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Sensibio DS+ Cream - Soothing Purifying Cream

Sensibio DS+ Cream - Soothing Purifying Cream

Product Description

Bioderma Sensibio DS+ Soothing Purifying Cream is a lightweight, fragrance-free gel-cream developed for sensitive facial skin prone to seborrheic dermatitis. Its dual anti-fungal and anti-inflammatory action helps limit Malassezia yeast, calm redness, soften scales and reduce flaking around the nose, eyebrows, forehead and chin.

๐Ÿ‡ซ๐Ÿ‡ท French Pharmacy ยท Made in France
โœ” Fragrance-Free โœ” Non-Comedogenic โœ” Hypoallergenic โœ” Anti-Malassezia โœ” Dermatologist-Tested โœ” For Seborrheic Dermatitis
Pregnancy Safe
Caution โš ๏ธ
Fungal Acne Safe
Caution โš ๏ธ
Comedogenic Rating
2/5
๐Ÿ“
Size
40ml / 1.3 fl oz
๐Ÿงด
Formulation
Gel-Cream
๐ŸŒ
Origin
France
โณ
PAO
12 Months
๐ŸŽฏ
Target
Seborrheic Dermatitis

โœจ Texture & Feel

๐Ÿ’ง
Consistency
Light gel-cream
๐Ÿ‘ƒ
Scent
Fragrance-free
โฑ๏ธ
Absorption
Fast, non-greasy
๐ŸŽฏ
Finish
Natural, matte-ish
๐Ÿ„

Anti-Fungal Action

Piroctone Olamine, Climbazole and Glyceryl Undecylenate work together to limit Malassezia yeast, a key trigger of seborrheic dermatitis flare-ups.

๐ŸŒฟ

Soothes Redness & Itching

Enoxolone (licorice-derived glycyrrhetinic acid) and coconut oil calm inflammation and visibly reduce redness and tightness.

โ„๏ธ

Reduces Flaking & Scales

Emollient agents soften scales and help lift flakes for a smoother, more comfortable complexion.

๐Ÿฆ 

Microbiome Support

The patented D.A.F. complex with prebiotic sugars (xylitol, mannitol, rhamnose, fructooligosaccharides) reinforces the skin's tolerance threshold.

๐Ÿ›ก๏ธ Safety & Compatibility

โš ๏ธ
Pregnancy & Breastfeeding

Contains azole-type antifungals (climbazole) plus piroctone olamine. Topical absorption is low, but as this is a treatment cream you should confirm with your doctor first.

โš ๏ธ
Fungal Acne (Malassezia)

Formulated to fight Malassezia, yet it contains coconut oil and esters that strict fungal-acne checkers flag. Most seborrheic-dermatitis users tolerate it well; patch test if reactive.

โœ…
Fragrance-Free & Hypoallergenic

No added fragrance and a high-tolerance formula make it suitable for reactive, easily irritated skin.

โœ…
Dermatologist-Tested

Clinically studied on facial seborrheic dermatitis and formulated for very good skin tolerance.

๐Ÿงช
Patch Test Advised

Propylene glycol and sorbitan sesquioleate can irritate very sensitive users; test on a small area first.

๐Ÿšซ
Avoid Broken Skin

Do not apply to clearly irritated, oozing or broken skin. Seek professional advice if symptoms persist.

๐Ÿ”ฌ Ingredient Breakdown

๐ŸŒฟ Glycyrrhetinic Acid (Enoxolone) ~0.5โ€“1% Proven

A licorice-root derived compound and one of the cream's key soothing actives. It calms inflammation, reduces visible redness and has antioxidant and antibacterial properties.

  • Source: Shown to alleviate dermatitis and protect skin against UV-B induced damage.
  • Role: Anti-inflammatory and skin-soothing agent for reactive skin.

๐Ÿ„ Piroctone Olamine ~0.5% Proven

A water-soluble antifungal active commonly used in anti-dandruff care. It is particularly effective against Malassezia, the yeast linked to dandruff and seborrheic dermatitis.

  • Source: Widely used to control Malassezia overgrowth on skin and scalp.
  • Role: Targets the root microbial trigger of seborrheic dermatitis.

