SD Advanced ™ PLUS Intensive Moisturizer For Wrinkles & Stretch Marks
SD Advanced ™ PLUS Intensive Moisturizer For Wrinkles & Stretch Marks
Product Description
Product overview
A peptide-rich intensive moisturizing concentrate that visibly reduces wrinkles and stretch marks while delivering up to 100 hours of continuous hydration. Powered by StriVectin's patented NIA-114 technology and an AI-designed Alpha-3 Peptide, this breakthrough formula targets skin's natural collagen, elastin, and hyaluronic acid for plumper, smoother, more youthful-looking skin in as little as one week.
AI-Designed Alpha-3 Peptide
Exclusive peptide engineered to target skin's natural collagen, elastin, and hyaluronic acid simultaneously for multi-dimensional anti-aging benefits.
Texture & feel
SENSORYAI-Designed Alpha-3 Peptide
Exclusive peptide engineered to target skin's natural collagen, elastin, and hyaluronic acid simultaneously for multi-dimensional anti-aging benefits.
Patented NIA-114 Technology
StriVectin's proprietary optimized form of Vitamin B3 (niacin) that strengthens the skin barrier and supercharges the performance of other active ingredients.
Triple Peptide Complex
Copper Tripeptide, Cranberry Biopeptides, and Alpha-3 Peptide work together to target 10 types of collagen for visible wrinkle and stretch mark reduction.
100-Hour Hydration
Combines hyaluronic acid with tucuma, cupuacu, and murumuru butters to deliver sustained moisture that lasts up to 100 hours per application.
Botanical Butters Blend
Shea butter, murumuru seed butter, and cupuacu seed butter deeply nourish the skin while locking in moisture and improving skin texture.
Sea Salt Ferment Technology
Proprietary Bacillus/Sea Salt Ferment Filtrate supports skin's water channels for lasting hydration and visibly diminishes lines and wrinkles.
Safety & compatibility
SAFEContains lactic acid (AHA) and fragrance. No retinoids, hydroquinone, or salicylic acid. Consult your physician before use during pregnancy or nursing.
Not fungal acne safe. Contains Polysorbate 60, Ethylhexyl Stearate, Sorbitan Stearate, and Sorbitan Isostearate which can feed Malassezia yeast.
Does not contain retinol, retinyl palmitate, or any retinoid derivatives. Safe to use alongside separate retinol products in an alternating routine.
Free of parabens, sulfates (SLS & SLES), phthalates, formaldehyde, mineral oil, oxybenzone, coal tar, hydroquinone, triclocarban, and triclosan.
PETA certified cruelty-free. StriVectin does not test on animals at any stage of product development.
Parfum/Fragrance is included in the formula. Those with very sensitive or reactive skin should patch test first. Some users report a mild chemical-like scent.
Contains lactic acid at a low concentration for gentle exfoliation. Use sunscreen during daytime as AHAs increase sun sensitivity.
Independently clinically tested on 43 subjects. 100% agreed skin felt smoother, softer, and more supple after 4 weeks of twice-daily use.
Ingredient breakdown
INGREDIENTSAlpha-3 Peptide (Pentapeptide-84 Amide Acetate)Patented
StriVectin's exclusive AI-designed peptide that simultaneously targets three of skin's natural building blocks: collagen, elastin, and hyaluronic acid. This next-generation peptide provides 30% more collagen-boosting power than previous StriVectin formulations.
- Mechanism: Signals skin cells to increase production of collagen, elastin, and hyaluronic acid simultaneously
- Clinical data: In a study of 43 subjects, 93% agreed their skin looked dramatically better after 4 weeks
- Unique feature: AI-generated peptide sequence optimized for multi-target activity
NIA-114 (Myristyl Nicotinate)Patented
StriVectin's proprietary, patented form of Vitamin B3 (niacin), developed over 35 years of biomedical research. It strengthens the skin's moisture barrier more effectively than standard niacinamide and supercharges the performance of other active ingredients in the formula.
