Synactif Cream

Clé de Peau Beauté

Where to buy Possibly in stock

About this product

The Clé de Peau Beauté Synactif Cream is a moisturizer. Our analysis of its 79 ingredients (52 low-risk) rates it Excellent (93/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin. Heads up: it contains fragrance, which can irritate sensitive or reactive skin.

Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Moisturizers
Ingredients
79
Low-risk
52
Fragrance
Contains fragrance
Origin
Japan
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 21/14
Good for dry skin
Honey Betaine Behenyl Alcohol Cetyl Ethylhexanoate Sodium Acetylated Hyaluronate Stearyl Alcohol Erythritol Inositol Panax Ginseng Root Extract Xylitol Butylene Glycol Sodium Hyaluronate Glycerin Triisostearin Polyquaternium-51 Hydrogenated Palm Oil Camellia Sinensis Leaf Extract Dimethicone Petrolatum Lecithin Myristyl Myristate
Caution for dry skin
Glyceryl Stearate SE Sorbitan Tristearate Stearyl Alcohol Isostearic Acid Xanthan Gum Sanguisorba Officinalis Root Extract Glycerin Alcohol Camellia Sinensis Leaf Extract Polysorbate 60 PEG-100 Stearate Silica Lecithin Uncaria Gambir Extract
Oily/Acne-Prone Skin 3/1
Good for oily/acne-prone skin
Alcohol Camellia Sinensis Leaf Extract Uncaria Gambir Extract
Caution for oily/acne-prone skin
Petrolatum
Sensitive Skin 10/18
Good for sensitive skin
Melia Azadirachta Leaf Extract Panax Ginseng Root Extract Glycerin Camellia Sinensis Leaf Extract Dimethicone Tocopheryl Acetate Allantoin Sodium Metabisulfite Petrolatum BHT
Caution for sensitive skin
Dipropylene Glycol Sodium Citrate Stearyl Alcohol Butylene Glycol Glycerin Pinus Sylvestris Cone Extract Citric Acid Alcohol Camellia Sinensis Leaf Extract Sodium Benzoate Phenoxyethanol Linalool Citronellol BHT Butylphenyl Methylpropional Geraniol Retinyl Acetate Cinnamomum Cassia Bark Extract

