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Silymarin CF

Silymarin CF

Product Description

SkinCeuticals Silymarin CF

Oil-Free Vitamin C Serum for Oily & Blemish-Prone Skin

🇺🇸 Medical-Grade Skincare ✔ Oil-Free Formula ✔ Dermatologist Developed ✔ Clinically Tested ✔ Fungal Acne Safe

📋 Quick Info

🇺🇸
Origin
USA
🤰
Pregnancy
No ✗
🍄
Fungal Acne
Yes ✔
🔬
Comedogenic
0
💧
Texture
Watery Serum
👃
Scent
Characteristic*
⏱️
Absorption
30-60 seconds
Finish
Matte

*Contains L-ascorbic acid which has a characteristic oxidative scent

✨ Key Benefits

🛡️

Environmental Protection

Powerful antioxidant blend neutralizes free radicals from UV and pollution exposure

🧴

Oil Control

Reduces oil oxidation by up to 76% and decreases skin oiliness by 16% in just one week

🌟

Blemish Prevention

Prevents oil oxidation that can lead to breakouts and helps clear existing congestion

🔬

Anti-Aging

Improves fine lines by up to 24% after 8 weeks with advanced antioxidant protection

💎

Skin Clarity

78% of users saw improvement in skin clarity and overall complexion evenness

🎯

Pore Refinement

Salicylic acid gently exfoliates to refine skin texture and minimize pore appearance

🛡️ Safety Information

⚠️
Pregnancy

Not recommended. Contains 0.5% salicylic acid (BHA) which should be avoided during pregnancy. Consult your healthcare provider.

⚠️
Breastfeeding

Use with caution. While topical salicylic acid at low concentrations has limited absorption, it's best to consult your doctor before use.

Fungal Acne (Malassezia) Safe

This formula is free from oils, ferments, fatty acids, esters, and polysorbates that feed malassezia yeast. Safe for fungal acne sufferers.

Non-Comedogenic

Oil-free formula with a comedogenic rating of 0. Designed specifically to not clog pores or trigger breakouts.

ℹ️
Contains Denatured Alcohol

Second ingredient is alcohol denat. (>15%). May cause dryness for some skin types. Layer with hydrating products if needed.

ℹ️
Sun Sensitivity

Vitamin C and salicylic acid can increase sun sensitivity. Always follow with broad-spectrum SPF 30+ sunscreen.

🧪 Key Ingredients

🍊 L-Ascorbic Acid 15% Proven

The gold standard form of vitamin C, proven to neutralize free radicals, stimulate collagen synthesis, and brighten skin. At 15%, this is the optimal concentration for efficacy without excessive irritation.

  • Research: L-ascorbic acid at 15% provides optimal antioxidant protection per Duke University studies
  • Benefit: Protects against UV and pollution damage, stimulates collagen production
  • pH Level: Formulated at low pH (2.5-3.5) for maximum absorption
ℹ️
L-ascorbic acid oxidizes over time. Store in cool, dark place and use within 3-4 months of opening.

🌿 Silymarin (Milk Thistle) 0.5% Proven

A powerful plant-based antioxidant derived from milk thistle that specifically targets oil oxidation—a key trigger for blemish formation. This is the unique differentiator of this formula.

  • Research: Studies show silymarin has potent antioxidant and anti-inflammatory properties
  • Benefit: Prevents sebum oxidation which leads to breakouts and premature aging
  • Unique: Replaces vitamin E found in CE Ferulic, making it suitable for oily/acne-prone skin

🌾 Ferulic Acid 0.5% Proven

A plant-based antioxidant that stabilizes and enhances the efficacy of vitamin C. Provides synergistic protection against environmental damage.

  • Research: Doubles vitamin C's photoprotective effects when combined (Duke study)
  • Benefit: Stabilizes the formula and boosts overall antioxidant activity

💊 Salicylic Acid 0.5% Proven

A beta-hydroxy acid (BHA) that penetrates into pores to dissolve excess sebum and dead skin cells. Provides gentle exfoliation and anti-inflammatory benefits.

  • Research: BHA is oil-soluble, allowing it to penetrate and unclog pores
  • Benefit: Refines texture, minimizes pores, and prevents blackheads
⚠️
While concentration is low, avoid during pregnancy. May increase sun sensitivity—always use SPF.

