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Reticor 0.025 Cream

Reticor 0.025 Cream

Product Description

Product overview

Made in Various INTERNATIONAL

A prescription-strength tretinoin 0.025% cream that accelerates skin cell turnover to treat acne, fade dark spots, smooth fine lines, and improve overall skin texture. The lowest concentration of tretinoin — ideal for beginners and sensitive skin types looking to start their retinoid journey.

Prescription Tretinoin Fragrance-Free Paraben-Free Silicone-Free Alcohol-Free Sulfate-Free Beginner-Friendly 0.025%
Pregnancy
No
Fungal Acne
No
Comedogenic
3/5
Type
Prescription
Size
15g / 0.53oz
Active
Tretinoin 0.025%
Brand
Derma XP
Manufacturer
Genero Pharma
Why it's different

Accelerates Cell Turnover

Tretinoin stimulates mitosis activity and increases turnover of follicular epithelial cells, shedding dead skin faster for a fresher complexion.

01

Texture & feel

SENSORY
Consistency
Rich cream
Scent
Fragrance-free
Absorption
1–2 minutes
Finish
Slightly dewy

Accelerates Cell Turnover

Tretinoin stimulates mitosis activity and increases turnover of follicular epithelial cells, shedding dead skin faster for a fresher complexion.

Treats Acne at the Source

Decreases cohesiveness of follicular epithelial cells to reduce microcomedo formation and extrude existing comedones, papules, and pustules.

Fades Hyperpigmentation

Promotes even melanin distribution and speeds up the replacement of pigmented cells with new, evenly toned skin over consistent use.

Boosts Collagen Production

Stimulates collagen synthesis in the dermis, reducing the appearance of fine lines, wrinkles, and photodamage over 8–12 weeks of consistent use.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding

Tretinoin is a retinoid classified as FDA Category X. It must NOT be used during pregnancy or breastfeeding due to the risk of birth defects. Discontinue use before planning conception.

Fungal Acne (Malassezia)

Contains Isopropyl Myristate and Polysorbate 60, which can feed Malassezia yeast. Not recommended for fungal acne-prone skin.

Sun Sensitivity

Tretinoin significantly increases photosensitivity. Always apply broad-spectrum SPF 30+ during the day and avoid prolonged sun exposure while using this product.

Retinization Period

Expect dryness, peeling, redness, and possible purging during the first 2–6 weeks. This is normal and typically subsides as the skin adjusts.

Fragrance-Free

Contains no added fragrances or essential oils, reducing the risk of irritation and contact dermatitis.

Paraben-Free & Sulfate-Free

Free from parabens, sulfates, and silicones. Uses benzoic acid and BHT as gentle preservative and antioxidant alternatives.

Drug Interactions

Avoid concurrent use with products containing sulfur, resorcinol, salicylic acid, or benzoyl peroxide unless directed by a physician, as these may cause excessive irritation.

Contraindications

Do not use if you have acute eczema, rosacea, sunburned skin, or known hypersensitivity to tretinoin or any ingredient in the formula.

03

Ingredient breakdown

INGREDIENTS

Tretinoin (All-Trans Retinoic Acid) 0.025%Gold Standard

The only FDA-approved topical retinoid for anti-aging. Tretinoin is the active form of Vitamin A — it requires no conversion by the skin, making it the most potent and effective retinoid available. It binds directly to retinoic acid receptors (RARs) in epidermal cells.

  • Mechanism: Decreases cohesiveness of follicular epithelial cells, reduces microcomedo formation, and accelerates cell turnover.
  • Acne: Clinically proven to reduce comedones, papules, and pustules in acne vulgaris.
  • Anti-Aging: A 1995 study found that 0.025% and 0.1% tretinoin produced similar photoaging improvement, but 0.025% caused significantly less irritation.
  • Collagen: Stimulates collagen I and III production, improving skin firmness and reducing fine lines over 8–24 weeks.
Start 2–3 times per week and gradually increase to nightly use. Always pair with SPF 30+ during the day. Expect mild peeling and redness during the first 2–6 weeks (retinization phase).