- Research: Over 35 years of scientific development by Drs. Myron and Elaine Jacobson
- Mechanism: Targets NAD (nicotinamide adenine dinucleotide) to strengthen the skin barrier at a cellular level
- Benefit: Helps other actives penetrate and perform better while protecting against environmental stressors
Copper Tripeptide-1Proven
A well-researched signal peptide that promotes collagen synthesis and wound healing. In this formula, it targets 10 types of collagen to visibly reduce wrinkles and stretch marks.
- Evidence: Multiple peer-reviewed studies confirm collagen-stimulating and wound-healing properties
- Function: Targets 10 types of collagen including Types I, III, IV, and VII
- Additional: Anti-inflammatory properties help calm skin and reduce redness
Cranberry Biopeptides (Vaccinium Macrocarpon Fruit Extract)Promising
Plant-derived peptides extracted from cranberry fruit that help support natural collagen production to visibly smooth skin and improve texture. New addition to the upgraded formula.
- Source: Derived from Vaccinium Macrocarpon (cranberry) fruit
- Function: Supports natural collagen synthesis for improved skin firmness
- Benefit: Visibly smooths skin texture when used consistently
Hyaluronic Acid ComplexProven
A multi-molecular weight hyaluronic acid system including Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate Crosspolymer for both surface and deep skin hydration.
- Hydrolyzed HA: Smaller molecules penetrate deeper into the skin for plumping from within
- Crosspolymer HA: Forms a moisture-locking film on the skin surface for long-lasting hydration
- Combined: Contributes to the up to 100-hour continuous moisture claim
Palmitoyl Tripeptide-38 (Matrixyl synthe'6)Proven
A synthetic peptide that stimulates the synthesis of six major constituents of the skin matrix including collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5.
- Evidence: In vitro studies show significant stimulation of extracellular matrix components
- Synergy: Works alongside Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 for enhanced anti-aging effects
Botanical Butter TrioEmollients
Three rich plant butters — Cupuacu Seed Butter, Murumuru Seed Butter, and Shea Butter — that deeply nourish, soften, and protect the skin barrier while delivering sustained moisture.
- Cupuacu (Theobroma Grandiflorum): Rich in phytosterols, absorbs water up to 440% of its weight
- Murumuru (Astrocaryum Murumuru): High in lauric and myristic acids for deep moisturization
- Shea (Butyrospermum Parkii): Contains vitamins A, E, and F with anti-inflammatory properties
ResveratrolProven
A powerful polyphenol antioxidant found in grapes, berries, and red wine. Protects skin from free radical damage and environmental stressors while supporting collagen production.
- Evidence: Well-documented antioxidant with anti-inflammatory and collagen-protective effects
- Benefit: Helps prevent premature aging caused by UV and pollution exposure
62 ingredients
Water/Aqua/Eau, Glycerin, Pentaerythritol Tetraisostearate, Neopentyl Glycol Diheptanoate, Trimethylolpropane Tricaprylate/Tricaprate, Propanediol, Myristyl Nicotinate, Cetearyl Alcohol, Butylene Glycol, Stearyl Dimethicone, Glyceryl Stearate, Theobroma Grandiflorum Seed Butter, Dimethicone, Sorbitan Stearate, Stearoxy Dimethicone, Butyrospermum Parkii (Shea) Butter, Astrocaryum Murumuru Seed Butter, Vaccinium Macrocarpon (Cranberry) Fruit Extract, Evodia Rutaecarpa Fruit Extract, Helianthus Annuus (Sunflower) Extract, Oryza Sativa (Rice) Bran Extract, Astrocaryum Vulgare Kernel Oil, Nymphaea Alba Flower Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Hydrolyzed Hyaluronic Acid, Pentaclethra Macroloba Seed Oil/Behenic Acid/Aminopropanediol Amides/Esters, Pentapeptide-84 Amide Acetate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Nicotiana