Time Revolution Night Repair Ampoule Cream 5X
Time Revolution Night Repair Ampoule Cream 5X
Product Description
Product overview
A rich yet fast-melting overnight repair cream from Missha, powered by 51% Extreme Biome™ — a blend of 10 highly concentrated fermented ingredients (triple-fermented) plus ceramides, niacinamide and centella. This 5th-generation formula is designed to flood mature, tired and dehydrated skin with overnight nourishment, strengthen the moisture barrier and visibly improve elasticity, radiance and the look of fine lines by morning.
51% Extreme Biome™
Over half the formula is a fermented complex of 10 probiotic-derived ingredients, led by Bifida Ferment Lysate, to nourish the skin microbiome and barrier.
Texture & feel
SENSORY51% Extreme Biome™
Over half the formula is a fermented complex of 10 probiotic-derived ingredients, led by Bifida Ferment Lysate, to nourish the skin microbiome and barrier.
Triple Fermentation
Ingredients undergo extreme, warm and cold fermentation plus low-temperature high-pressure extraction for highly concentrated, pure extracts.
Ceramide Barrier Repair
Ceramide NP and Ceramide AP help rebuild the lipid barrier, lock in moisture and reduce overnight transepidermal water loss.
Brighten & Smooth
Niacinamide and adenosine target dullness, uneven tone and the look of fine lines, while centella soothes stressed skin.
Safety & compatibility
SAFENo retinoids, salicylic acid, hydroquinone or chemical UV filters. Generally considered low-risk, but it contains essential oils and fragrance allergens — check with your doctor and patch test.
Not fungal-acne safe. Contains multiple ferments, fatty acids (palmitic, stearic, myristic), esters and plant oils that can feed Malassezia.
Contains limonene, linalool, citronellol and geraniol plus essential oils. Sensitive or reactive skin should patch test first.
Includes citrus-derived oils (bergamot, orange peel). Use at night and always apply broad-spectrum SPF in the morning.
Compatible with niacinamide, peptides, hyaluronic acid and most serums. A great barrier-supportive partner to gentler routines.
Ceramides, centella and the fermented biome focus on barrier repair, making the base formula soothing for dry, tired skin.
Ingredient breakdown
INGREDIENTSBifida Ferment Lysate #1 ingredientProven
The hero of the Extreme Biome™ complex and the very first ingredient on the list. This probiotic-derived ferment supports the skin microbiome, reinforces the barrier and is prized for soothing and anti-aging benefits — it's the same active that anchors many luxury "night repair" serums.
- Research: Studies link Bifida ferment to improved barrier function and reduced sensitivity in reactive skin.
- Function: Microbiome support, hydration and soothing.
Niacinamide (Vitamin B3) ~2–5%Proven
A multitasking form of vitamin B3 that strengthens the barrier, regulates oil, refines the look of pores and fades the appearance of dark spots and uneven tone. Sits high on the ingredient list (8th), suggesting a meaningful, functional level.
- Research: ~5% niacinamide is well-studied for brightening and barrier support.
- Function: Brightening, tone-evening, barrier reinforcement.
Ceramide NP + Ceramide AP Barrier lipidsProven
Identical-to-skin lipids that bond skin cells together and seal in moisture. Replenishing ceramides overnight helps repair a compromised barrier, reduce water loss and leave skin looking plumper and more resilient by morning.
- Research: Topical ceramides are well documented to restore barrier function in dry/aging skin.
- Function: Barrier repair, long-lasting hydration.
Centella Asiatica Extract SoothingProven
A famed K-beauty "cica" botanical rich in madecassoside and asiaticoside. It calms redness and irritation, supports wound healing and adds antioxidant defense, balancing the richer, oilier components of the formula.
- Research: Centella compounds are shown to reduce inflammation and support collagen.
- Function: Soothing, antioxidant, barrier support.
Adenosine Anti-wrinkleProven
A nucleoside active recognized in Korea as an approved anti-wrinkle ingredient. It supports the look of firmer, smoother skin and helps improve the appearance of fine lines over consistent use.
- Research: Adenosine is shown to improve the appearance of wrinkles and firmness.
- Function: Smoothing, firming, anti-aging.
Fermented Lactobacillus & Lactococcus Complex Part of 51% biomePromising
A cocktail of postbiotic ferments — Lactobacillus Ferment, Lactococcus Ferment Lysate, fermented soybean, pomegranate and acerola — that round out the Extreme Biome™ blend with antioxidant, hydrating and barrier-supportive benefits.
- Research: Postbiotics show promise for barrier repair and microbiome balance; evidence is still emerging.
- Function: Microbiome support, antioxidant, hydration.