Panthenol (D-Panthenol / Pro-Vitamin B5) ~1–2%Soothing

A well-known humectant and skin soother that helps counterbalance the drying and irritating effects of tretinoin. Panthenol penetrates into the skin and converts to pantothenic acid (Vitamin B5).

  • Hydration: Attracts and retains moisture in the skin, helping to maintain barrier function during retinoid use.
  • Soothing: Reduces redness and irritation — rated 0 for both irritancy and comedogenicity.
  • Healing: Supports skin repair and wound healing, beneficial during the retinization period.
Excellent supporting ingredient to help minimize tretinoin-related dryness and irritation.

Cetearyl Alcohol & Stearyl AlcoholEmollient Base

Fatty alcohols that form the cream's smooth, rich base. Despite the name, these are non-drying and non-irritating — completely different from denatured alcohol. They provide emollient properties and stabilize the emulsion.

  • Emollient: Softens and smooths the skin, providing a comfortable cream texture.
  • Safety: Cetearyl alcohol has an irritancy rating of 1 and comedogenicity rating of 2 — generally well-tolerated.
  • Function: Acts as a viscosity controller and emulsion stabilizer at typical levels of 2–3%.

Isopropyl MyristateEmollient

A lightweight, fast-spreading emollient that helps tretinoin penetrate the skin more effectively. Enhances the delivery of the active ingredient into the epidermis.

  • Penetration: Helps tretinoin absorb into the skin for better efficacy.
  • Texture: Provides a non-greasy, smooth application feel.
Isopropyl Myristate has a high comedogenicity rating (up to 5) and can feed Malassezia yeast. Not ideal for very acne-prone or fungal acne-prone skin types.

BHT (Butylated Hydroxytoluene)Antioxidant

A synthetic antioxidant that protects the cream formula — and especially the tretinoin — from oxidation and degradation. Used at very low concentrations (typically 0.01–0.1%).

  • Stability: Prevents tretinoin from breaking down due to air and light exposure, extending product shelf life.
  • Safety: The CIR concluded that BHT at cosmetic concentrations does not penetrate deep enough to be absorbed systemically and is safe for topical use.

12 ingredients

Tretinoin 0.025%, Cetearyl Alcohol, Stearyl Alcohol, Isopropyl Myristate, Polysorbate 60, Sorbitan Stearate, BHT (Butylated Hydroxytoluene), Benzoic Acid, Disodium EDTA, Panthenol, Purified Water, Sodium Hydroxide

FREE FROM: Fragrances, Essential Oils, Parabens, Sulfates, Silicones, Harsh Alcohols (Denatured Alcohol), Common Allergens, Dyes/Colorants
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Wait 20–30 min
3
Reticor 0.025
4
Wait 10–15 min
5
Moisturizer
6
SPF (AM only)

Apply at night only. Wait 20–30 minutes after cleansing on dry skin for best results. Use the "sandwich method" (moisturizer before and after) if irritation occurs. Always follow with SPF 30+ the next morning.

05

How to use

HOW TO USE
1

Cleanse Gently

Wash your face with a mild, non-medicated cleanser. Pat dry completely with a clean towel. Avoid abrasive soaps or scrubs.

2

Wait 20–30 Minutes

Allow skin to fully dry. Applying tretinoin to damp skin increases irritation and sensitivity. Your skin should feel completely dry to the touch.

3

Apply a Pea-Sized Amount

Squeeze a pea-sized amount onto your fingertip. Dot it evenly across forehead, cheeks, and chin. Gently spread a thin film over the entire affected area. Avoid the eye area, nostrils, mouth corners, and mucous membranes.

4

Moisturize After

Wait 10–15 minutes for the tretinoin to absorb, then follow with a gentle, non-comedogenic moisturizer to prevent excessive dryness and support the skin barrier.

