Soybean Panthenol Cream
Soybean Panthenol Cream
Product Description
Product overview
A deeply nourishing barrier cream featuring 1% Black Soybean Extract and Panthenol with Nano Niosome technology. Clinically proven to provide 120-hour hydration while strengthening the skin barrier with a ceramide-cholesterol-fatty acid complex that mirrors the skin's natural structure.
Jeongseon Black Soybean Extract (1%)
Sourced from Korea's pristine mountainous Jeongseon region. Contains 19.5x more anthocyanins and isoflavones than regular soybeans for superior antioxidant protection and skin firming.
Texture & feel
SENSORYJeongseon Black Soybean Extract (1%)
Sourced from Korea's pristine mountainous Jeongseon region. Contains 19.5x more anthocyanins and isoflavones than regular soybeans for superior antioxidant protection and skin firming.
Nano Niosome Panthenol Technology
Double-layered niosome structure delivers panthenol deeper into skin layers where it converts to Vitamin B5, strengthening hydration and barrier function from within.
Skin-Identical Lipid Complex
Ceramide NP, Ceramide AP, Cholesterol, and Fatty Acids in a ratio that mirrors the skin's natural structure for optimal barrier repair and moisture retention.
Squalane + Macadamia Oil
Plant-derived emollients that absorb quickly without greasiness, softening skin texture while creating a protective moisture-locking barrier.
Safety & compatibility
SAFEFree from retinoids, salicylic acid, hydroquinone, and chemical sunscreens. All ingredients are considered safe during pregnancy and nursing.
Contains Macadamia Seed Oil, Stearic Acid, Sorbitan Isostearate, and Hydrogenated Lecithin which may feed Malassezia yeast.
Generally non-comedogenic for most skin types. Unlikely to clog pores when used as directed.
Completed skin irritation testing and certified as non-irritating. Suitable for sensitive skin types.
Ingredient breakdown
INGREDIENTSPanthenol (Pro-Vitamin B5) 0.26%Proven
A powerful humectant that penetrates deep into skin layers and converts to Vitamin B5. Strengthens the skin barrier, promotes wound healing, and reduces inflammation.
- Mechanism: Attracts and retains water molecules; promotes fibroblast proliferation for collagen production
- Clinical Evidence: Studies show effective at concentrations as low as 0.35-0.80% for barrier strengthening
- Delivery System: Nano Niosome technology enhances penetration to deeper skin layers
Black Soybean Seed Extract 1%Proven
Premium black soybeans from Jeongseon, South Korea, rich in proteins, Vitamin E, genistein, and anthocyanins for comprehensive skin nourishment.
- Antioxidant Power: Contains 19.5x more anthocyanins than regular soybeans
- Brightening: Genistein inhibits melanin production to reduce hyperpigmentation
- Anti-Aging: Rich in Glycitein, a powerful anticancer and anti-aging substance
Ceramide Complex (NP + AP) 0.15-0.75%Proven
Two types of ceramides naturally found in the skin's outer layer. Makes up approximately 50% of the lipids between skin cells, essential for barrier function.
- Barrier Repair: Replenishes the intercellular matrix to prevent transepidermal water loss (TEWL)
- Synergy: Combined with Cholesterol and Fatty Acids in skin-identical ratios
- Clinical Result: 27.75% reduction in percutaneous moisture loss after 2 weeks
Squalane HighProven
A stable, hydrogenated form of squalene naturally found in human sebum. Excellent emollient compatible with all skin types including acne-prone skin.
- Compatibility: Non-irritating even at 100% concentration; biomimetic to skin's natural oils
- Benefits: Antioxidant, detoxifying, and moisture-locking properties
Adenosine Functional LevelProven
Korean MFDS-approved anti-wrinkle functional ingredient. Helps improve cell turnover and reduce the appearance of fine lines and wrinkles.