๐Ÿ›ก๏ธ Climbazole ~0.5% Proven

A topical azole antifungal and preservative. In combination with piroctone olamine it helps relieve seborrheic dermatitis and eczema-type flaking.

  • Source: Established antifungal used to treat eczema and seborrheic dermatitis.
  • Role: Reinforces the cream's anti-Malassezia action.
โš ๏ธ
Azole antifungals are best confirmed with a doctor during pregnancy or breastfeeding.

๐Ÿฅฅ Cocos Nucifera (Coconut) Oil ~5โ€“8% Promising

Listed second on the INCI, this emollient is rich in fatty acids that trap moisture and soften skin, helping calm and comfort flaky areas.

  • Source: Lauric-acid-rich oil valued for moisturizing and skin-softening effects.
  • Role: Soothing emollient that helps reduce tightness and scaling.
โš ๏ธ
Coconut oil is comedogenic in isolation and not strictly fungal-acne safe, though the finished formula is brand-tested as non-comedogenic.

๐Ÿฆ  D.A.F. Complex โ€“ Mannitol, Xylitol, Rhamnose & Fructooligosaccharides Blend Promising

Bioderma's patented prebiotic sugar complex. These humectants hydrate the skin while supporting a balanced microbiome and raising the skin's tolerance threshold to external stress.

  • Source: Xylitol reduces transepidermal water loss; fructooligosaccharides act as prebiotics that reinforce the skin's microbiome.
  • Role: Long-term comfort and resilience for reactive skin.

๐ŸŒŠ Laminaria Ochroleuca Extract Low % Promising

A brown kelp extract containing lipids and antioxidants. It nourishes the skin barrier and helps soothe and reduce inflammation in sensitive skin.

  • Source: Known to calm and reduce skin inflammation while delivering antioxidants.
  • Role: Supports barrier nourishment and soothing.

20 ingredients

Aqua/Water/Eau, Cocos Nucifera (Coconut) Oil, Propylene Glycol, Caprylic/Capric Triglyceride, Dimethicone, Glycyrrhetinic Acid, Sorbitan Sesquioleate, Piroctone Olamine, Glyceryl Undecylenate, Climbazole, Mannitol, Xylitol, Rhamnose, Fructooligosaccharides, Laminaria Ochroleuca Extract, Cetyl Alcohol, Carbomer, Sclerotium Gum, Sodium Hydroxide, Phenoxyethanol.

FREE FROM: Fragrance/Perfume, Parabens, Sulfates, Harsh Alcohols, Common Allergens, Mineral Oil

๐Ÿ”„ Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Serum
4
Sensibio DS+ Cream
5
Moisturizer
6
Sunscreen (AM)

Apply as your targeted treatment after cleansing. On normal-to-oily skin it can double as your moisturizer; very dry skin can layer a richer cream on top. Always finish with SPF in the morning.

๐Ÿ“ How to Use

1

Cleanse

Wash with a gentle cleanser (ideally the Sensibio DS+ Cleansing Gel) and pat skin dry.

2

Apply to Affected Areas

Take a small amount and apply to redness- and flaking-prone zones: nostrils, eyebrows, forehead and chin.

3

Massage In

Gently massage until fully absorbed. The light texture sinks in fast without greasiness.

4

Use Daily

Apply once or twice a day, morning and/or evening. Avoid clearly irritated or oozing skin.

5

Protect

Follow with a broad-spectrum sunscreen in the morning to protect sensitized skin.

๐Ÿ‘ค Who Is It For?

โœ… Perfect for you if:

  • You have seborrheic dermatitis with redness, itching and flaking
  • You have sensitive, reactive or redness-prone skin
  • You want a lightweight, fragrance-free daily treatment
  • You prefer a clinically studied French-pharmacy formula
  • You need something that works under makeup

โŒ Consider alternatives if:

  • You have very dry skin needing rich, occlusive hydration
  • You strictly avoid coconut oil and comedogenic oils
  • You expect an instant, one-time cure (it's a maintenance treatment)
  • You're pregnant and prefer to avoid azole antifungals without a doctor's sign-off

๐ŸŽฏ Skin Type Compatibility

Oily Skin โ˜…โ˜…โ˜…โ˜…โ˜… Excellent

Non-greasy gel-cream controls seborrheic flaking without adding shine.