📋 Full Ingredient List (11 Ingredients)

Aqua/Water/Eau, Alcohol Denat., Ascorbic Acid, Propylene Glycol, Dipropylene Glycol, Laureth-23, Silybum Marianum Fruit Extract, Sodium Citrate, Salicylic Acid, Ferulic Acid, D251110/1

🚫 Free From

✓ Oil-Free ✓ Fragrance-Free ✓ Paraben-Free ✓ Silicone-Free ✓ Sulfate-Free ✓ No Vitamin E

📍 Where It Goes in Your Routine

Use in the morning after cleansing and toning, before other serums and moisturizer.

1
Cleanser
2
Toner
3
Silymarin CF
4
Serum
5
Moisturizer
6
Sunscreen

📝 How to Use

1

Prep & Dispense

After cleansing and toning, dispense 4-5 drops into the palm of your hand. Ensure skin is completely dry.

2

Apply & Press

Using fingertips, gently press the serum into face, neck, and chest. Avoid rubbing—patting helps absorption.

3

Wait & Layer

Allow 1-2 minutes for absorption before applying next products. Follow with other serums, moisturizer, and always SPF.

4

Daily Use

Use every morning for best results. With 4-5 drops daily, one bottle lasts approximately 3-4 months.

👤 Skin Type Compatibility

Oily Skin ★★★★★ Excellent

Specifically designed for oily skin. Oil-free formula reduces sebum production and leaves a matte finish without adding shine.

Combination Skin ★★★★★ Excellent

Balances well across different face zones. Controls T-zone oiliness without over-drying cheeks.

Acne-Prone Skin ★★★★★ Excellent

Non-comedogenic, fungal acne safe formula with BHA to prevent breakouts and unclog pores.

Normal Skin ★★★★☆ Good

Works well but CE Ferulic may be better suited. Alcohol content may be unnecessary for balanced skin.

Dry Skin ★★★☆☆ Moderate

High alcohol content may be too drying. Consider CE Ferulic instead, or layer with hydrating products.

Sensitive Skin ★★★☆☆ Moderate

Potent formula with active acids. Patch test first. Start with every other day use and build tolerance.

📈 Expected Results Timeline

Week 1

Reduced Oiliness

Noticeable decrease in skin oiliness and shine throughout the day. Skin feels less greasy.

16% reduction in oiliness
Week 2-4

Improved Clarity & Texture

Skin appears brighter and more radiant. Pores look refined and texture becomes smoother.

76% reduction in oil oxidation
Week 4-6

Fewer Breakouts

Reduction in new blemishes forming. Existing congestion clears as BHA works to unclog pores.

78% saw clearer skin
Week 8+

Anti-Aging Benefits

Visible improvement in fine lines, wrinkles, and overall skin tone evenness. Enhanced environmental protection.

24% improvement in fine lines

⭐ Review Summary

🛒 Amazon
★★★★ 4.4
Rating
500+
Reviews
⚠️ Main complaint: High price point and strong characteristic scent
💄 Dermstore
★★★★ 4.5
Rating
300+
Reviews
⚠️ Main complaint: Small bottle size for the premium price
💅 LovelySkin
★★★★ 4.6
Rating
200+
Reviews
⚠️ Main complaint: Some users experienced initial breakouts (purging)
🏠 Brand Website
★★★★★ 4.7
Rating
500+
Reviews
⚠️ Main complaint: Sticky feel immediately after application
★★★★☆
4.5 / 5

Highly effective for oily and acne-prone skin. Premium price justified by clinical results and dermatologist-backed formulation.

💰 Budget-Friendly Alternatives

80% Match
Timeless 20% Vitamin C + E Ferulic Acid Serum
$24.95 Budget Pick

Higher vitamin C concentration (20% vs 15%). Contains vitamin E instead of silymarin—may not be ideal for very oily skin. Lacks salicylic acid.

67% Match
Obagi Fx C-Clarifying Serum
$98.00 Similar

Contains vitamin C with arbutin for brightening. Different antioxidant blend without silymarin. Also targets oily/acne-prone skin.

73% Match
Paula's Choice C15 Super Booster
$52.00 Budget Pick

15% vitamin C with vitamin E and ferulic acid. Contains vitamin E so may not be as suitable for very oily skin. No BHA.

85% Match
Brandefy Vit C + Silym Clarify Serum
$49.00 Best Dupe

Closest formula match with vitamin C, silymarin, and salicylic acid. Specifically designed as a Silymarin CF alternative at a fraction of the price.