Ingredients list

79 total
Lower hazard (1) Higher hazard (9)
All79 Skin Conditioning45 Fragrance16 Humectant16 Masking14 Emollient12 Viscosity Controlling11 Hair Conditioning10 Skin Protecting9
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Triisostearin
(Viscosity Increasing Agent, Emollient, Skin Conditioning, Solvent, Viscosity Controlling)
limnanthes alba seed oil
(Skin Conditioning)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
4
Petrolatum
(Hair Conditioning, Skin Conditioning Agent Occlusive, Skin Protecting, Emollient, Moisturising, Uv Absorber)
Bad for Oily Skin
Bad for Oily Skin
1
A
Phytosteryl Macadamiate
(Hair Conditioning, Skin Conditioning)
1
B
Betaine
(Hair Conditioning, Humectant, Antistatic Agent, Skin Conditioning, Viscosity Controlling)
1
A
Behenyl Alcohol
(Binding Agent, Emulsion Stabilising, Viscosity Increasing Agent, Binding, Emollient, Viscosity Controlling)
1
A
Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling)
1
B
Cetyl Ethylhexanoate
(Skin Conditioning, Emollient)
2
3
B
Myristyl Myristate
(Emollient, Opacifying, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
Erythritol
(Humectant, Moisturising)
3
B
PEG/PPG-14/7 Dimethyl Ether
(Skin Conditioning)
1
A
Glyceryl Stearate SE
(Emulsifying, Surfactant)
Bad for Oily Skin
Bad for Oily Skin
1
Xylitol
(Flavoring Agent, Humectant, Skin Conditioning)
3
A
PEG-100 Stearate
(Surfactant)
Fungal Acne
Fungal Acne Trigger
1
2
A
Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling)
Potassium Methoxysalicylate
(Bleaching)
1
A
Microcrystalline Wax
(Binding, Bulking, Emulsion Stabilising, Viscosity Controlling)
1
A
Stearyl Alcohol
(Emulsion Stabilising, Fragrance, Emulsifying, Surfactant, Foambooster, Viscosity Increasing Agent, Emollient, Foam Boosting, Masking, Opacifying, Refatting, Viscosity Controlling)
Dimethylacrylamide
(Not Reported)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Sorbitan Tristearate
(Emulsifying, Surfactant)
2
A
Hydrogenated Palm Oil
(Viscosity Increasing Agent, Emollient, Emulsifying, Skin Conditioning, Viscosity Controlling)
Elaeis Guineensis Kernel Oil
(Skin Conditioning Emollient)
PARFUM
(Fragrance, Perfuming)
3
B
Polysorbate 60
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
ELAEIS GUINEENSIS OIL
(Skin Conditioning Emollient)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
Diphenylsiloxy Phenyl Trimethicone
(Antifoaming Agent, Hair Conditioning, Skin Conditioning)
1
PPG-17
(Skin Conditioning)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
2-O-Ethyl Ascorbic Acid
(Skin Conditioning)
1
Polyquaternium-51
(Film Forming, Humectant, Skin Conditioning)
1
A
Sodium Citrate
(Ph Adjuster, Buffering Agent, Chelating, Masking)
1
A
Isostearic Acid
(Binding Agent, Sufactantsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Isostearic Acid., Binding, Emulsifying)
Fungal Acne
Fungal Acne Trigger
6
A
BHT
(Antioxidant, Fragrance, Masking)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
3
B
Potassium Hydroxide
(Ph Adjuster, Buffering Agent)
1
B
Sodium Metaphosphate
(Buffering Agent, Chelating Agent, Oral Care Agent)
1
A
Trisodium EDTA
(Chelating Agent)
1
B
Lauryl Betaine
(Antistatic Agent, Hair Conditioning, Skin Conditioning, Sufactant, Foam Boosting, Viscosity Increasing Agent)
7
Butylphenyl Methylpropional
(Perfuming)
Allergens
Allergens
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
4
A
Sodium Metabisulfite
(Antioxidant, Preservative, Reducing)
1
Sodium Acetylated Hyaluronate
(Humectant)
1
CI 77492
(Colorant, Cosmetic Colorant)
5
Linalool
(Fragrance, Deodorant, Masking)
Allergens
Allergens
glycyrrhiza glabra root extract
(Bleaching, Perfuming, Skin Conditioning, Skin Conditioning Emollient, Smoothing, Soothing)
5
Citronellol
(Fragrance, Masking)
Allergens
Allergens
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
7
Geraniol
(Fragrance, Masking, Tonic)
Allergens
Allergens
1
2
CI 77491
(Colorant, Cosmetic Colorant)
Lamium Album Flower/Leaf/Stem Extract
(Skin Conditioning)
1
Morus Alba Root Extract
(Bleaching, Skin Conditioning)
1
Sanguisorba Officinalis Root Extract
(Cleansing, Refreshing, Skin Conditioning, Tonic)
1
Melia Azadirachta Leaf Extract
(Antimicrobial, Skin Protecting)
Rubus Suavissimus Leaf Extract
(Skin Conditioning)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
Inositol
(Antistatic Agent, Hair Conditioning, Humectant)
1
Melissa Officinalis Leaf Extract
(Skin Conditioning)
Cinnamomum Cassia Bark Extract
(Hair Conditioning, Masking, Oral Care Agent)
2
Pinus Sylvestris Cone Extract
(Masking, Perfuming)
2
3
Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient)
9
Retinyl Acetate
(Skin Conditioning)
Retinyl Palmitate
(Skin Conditioning, Skin Conditioning Miscellaneous)
Helianthus Annuus Seed Oil
(Fragrance, Skin Conditioning, Skin Conditioning Emollient)
Zea Mays Oil
(Fragrance, Hair Conditioning, Perfuming, Skin Conditioning, Surfactant Emulsifying)
lavandula angustifolia oil
(Fragrance, Tonic)
1
A
Allantoin
(Skin Conditioning, Skin Protecting, Soothing)
Good for Oily Skin
Good for Oily Skin
Good for Sensitive Skin
Good for Sensitive Skin
1
Honey
(Flavoring Agent, Humectant, Emollient, Moisturising)
3
A
Sodium Benzoate
(Fragrance, Preservative, Anticorrosive, Masking)
1
A
Panax Ginseng Root Extract
(Emollient, Hair Conditioning, Skin Protecting, Tonic)
Uncaria Gambir Extract
(Astringent)
olea europaea leaf extract
(Perfuming, Skin Conditioning)
1
B
Camellia Sinensis Leaf Extract
(Antimicrobial, Antioxidant, Astringent, Emollient, Humectant, Masking, Oral Care Agent, Skin Conditioning, Skin Protecting, Tonic, Uv Absorber)
Good for Oily Skin
Good for Oily Skin
1
Bupleurum Falcatum Root Extract
(Skin Conditioning)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
Retinoid
Visibly reduces the signs of aging.
Vitamin E
Protects skin and soothes irritation.
Hyaluronic Acid
Hydrates by attracting and holding water.
Vitamin C
Brightens, evens tone, and supports collagen.
Exfoliators
Removes dead skin cells to smoothe texture.
Show all 6 key ingredients

