Idebenone + Blackberry Complex Serum
Idebenone + Blackberry Complex Serum
Product Description
Product overview
A fast-absorbing antioxidant serum from Mary & May, packed with 1,000ppm Idebenone and a 20% Blackberry Complex (blackberry, açaí, blueberry). This fragrance-free, lightweight gel-liquid delivers a Coenzyme Q10 successor plus anthocyanin-rich berry extracts to neutralize free radicals, brighten dull tone, and defend against daily environmental stress — all in a clean, minimalist 16-ingredient formula.
Potent Antioxidant Defense
Idebenone — a smaller-molecule analog of Coenzyme Q10 — neutralizes free radicals from UV, pollution, and blue light.
Texture & feel
SENSORYPotent Antioxidant Defense
Idebenone — a smaller-molecule analog of Coenzyme Q10 — neutralizes free radicals from UV, pollution, and blue light.
20% Berry Anthocyanin Complex
Blackberry, açaí, and blueberry extracts deliver vitamin C, polyphenols, and anthocyanins for brightening and anti-aging support.
Gentle Vitamin C Alternative
Delivers brightening and anti-aging benefits without the sting, tingling, or oxidation issues common with L-ascorbic acid.
Minimalist Clean Formula
Only 16 ingredients. EWG Green Grade certified. Free from parabens, fragrance, alcohol, mineral oil, and common allergens.
Safety & compatibility
SAFEContains no retinoids, salicylic acid, hydroquinone, or chemical sunscreens. Idebenone and berry extracts are generally considered safe during pregnancy. Always consult your OB/GYN.
Contains Caprylic/Capric Triglyceride, Polyglyceryl-10 Laurate, and Hydrogenated Lecithin, which may feed Malassezia yeast. Skip if you have confirmed fungal acne.
Lightweight, oil-free base. No heavy butters, waxes, or high-comedogenic oils. Safe for most acne-prone users (outside fungal acne).
Fragrance-free, alcohol-free, essential-oil-free, and dermatologically tested. Patch test recommended if you've had prior reactions to Idebenone.
Plays well with hyaluronic acid, niacinamide, peptides, ceramides, and sunscreen. No acid or retinoid conflicts.
Redundant antioxidant pairing. Use Idebenone AM and Vitamin C PM (or vice versa) to avoid potential destabilization and over-loading.
Ingredient breakdown
INGREDIENTSIdebenone (Hydroxydecyl Ubiquinone) 0.1% / 1,000ppmProven
A synthetic analog of Coenzyme Q10 originally developed as a neuroprotective pharmaceutical. Smaller molecular weight than CoQ10 = better skin penetration and free-radical scavenging.
- Research: A 2005 American Academy of Dermatology study ranked idebenone above vitamin C, vitamin E, CoQ10, and kinetin on the Environmental Protection Factor antioxidant scale.
- Benefits: Reduces fine lines, improves skin texture, fades hyperpigmentation, and protects against UV-induced oxidative damage.
- Stability: More photostable than L-ascorbic acid — doesn't oxidize as quickly in the bottle.
Blackberry Fruit Extract (Rubus Fruticosus) 20% / 67,500ppmProven
The star berry — rich in vitamin C, anthocyanins, and ellagic acid. Anchors the "Blackberry Complex" name on the bottle.
- Source: Blackberries are among the highest-ORAC fruits, packed with phenolic acids that scavenge reactive oxygen species.
- Benefits: Helps defend against photo-aging from UV and infrared light, supports collagen via vitamin C content, and provides astringent tone-tightening.
Açaí Berry Extract (Euterpe Oleracea) ~6.75%Promising
Amazonian superfruit rich in anthocyanins, flavonoids, vitamin A, and healthy fatty acids.
- Research: Açaí has among the highest antioxidant capacities of any edible berry, with documented free-radical scavenging activity in vitro.
- Benefits: Supports skin firmness, fights oxidative stress, and contributes to the formula's natural deep-yellow color.
Blueberry Fruit Extract (Vaccinium Angustifolium) ~6.75%Promising
Wild lowbush blueberry extract, featured alongside blackberry and açaí to complete the 20% antioxidant complex.
- Source: Contains vitamin C, beta-carotene, glutathione, quercetin, and vitamin E — a broad-spectrum antioxidant cocktail.
- Benefits: Inhibits enzymes linked to discoloration and loss of firmness, while soothing irritation.
Glycerin ~2-3%Proven
Gold-standard humectant that draws moisture from the environment and deeper skin layers into the stratum corneum.
- Research: Effective from 3%, supports skin barrier function, keeps intercellular lipids in healthy liquid crystal state.
- Benefits: Rating of 0 for both irritancy and comedogenicity — making this serum suitable even for reactive skin.
Arginine ~0.1-0.35%Promising
Essential amino acid with mild antioxidant and barrier-repair properties.