84 ingredients
Bifida Ferment Lysate, Glycerin, Methylpropanediol, Cyclohexasiloxane, Hydrogenated Polyisobutene, Caprylic/Capric Triglyceride, Triethylhexanoin, Niacinamide, Cetearyl Alcohol, Water, Dimethicone, Stearyl Alcohol, Trehalose, Centella Asiatica Extract, Ficus Carica Fruit Extract, Dioscorea Japonica Root Extract, Oryza Sativa Extract, Phellodendron Amurense Bark Extract, Lactobacillus/Punica Granatum Fruit Ferment Extract, Lactobacillus/Soybean Ferment Extract, Monascus Extract, Solanum Melongena Fruit Extract, Daucus Carota Sativa Root Extract, Vaccinium Angustifolium Fruit Extract, Beta Vulgaris Root Extract, Brassica Oleracea Capitata Leaf Extract, Citrus Aurantium Bergamia Fruit Oil, Pelargonium Graveolens Flower Oil, Hydrogenated Lecithin, Camellia Sinensis Seed Oil, Camellia Japonica Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Fruit Oil, Macadamia Integrifolia Seed Oil, Helianthus Annuus Seed Oil, Simmondsia Chinensis Seed Oil, Lavandula Angustifolia Oil, Citrus Aurantium Dulcis Peel Oil, Anthemis Nobilis Flower Oil, Santalum Album Oil, Beeswax, Cetyl Alcohol, Cetearyl Glucoside, Vinyldimethicone, Polyglyceryl-2 Triisostearate, Cetearyl Olivate, Sorbitan Olivate, Glyceryl Stearate, Palmitic Acid, Stearic Acid, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glycosyl Trehalose, Xanthan Gum, Hydrogenated Starch Hydrolysate, Adenosine, Raffinose, Glyceryl Polymethacrylate, Dextrin, Theobroma Cacao Shell Powder, Lactobacillus Ferment, Lactococcus Ferment Lysate, Lactobacillus/Acerola Cherry Ferment, Lactobacillus Ferment Lysate, Lactococcus Ferment, Leuconostoc/Radish Root Ferment Filtrate, Disodium EDTA, Lecithin, Glucose, Polyquaternium-51, Ceramide NP, Myristic Acid, Sucrose Distearate, Dipropylene Glycol, Biosaccharide Gum-1, Saccharomyces Ferment, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Ceramide AP, 1,2-Hexanediol, Hydroxyacetophenone, Ethylhexylglycerin, Limonene, Citronellol, Geraniol, Linalool
Where it fits in your routine
ROUTINEUse as the last step of your PM routine to seal everything in. Pairs beautifully with the matching Night Repair Ampoule 5X serum underneath. Always follow with SPF the next morning.
How to use
HOW TO USECleanse & tone
Start with clean skin and your usual hydrating toner or essence so the cream layers smoothly.
Apply your serums first
Layer any treatment ampoules or serums and let them absorb before sealing.
Warm a small amount
Take a pea-to-almond-sized amount — a little goes a long way as it spreads easily.
Pat in gently
Smooth over face and neck, then pat until fully absorbed. Use nightly for best results.
Who is it for?
WHOPerfect for you if:
- You have dry, mature or dehydrated skin needing overnight nourishment
- You want a barrier-repairing, ferment-rich anti-aging cream
- You're after an affordable alternative to luxury "night repair" treatments
- You enjoy a rich, dewy, comforting cream texture
- You're targeting elasticity, radiance and the look of fine lines
Consider alternatives if:
- You have fungal acne (malassezia) — this is not FA-safe
- You're fragrance-sensitive or react to essential oils
- You have very oily or acne-prone skin (rich, oil-heavy base)
- You prefer a lightweight gel moisturizer
- You want a strictly minimalist, low-ingredient formula
Skin type compatibility
SKIN TYPESRich, ceramide-and-oil-packed base delivers deep, lasting overnight moisture.
Ferment biome, niacinamide and adenosine target elasticity, radiance and fine lines.
Comfortable in cooler months; may feel heavy on the T-zone in humidity.
Soothing ferments and centella help, but essential oils & allergens mean patch testing is essential.
Oil-rich, not fungal-acne safe and higher comedogenic load — better suited to drier skin.
Results timeline
6–8 WEEKSSoft, plumped, dewy skin
Most users report waking up to noticeably softer, more hydrated and "well-rested" looking skin — Missha cites improved skin condition after just 10 hours of use.
~80% noticedSmoother texture & glow
With nightly use, reviewers describe a more even, radiant tone and smoother surface texture, as the barrier becomes better supported.
