NMN Executive Key Serum

12Cosme

Where to buy Possibly in stock

About this product

The 12Cosme NMN Executive Key Serum is a serums, essence, ampoule. Our analysis of its 26 ingredients (16 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
26
Low-risk
16
Fragrance
Fragrance-free
Origin
Japan
Data updated
May 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 5/3
Good for dry skin
Caprylic/Capric Triglyceride Butylene Glycol Glycerin Propylene Glycol PEG-20
Caution for dry skin
Glycerin Polyglyceryl-10 Laurate PEG-40 Hydrogenated Castor Oil
Oily/Acne-Prone Skin No data
Sensitive Skin 3/6
Good for sensitive skin
Resveratrol Glycerin Alaria Esculenta Extract
Caution for sensitive skin
Caprylic/Capric Triglyceride Butylene Glycol Glycerin Propylene Glycol PEG-40 Hydrogenated Castor Oil Phenoxyethanol

Ingredients list

26 total
Lower hazard (1) Higher hazard (4)
All26 Skin Conditioning16 Solvent8 Fragrance8 Humectant6 Skin Protecting5 Perfuming4 Antioxidant3 Viscosity Controlling3
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
B
Polyglyceryl-10 Laurate
(Skin Conditioning, Emulsifying, Surfactant)
Nicotinamide Mononucleotide
(Antioxidant)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
Kappaphycus Alvarezii Extract
(Skin Conditioning)
Caesalpinia Spinosa Fruit Extract
(Skin Protecting)
1
Resveratrol
(Antioxidant, Skin Protecting)
Lactobacillus
(Skin Conditioning)
ASCORBIC ACID
(Antioxidant, Buffering, Fragrance, Skin Conditioning)
glycyrrhiza glabra root extract
(Bleaching, Perfuming, Skin Conditioning, Skin Conditioning Emollient, Smoothing, Soothing)
Alaria Esculenta Extract
(Hair Conditioning, Skin Protecting)
citrus aurantium dulcis peel oil
(Fragrance, Skin Conditioning)
Salvia Officinalis Oil
(Fragrance, Tonic)
1
A
Phospholipids
(Skin Conditioning)
3
B
Potassium Hydroxide
(Ph Adjuster, Buffering Agent)
1
A
Pentasodium Pentetate
(Chelating Agent)
3
B
PEG-40 Hydrogenated Castor Oil
(Fragrance, Emulsifying, Surfactant, Perfuming)
Fungal Acne
Fungal Acne Trigger
1
A
Pentylene Glycol
(Skin Conditioning, Solvent)
1
A
1,2-Hexanediol
(Solvent)
3
A
PEG-20
(Humectant, Solvent)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
3
B
Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
Vitamin C
Brightens, evens tone, and supports collagen.
Niacinamide
Strengthens, smooths, and brightens skin.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
BrighteningRestores radiance to dull, tired skin.
Scar HealingImproves the look of marks and scars.
Anti-AgingSoftens lines and helps skin look youthful.
Reduces IrritationEases discomfort and supports skin resilience.
Redness ReducingSoothes visible redness and calms irritation.
Dark SpotsFades dark spots for even skin tone.

Concerns

Contains paraben
Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Polyglyceryl-10 Laurate
Skin conditioning, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmulsifyingSurfactant
Nicotinamide Mononucleotide
Antioxidant
Limited public safety data.Read moreShow less
EWG N/A Antioxidant
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Kappaphycus Alvarezii Extract
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Caesalpinia Spinosa Fruit Extract
Skin protecting
Limited public safety data.Read moreShow less
EWG N/A Skin protecting
Resveratrol
Antioxidant, Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin protecting
Lactobacillus
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
ASCORBIC ACID
Antioxidant, Buffering
Limited public safety data.Read moreShow less
EWG N/A AntioxidantBufferingFragranceSkin conditioning
glycyrrhiza glabra root extract
Bleaching, Perfuming
Limited public safety data.Read moreShow less
EWG N/A BleachingPerfumingSkin conditioningSkin conditioning emollientSmoothingSoothing
Alaria Esculenta Extract
Hair conditioning, Skin protecting
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningSkin protecting
citrus aurantium dulcis peel oil
Fragrance, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A FragranceSkin conditioning
Salvia Officinalis Oil
Fragrance, Tonic
Limited public safety data.Read moreShow less
EWG N/A FragranceTonic
Phospholipids
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Potassium Hydroxide
Ph adjuster, Buffering agent
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B Ph adjusterBuffering agent
+ 6 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
PEG-40 Hydrogenated Castor Oil
Fragrance, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceEmulsifyingSurfactantPerfuming Fungal-acne trigger
Propylene Glycol
Fragrance, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceHumectantSkin-conditioningagent - miscellaneousSolventViscosity decreasing agentSkin conditioningViscosity controlling Good for Dry Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning works well: Antioxidants like vitamin C pair well with daytime use under sunscreen.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

ASCORBIC ACID

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Nicotinamide Mononucleotide, Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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