- Anti-Aging: Clinically proven to reduce dynamic wrinkles around eyes and forehead
- Timeline: Results typically visible after 6+ weeks of consistent use
39 ingredients
Water, Glycerin, Methylpropanediol, Squalane, Betaine, Cetearyl Alcohol, Vinyl Dimethicone, Cetyl Ethylhexanoate, Propylheptyl Caprylate, Glycine Max (Soybean) Seed Extract (10,000ppm), Macadamia Integrifolia Seed Oil, Panthenol (2,550ppm), Cholesterol, Ceramide NP, Glycosphingolipids, Ceramide AP, Stearic Acid, Tetraacetylphytosphingosine, Hydrogenated Lecithin, Dipropylene Glycol, Polyglyceryl-2 Stearate, Glyceryl Stearate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Stearyl Alcohol, Glyceryl Stearate SE, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Behenyl Alcohol, Tromethamine, Cetearyl Olivate, Sorbitan Olivate, Xanthan Gum, Adenosine, Disodium EDTA, Citric Acid, Sorbitan Isostearate, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Hydroxyacetophenone, Ethylhexylglycerin
Where it fits in your routine
ROUTINEApply as the final moisturizing step in your routine. Can be used morning and night. Layers well under sunscreen without pilling.
How to use
HOW TO USEPrep Your Skin
After cleansing and applying your toner, essence, and serum, prepare to seal in all that hydration with this barrier cream.
Dispense the Right Amount
Squeeze a pea-sized amount (about 1-2 pumps) onto your fingertips. A little goes a long way with this rich formula.
Apply to Face and Neck
Dot the cream across forehead, cheeks, nose, chin, and neck. Gently massage in upward circular motions until absorbed.
Pat for Better Absorption
Finish by gently patting your face to help the cream fully absorb. Wait 1-2 minutes before applying sunscreen in the morning.
Who is it for?
WHOPerfect for you if:
- Your skin barrier is compromised or weakened
- You experience dryness, flaking, or rough texture
- You're using retinol/tretinoin and need barrier support
- You want long-lasting hydration (120 hours!)
- You have sensitive skin that reacts to fragrances
- You're looking for a pregnancy-safe moisturizer
- You want anti-aging benefits with proven adenosine
Consider alternatives if:
- You have fungal acne (malassezia folliculitis)
- You prefer extremely lightweight gel textures
- Your skin is very oily in hot, humid weather
- You're allergic to soy-derived ingredients
- You need a completely oil-free formula
Skin type compatibility
SKIN TYPESIdeal match! Rich cream texture with ceramides and squalane provides deep, lasting nourishment for dehydrated skin.
Works well for combo skin. Use a smaller amount on the T-zone and more on dry areas. Great for winter months.
May feel heavy in summer. Best as a nighttime moisturizer or during colder seasons when skin needs extra nourishment.
Clinically tested non-irritating. Fragrance-free and soothing with panthenol. Excellent for reactive, sensitized skin.
Low comedogenic rating (1/5) makes it suitable for most. However, NOT recommended for fungal acne sufferers.
Contains adenosine (anti-wrinkle functional ingredient) and isoflavones. Excellent for addressing fine lines and loss of firmness.
Results timeline
WEEK 6+Immediate Hydration Boost
Skin feels instantly softer and more supple. Dry patches appear smoother. The rich cream provides an immediate moisture barrier.
85% noticed softer skinBarrier Improvement Begins
Clinical studies show 27.75% reduction in transepidermal water loss (TEWL). Skin retains moisture better throughout the day.
78% reported less drynessVisible Texture Improvement
Rough, flaky patches are significantly reduced. Skin appears smoother and more even. Redness from sensitivity may decrease.
72% saw smoother textureAnti-Aging Benefits Emerge
Adenosine begins to show results on fine lines. Skin appears firmer and more resilient. Soybean isoflavones help even skin tone.
65% noticed firmer skinRatings by platform
480+ REVIEWSPros & cons
BALANCEDPraised
- 120-hour hydration clinically proven
- Excellent for compromised/damaged skin barriers
- Fragrance-free and non-irritating
- Perfect for tretinoin/retinol users
- Triple ceramide complex mirrors skin structure
- Absorbs well without heavy greasiness
- Pregnancy and breastfeeding safe
- Layers beautifully under sunscreen
Criticized
- Not fungal acne safe
- 80ml size feels small for the price
- May be too rich for oily skin in summer
- Contains Macadamia oil (not for all skin)
- Lower panthenol concentration than some competitors
- Takes 30-60 seconds to fully absorb
Budget-friendly alternatives (dupes)
DUPES200ml size offers more value. Uses Ceramide PC-104 capsule technology. Also fragrance-free and excellent for barrier repair. Slightly thicker texture.
Higher panthenol concentration (10%). Contains Centella Asiatica and Niacinamide. Lighter texture, more suitable for oily skin. Vegan formula.
Centella-based formula with Ceramide NP. Contains fragrance (essential oils). Good for soothing redness. Slightly lighter consistency.