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
BrighteningRestores radiance to dull, tired skin.
Scar HealingImproves the look of marks and scars.
Redness ReducingSoothes visible redness and calms irritation.
Reduces IrritationEases discomfort and supports skin resilience.
Anti-AgingSoftens lines and helps skin look youthful.
Dark SpotsFades dark spots for even skin tone.

Concerns

Contains paraben
Contains silicone
Contains eu allergen
Not fungal acne (malassezia) safe
Butylphenyl Methylpropional — higher EWG
Geraniol — higher EWG
Retinyl Acetate — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Triisostearin
Viscosity increasing agent, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Viscosity increasing agentEmollientSkin conditioningSolventViscosity controlling
limnanthes alba seed oil
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
Phytosteryl Macadamiate
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioning
Betaine
Hair conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioningHumectantAntistatic agentSkin conditioningViscosity controlling
Behenyl Alcohol
Binding agent, Emulsion stabilising
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentEmulsion stabilisingViscosity increasing agentBindingEmollientViscosity controlling
Dipropylene Glycol
Fragrance, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSolventViscosity decreasing agentMaskingViscosity controlling
Cetyl Ethylhexanoate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioningEmollient
Erythritol
Humectant, Moisturising
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantMoisturising
PEG/PPG-14/7 Dimethyl Ether
Skin conditioning
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B Skin conditioning
Xylitol
Flavoring agent, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 Flavoring agentHumectantSkin conditioning
Silica
Abrasive, Absorbent
Low-hazard ingredient.Read moreShow less
EWG 1–2 CIR A AbrasiveAbsorbentAnticaking agentBulking agentOpacifyingViscosity controlling
Potassium Methoxysalicylate
Bleaching
Limited public safety data.Read moreShow less
EWG N/A Bleaching
Microcrystalline Wax
Binding, Bulking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A BindingBulkingEmulsion stabilisingViscosity controlling
Stearyl Alcohol
Emulsion stabilising, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingFragranceEmulsifyingSurfactant- foamboosterViscosity increasing agentEmollientFoam boostingMaskingOpacifyingRefattingViscosity controlling
+ 42 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Petrolatum
Hair conditioning, Skin-conditioning agent - occlusive
Potentially comedogenic - can block poresRead moreShow less
EWG 4 Hair conditioningSkin-conditioning agent - occlusiveSkin protectingEmollientMoisturisingUv absorber Bad for Oily Skin
Myristyl Myristate
Emollient, Opacifying
Potentially comedogenic - can block poresRead moreShow less
EWG 2–3 CIR B EmollientOpacifyingSkin conditioning Bad for Oily Skin
Glyceryl Stearate SE
Emulsifying, Surfactant
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A EmulsifyingSurfactant Bad for Oily Skin
PEG-100 Stearate
Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Surfactant Fungal-acne trigger
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Polysorbate 60
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Isostearic Acid
Binding agent, Sufactantsurfactant-cleansing agent is included as a function for the soap form of isostearic acid.
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentSufactantsurfactant-cleansing agent is included as a function for the soap form of isostearic acid.BindingEmulsifying Fungal-acne trigger
BHT
Antioxidant, Fragrance
Moderate-hazard ingredient.Read moreShow less
EWG 6 CIR A AntioxidantFragranceMasking
Butylphenyl Methylpropional
Perfuming
Higher-hazard ingredient.Read moreShow less
EWG 7 Perfuming Allergens
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin
+ 7 more — see the full ingredients list above

How to use

How to use

  • 1 Where it fits: Apply near the end of your routine, after thinner serums.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinyl Acetate, Retinyl Palmitate)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinyl Acetate, Retinyl Palmitate

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

2-O-Ethyl Ascorbic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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