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PDRN Pink Collagen Capsule Cream

PDRN Pink Collagen Capsule Cream

Product Description

Product overview

Made in Various INTERNATIONAL

A dual-texture capsule cream featuring Salmon DNA PDRN, collagen, and niacinamide that brightens uneven skin tone, boosts elasticity by 33%, and delivers over 100% instant hydration for radiant glass-skin glow.

Dermatologist Tested Non-Comedogenic Fragrance-Free Paraben-Free Clinically Proven 6 Types of Hyaluronic Acid 5 Peptide Complex
Pregnancy
Caution
Fungal Acne
No
Comedogenic
2/5
Size
55g / 1.94 oz
Type
Cream
Concern
Anti-Aging
Hero
PDRN
Price
~$24-27
Real reviews · YouTube Shorts
Why it's different

Salmon DNA PDRN Technology

Encapsulated PDRN preserves potency until application, promoting cell regeneration and skin barrier repair with DNA fragments similar to human skin.

01

Texture & feel

SENSORY
Consistency
Gel + Capsules
Scent
Fragrance-Free
Absorption
Fast (30 sec)
Finish
Dewy Glow

Salmon DNA PDRN Technology

Encapsulated PDRN preserves potency until application, promoting cell regeneration and skin barrier repair with DNA fragments similar to human skin.

Customizable Dual-Texture

Mix pink capsules with clear gel to customize hydration level — more gel for lighter feel, more capsules for deeper moisture and firming.

5 Peptide Complex

Features Acetyl Hexapeptide-8, Copper Tripeptide-1, and Palmitoyl peptides that work synergistically to firm skin and reduce fine lines.

6 Types of Hyaluronic Acid

Multi-weight hyaluronic acids penetrate different skin layers for deep hydration that lasts, with clinically proven 102.4% immediate hydration boost.

02

Safety & compatibility

SAFE
Pregnancy & Breastfeeding

Limited research on topical PDRN during pregnancy. Consult your healthcare provider before use. No retinoids, salicylic acid, or hydroquinone present.

Fungal Acne (Malassezia)

Contains Ethylhexyl Palmitate, Polysorbate 20, and olive-derived emulsifiers that may feed malassezia yeast. Not recommended for fungal acne-prone skin.

Sensitive Skin Friendly

Dermatologist-tested, fragrance-free formula with soothing ingredients like Ceramide NP, Panthenol, and Centella extracts. Patch test recommended.

Seafood Allergy Warning

Contains Salmon DNA (PDRN) and Salmon Egg Extract. If you have severe fish allergies, avoid this product or consult a dermatologist first.

03

Ingredient breakdown

INGREDIENTS

Salmon DNA PDRN (Sodium DNA)Trending

Polydeoxyribonucleotide derived from salmon DNA, structurally similar to human DNA. Supports skin cell regeneration, barrier repair, and elasticity improvement.

  • Clinical Study: 33% improvement in skin elasticity after 2 weeks of use
  • Mechanism: Stimulates fibroblast activity and collagen synthesis
  • Biocompatibility: High compatibility with human skin cells due to structural similarity
Most PDRN research is on injectable forms. Topical absorption is limited due to molecular size, but encapsulation technology may enhance delivery.

Niacinamide High %Proven

Vitamin B3 derivative that brightens skin tone, minimizes pores, strengthens skin barrier, and regulates sebum production.

  • Research: Proven to reduce hyperpigmentation and improve skin texture
  • Concentration: Listed 3rd in ingredients, indicating significant concentration
  • Compatibility: Works well with most ingredients including peptides and hyaluronic acid
Safe for all skin types including sensitive skin. Can be used alongside retinol and vitamin C.

Multi-Weight Hyaluronic Acid Complex 6 TypesProven

Includes Sodium Hyaluronate, Hydrolyzed HA, Hydroxypropyltrimonium HA, Sodium Acetylated HA, and Hydrolyzed Sodium HA for comprehensive hydration.

  • Clinical Result: 102.4% improvement in hydration immediately after use
  • Multi-molecular: Different weights penetrate various skin layers
  • Mechanism: Attracts and holds up to 1000x its weight in water

Peptide Complex 5 TypesPromising

Acetyl Hexapeptide-8 (Argireline), Copper Tripeptide-1 (GHK-Cu), Palmitoyl Pentapeptide-4 (Matrixyl), and Palmitoyl Hexapeptide-12 for anti-aging benefits.