5

Start Slowly, Build Tolerance

Begin with 2–3 times per week for the first 2–4 weeks, then gradually increase frequency to every other night, and eventually nightly as tolerated. If excessive dryness or peeling occurs, reduce frequency.

06

Who is it for?

WHO

Perfect for you if:

  • You have mild to moderate acne (comedones, papules, pustules)
  • You want to start tretinoin for the first time at the gentlest strength
  • You have early signs of photoaging (fine lines, sun spots, uneven tone)
  • You want prescription-strength retinoid without jumping to 0.05% or 0.1%
  • You have post-acne hyperpigmentation or dark spots to fade
  • You are looking for a fragrance-free, minimal-ingredient retinoid formula

Consider alternatives if:

  • You are pregnant, planning pregnancy, or breastfeeding
  • You have fungal acne (malassezia folliculitis) — contains Isopropyl Myristate and Polysorbate 60
  • You have active eczema, rosacea, or severely sunburned skin
  • You are allergic to tretinoin or any ingredient in the formula
  • You need a higher strength for stubborn acne (consider 0.05% or 0.1% after building tolerance)
  • You cannot commit to daily sunscreen use
07

Skin type compatibility

SKIN TYPES
Oily Skin
Good

Tretinoin helps regulate sebum production. However, the cream base with Isopropyl Myristate may feel heavy on very oily skin. A gel formulation may be preferred.

Dry Skin
Excellent

The rich cream base with fatty alcohols and Panthenol provides moisture and comfort. The 0.025% strength minimizes dryness. Ideal formulation for dry skin types.

Combination Skin
Good

Works well across different face zones. Apply a thinner layer on oily T-zone and slightly more on drier areas. The 0.025% concentration is gentle enough for mixed skin needs.

Sensitive Skin
Good

The lowest available tretinoin concentration, making it the best starting option for sensitive skin. Use the sandwich method and start at 2x/week. Patch test recommended.

Acne-Prone Skin
Moderate

Tretinoin is clinically proven for acne, but the cream base contains Isopropyl Myristate (comedogenic rating up to 5). Expect initial purging. A gel formulation may be better for very acne-prone skin.

08

Results timeline

MONTH 3–6
Week 1–2

Retinization Phase Begins

Mild dryness, tightness, and slight peeling as the skin adjusts to tretinoin. Some users experience a warm or tingling sensation upon application. This is completely normal.

80% experience some dryness
Week 2–6

Purging Period

Existing microcomedones are pushed to the surface faster, potentially causing temporary breakouts. Skin peeling and redness may peak during this phase before gradually subsiding.

60% notice purging
Week 6–8

Skin Tone Improvement

Skin tone begins to even out as accelerated cell turnover replaces pigmented and damaged cells. Pores appear smaller and skin texture starts to feel smoother.

70% see improvement in tone
Week 8–12

Visible Transformation

Significant reduction in acne lesions, visible fading of dark spots, and smoother skin texture. Fine lines appear diminished. Most users report clear, visible results by this stage.

85% see significant improvement
Month 3–6

Optimal Results

Full anti-aging and acne benefits are established. Collagen production increases noticeably, skin appears firmer and more youthful. Hyperpigmentation fades substantially. Results continue to improve with consistent long-term use.

90% report satisfaction
09

Ratings by platform

694+ REVIEWS
Drugs.com (Tretinoin Topical)
7.7/10
Rating
494+
Reviews
Main complaint: Initial purging phase and excessive dryness/peeling in the first few weeks
SkinSort Community
4.2
Rating
38+
Routines
Main complaint: Small tube size (15g) runs out quickly with daily use
Online Pharmacies
4.5
Rating
200+
Reviews
Main complaint: Can be difficult to source outside Indonesia; requires prescription in many countries
Reddit r/tretinoin
4.3
Sentiment
1,000+
Discussions
Main complaint: Cream base feels heavy for oily skin; many prefer the gel version for acne
10