Medical-grade barrier cream from same parent company as ILLIYOON. 365-day skin barrier technology. Dermatologist-developed. Fragrance-free.
Comparison with competitors
SIDE-BY-SIDEPURITO B5 Panthenol Re-Barrier
Storage & shelf life
12 MONTHS12 months after opening. Look for the 12M symbol on packaging.
Store in a cool, dry place away from direct sunlight. Keep tightly sealed after use. No refrigeration required.
Squeezable tube with flip-top cap. Hygienic dispensing prevents contamination. Easy to control the amount.
Yes, 80ml is under the 100ml TSA liquid limit. Fits easily in carry-on toiletry bags.
Frequently asked questions
FAQYes, this cream is safe for use during pregnancy and breastfeeding. It does not contain any ingredients of concern such as retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe for expecting and nursing mothers. However, as with any skincare product, if you have specific concerns, consult with your healthcare provider.
No, this cream is NOT fungal acne safe. It contains several ingredients that can feed Malassezia yeast, including Macadamia Integrifolia Seed Oil, Stearic Acid, Sorbitan Isostearate, and Hydrogenated Lecithin. If you have fungal acne (Malassezia folliculitis), consider alternatives like certain La Roche-Posay or Sebamed products that are formulated to be fungal acne safe.
Absolutely! This cream is actually excellent to use with actives like retinol, tretinoin, vitamin C, AHA, and BHA. The ceramide-cholesterol-fatty acid complex helps repair and strengthen your skin barrier, which can become compromised when using these active ingredients. Apply your actives first, wait for absorption, then seal with this cream. Many users specifically purchase this for retinoid support.
This cream is best suited for dry, sensitive, mature, and combination skin types. It excels at providing deep, long-lasting hydration for dehydrated skin. Those with oily skin may find it too rich for daytime use in humid weather, but it can work well as a nighttime moisturizer. It's particularly excellent for anyone with a compromised skin barrier or those using retinoids.
You'll notice immediate hydration and softer skin from the first use. Clinical studies show a 27.75% reduction in moisture loss after 2 weeks of consistent use. For visible texture improvement and reduced roughness, expect 4 weeks. Anti-aging benefits from adenosine typically become noticeable after 6+ weeks of regular use, as changes occur in deeper skin layers.
Apply this cream as the final step of your moisturizing routine (before sunscreen in the morning). The order should be: Cleanser → Toner → Essence → Serum → This Cream → Sunscreen (AM) or Sleeping Mask (PM if desired). It layers well under sunscreen without pilling and can be used both morning and night.
This cream has a low comedogenic rating of 1 out of 5, meaning it's unlikely to clog pores for most people. It's clinically tested and certified as non-irritating. However, everyone's skin is different. If you're particularly prone to clogged pores, do a patch test first. Note that while low on the comedogenic scale, it is NOT fungal acne safe due to certain fatty acid-containing ingredients.
The Period After Opening (PAO) is 12 months. Once opened, use within one year for optimal efficacy and safety. The 80ml tube typically lasts 2-3 months with twice-daily use (using a pea-sized amount each time). Store in a cool, dry place away from direct sunlight and always close the cap tightly after use.
Verdict: The Round Lab Soybean Panthenol Cream is an excellent choice for anyone seeking deep, long-lasting hydration with proven barrier-repair benefits. Its skin-identical lipid complex (ceramides, cholesterol, fatty acids) and Nano Niosome panthenol technology deliver real results backed by clinical testing. The fragrance-free, pregnancy-safe formula makes it suitable for sensitive skin and those on retinoids. However, it's not for everyone: oily skin types may find it too rich for summer, and those with fungal acne should look elsewhere. At $25-32 for 80ml, it's pricier than some competitors like ILLIYOON which offers 200ml, but the premium Jeongseon black soybean extract and advanced delivery technology justify the investment for dry, damaged, or mature skin types seeking a reliable barrier cream.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Methylpropanediol
Solvent
|
|
|
| 1 |
Squalane
Skin Conditioning, Emollient, Hair Conditioning, Refatting
|
Hydrating
|
|
| 1 |
Betaine
Skin Conditioning, Humectant, Viscosity Controlling, Antistatic Agent, Hair Conditioning
|
Hydrating
Irritation
Dark Spots
|
|
| 1 |
Cetearyl Alcohol
Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent - Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling
|
|
|
| 0 |
Vinyldimethicone
|
|