📊 Product Comparison

SkinCeuticals CE Ferulic

$182
Vitamin C 15% L-Ascorbic Acid
Key Differentiator 1% Vitamin E
BHA Content None
Best For Normal/Dry/Aging
Size 30ml / 1 fl oz
Cost Per ml $6.07/ml

Timeless Vitamin C Serum

$24.95
Vitamin C 20% L-Ascorbic Acid
Key Differentiator 1% Vitamin E
BHA Content None
Best For All Skin Types
Size 30ml / 1 fl oz
Cost Per ml $0.83/ml

❓ Frequently Asked Questions

No, Silymarin CF is not recommended during pregnancy due to its 0.5% salicylic acid content. While the concentration is low for topical use, medical professionals generally advise avoiding BHAs during pregnancy. For breastfeeding, consult your healthcare provider—while topical absorption is minimal, it's best to discuss with your doctor. SkinCeuticals CE Ferulic (without salicylic acid) may be a safer alternative during this time.

Yes, Silymarin CF is fungal acne safe. The formula is free from oils, fermented ingredients, fatty acids, esters, and polysorbates that can feed malassezia yeast. The oil-free, lightweight formula makes it an excellent choice for those dealing with fungal acne while still wanting the benefits of a potent vitamin C serum.

Silymarin CF already contains vitamin C and BHA (salicylic acid), so you don't need additional vitamin C products. For retinol: use Silymarin CF in the morning and retinol at night to avoid irritation. For additional AHA/BHA: proceed with caution as Silymarin CF contains 0.5% salicylic acid—adding more acids may cause over-exfoliation. If using additional exfoliants, alternate days. Silymarin CF pairs well with niacinamide.

Silymarin CF is specifically designed for oily and blemish-prone skin. It's excellent for combination skin (especially oily T-zones) and acne-prone skin types. The oil-free formula with silymarin (instead of vitamin E found in CE Ferulic) prevents the oiliness and breakouts some users experience with other vitamin C serums. It's not ideal for dry or dehydrated skin due to the high alcohol content—those skin types should consider CE Ferulic instead.

Results timeline varies but most users report: Week 1 - Reduced oiliness and shine (16% reduction clinically proven). Weeks 2-4 - Improved skin clarity, radiance, and refined pores (76% reduction in oil oxidation). Weeks 4-6 - Fewer breakouts and clearer complexion. Week 8+ - Visible improvement in fine lines (24% improvement clinically proven) and overall skin tone. For best results, use consistently every morning.

Apply Silymarin CF in the morning only, after cleansing and toning, on completely dry skin. Use 4-5 drops, press gently into face, neck, and chest. Wait 1-2 minutes for absorption, then follow with your other serums, moisturizer, and always finish with SPF 30+. Do not use at night—vitamin C serums are most effective during the day when they can protect against environmental damage.

No, Silymarin CF has a comedogenic rating of 0 and is specifically formulated not to clog pores. The oil-free formula contains no ingredients known to cause comedones. In fact, the 0.5% salicylic acid actively helps unclog pores. Some users experience initial "purging" (temporary breakouts) as the BHA brings existing congestion to the surface, but this typically resolves within 2-4 weeks.

Once opened, use Silymarin CF within 3-4 months for optimal efficacy. L-ascorbic acid oxidizes when exposed to air, light, and heat. Signs of oxidation include color change (turning yellow, orange, or brown) and loss of effectiveness. Store in a cool, dark place away from direct sunlight. The dropper bottle design helps minimize air exposure. With daily use of 4-5 drops, one 30ml bottle typically lasts 3-4 months.

📦 Product Details

📏
Size
30ml / 1 fl oz
🧪
Ingredients
11
📅
PAO
3-4 Months
🏠
Storage
Cool, Dark Place
💧
Packaging
Glass Dropper
✈️
Travel Friendly
Yes, Under 100ml

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 3 ingredient(s):
Ascorbic Acid Ferulic Acid Ceramide AP
brightening Brightening from 2 ingredient(s):
Ascorbic Acid Salicylic Acid
wound Promotes Wound Healing from 1 ingredient(s):
Ascorbic Acid
ache Ache-fighting from 1 ingredient(s):
Salicylic Acid
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
1 1
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
54% 27% 18%

Product ingredient list

Showing first 5 of 11 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
0 Unknown
Alcohol Denat.
1 A
Ascorbic Acid
Skin Conditioning, Masking, Fragrance, Antioxidant, Ph Adjuster, Buffering Agent, Buffering
brightening Brightening
anti-aging Anti-Aging
Promotes Wound Healing
Redness
Dark Spots
Texture
Pores
3 B
Propylene Glycol
Solvent, Skin Conditioning, Fragrance, Humectant, Viscosity Controlling, Viscosity Decreasing Agent, Skin-Conditioningagent - Miscellaneous
Hydrating
1 A
Dipropylene Glycol
Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling
VIEW ALL INGREDIENTS