Pros & cons

BALANCED

Praised

  • Gold standard prescription-strength retinoid (all-trans retinoic acid)
  • Lowest concentration — ideal for beginners and sensitive skin
  • Fragrance-free, paraben-free, silicone-free minimal formula (only 12 ingredients)
  • Contains Panthenol (Pro-Vitamin B5) to soothe and hydrate
  • Clinically proven anti-aging and acne-fighting efficacy
  • Affordable compared to Western branded tretinoin (Retin-A)
  • Rich cream base provides comfort for dry and normal skin types

Criticized

  • Contains Isopropyl Myristate (highly comedogenic, not fungal acne safe)
  • Contains Polysorbate 60 (feeds Malassezia yeast)
  • Small tube size (15g) — runs out in approximately 4–6 weeks
  • Initial purging, peeling, and redness during retinization phase
  • Cream base may feel too heavy for oily skin types
  • Short PAO of only 35 days after opening
  • Not available OTC in most countries — requires prescription
  • Absolutely not safe during pregnancy or breastfeeding
11

Budget-friendly alternatives (dupes)

DUPES
90% Match
Vitacid Cream 0.025%
$4–6
Budget Pick

Another Indonesian tretinoin 0.025% cream with a nearly identical formulation. Same active ingredient at the same concentration. Slightly different inactive ingredient base but effectively interchangeable with Reticor.

85% Match
A-Ret Tretinoin Gel 0.025%
$3–5
Budget Pick

Indian-made tretinoin 0.025% cream widely available internationally. Very affordable and equally effective. Slightly different cream base formulation but delivers the same active ingredient.

70% Match
Adapalene Gel 0.1%
$13–15
Similar Effect

Available OTC without prescription. Uses adapalene instead of tretinoin — a third-generation retinoid that is less irritating but also less potent for anti-aging. Comparable acne efficacy to tretinoin 0.025%. Better tolerated by sensitive skin.

55% Match
Retinol 0.5% in Squalane
$6–8
Budget Pick

OTC retinol (not tretinoin). Requires conversion by the skin to retinoic acid, making it significantly weaker. Best for retinoid beginners who cannot access prescription tretinoin or want minimal irritation. Will not match tretinoin's proven results.

12

Comparison with competitors

SIDE-BY-SIDE
Retin-A® Cream (Tretinoin) 0.1%

Retin-A 0.025% Cream (Bausch Health)

Active Ingredient Tretinoin 0.025%
Size 20g / 45g
Formulation Cream
Fragrance-Free Yes
Fungal Acne Safe No
Total Ingredients 9
Origin Canada / USA
Vitacid Cream 0.025%
Active Ingredient Tretinoin 0.025%
Size 15g
Formulation Cream
Fragrance-Free Yes
Fungal Acne Safe No
Total Ingredients 12
Origin Indonesia
Adapalene Gel 0.1%
Active Ingredient Adapalene 0.1%
Size 15g / 45g
Formulation Gel
Fragrance-Free Yes
Fungal Acne Safe Yes
Total Ingredients 10
Origin France / USA
13

Storage & shelf life

1 MONTHS
Period After Opening (PAO)

35 days after opening (approximately 1 month). Use promptly once opened as tretinoin degrades with air and light exposure.

Storage

Store below 27°C (80°F) in a cool, dry place away from direct sunlight and heat. Do not freeze. Keep the tube tightly closed after each use.

Packaging

Aluminum tube with screw cap. The opaque tube protects tretinoin from light degradation.

Travel Friendly

Yes, 15g tube is well under the 100ml carry-on liquid limit. Keep in a cool pouch during travel to maintain stability.

13

Frequently asked questions

FAQ

No. Reticor contains tretinoin, a retinoid classified as FDA Pregnancy Category X. Retinoids have been associated with birth defects and must NOT be used during pregnancy or breastfeeding. Discontinue use at least one month before planning conception and consult your healthcare provider for safe alternatives such as azelaic acid.