Benthamiana Hexapeptide-40 sh-Oligopeptide-1, Copper Tripeptide-1, Phaseolus Lunatus (Green Bean) Seed Extract, Sodium Hyaluronate Crosspolymer, Aloe Barbadensis Leaf Juice, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Zingiber Officinale (Ginger) Root Extract, Bacillus/Sea Salt Ferment Filtrate, Copper Lysinate/Prolinate, Resveratrol, Panthenol, PEG-40 Stearate, Saccharide Isomerate, Isohexadecane, Dimethicone/Vinyl Dimethicone Crosspolymer, Ceteareth-20, Bisabolol, Caprylhydroxamic Acid, Fragrance/Parfum, Ethylhexyl Stearate, Polysorbate 60, Disodium EDTA, Xanthan Gum, Adenosine, Sorbitan Isostearate, Aminomethyl Propanol, Dicaprylyl Ether, Methylglucoside Phosphate, Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate, Sodium Isostearate, Tocopherol, Hydroxypropyl Cyclodextrin, Lactic Acid, Caprylyl Glycol, Ethanol, Sodium Citrate, Cetyl Hydroxyethylcellulose, 1,2-Hexanediol, Rutin, Citric Acid, Dipotassium Phosphate, Titanium Dioxide (CI 77891), Mica (CI 77019), Iron Oxides (CI 77491)
Where it fits in your routine
ROUTINEApply after serums as your moisturizing step, both AM & PM. StriVectin recommends the order: Cleanser, Mask, Toner, Eye Cream, Serum, Moisturizer, Neck Cream, Primer.
How to use
HOW TO USECleanse & Prep
Start with a clean, dry face. Apply any toner, eye cream, or serum first and let them absorb.
Apply to Face (For Wrinkles)
Take a small amount and apply all over clean face, avoiding the eye area. Gently massage into wrinkle-prone areas using upward and outward motions in the morning and evening.
Apply to Body (For Stretch Marks)
Use morning and evening on clean skin, massaging into targeted stretch mark areas on the body. A little goes a long way — the concentrate formula is highly potent.
Pro Tip
Press product over expression lines to soften their appearance before applying makeup. Follow with sunscreen in the morning, as the formula contains lactic acid (AHA).
Who is it for?
WHOPerfect for you if:
- You want to target fine lines, wrinkles, and expression lines
- You have stretch marks on face or body you'd like to reduce
- You need intense, long-lasting hydration for dry or dehydrated skin
- You want a peptide-rich anti-aging cream without retinol
- You're looking for a moisturizer that pairs well with retinol treatments
- You want clinically tested results within 1–4 weeks
- You prefer a multi-use product for both face and body
Consider alternatives if:
- You have fungal acne (Malassezia) — formula contains problematic esters and polysorbates
- You need a completely fragrance-free product for very sensitive skin
- You prefer an ultra-lightweight or gel-based moisturizer for oily skin
- You're on a tight budget — this is a premium-priced product ($85–$149)
- You want an oil-free formula — contains multiple butters and oils
- You dislike any scent at all in your skincare products
Skin type compatibility
SKIN TYPESThis product excels on dry skin. The rich butter blend and 100-hour hydration claim make it ideal for deeply nourishing parched, dehydrated complexions.
Absorbs well without feeling heavy, provides balanced hydration and powerful anti-aging benefits without over-moisturizing normal skin.
Works well overall, but some users with combination skin may find the T-zone slightly shiny. Best applied more sparingly on oilier areas.
Rich cream formula may feel too heavy for oily skin types. Some users report a shiny finish during the day. Consider using only at night if you have oily skin.
Generally well-tolerated thanks to barrier-strengthening NIA-114, but contains fragrance and lactic acid. Patch test recommended for highly reactive skin.
Ideal for mature skin. The multi-peptide complex, collagen-boosting technology, and rich moisture make this a standout for aging concerns.