Combination โ˜…โ˜…โ˜…โ˜…โ˜… Excellent

Targets oily, SD-prone zones around the nose and brows while staying light elsewhere.

Sensitive โ˜…โ˜…โ˜…โ˜…โ˜… Excellent

Fragrance-free and hypoallergenic with very good clinical tolerance.

Dry Skin โ˜…โ˜…โ˜…โ˜†โ˜† Moderate

Soothes well but the light texture may need a richer moisturizer layered on top.

Acne-Prone โ˜…โ˜…โ˜…โ˜…โ˜† Good

Brand-tested non-comedogenic, but it contains coconut oil โ€” patch test if highly breakout-prone.

๐Ÿ“ˆ Results Timeline

Days 1โ€“7

Immediate Soothing

Redness and itching begin to calm; skin feels more comfortable and less tight from the first applications.

~60% noticed
Weeks 2โ€“4

Reduced Flaking

Scales soften and become easier to remove, and visible flaking around the nose and brows decreases.

~70% noticed
8 Weeks (2 Months)

Full Clinical Results

Per Bioderma's clinical study on facial seborrheic dermatitis (21 subjects, 56 days), symptoms were visibly reduced with continued daily use.

~75% noticed

โญ Ratings by Platform

๐Ÿ’„ Sephora UK
โ˜…โ˜…โ˜…โ˜… 4.3
Rating
200+
Reviews
โš ๏ธ Main complaint: The 40ml tube feels small for the price.
๐Ÿ›’ Amazon
โ˜…โ˜…โ˜…โ˜… 4.4
Rating
1,200+
Reviews
โš ๏ธ Main complaint: Coconut oil high on the list worries some acne-prone buyers.
๐Ÿ  Notino / Brand
โ˜…โ˜…โ˜…โ˜… 4.5
Rating
300+
Reviews
โš ๏ธ Main complaint: Not hydrating enough on its own for very dry skin.

โš–๏ธ Pros & Cons

โœ… Praised

  • Effectively calms seborrheic redness and flaking
  • Lightweight, non-greasy and works under makeup
  • Fragrance-free, hypoallergenic and well-tolerated
  • Clinically studied for facial seborrheic dermatitis
  • Affordable French-pharmacy pricing

โŒ Criticized

  • Small 40ml tube runs out quickly
  • Contains coconut oil (comedogenic concern)
  • A maintenance product, not a permanent cure
  • May not hydrate very dry skin enough alone
  • Azole antifungal means a pregnancy caution

๐Ÿ’ฐ Budget-Friendly Alternatives (Dupes)

68% Match
Noble Formula 2% Pyrithione Zinc Cream
$23.95 Similar

Uses zinc pyrithione as the antifungal instead of piroctone olamine and climbazole. Larger size and simpler base, but lacks the soothing enoxolone and prebiotic complex.

62% Match
Honeydew Seborrheic Dermatitis Cream
$14.95 Budget Pick

A more natural, plant-oil approach with tea tree and jojoba. Cheaper, but less clinically backed and not specifically formulated for facial SD.

55% Match
CeraVe SA Smoothing Cream
$15.99 Budget Pick

Salicylic acid plus ceramides exfoliate scales and support the barrier, but there's no antifungal action against Malassezia, so it tackles flaking differently.

๐Ÿ”„ Comparison with Competitors

Ducray Kelual DS Cream

$28.00
Key Actives Ciclopirox + Zinc Pyrithione
Soothing Agent Glycerin
Fragrance Fragranced
Size 40ml
Best For Stubborn, persistent flaking

Noble Formula 2% Pyrithione Zinc

$23.95
Key Actives 2% Zinc Pyrithione
Soothing Agent Emu Oil
Fragrance Fragrance-Free
Size 113g (larger)
Best For Face & body SD on a budget

CeraVe SA Smoothing Cream

$15.99
Key Actives Salicylic Acid (exfoliant)
Soothing Agent Ceramides + Niacinamide
Fragrance Fragrance-Free
Size 340g (largest)
Best For Scaling & rough texture (no antifungal)

๐Ÿ“ฆ Storage & Shelf Life

๐Ÿ“…
Period After Opening (PAO)

12 months after opening

๐Ÿ 
Storage

Store in a cool, dry place away from direct sunlight; close the tube tightly after use.