- Source: Used by the skin to build keratin and collagen. Cationic charge makes it substantive — binds gently to the skin surface.
- Benefits: Supports repair of damaged skin; pairs well with berry-derived phenolics to neutralize free radicals.
16 ingredients
Water, Rubus Fruticosus (Blackberry) Fruit Extract, Euterpe Oleracea Fruit Extract, Vaccinium Angustifolium (Blueberry) Fruit Extract, Glycerin, Caprylic/Capric Triglyceride, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Polyglyceryl-10 Laurate, Hydroxydecyl Ubiquinone, Hydrogenated Lecithin, Arginine, Carbomer, Ethylhexylglycerin, Caprylyl Glycol.
Where it fits in your routine
ROUTINEApply after water-based toners/essences and before heavier creams. In the AM, always finish with broad-spectrum SPF — antioxidant serums amplify sunscreen's protective effect.
How to use
HOW TO USECleanse & Tone
Start with clean, slightly damp skin. Follow your usual cleanser and hydrating toner for best absorption.
Dispense 2-3 Drops
Using the dropper, place 2-3 drops on your fingertips or directly onto the face. A little goes a long way.
Gently Press Into Skin
Pat and smooth across face and neck, following the skin's natural contours. Avoid the immediate eye area.
Let Absorb (~30 Seconds)
Wait until fully absorbed — skin should feel soft, not sticky. Yellow tint fully disappears on skin.
Seal & Protect
Follow with moisturizer. In AM, always finish with SPF 30+ to complete your antioxidant defense.
Who is it for?
WHOPerfect for you if:
- You want antioxidant protection but find pure vitamin C irritating
- You're addressing early-to-mid signs of aging (dullness, fine lines)
- You live in a polluted city or get daily UV exposure
- You have sensitive skin and prefer fragrance-free, minimalist formulas
- You're pregnant or breastfeeding and want a safe anti-aging option
- You prefer clean beauty with EWG-verified ingredients
Consider alternatives if:
- You have confirmed fungal acne (Malassezia folliculitis)
- You've had a prior allergic reaction to Idebenone
- You already use a high-strength vitamin C in both AM and PM
- You need deep hydration (this is a treatment, not a moisturizer)
- You want visible wrinkle reversal — this is gentle, not aggressive
Skin type compatibility
SKIN TYPESLightweight, oil-free gel-liquid absorbs fast without residue. Won't clog pores or add shine.
Glycerin and arginine provide light hydration, but dry skin will need a richer moisturizer on top.
Balanced, water-based texture works evenly across T-zone and cheeks without over- or under-delivering.
Fragrance-free, alcohol-free, EWG Green Grade. Patch test first — Idebenone is a known (rare) allergen.
Non-comedogenic (1/5), but not fungal-acne safe due to esters and Polyglyceryl-10 Laurate.
Idebenone + anthocyanins directly target photo-aging, dullness, and fine lines for a brighter complexion.
Results timeline
MONTH 2-3Hydrated, Comfortable Skin
Skin feels plush and smooth immediately after application. The gel-liquid absorbs without tackiness, leaving a soft, non-greasy finish.
89% noticedBrighter, More Even Tone
Users report a subtle but visible "lit-from-within" glow as antioxidants reduce oxidative dullness. Makeup glides on more smoothly.
71% noticedSmoother Texture & Refined Pores
Consistent daily use begins to soften the look of fine lines, reduce rough patches, and improve the appearance of post-blemish marks.
64% noticedVisible Firmness & Photo-Damage Defense
Long-term antioxidant protection translates to a visibly more resilient, youthful complexion. Best used alongside daily SPF.
58% noticedRatings by platform
5K+ REVIEWSPros & cons
BALANCEDPraised
- High 1,000ppm Idebenone concentration at an accessible price
- Fast absorption, non-sticky, works beautifully under makeup
- Gentle alternative for those who react to L-ascorbic acid
- Minimalist 16-ingredient formula — easy to spot-check for sensitivities
- EWG Green Grade + cruelty-free + vegan-friendly
- Pregnancy and breastfeeding safe (no retinoids, no BHA)
- Visible brightening and smoother texture reported within 2-4 weeks
Criticized
- 30ml size is small — doesn't last long with twice-daily use
- Yellow-tinted formula can temporarily discolor white cloths
- Not fungal acne safe (esters + polyglyceryl laurate)
- Subtle results — not a dramatic anti-wrinkle transformation
- Idebenone is a known (rare) allergen; patch test required
- Doesn't provide enough hydration alone for dry skin
Budget-friendly alternatives (dupes)
DUPESDifferent active (resveratrol vs idebenone) but similar antioxidant goal. More potent on paper, but watery and less elegant. No berry complex.
Antioxidant + brightening K-beauty serum at similar price. Honey/propolis base vs berry complex. Slightly tackier, more hydrating for dry skin.
Peptide-based anti-aging approach, not antioxidant. Similar lightweight feel and minimalist formula, but targets firmness rather than free-radical defense.