No. Reticor contains Isopropyl Myristate and Polysorbate 60, both of which can feed Malassezia yeast and potentially worsen fungal acne. If you have malassezia folliculitis, consider a tretinoin gel formulation or adapalene gel (Differin), which typically have fungal acne-safe ingredients.

Use caution when combining tretinoin with other active ingredients. Avoid using AHA (glycolic acid, lactic acid), BHA (salicylic acid), benzoyl peroxide, or vitamin C on the same night as tretinoin, as this can cause excessive irritation. You can alternate nights or use vitamin C in the morning and tretinoin at night. Do not layer additional retinol products over tretinoin — they serve the same purpose and will only increase irritation without added benefit. Always consult your dermatologist before combining prescription actives.

The cream formulation is best suited for dry to normal skin types, as the fatty alcohol and emollient base provides moisture and comfort. It is also an excellent starting strength for sensitive skin due to its low 0.025% concentration. Those with oily or very acne-prone skin may prefer a gel formulation instead, as the cream base contains comedogenic ingredients like Isopropyl Myristate.

Most users begin to see noticeable improvement in skin texture and acne reduction within 6–8 weeks of consistent use. Significant results for fine lines, dark spots, and overall skin clarity typically appear at 8–12 weeks. Full anti-aging benefits with collagen improvement are generally seen after 3–6 months of continued nightly use. Patience is essential — the purging phase (weeks 2–6) is temporary and part of the normal process.

Apply Reticor at night only, after cleansing and waiting 20–30 minutes for the skin to dry completely. Apply a pea-sized amount to the entire face, then wait 10–15 minutes before applying moisturizer. In the morning, follow your regular routine and always apply broad-spectrum SPF 30+. If irritation occurs, try the "sandwich method" — apply moisturizer first, then tretinoin, then moisturizer again.

The cream has a moderate comedogenic risk (rated 3/5) primarily due to Isopropyl Myristate, which has a comedogenicity rating of up to 5 on its own. However, tretinoin itself is comedolytic — it actively unclogs pores and prevents new comedones from forming. For most users, the acne-fighting benefit of tretinoin outweighs the comedogenic risk of the base ingredients. If you are very acne-prone, a gel formulation may be a better choice.

Reticor should be used within 35 days after opening. Tretinoin is sensitive to air, light, and heat — it degrades when exposed to these elements, reducing its effectiveness. Always keep the tube tightly sealed, store it below 27°C (80°F), and away from direct sunlight. The 15g tube typically lasts 4–6 weeks when used at the recommended pea-sized amount per application.

— Skincarisma verdict
4.2 / 5 ★★★★☆

Verdict: Reticor 0.025% Cream is an affordable, no-frills prescription tretinoin that delivers the gold standard of retinoid treatment at the gentlest available strength. With only 12 ingredients and a fragrance-free formula enriched with Panthenol, it is an excellent entry point for anyone starting their tretinoin journey — particularly those with dry to normal skin who want to address acne, hyperpigmentation, or early signs of aging. The main drawbacks are its comedogenic cream base (not ideal for very oily or fungal acne-prone skin), the short 35-day PAO, and the small 15g tube size. For the price point and proven efficacy of tretinoin, Reticor offers outstanding value — especially compared to branded options like Retin-A that cost 10–20 times more for the identical active ingredient.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 1 ingredient(s):
Tretinoin
brightening Brightening from 1 ingredient(s):
Tretinoin
wound Promotes Wound Healing from 1 ingredient(s):
Tretinoin
ache Ache-fighting from 1 ingredient(s):
Tretinoin
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
oily-skin Oily/Acne-Prone Skin
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
100%

Product ingredient list

Showing first 5 of 1 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
0 Unknown
Tretinoin
Skin Conditioning
brightening Brightening
ache Ache-fighting
anti-aging Anti-Aging
Promotes Wound Healing
Dark Spots
Texture
Pores