology
Palmitoyl Pentapeptide-4 (Matrixyl) supports collagen production for firmer, more youthful-looking skin.
Safety & compatibility
SAFEContains Retinol and Retinyl Propionate. Avoid during pregnancy and breastfeeding as retinoids may pose risks to fetal development.
Contains Polysorbate 20 and C13-14 Isoparaffin which may feed Malassezia yeast. Those with pityrosporum folliculitis should avoid.
Silicone-based formula with a rating of 1/5. Unlikely to clog pores for most skin types.
Retinol increases photosensitivity. Always use SPF 30+ sunscreen the morning after application.
No added fragrances or essential oils. Suitable for sensitive noses and fragrance-sensitive skin.
Contains DMDM Hydantoin, a formaldehyde-releasing preservative. Most people tolerate it well, but some may be sensitive.
Ingredient breakdown
INGREDIENTSRetinol + Retinyl Propionate Undisclosed %Proven
A dual retinoid system combining pure Retinol with Retinyl Propionate (a vitamin A ester). This proprietary blend delivers anti-aging benefits while minimizing the irritation typically associated with retinol.
- Clinical Study: A P&G study found 0.3% Retinyl Propionate comparable to 0.02% tretinoin with better tolerability.
- Mechanism: Stimulates collagen production and accelerates cell turnover to reduce fine lines and wrinkles.
- Benefit: Visible improvements in wrinkles, texture, and dark spots within 28 days.
Niacinamide (Vitamin B3) Undisclosed %Proven
A versatile, well-researched ingredient that brightens skin, strengthens the moisture barrier, and works synergistically with retinol to reduce potential irritation.
- Research: Studies show niacinamide reduces hyperpigmentation and improves skin elasticity.
- Synergy: Helps buffer retinol irritation while enhancing overall anti-aging effects.
- Benefit: Reduces appearance of pores, evens skin tone, and controls oil production.
Palmitoyl Pentapeptide-4 (Matrixyl) Undisclosed %Promising
A signal peptide that stimulates collagen and elastin production. Known as Matrixyl, this peptide helps restore skin firmness and reduces the appearance of wrinkles.
- Clinical Data: Studies show visible reduction in wrinkle depth after 2-4 months of use.
- Mechanism: Signals skin cells to produce more collagen without irritation.
- Benefit: Supports firmer, more elastic skin over time.
Glycerin High concentrationProven
A powerful humectant that draws moisture into the skin. Positioned third in the ingredient list, indicating significant concentration for lasting hydration.
- Function: Attracts water from the environment and deeper skin layers to maintain hydration.
- Benefit: Provides the 24-hour moisturization claimed by the product.
19 ingredients
Water, Dimethicone, Glycerin, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Dimethiconol, C13-14 Isoparaffin, Laureth-4, Polysorbate 20, Laureth-7, Disodium EDTA, Dimethicone Crosspolymer, Polyacrylamide, Titanium Dioxide, Mica, DMDM Hydantoin, Iodopropynyl Butylcarbamate
Where it fits in your routine
ROUTINEUse at night only. Apply before moisturizer. Always follow with SPF 30+ the next morning.
How to use
HOW TO USECleanse Your Face
Start with clean, dry skin. Remove all makeup, dirt, and impurities with your favorite cleanser.
Apply the Serum
Dispense 2-3 drops onto fingertips. Gently massage evenly over face and neck, avoiding the eye area.
Follow with Moisturizer
Once absorbed (about 30 seconds), apply your night cream or moisturizer to seal in the benefits.
Morning SPF is Essential
The next morning, always apply a broad-spectrum SPF 30+ sunscreen. Retinol increases sun sensitivity.
Who is it for?
WHOPerfect for you if:
- You're new to retinol and want a gentler introduction
- You have fine lines, wrinkles, or uneven skin texture
- You want an affordable drugstore anti-aging solution
- You prefer fragrance-free skincare
- You have normal, combination, or oily skin
- You want visible results within 4 weeks
Consider alternatives if:
- You are pregnant or breastfeeding
- You have fungal acne (malassezia folliculitis)
- You're already using prescription retinoids (tretinoin)
- You have very dry or eczema-prone skin
- You're sensitive to formaldehyde-releasing preservatives
- You want a higher-strength retinol formula
Skin type compatibility
SKIN TYPESLightweight, silicone-based formula absorbs quickly without adding shine or greasiness. Helps control sebum production.
May not provide enough hydration alone. Layer with a rich moisturizer on top. Some users report dryness during initial weeks.
Balances well across different face zones. Non-greasy on T-zone while still hydrating drier cheeks.
Fragrance-free formula minimizes irritation. Niacinamide helps buffer retinol. Start slowly (every other night).
Low comedogenic rating (1/5). Retinol helps with cell turnover and pore refinement. Note: Not suitable for fungal acne.
Ideal target audience. Peptides and retinoids work synergistically to address wrinkles, firmness, and age spots.
Results timeline
3+ MONTHSImmediate Hydration
Skin feels smoother and more hydrated upon waking. The silicone-based formula leaves a silky finish overnight.
90% noticed softer skinTexture Improvement
Skin starts to feel smoother. Some may experience mild dryness or flaking as retinol accelerates cell turnover (this is normal).
70% noticed smoother textureVisible Brightness
Skin appears brighter and more even-toned. Fine lines begin to look less pronounced. Pores appear refined.
