R45 The Reversal 3-Phase Retinol Booster System

BeautyBio

R45 The Reversal 3-Phase Retinol Booster System

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About this product

The BeautyBio R45 The Reversal 3-Phase Retinol Booster System is a treatment. Our analysis of its 34 ingredients (27 low-risk) rates it Excellent (93/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Treatments
Ingredients
34
Low-risk
27
Fragrance
Fragrance-free
Origin
United States
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 10/9
Good for dry skin
Dimethiconol Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Glycerin Propylene Glycol Cocoglycerides Dimethicone Cyclopentasiloxane Sodium Polyacrylate
Caution for dry skin
Dimethicone Crosspolymer Lysolecithin Glycerin Trideceth-6 Polyglyceryl-10 Laurate Sodium Polyacrylate Polysorbate 60 PEG-12 Dimethicone Crosspolymer Disodium EDTA-Copper
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Retinol Disodium EDTA-Copper
Sensitive Skin 4/8
Good for sensitive skin
Glycerin Dimethicone Tocopheryl Acetate BHT
Caution for sensitive skin
Dipropylene Glycol Butylene Glycol Glycerin Propylene Glycol Citric Acid Phenoxyethanol BHT Retinol

Ingredients list

34 total
Lower hazard (1) Higher hazard (9)
All34 Skin Conditioning23 Solvent7 Emulsifying7 Fragrance7 Viscosity Controlling7 Humectant7 Emulsion Stabilising6 Emollient5
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
Safflower Acid
(Cleansing, Surfactant Cleansing)
1
A
Cocoglycerides
(Skin Conditioning, Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
Safflower Glyceride
(Skin Conditioning Emollient, Surfactant Cleansing, Surfactant Emulsifying)
Glyceryl Diretinoate
(Skin Conditioning)
1
A
Lysolecithin
(Emulsifying, Surfactant)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
Acetyl Carboxymethyl Cocoyl Glycine
(Chelating)
1
B
Polyglyceryl-10 Laurate
(Skin Conditioning, Emulsifying, Surfactant)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
6
A
BHT
(Antioxidant, Fragrance, Masking)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling)
3
B
Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
3
A
Cyclopentasiloxane
(Hair Conditioning, Skin Conditioning, Emollient, Solvent)
Silicone
Silicone
3
PEG-12 Dimethicone Crosspolymer
(Emulsion Stabilising, Emulsifying, Surfactant, Suspending Agent Nonsurfactant, Viscosity Increasing Agent, Stabilising, Viscosity Controlling)
1
A
Dimethicone Crosspolymer
(Emulsion Stabilising, Hair Fixing, Suspending Agent Nonsurfactant, Viscosity Increasingagent Nonaqueous, Viscosity Controlling)
1
A
Dimethicone/Vinyl Dimethicone Crosspolymer
(Viscosity Controlling)
1
A
Dimethiconol
(Antifoaming Agent, Skin Conditioning, Emollient, Moisturising)
Silicone
Silicone
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
Pentylene Glycol
(Skin Conditioning, Solvent)
1
Hydroxyphenyl Propamidobenzoic Acid
(Skin Conditioning)
1
Myristoyl Pentapeptide-17
(Skin Conditioning)
3
B
Sodium Polyacrylate
(Absorbent, Emulsion Stabilising, Film Forming, Hair Fixing, Skin Conditioning Agent Emollient, Viscosity Controlling Agent, Viscosity Increasing Agent, Binding, Skin Conditioning)
1
B
Trideceth-6
(Emulsifying, Surfactant)
3
B
Polysorbate 60
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
3
A
PEG/PPG-18/18 Dimethicone
(Emulsifying)
1
4
Disodium EDTA-Copper
(Cosmetic Colorant, Astringent, Chelating)
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Retinoid
Visibly reduces the signs of aging.
Antioxidants
Shields skin from free radical damage.
Vitamin E
Protects skin and soothes irritation.
Hyaluronic Acid
Hydrates by attracting and holding water.
Peptides
Supports skin hydration and improves firmness.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Scar HealingImproves the look of marks and scars.
Anti-AgingSoftens lines and helps skin look youthful.
BrighteningRestores radiance to dull, tired skin.
Acne FightingFights acne and helps prevent breakouts.
Good For Oily SkinBalances oil and helps reduce shine.
Reduces Large PoresMinimizes the look of enlarged pores.

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Safflower Acid
Cleansing, Surfactant cleansing
Limited public safety data.Read moreShow less
EWG N/A CleansingSurfactant cleansing
Safflower Glyceride
Skin conditioning emollient, Surfactant cleansing
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning emollientSurfactant cleansingSurfactant emulsifying
Glyceryl Diretinoate
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Lysolecithin
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion stabilising, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 Emulsion stabilisingFilm formingViscosity controlling
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
Acetyl Carboxymethyl Cocoyl Glycine
Chelating
Low-hazard ingredient.Read moreShow less
EWG 1 Chelating
Polyglyceryl-10 Laurate
Skin conditioning, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmulsifyingSurfactant
Dipropylene Glycol
Fragrance, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSolventViscosity decreasing agentMaskingViscosity controlling
PEG-12 Dimethicone Crosspolymer
Emulsion stabilising, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 3 Emulsion stabilisingEmulsifyingSurfactantSuspending agent - nonsurfactantViscosity increasing agentStabilisingViscosity controlling
Dimethicone Crosspolymer
Emulsion stabilising, Hair fixing
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingHair fixingSuspending agent - nonsurfactantViscosity increasingagent - nonaqueousViscosity controlling
Dimethicone/Vinyl Dimethicone Crosspolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Viscosity controlling
Pentylene Glycol
Skin conditioning, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningSolvent
Hydroxyphenyl Propamidobenzoic Acid
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
+ 5 more — see the full ingredients list above
Cocoglycerides
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmollientEmulsifying Fungal-acne trigger
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin
BHT
Antioxidant, Fragrance
Moderate-hazard ingredient.Read moreShow less
EWG 6 CIR A AntioxidantFragranceMasking
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Propylene Glycol
Fragrance, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceHumectantSkin-conditioningagent - miscellaneousSolventViscosity decreasing agentSkin conditioningViscosity controlling Good for Dry Skin
Cyclopentasiloxane
Hair conditioning, Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Hair conditioningSkin conditioningEmollientSolvent Silicone
Dimethiconol
Antifoaming agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antifoaming agentSkin conditioningEmollientMoisturising Silicone
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Polysorbate 60
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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