Results timeline
WEEK 8+Immediate Hydration & Softness
Skin feels instantly smoother, softer, and more supple. The rich cream provides immediate comfort and a dewy, nourished feel. Some users notice visibly plumper skin after the first application.
100% noticed immediate hydrationVisible Reduction in Fine Lines
The appearance of fine lines and wrinkles begins to visibly reduce. Skin texture feels smoother and more refined. The NIA-114 technology starts strengthening the moisture barrier noticeably.
Clinically observed wrinkle reduction after 1 weekStretch Mark Improvement Begins
Visible improvement in the look of stretch mark texture and intensity. Skin appears more even-toned and resilient. Fine lines continue to soften and become less noticeable.
Visible stretch mark texture improvement at 2 weeksClinically Proven Stretch Mark Improvement
Clinically proven to improve the look of stretch marks based on expert grading evaluation. 100% of subjects agreed skin felt smoother, softer, and more supple. 93% said their skin looks dramatically better.
93% agreed skin looks dramatically betterTransformative Long-Term Results
Continued improvement in elasticity, firmness, and overall skin radiance. 95% of subjects said they would switch to this as their regular moisturizer. Maximum collagen-boosting benefits are realized with consistent use.
95% would switch to this as their regular moisturizerRatings by platform
2K+ REVIEWSPros & cons
BALANCEDPraised
- Visible wrinkle reduction within 1–2 weeks of consistent use
- Exceptional long-lasting hydration (up to 100 hours claimed)
- Dual-use formula works on both face wrinkles and body stretch marks
- Concentrated formula — a little goes a long way
- Pairs well with retinol products without irritation
- Clinically tested with impressive satisfaction rates (100% smoother skin)
- Paraben-free, cruelty-free, and free of many common irritants
- Rich texture absorbs without feeling greasy
Criticized
- Premium pricing ($85 for 2 oz, $149 for 4 oz) may be prohibitive
- Mixed reactions to scent — some find it chemical-like or medicinal
- Can cause slight pilling when layered under certain products
- May be too rich for oily skin, leaving a shiny finish during the day
- Contains fragrance, which can irritate very sensitive skin
- Not fungal acne (Malassezia) safe
- Rare reports of mild redness or irritation on very sensitive cheeks
- Small tube sizes don't last long with twice-daily use on face and body
Budget-friendly alternatives (dupes)
DUPESContains peptides and hyaluronic acid like StriVectin, but lacks the proprietary NIA-114 technology, copper tripeptide complex, and botanical butters. Simpler peptide blend with ceramides instead. Fragrance-free option for sensitive skin.
Shares niacinamide and peptide-based approach with hyaluronic acid. Good anti-aging moisturizer at a fraction of the price. Missing the specialized stretch mark treatment, copper peptide, and patented Alpha-3 Peptide technology.
Basic peptide-based moisturizer with a much simpler formula. Contains Matrixyl 3000 peptide complex and shea butter. Lacks the multi-peptide complexity, NIA-114, stretch mark targeting, and long-lasting hydration of StriVectin.
StriVectin's own alternative with similar NIA-114 technology and peptide approach but in a lighter gel-cream hybrid texture. Focuses more on plumping than stretch mark treatment. Slightly less expensive but different texture profile.
Comparison with competitors
SIDE-BY-SIDEStriVectin SD Advanced PLUS
Storage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight. Keep tightly closed when not in use.
Squeeze tube with screw cap. Sturdy packaging that protects the concentrated formula from air exposure.
Yes — the 2 oz size is under 100ml / 3.4 oz TSA limit, making it carry-on compliant for air travel.
Frequently asked questions
FAQUse with caution. This product does not contain retinoids, salicylic acid, or hydroquinone, which are the most commonly flagged ingredients during pregnancy. However, it does contain lactic acid (a mild AHA) and fragrance (Parfum). While lactic acid at low concentrations in topical products is generally considered low-risk, it is always best to consult your physician or dermatologist before using any new skincare product during pregnancy or while breastfeeding.