80% noticed brighter skinWrinkle Reduction
Noticeable reduction in fine lines and wrinkles. Dark spots begin to fade. Overall skin texture transformation.
85% noticed fewer wrinklesFull Anti-Aging Benefits
Maximum collagen-boosting effects. Firmer, more youthful-looking skin. Continued improvement with consistent use.
88% recommend continued useRatings by platform
6K+ REVIEWSPros & cons
BALANCEDPraised
- Gentle formula suitable for retinol beginners
- Fragrance-free with no added dyes
- Visible results within 4 weeks
- Lightweight, fast-absorbing texture
- Affordable drugstore price point
- Contains niacinamide and peptides as bonus actives
- 24-hour hydration claims backed by testing
- Widely available at most retailers
Criticized
- Small bottle size (1.3 oz) for the price
- Retinol concentration not disclosed
- Contains formaldehyde-releasing preservative (DMDM Hydantoin)
- Not suitable during pregnancy/breastfeeding
- Not fungal acne safe
- May be too light for very dry skin types
- Initial adjustment period may cause dryness
- Not cruelty-free (P&G tests on animals)
Budget-friendly alternatives (dupes)
DUPESSimilar retinol serum with added ceramides and licorice root. Better for acne-prone skin. Encapsulated retinol for slow release. Excellent barrier support.
Pure 0.5% retinol in squalane base. More potent but may cause more irritation. No peptides or niacinamide. Oil-based texture. Great for experienced retinol users.
OG drugstore retinol brand. Contains pure RoC retinol with mineral complex. May be more potent/irritating. Good track record for wrinkle reduction.
Uses patented Retinol SA for sustained action. Contains hyaluronic acid and glucose complex. Slightly faster visible results but contains fragrance.
Comparison with competitors
SIDE-BY-SIDERoC Retinol Correxion Serum
Storage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight. Keep cap tightly closed. No refrigeration required.
Opaque purple glass bottle with pump dispenser. Protects retinol from light degradation.
Yes, 1.3 oz (40ml) is under the 3.4 oz TSA limit for carry-on liquids.
Frequently asked questions
FAQNo, this product is NOT safe during pregnancy or breastfeeding. It contains Retinol and Retinyl Propionate, both vitamin A derivatives (retinoids). Retinoids are associated with potential risks to fetal development and should be avoided during pregnancy and nursing. Consult your healthcare provider for pregnancy-safe skincare alternatives like niacinamide, vitamin C, or azelaic acid.
No, this product is NOT fungal acne safe. It contains Polysorbate 20 and C13-14 Isoparaffin, which are potential triggers for Malassezia (the yeast that causes fungal acne/pityrosporum folliculitis). If you struggle with fungal acne, look for alternatives without these ingredients, such as products with simple silicone or glycerin-based formulas.
This serum already contains retinol, so avoid layering with other retinol products. For vitamin C: Use vitamin C in the morning and this retinol serum at night. For AHAs/BHAs: Alternate nights or use acids in the morning. Combining too many actives can cause irritation. Start slowly and listen to your skin. The niacinamide in this formula is safe to combine with most other ingredients.
This serum works best for oily, combination, and normal skin types. The lightweight, silicone-based formula absorbs quickly without leaving a greasy residue. Those with very dry skin may need to layer with a richer moisturizer. Mature skin will benefit most from the anti-aging ingredients. Sensitive skin can try it but should start with every-other-night application.
You may notice smoother, more hydrated skin immediately upon waking. Visible texture improvement typically appears within 1-2 weeks. Brightening and pore refinement become noticeable around weeks 3-4. For significant wrinkle reduction and anti-aging benefits, consistent use for 4-8 weeks is recommended. Maximum collagen benefits occur after 3+ months of regular use.
Use this serum at night only, after cleansing and toning but before moisturizer. The order is: Cleanser → Toner → This Serum → Eye Cream → Moisturizer. In the morning, skip this serum and apply SPF 30+ instead. Retinol increases sun sensitivity, making sunscreen essential the following day.
This serum has a low comedogenic rating of 1/5. The silicone-based formula (dimethicone) actually creates a breathable barrier that's unlikely to clog pores for most people. Retinol also helps with cell turnover, which can improve pore appearance. However, individual reactions vary, so patch test if you're prone to breakouts.
The product has a 12-month (12M) Period After Opening (PAO). Once opened, use within one year for best efficacy. Retinol can degrade over time when exposed to light and air, which is why Olay uses opaque packaging. Store in a cool, dry place away from direct sunlight. If the color or smell changes significantly, discontinue use.
Verdict: Olay Regenerist Retinol 24 Night Facial Serum is an excellent entry-level retinol for those new to vitamin A derivatives or with sensitive skin. The combination of retinol, retinyl propionate, niacinamide, and peptides delivers visible anti-aging results within 4 weeks with minimal irritation. While the undisclosed retinol concentration and formaldehyde-releasing preservative may concern some, the affordable price point, fragrance-free formula, and proven results make this a solid drugstore choice for tackling fine lines, wrinkles, and uneven texture. Not suitable for pregnancy, breastfeeding, or fungal acne sufferers.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 3 |
Dimethicone
Skin Conditioning, Emollient, Antifoaming Agent, Skin Protecting
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 9 |
Retinol
Skin Conditioning
|
Promotes Wound Healing
Dark Spots
Texture
Pores
|
|
| 0 |
Retinyl Propionate
Skin Conditioning
|
Promotes Wound Healing
Dark Spots
Texture
Pores
|






