The Defender Peptide Retinol Night Cream

Conscious Chemist

The Defender Peptide Retinol Night Cream

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About this product

The Conscious Chemist The Defender Peptide Retinol Night Cream is a emulsion. Our analysis of its 44 ingredients (29 low-risk) rates it Excellent (93/100). Based on its ingredients, it looks well-suited to oily / acne-prone and dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Emulsion
Ingredients
44
Low-risk
29
Fragrance
Fragrance-free
Origin
India
Data updated
May 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 14/6
Good for dry skin
Glyceryl Stearate Glyceryl Oleate Sclerocarya Birrea Seed Oil Cetearyl Alcohol Isopropyl Myristate Caprylic/Capric Triglyceride Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Propylene Glycol Adansonia Digitata Oil Hydrogenated Polydecene Dimethicone Lecithin
Caution for dry skin
Glyceryl Oleate Lauryl Glucoside Sorbitan Olivate Alcohol Polysorbate 20 Lecithin
Oily/Acne-Prone Skin 2/0
Good for oily/acne-prone skin
Alcohol Retinol
Sensitive Skin 7/12
Good for sensitive skin
Ubiquinone Dimethicone Tocopheryl Acetate Allantoin BHT BHA sh-Oligopeptide-2
Caution for sensitive skin
Glyceryl Oleate Isopropyl Myristate Caffeine Caprylic/Capric Triglyceride Butylene Glycol Propylene Glycol Alcohol Hydrogenated Polydecene Phenoxyethanol BHT Retinol BHA

Ingredients list

44 total
Lower hazard (1) Higher hazard (9)
All44 Skin Conditioning42 Fragrance12 Emollient10 Solvent7 Humectant6 Masking6 Viscosity Controlling6 Emulsifying6
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
3
B
Propylene Glycol
(Fragrance, Humectant, Skin Conditioningagent Miscellaneous, Solvent, Viscosity Decreasing Agent, Skin Conditioning, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
B
Isopropyl Myristate
(Binding Agent, Fragrance, Skin Conditioning, Emollient, Binding, Perfuming, Solvent)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
1
A
Glyceryl Stearate
(Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
1
B
Cetearyl Olivate
(Hair Conditioning)
1
A
Sorbitan Olivate
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Cetearyl Alcohol
(Emulsion Stabilising, Opacifying, Foam Boosting, Viscosity Increasingagent Aqueous, Viscosity Increasing Agent, Emollient, Emulsifying, Viscosity Controlling)
3
A
Dimethicone
(Antifoaming Agent, Skin Protecting, Emollient, Skin Conditioning)
Silicone
Silicone
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
cocos nucifera oil
(Fragrance, Hair Conditioning, Perfuming, Skin Conditioning)
Sodium Acrylates/Beheneth-25 Methacrylate Crosspolymer
(Skin Conditioning, Viscosity Controlling)
2
A
Hydrogenated Polydecene
(Fragrance, Hair Conditioning, Skin Conditioning, Emollient, Solvent)
1
B
Lauryl Glucoside
(Cleansing, Surfactant)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
Helianthus Annuus Seed Oil
(Fragrance, Skin Conditioning, Skin Conditioning Emollient)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Glyceryl Oleate
(Fragrance, Skin Conditioning, Emollient, Emulsifying, Surfactant, Perfuming)
Fungal Acne
Fungal Acne Trigger
glycyrrhiza glabra root extract
(Bleaching, Perfuming, Skin Conditioning, Skin Conditioning Emollient, Smoothing, Soothing)
1
A
Allantoin
(Skin Conditioning, Skin Protecting, Soothing)
Good for Oily Skin
Good for Oily Skin
Good for Sensitive Skin
Good for Sensitive Skin
1
Mauritia Flexuosa Fruit Oil
(Skin Conditioning)
Fungal Acne
Fungal Acne Trigger
9
A
Retinol
(Skin Conditioning)
Bad for Sensitive Skin
Bad for Sensitive Skin
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
5
7
BHA
(Antioxidant, Fragrance, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
2
3
Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient)
1
B
Acetyl Glutamine
(Skin Conditioning)
sh-Oligopeptide-1
(Skin Conditioning)
sh-Oligopeptide-2
(Skin Conditioning, Skin Protecting)
sh-Polypeptide-1
(Skin Conditioning)
sh-Polypeptide-9
(Skin Conditioning)
sh-Polypeptide-11
(Skin Conditioning)
Bacillus/Soybean Ferment Extract
(Skin Conditioning)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
Hexapeptide-11
(Skin Conditioning)
1
Leuconostoc/Radish Root Ferment Filtrate
(Antidandruff Agent, Antimicrobial)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
Bisabolol
(Fragrance, Skin Conditioning, Soothing)
1
Adansonia Digitata Oil
(Emollient, Skin Conditioning)
1
Caffeine
(Fragrance, Skin Conditioning, Masking)
6
A
BHT
(Antioxidant, Fragrance, Masking)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
A
Sclerocarya Birrea Seed Oil
(Hair Conditioning, Humectant)
1
Ubiquinone
(Antioxidant, Skin Conditioning)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Propylene Glycol
Humectant, Skin Conditioning
Isopropyl Myristate
Skin Conditioning, Emollient
Glyceryl Stearate
Emollient
Cetearyl Alcohol
Emollient
Dimethicone
Skin Protecting, Emollient
Caprylic/Capric Triglyceride
Emollient, Skin Conditioning