K-beauty antioxidant serum with 5% vitamin C and berry blend. Closer texture and philosophy — may sting sensitive skin where Idebenone doesn't.
Comparison with competitors
SIDE-BY-SIDESkinCeuticals C E Ferulic
Elizabeth Arden Prevage Anti-Aging Serum
Storage & shelf life
12 MONTHS12 months after opening. Unopened: 30-36 months from manufacture date.
Store in a cool, dry place away from direct sunlight. Room temperature is ideal — no refrigeration needed.
Amber-tinted glass bottle with dropper applicator. Glass protects Idebenone from light-induced degradation.
Yes — 30ml fits well under the TSA 100ml carry-on liquid limit. Wrap the glass bottle for protection.
Frequently asked questions
FAQYes. The formula contains no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or essential oils — all categories typically flagged during pregnancy. Idebenone is a non-prescription cosmetic antioxidant with no known pregnancy contraindications, and the berry extracts are food-grade. As with any skincare change during pregnancy, it's best to clear new products with your OB/GYN or dermatologist.
No, this serum is not fungal acne safe. It contains Caprylic/Capric Triglyceride (a medium-chain triglyceride ester), Polyglyceryl-10 Laurate (a lauric acid derivative), and Hydrogenated Lecithin — all of which can feed Malassezia yeast. If you have confirmed fungal acne (small, uniform, itchy bumps on forehead/chest/back), consider fungal-acne-safe alternatives.
Yes, with some nuance. Retinol: use Idebenone in the AM and retinol at night — the combination offers 24-hour antioxidant protection. Vitamin C: avoid stacking on top, as you'd be doubling up on antioxidants; alternate days or use one AM and one PM. AHA/BHA: safe to alternate in your routine, but don't layer directly — apply acids first, wait 20-30 minutes, then apply this serum. The formula has no pH conflicts with acids.
It performs best on oily, combination, and normal skin thanks to its lightweight, oil-free gel-liquid texture. Mature skin benefits greatly from the antioxidant profile. Sensitive skin users appreciate the fragrance-free, alcohol-free formula — though a patch test is wise since Idebenone is a known (rare) allergen. Very dry skin should pair it with a richer moisturizer on top.
Immediate: softer, hydrated skin with a subtle healthy-looking finish. Week 1-2: a gentle brightening effect as oxidative dullness fades. Week 4-6: smoother texture, refined-looking pores, and reduced appearance of post-blemish marks. Month 2-3: cumulative photo-damage defense and visibly firmer skin. Antioxidants work preventatively — pair with SPF for best long-term results.
Apply after cleansing and toning, and before eye cream, moisturizer, and sunscreen. As a water-based serum, it sits early in the routine — after watery toners/essences but before any oil-based or creamy products. Use it both AM (for environmental antioxidant defense) and PM (for nighttime repair). Always follow with SPF 30+ in the morning.
No, this serum has a very low comedogenic rating (approximately 1/5). It contains no heavy butters, waxes, or high-comedogenic oils. The base is water with humectants, and the small amount of Caprylic/Capric Triglyceride is considered non-comedogenic for most users. Over 70% of acne-prone reviewers report no new breakouts (outside of fungal acne concerns).
The Period After Opening (PAO) is 12 months, as indicated by the open-jar symbol on the packaging. Unopened, it has a shelf life of approximately 30-36 months from manufacture. The amber-tinted bottle helps protect Idebenone from light-induced degradation. If the yellow color darkens significantly or the scent changes, discard it.
Verdict: Mary & May has bottled one of K-beauty's smartest anti-aging propositions — a 1,000ppm Idebenone serum with a 20% berry antioxidant complex, all in a clean, fragrance-free, EWG Green Grade formula for a fraction of what Western brands charge for idebenone. It's the ideal vitamin C alternative for sensitive skin, pregnancy-safe, and layer-friendly with the rest of your routine. Deductions go to the not-fungal-acne-safe formula and the petite 30ml size. If you want effective, gentle, preventative antioxidant defense without the price tag (or the sting), this is among the best values in Korean skincare.
Product Overview
Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.
Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.
Quick Product Notes
Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.
We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.
Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.
Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you
Notable Effects & Ingredients
Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.
We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.
A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.
One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!
Ingredients Related to Skin Types
Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.
EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.
Ingredient Safety Breakdown
Product ingredient list
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
| 1 |
Water
Solvent, Skin Conditioning
|
|
|
| 0 |
Rubus Fruticosus Fruit Extract
Astringent, Masking, Tonic
|
|
|
| 1 |
Euterpe Oleracea Fruit Extract
Hair Conditioning
|
Irritation
|
|
| 0 |
Vaccinium Angustifolium Fruit Extract
Skin Protecting, Soothing
|
Redness
Irritation
|
|
| 2 |
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
|
Promotes Wound Healing
Hydrating
|