~70% noticedFirmer, more resilient feel
Longer-term users note improved bounce and elasticity and a healthier-looking, more resilient skin barrier.
~60% noticedRatings by platform
6K+ REVIEWSPros & cons
BALANCEDPraised
- Skin feels soft, plump and "velvety" by morning
- Genuinely high 51% fermented biome concentration
- Ceramides + niacinamide + adenosine = strong anti-aging line-up
- Spreads easily — a little goes a long way
- Affordable luxe alternative to high-end night treatments
- Beautiful, protective heavy-glass packaging
Criticized
- Contains essential oils & EU fragrance allergens
- Not fungal-acne safe
- Too rich for oily/acne-prone skin
- Opaque jar hides remaining product
- Results on deep wrinkles are subtle, not dramatic
- Pricier than many simpler K-beauty creams
Budget-friendly alternatives (dupes)
DUPESAlso centered on Bifida Ferment Lysate and fermented biome for barrier and anti-aging benefits. More serum-like and lighter; less of the rich, occlusive cream texture.
Ginseng + niacinamide anti-aging cream with a richer, nourishing feel. Lacks the high fermented-biome concentration but shares the mature-skin, hydrating focus at a lower price.
Repair-focused cream led by snail mucin rather than ferments. Great value barrier hydrator, but a different hero ingredient and lighter anti-aging emphasis.
Comparison with competitors
SIDE-BY-SIDESK-II R.N.A. Power Cream
Storage & shelf life
12 MONTHS12 months after opening
Store in a cool, dry place away from direct sunlight; keep the lid closed tightly.
Premium heavy glass jar with screw lid (opaque to protect the formula).
Yes — 50 ml is well under the 100 ml carry-on limit (glass jar, pack carefully).
Frequently asked questions
FAQIt contains no retinoids, salicylic acid, hydroquinone or chemical sunscreens, so it has no commonly contraindicated actives and is generally considered low-risk. However, it does contain essential oils (bergamot, lavender, sandalwood, rose geranium) and fragrance allergens. As always during pregnancy or breastfeeding, confirm with your doctor and patch test first.
No. This cream contains numerous ferments, fatty acids (palmitic, stearic, myristic), esters and plant oils, several of which can feed Malassezia yeast. If you're prone to fungal acne, choose a fungal-acne-safe alternative instead.
Yes — as a barrier-supportive night cream it layers well over most actives and can actually help buffer irritation from retinol or acids when applied as the final step. Apply your retinol, vitamin C or exfoliating acid first, let it absorb, then seal with this cream. Introduce strong actives gradually and always use SPF in the morning.
It's best for dry, dehydrated, mature or tired skin that wants rich overnight nourishment and anti-aging support. Normal and combination skin can enjoy it (especially in cooler months), while very oily or acne-prone skin may find it too heavy.
Hydration and softness are usually visible the very next morning — Missha cites improved skin condition after 10 hours of use. Expect smoother texture and a more even glow around 2–4 weeks, with firmness and elasticity improving over 6–8 weeks of nightly use.
It's the last step of your evening routine: cleanser → toner/essence → serums/ampoules → eye cream → this cream (an optional sleeping mask can go on top). It pairs especially well layered over the matching Time Revolution Night Repair Ampoule 5X serum.
We rate it around 3/5 for comedogenicity. It contains beeswax, fatty alcohols and several plant oils (olive, macadamia, argan) that can clog pores on breakout-prone skin. Dry and normal skin generally tolerate it well; oily and acne-prone skin should be cautious.
The Period After Opening (PAO) is 12 months. Once opened, use it within a year and store it in a cool, dry place away from sunlight to keep the fermented actives fresh.
Verdict: The Missha Time Revolution Night Repair Ampoule Cream 5X is a genuinely impressive, ferment-rich overnight cream that punches well above its price. With 51% Extreme Biome™, ceramides, niacinamide and adenosine, it delivers soft, plumped, radiant "morning-after" skin and meaningful barrier and anti-aging support — earning its reputation as an affordable K-beauty alternative to luxury night treatments. The main caveats are its essential-oil/fragrance content, lack of fungal-acne safety and richness that suits dry-to-normal and mature skin far better than oily or breakout-prone skin. For its target audience, it's an easy recommendation and excellent value.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Bifida Ferment Lysate
Skin Conditioning
|
Hydrating
Irritation
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|
|
| 1 |
Methylpropanediol
Solvent
|
|
|
| 2 |
Cyclohexasiloxane
Solvent, Skin Conditioning, Emollient, Hair Conditioning
|
|
|
| 1 |
Hydrogenated Polyisobutene
Emollient, Skin Conditioning, Viscosity Controlling, Viscosity Increasing Agent
|
|