Benefits

Good for dry skin
Good for oily/acne-prone skin

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe
Retinol — higher EWG
BHA — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Cetearyl Olivate
Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioning
Cetearyl Alcohol
Emulsion stabilising, Opacifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingOpacifyingFoam boostingViscosity increasingagent - aqueousViscosity increasing agentEmollientEmulsifyingViscosity controlling
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
cocos nucifera oil
Fragrance, Hair conditioning
Limited public safety data.Read moreShow less
EWG N/A FragranceHair conditioningPerfumingSkin conditioning
Sodium Acrylates/Beheneth-25 Methacrylate Crosspolymer
Skin conditioning, Viscosity controlling
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningViscosity controlling
Hydrogenated Polydecene
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A FragranceHair conditioningSkin conditioningEmollientSolvent
Lauryl Glucoside
Cleansing, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B CleansingSurfactant
Helianthus Annuus Seed Oil
Fragrance, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A FragranceSkin conditioningSkin conditioning emollient
glycyrrhiza glabra root extract
Bleaching, Perfuming
Limited public safety data.Read moreShow less
EWG N/A BleachingPerfumingSkin conditioningSkin conditioning emollientSmoothingSoothing
Lecithin
Skin conditioning, Emulsifying
Low-to-moderate hazard.Read moreShow less
EWG 2–3 Skin conditioningEmulsifyingSurfactantAntistatic agentEmollient
Acetyl Glutamine
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Skin conditioning
sh-Oligopeptide-1
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
sh-Oligopeptide-2
Skin conditioning, Skin protecting
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningSkin protecting
sh-Polypeptide-1
Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Skin conditioning
+ 12 more — see the full ingredients list above
Propylene Glycol
Fragrance, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B FragranceHumectantSkin-conditioningagent - miscellaneousSolventViscosity decreasing agentSkin conditioningViscosity controlling Good for Dry Skin
Isopropyl Myristate
Binding agent, Fragrance
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR B Binding agentFragranceSkin conditioningEmollientBindingPerfumingSolvent Bad for Oily SkinFungal-acne trigger
Glyceryl Stearate
Emollient, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientEmulsifying Fungal-acne trigger
Sorbitan Olivate
Emulsifying, Surfactant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmulsifyingSurfactant Fungal-acne trigger
Dimethicone
Antifoaming agent, Skin protecting
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Antifoaming agentSkin protectingEmollientSkin conditioning Silicone
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Glyceryl Oleate
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningEmollientEmulsifyingSurfactantPerfuming Fungal-acne trigger
Allantoin
Skin conditioning, Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningSkin protectingSoothing Good for Oily SkinGood for Sensitive Skin
Mauritia Flexuosa Fruit Oil
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning Fungal-acne trigger
Retinol
Skin conditioning
Potentially a skin irritantRead moreShow less
EWG 9 CIR A Skin conditioning Bad for Sensitive Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
BHA
Antioxidant, Fragrance
Higher-hazard ingredient.Read moreShow less
EWG 5–7 AntioxidantFragranceMasking Bad for Sensitive Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
+ 2 more — see the full ingredients list above

How to use

How to use

  • 1 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 2 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinol)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinol

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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