  • Argireline: Nicknamed "Botox in a bottle" — relaxes expression lines
  • Copper Peptide: Promotes wound healing and collagen remodeling
  • Matrixyl: Stimulates collagen and elastin production

Ceramide NPProven

Essential lipid that helps restore and maintain the skin's natural barrier, preventing moisture loss and protecting against environmental stressors.

  • Function: Fills gaps between skin cells to strengthen barrier
  • Research: Clinically proven to improve skin barrier function

52 ingredients

Water, Glycerin, Niacinamide, Methylpropanediol, Propanediol, 1,2-Hexanediol, Dipropylene Glycol, Caprylic/Capric Triglyceride, Glycereth-26, Arginine, Butylene Glycol, Ethylhexyl Palmitate, Cetearyl Alcohol, Carbomer, Cetearyl Olivate, Sorbitan Olivate, Ammonium Acryloyldimethyltaurate/VP Copolymer, Simethicone, Eclipta Prostrata Extract, Ethylhexylglycerin, Adenosine, Polyacrylate-13, Sodium DNA, Disodium EDTA, Melia Azadirachta Leaf Extract, Polyisobutene, Hydrolyzed Sclerotium Gum, Glyceryl Stearate, Moringa Oleifera Seed Oil, Polysorbate 20, Sorbitan Isostearate, Sodium Hyaluronate, Glutathione, Octyldodecanol, Hydroxypropyltrimonium Hyaluronate, Salmon Egg Extract, Hydrogenated Lecithin, Ceramide NP, Cyanocobalamin, Thioctic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Collagen Extract, Sodium Acetylated Hyaluronate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hyaluronic Acid, Caprylyl Glycol, Palmitoyl Pentapeptide-4, Hydrolyzed Sodium Hyaluronate, Palmitoyl Hexapeptide-12, Sodium Ascorbyl Phosphate

FREE FROM: Parabens, Artificial Fragrance, Harsh Alcohols, Sulfates, Mineral Oil, Artificial Colors, Gluten, Retinoids, Essential Oils
04

Where it fits in your routine

ROUTINE
1
Cleanser
2
Toner
3
Essence
4
Serum
5
This Cream
6
Sunscreen (AM)

Apply morning and evening as your final moisturizing step. In the morning, always follow with sunscreen.

05

How to use

HOW TO USE
1

Customize Your Mix

Scoop out desired amount and mix the pink capsules with clear gel. For oily skin: more gel (2:1). For dry skin: more capsules (1:2). For normal/combo: equal parts (1:1).

2

Apply to Clean Skin

After cleansing, toning, and applying any serums, gently massage the cream mixture onto face and neck using upward motions.

3

Press & Absorb

Gently press palms against skin to help absorption. The lightweight formula absorbs within 30 seconds without sticky residue.

4

Follow with SPF (AM)

In the morning, always follow with broad-spectrum sunscreen SPF 30+ to protect skin and prevent pigmentation.

06

Who is it for?

WHO

Perfect for you if:

  • You want to achieve "glass skin" glow
  • You're concerned about loss of elasticity and firmness
  • You have uneven skin tone or dullness
  • You prefer lightweight, non-greasy moisturizers
  • You enjoy customizable skincare textures
  • You're looking for anti-aging benefits without retinol
  • You have normal, dry, oily, or combination skin

Consider alternatives if:

  • You have fungal acne (malassezia folliculitis)
  • You have a severe fish or seafood allergy
  • You prefer very rich, heavy creams for extremely dry skin
  • You're looking for a simple, minimal ingredient formula
  • You're pregnant or breastfeeding (consult doctor first)
  • You need a water-free or FA-safe formula
07

Skin type compatibility

SKIN TYPES
Oily Skin
Excellent

Lightweight gel texture absorbs quickly without adding shine. Use more gel than capsules for a lighter, mattifying finish.

Dry Skin
Good

Provides excellent hydration with 6 types of HA. Use more capsules for richer moisture. May need heavier occlusive in winter.

