Squalane + Retinol Night Serum

Biossance

Where to buy Possibly in stock

About this product

The Biossance Squalane + Retinol Night Serum is a serums, essence, ampoule. Our analysis of its 23 ingredients (14 low-risk) rates it Excellent (92/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
23
Low-risk
14
Fragrance
Fragrance-free
Origin
United States
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 4/4
Good for dry skin
Cetearyl Alcohol Squalane Caprylic/Capric Triglyceride Glycerin
Caution for dry skin
Dextrin Sorbitan Olivate Glycerin Sodium Hydroxide
Oily/Acne-Prone Skin 1/0
Good for oily/acne-prone skin
Retinol
Sensitive Skin 2/4
Good for sensitive skin
Glycerin Allantoin
Caution for sensitive skin
Caprylic/Capric Triglyceride Glycerin Phenoxyethanol Retinol

Ingredients list

23 total
Lower hazard (1) Higher hazard (9)
All23 Skin Conditioning17 Emulsion Stabilising5 Hair Conditioning4 Skin Protecting4 Fragrance4 Viscosity Increasing Agent3 Viscosity Controlling3 Emollient3
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
B
Cetearyl Olivate
(Hair Conditioning)
1
A
Sorbitan Olivate
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
5
6
Retinal
(Skin Conditioning)
1
A
Allantoin
(Skin Conditioning, Skin Protecting, Soothing)
Good for Oily Skin
Good for Oily Skin
Good for Sensitive Skin
Good for Sensitive Skin
Crocus Sativus Stigma Extract
(Skin Conditioning)
Pseudozyma Epicola/Evening Primrose Oil Ferment Extract
(Skin Conditioning, Skin Conditioning Emollient)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
rosmarinus officinalis leaf extract
(Antimicrobial, Fragrance, Skin Conditioning)
Oryza Sativa Bran Extract
(Skin Conditioning, Skin Protecting)
1
A
Cetearyl Alcohol
(Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling)
Helianthus Annuus Extract
(Hair Conditioning, Skin Conditioning, Skin Conditioning Emollient)
1
Hydroxyapatite
(Abrasive, Bulking Agent, Oral Care Agent, Emulsion Stabilising)
1
A
Dextrin
(Absorbent, Binding Agent, Bulking Agent, Viscosity Increasing Agent, Binding, Viscosity Controlling)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
1
A
Sodium Gluconate
(Chelating Agent, Skin Conditioning)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

Browse similar serums, essence, ampoule
No close formula match yet — browse other products like this

Key ingredients

Retinoid
Visibly reduces the signs of aging.
Vitamin E
Protects skin and soothes irritation.
Antioxidants
Shields skin from free radical damage.
Exfoliators
Removes dead skin cells to smoothe texture.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Anti-AgingSoftens lines and helps skin look youthful.
Scar HealingImproves the look of marks and scars.
BrighteningRestores radiance to dull, tired skin.
Good For Oily SkinBalances oil and helps reduce shine.
Dark SpotsFades dark spots for even skin tone.
Acne FightingFights acne and helps prevent breakouts.

Concerns

Contains paraben
Not fungal acne (malassezia) safe
Retinol — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Cetearyl Olivate
Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioning
Crocus Sativus Stigma Extract
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Pseudozyma Epicola/Evening Primrose Oil Ferment Extract
Skin conditioning, Skin conditioning emollient
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningSkin conditioning emollient
TOCOPHEROL
Antioxidant, Fragrance
Limited public safety data.Read moreShow less
EWG N/A AntioxidantFragranceSkin conditioning
rosmarinus officinalis leaf extract
Antimicrobial, Fragrance
Limited public safety data.Read moreShow less
EWG N/A AntimicrobialFragranceSkin conditioning
Oryza Sativa Bran Extract
Skin conditioning, Skin protecting
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningSkin protecting
Cetearyl Alcohol
Emulsion stabilising, Opacifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingOpacifyingFoam boostingViscosity increasingagent - aqueousViscosity increasing agentEmollientEmulsifyingViscosity controlling
Helianthus Annuus Extract
Hair conditioning, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningSkin conditioningSkin conditioning emollient
Hydroxyapatite
Abrasive, Bulking agent
Low-hazard ingredient.Read moreShow less
EWG 1 AbrasiveBulking agentOral care agentEmulsion stabilising
Dextrin
Absorbent, Binding agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A AbsorbentBinding agentBulking agentViscosity increasing agentBindingViscosity controlling
Carbomer
Emulsion stabilising, Viscosity increasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingViscosity increasing agentGel formingViscosity controlling
Sodium Gluconate
Chelating agent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentSkin conditioning
+ 2 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Sorbitan Olivate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant Fungal-acne trigger
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Retinal
Skin conditioning
Moderate-hazard ingredient.Read moreShow less
EWG 5–6 Skin conditioning
Allantoin
Skin conditioning, Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningSkin protectingSoothing Good for Oily SkinGood for Sensitive Skin
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol, Retinal)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol, Retinal

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

From the community

0
Reviews
0
Saved by users
0
In collections

Ratings & reviews

Write a Review
0.0
from 0 ratings

Used this product? Rate it in 10 seconds

Alternatives