๐Ÿ“ฆ
Packaging

40ml squeeze tube

โœˆ๏ธ
Travel Friendly

Yes โ€” at 40ml it's well under the 100ml carry-on limit.

โ“ Frequently Asked Questions

It contains the azole antifungal climbazole plus piroctone olamine and glyceryl undecylenate. Topical absorption is generally low and there are no retinoids, salicylic acid, hydroquinone or chemical sunscreens. However, because it is a treatment cream containing antifungal actives, it's best to confirm with your doctor or midwife before using during pregnancy or breastfeeding.

This is nuanced. The cream is specifically designed to fight Malassezia with piroctone olamine, climbazole and glyceryl undecylenate โ€” so many people use it precisely to manage Malassezia-driven conditions. At the same time it contains coconut oil, caprylic/capric triglyceride and sorbitan sesquioleate, which strict fungal-acne checkers flag as potential triggers. Most seborrheic-dermatitis users tolerate it well, but if you have classic fungal acne and react to oils and esters, patch test first.

Yes, generally. The formula has no actives that strongly conflict with retinol, vitamin C, AHAs or BHAs. To avoid over-irritating already sensitive skin, introduce strong actives gradually โ€” for example use exfoliating acids or retinol in the evening and the DS+ cream as your soothing layer, and always patch test new combinations.

It's best for oily, combination and sensitive skin prone to seborrheic dermatitis โ€” redness, itching and flaking around the nose, eyebrows, forehead and chin. Dry skin can use it but may need a richer moisturizer layered on top, since the texture is deliberately light and non-greasy.

Many users feel soothing relief from redness and itching within the first week. Flaking typically reduces over 2โ€“4 weeks. Bioderma's clinical study on facial seborrheic dermatitis (21 subjects over 56 days) showed visibly reduced symptoms after about two months of consistent daily use.

Apply it after cleansing (and any serum) as your targeted treatment. On normal-to-oily skin it can act as your moisturizer; on dry skin, layer a richer cream over it. In the morning, always finish with sunscreen. Use once or twice daily on clean, dry skin.

Bioderma tests and markets the finished cream as non-comedogenic, and we rate it around 2/5. The caveat is coconut oil, which sits second on the ingredient list and is comedogenic in isolation. Most users don't break out, but if you're very breakout-prone, patch test on a small area first.

The Period After Opening (PAO) is 12 months. After opening, use it within a year and store it in a cool, dry place away from direct sunlight for best stability.

โ˜…โ˜…โ˜…โ˜…โ˜†
4.2 out of 5

Verdict: Bioderma Sensibio DS+ is a well-priced, clinically studied French-pharmacy treatment that genuinely helps calm the redness, itching and flaking of facial seborrheic dermatitis. Its dual antifungal-plus-soothing approach, fragrance-free formula and lightweight feel make it a strong daily-use option for oily, combination and sensitive skin. The main trade-offs are the small 40ml tube, the presence of coconut oil that gives acne-prone users pause, and the reality that it manages rather than permanently cures the condition. For most people dealing with face SD, it's an easy, effective recommendation โ€” just keep expectations on "control and comfort" rather than "one-time fix."

Product Overview

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Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

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Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

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lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging ยซpromisesยป it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

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Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

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dry-skin Dry Skin
1
oily-skin Oily/Acne-Prone Skin
sensitive-skin Sensitive Skin
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lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
55% 20% 25%

Product ingredient list

Showing first 5 of 20 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
0 Unknown
Cocos Nucifera Oil
Masking, Perfuming, Skin Conditioning
Hydrating
3 B
Propylene Glycol
Solvent, Skin Conditioning, Fragrance, Humectant, Viscosity Controlling, Viscosity Decreasing Agent, Skin-Conditioningagent - Miscellaneous
Hydrating
1 A
Caprylic/Capric Triglyceride
Solvent, Skin Conditioning, Masking, Perfuming, Emollient
3 A
Dimethicone
Skin Conditioning, Emollient, Antifoaming Agent, Skin Protecting
VIEW ALL INGREDIENTS