Combination Skin
Excellent

Customizable ratio allows you to adjust for different zones. Perfect for balancing hydration across T-zone and cheeks.

Sensitive Skin
Good

Fragrance-free, dermatologist-tested with soothing ceramides. Patch test recommended for very reactive skin.

Acne-Prone Skin
Moderate

Non-comedogenic and lightweight, but NOT fungal acne safe. Good for regular acne-prone skin, avoid if you have malassezia.

08

Results timeline

4-8 WEEKS
Immediately

Instant Hydration Boost

Skin feels immediately plumped, moisturized, and has a dewy glass-skin glow. Lightweight formula absorbs without residue.

102.4% hydration increase (clinical study)
1-2 Weeks

Improved Skin Texture & Tone

Noticeable improvement in skin smoothness, reduced dullness, and more even skin tone. Skin feels softer and more radiant.

19.4% improvement in uneven skin tone
2-4 Weeks

Enhanced Elasticity & Firmness

Visible improvement in skin elasticity and bounce. Fine lines appear softened, and skin looks plumper and more youthful.

33% improvement in skin elasticity
4-8 Weeks

Cumulative Anti-Aging Benefits

Continued improvement in overall skin health, barrier function, and radiance. Pigmentation continues to fade with consistent use.

Best results with continued daily use
09

Ratings by platform

4K+ REVIEWS
Amazon
4.5
Rating
500+
Reviews
Main complaint: Some users find the jar size small for the price point
YesStyle
4.6
Rating
1,400+
Reviews
Main complaint: Capsules can be slightly uneven in distribution
Ulta Beauty
4.4
Rating
100+
Reviews
Main complaint: May not be hydrating enough alone for very dry skin
Olive Young
4.7
Rating
2,000+
Reviews
Main complaint: Ships internationally which may extend delivery time
10

Pros & cons

BALANCED

Praised

  • Instant glass-skin glow and dewy finish
  • Clinically proven hydration (102.4% increase)
  • Lightweight, non-greasy absorption
  • Customizable texture for all skin types
  • Visible improvement in elasticity within 2 weeks
  • Fragrance-free and gentle formula
  • Fun, unique capsule texture experience
  • Works well under makeup

Criticized

  • Not fungal acne safe
  • 55g jar may run out quickly with 2x daily use
  • Contains fish-derived ingredients (allergen concern)
  • May need additional moisturizer for very dry skin
  • PDRN research mostly on injectables, not topicals
  • Jar packaging less hygienic than pump
11

Budget-friendly alternatives (dupes)

DUPES
85% Match
PDRN Hyaluronic Acid 100 Moisturizing Cream
$22-26
Similar Price

Also features PDRN and hyaluronic acid complex. Squalane-forward formula. More hydrating but without the capsule texture. Fungal acne friendly version available.

70% Match
Advanced Snail 92 All In One Cream
$15-18
Budget Pick

Uses snail mucin instead of PDRN for regeneration. Similar lightweight texture and glass-skin finish. More affordable but different hero ingredient.

65% Match
PDRN Collagen Cream
$20-24
Vegan Option

Plant-based PDRN derived from rice instead of salmon. Great for those avoiding animal-derived ingredients. Contains rice ferment for added brightening.

55% Match
Natural Moisturizing Factors + HA
$8-10
Budget Pick

Simple, barrier-supporting moisturizer with amino acids and HA. No PDRN or anti-aging peptides, but excellent basic hydration at fraction of price.

12

Comparison with competitors

SIDE-BY-SIDE
Hyaluronic Acid Cream
Key Ingredient PDRN + 10 Types HA
Size 60ml
Texture Lightweight Gel-Cream
Fungal Acne Safe Yes (some versions)
Clinical Backing Yes
Cica Cream
Key Ingredient Ginseng PDRN + Cica
Size 50ml
Texture Rich Cream
Fungal Acne Safe No
Clinical Backing Yes
Advanced Snail 92 All In One Cream
Key Ingredient 92% Snail Mucin
Size 100g
Texture Gel-Cream
Fungal Acne Safe No
Clinical Backing Limited
13

Storage & shelf life

12 MONTHS
Period After Opening (PAO)

12 months after opening. Use within one year for best efficacy.

Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required but can extend freshness.