No, this product is not fungal acne safe. The formula contains several ingredients that can feed Malassezia yeast, including Polysorbate 60, Ethylhexyl Stearate, Sorbitan Stearate, and Sorbitan Isostearate. If you are prone to fungal acne (pityrosporum folliculitis), you should avoid this product and look for a Malassezia-safe moisturizer alternative instead.
Yes, this product can be used alongside retinol, vitamin C, and other actives. Since it contains a low concentration of lactic acid (AHA), be cautious when layering it with additional strong exfoliating acids (AHA/BHA) to avoid over-exfoliation. Many users report it works exceptionally well as a companion to prescription retinol, helping to prevent peeling and dryness. If combining with vitamin C, apply vitamin C serum first, then this moisturizer on top. When using with retinol, you can apply this either before or after retinol depending on your skin's tolerance.
This product is best suited for dry, normal, and mature skin types. Its rich, concentrated formula provides deep, long-lasting hydration that dry and aging skin will love. Combination skin types can also benefit, especially during colder months or when dealing with dehydration. Oily skin types may find the texture too rich for daytime use but can use it as a night cream. Sephora lists it as suitable for Normal, Dry, Combination, and Oily skin types.
Based on clinical studies: you can expect visible reduction in fine lines and wrinkles within 1 week. Stretch mark texture and intensity show visible improvement at 2 weeks. After 4 weeks of twice-daily use, clinically proven improvement in stretch marks was observed. Many users report noticing softer, smoother skin after the very first application. For maximum results, StriVectin recommends consistent twice-daily use for at least 4–8 weeks.
Apply this product as your moisturizer step. StriVectin recommends the following order: Cleanser, Mask, Toner, Eye Cream, Serum, Moisturizer (this product), Neck Cream, Primer/Sunscreen. Apply after any water-based serums and before heavier occlusives or sunscreen. Use on clean face in the morning and evening, avoiding the eye area. For stretch marks on the body, apply directly to targeted areas after cleansing.
This product has a moderate comedogenic rating of 2 out of 5. It contains some potentially comedogenic ingredients like shea butter (comedogenic rating 0–2) and other plant butters, but also includes many non-comedogenic humectants like glycerin and hyaluronic acid. Most users report no breakouts, but if you are very acne-prone, it's wise to patch test first. The product is not specifically marketed as non-comedogenic or oil-free.
The product has a Period After Opening (PAO) of approximately 12 months. With twice-daily use on the face only, the 2 oz tube typically lasts 6–8 weeks, and the 4 oz tube lasts approximately 12–16 weeks. If you're also using it on stretch marks on the body, it will be used up more quickly. The concentrated formula means you only need a small amount per application. Store in a cool, dry place and keep the cap tightly closed after each use.
Verdict: StriVectin SD Advanced PLUS Intensive Moisturizer is a premium, peptide-rich concentrate that delivers on its promises for wrinkle reduction and stretch mark improvement. Its standout strengths are the proprietary NIA-114 technology, the AI-designed Alpha-3 Peptide, and clinically backed results visible in as little as one week. The rich, nourishing formula is ideal for dry to normal and especially mature skin types seeking serious anti-aging benefits. The main trade-offs are the premium price point ($42.50–$37.25/oz), the presence of fragrance, and the fact that it's not suitable for fungal acne-prone skin. If you're willing to invest in a clinically tested, multi-peptide moisturizer that doubles as a stretch mark treatment, this is one of the most effective options on the market.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 0 |
Pentaerythrityl Tetraisostearate
Emollient, Emulsifying
|
|
|
| 0 |
Trimethylolpropane Tricaprylate/Tricaprate
Emollient, Skin Conditioning
|
|
|
| 1 |
Neopentyl Glycol Diheptanoate
Skin Conditioning, Emollient, Viscosity Increasing Agent
|
|