Packaging

Glass jar with screw-top lid. Capsules are suspended in clear gel base. Use clean spatula to maintain hygiene.

Travel Friendly

Yes, 55g is under 100ml TSA limit. Glass jar is sturdy but consider decanting for longer trips.

13

Frequently asked questions

FAQ

Proceed with caution. While this cream doesn't contain known pregnancy-unsafe ingredients like retinoids, salicylic acid, or hydroquinone, there is limited research on topical PDRN use during pregnancy and breastfeeding. Some experts consider it likely safe as PDRN is similar to DNA-based products already available, but we recommend consulting your healthcare provider before use during pregnancy or while nursing.

No, this cream is NOT fungal acne safe. It contains several ingredients that can feed malassezia yeast, including Ethylhexyl Palmitate (a fatty acid ester), Polysorbate 20, Cetearyl Olivate, Sorbitan Olivate (olive-derived emulsifiers), and Moringa Oleifera Seed Oil. If you have fungal acne or are prone to malassezia folliculitis, consider the Anua PDRN line which has fungal acne safe options.

Yes! This cream is compatible with most active ingredients. Niacinamide works well with vitamin C despite old myths. Peptides and PDRN are gentle enough to use alongside retinol. If using retinol, apply retinol first, wait a few minutes, then apply this cream to buffer and hydrate. For AHA/BHA, use them in a different step (like toner) and follow with this cream to soothe and hydrate.

This cream works excellently for oily, combination, and normal skin types due to its lightweight, customizable texture. It's also good for dry skin when using more capsules, though very dry skin may need an additional occlusive layer. Sensitive skin usually tolerates it well (fragrance-free, dermatologist-tested), but patch test first. Not ideal for fungal acne-prone skin.

Hydration benefits are immediate — clinical studies show 102.4% hydration increase right after application. Within 1-2 weeks, expect improved skin texture and 19.4% improvement in skin tone. By 2-4 weeks, clinical studies show 33% improvement in skin elasticity. For best cumulative anti-aging results, use consistently for 4-8 weeks.

Apply as the last step of your skincare routine, after cleanser, toner, essence, and serum. In the morning, follow with sunscreen as the final step. At night, this can be your final step, or you can add a sleeping mask on top for extra hydration. Apply to face and neck morning and evening.

This cream is marketed as non-comedogenic and is dermatologist-tested. We rate it 2/5 on the comedogenic scale — low to moderate risk. While it contains some potentially comedogenic ingredients like Cetearyl Alcohol and Ethylhexyl Palmitate, the overall formula is lightweight and designed not to clog pores. Most users with oily/acne-prone skin report no issues, but individual results may vary.

The Period After Opening (PAO) is 12 months. Use within one year of opening for best results. With the 55g jar used twice daily (AM and PM), most users report it lasts 6-8 weeks depending on how much product they use per application. Store in a cool, dry place and use a clean spatula to maintain hygiene and extend product life.

— Skincarisma verdict
4.5 / 5 ★★★★★

Verdict: The Medicube PDRN Pink Collagen Capsule Cream delivers on its glass-skin promises with clinically proven hydration and elasticity benefits. The unique dual-texture formula is genuinely fun to use and allows customization for different skin needs. While PDRN is still an emerging ingredient in topical skincare, the combination with proven actives like niacinamide, peptides, and multiple hyaluronic acids makes this a well-rounded anti-aging moisturizer. The main drawbacks are that it's not fungal acne safe and the jar packaging could be more hygienic. Overall, an excellent choice for those seeking lightweight, hydrating, K-beauty innovation with visible results.

Product Overview

question
lightbulb What are Quick Product Notes?

Quick product notes are a great way to check if a product is free from commonly avoided ingredients by skincare enthusiasts. These preferences come about for different reasons depending on the ingredient such as personal experiences, sensitivities, health preferences & etc.

muscle Pro Tip Alert!

Just because a product is not free from a common preference does not mean it's a bad product! You can make a personal decision whether or not you want to use a product that contains these ingredients or not - click the labels of the preference to read more about them.

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Quick Product Notes

Click on icons for more information
question
lightbulb What are Notable Effects & Ingredients?

Ever used a product that promised a certain effect but provided no results? It might not have contained any notable ingredients that could have been responsible for that promised effect. It doesn't matter what the marketing or packaging «promises» it can do, if it doesn't contain anything that can help - then the likelihood of it helping is low.

We help you identify key notable ingredients that have been shown to help with effects such as acne-fighting, brightening, UV-protection, wound healing & anti-aging to help you achieve your skincare goals smarter. Please note that different notable ingredients have varying levels of research behind them, some are extremely well proven yet some have mixed research in their efficacy.

muscle Pro Tip Alert!

Just because a product doesn't contain any notable ingredients doesn't mean it's bad. And a product with notable ingredients (or even many) doesn't necessarily guarantee the efficacy of the product performing these effects either. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine this.

Be smart and use this as just a starting point for you to make more informed and smarter choices and compare it with reviews to see if the product is right for you

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Notable Effects & Ingredients

anti-aging Anti-Aging from 10 ingredient(s):
Niacinamide Adenosine Sodium DNA Ceramide NP Hydrolyzed Hyaluronic Acid Hydrolyzed Collagen Extract Acetyl Hexapeptide-8 Copper Tripeptide-1 Hyaluronic Acid Palmitoyl Pentapeptide-4
brightening Brightening from 5 ingredient(s):
Glycerin Niacinamide Glutathione Hydrolyzed Hyaluronic Acid Hyaluronic Acid
wound Promotes Wound Healing from 10 ingredient(s):
Glycerin Niacinamide Arginine Adenosine Sodium Hyaluronate Thioctic Acid Hydrolyzed Hyaluronic Acid Copper Tripeptide-1 Hyaluronic Acid Hydrolyzed Sodium Hyaluronate
ache Ache-fighting from 1 ingredient(s):
Niacinamide
question
lightbulb What are Ingredients Related to Skin Type?

Why are some products great for some people and horrible for others? Well everyone has different skin types and different reactions to the same ingredients.

We've identified a range of ingredients that are commonly regarded as potentially good or bad for those with Dry, Oily/Acne-Prone or Sensitive skin.

muscle Pro Tip Alert!

A product that contains good or bad ingredients for your skin type doesn't always flat out make the entire product good or bad for your skin. There are other factors such as ingredient quality, concentration and formulation that will ultimately determine your skins reaction.

One of the best ways to use this section is to troubleshoot products you've had bad experiences with in the past. Check if it contains any of the marked ingredients to point out suspect ingredients to avoid in the future!

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Ingredients Related to Skin Types

Click on icons for more information
dry-skin Dry Skin
3
oily-skin Oily/Acne-Prone Skin
1
sensitive-skin Sensitive Skin
question
lightbulb What is the Ingredient Safety Breakdown?

Ingredient Safety Breakdown refers to the percentage % of ingredients in different risk categories as classified by EWG (Environment Working Group) if they are available. There are almost endless cosmetic ingredients and they are one of the few organisations globally that have assigned ratings to a lot of the more commonly used ingredients which is why we reference them.

muscle Pro Tip Alert!

EWG is seen by many to be more on the alarmist side in their assignment of health ratings resulting in rating ingredients as riskier than they actually are. We recommend using this a reference point rather than a strict guide of ingredient safety and to always do further research if into ingredients that you may find suspect.

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Ingredient Safety Breakdown

EWG Health Ratings
Low risk
Medium risk
High risk
Unknown risk
67% 1% 30%

Product ingredient list

Showing first 5 of 52 ingredients
EWG CIR Ingredient Name & Cosmetic Functions Notes
1 Unknown
Water
Solvent, Skin Conditioning
2 A
Glycerin
Solvent, Perfuming, Fragrance, Humectant, Viscosity Decreasing Agent, Hair Conditioning, Skin Protecting, Denaturant, Skin Conditioning
brightening Brightening
Promotes Wound Healing
Hydrating
1 A
Niacinamide
Skin Conditioning, Hair Conditioning, Smoothing
brightening Brightening
ache Ache-fighting
anti-aging Anti-Aging
Promotes Wound Healing
Redness
Irritation
Dark Spots
Pores
1 Unknown
Methylpropanediol
Solvent
1 Unknown
Propanediol
Solvent, Viscosity Controlling, Viscosity Decreasing Agent
VIEW ALL INGREDIENTS