Pepoxide Antioxidant Peptide Concentrate

Cosmedix

Pepoxide Antioxidant Peptide Concentrate

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About this product

The Cosmedix Pepoxide Antioxidant Peptide Concentrate is a serums, essence, ampoule. Our analysis of its 36 ingredients (31 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to oily / acne-prone skin.

Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
36
Low-risk
31
Fragrance
Fragrance-free
Origin
United States
Data updated
May 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 6/8
Good for dry skin
Gluconolactone Mannitol Calcium Gluconate Glycerin Hydrolyzed Collagen Cupressus Sempervirens Leaf/Nut/Stem Oil
Caution for dry skin
Dextrin Xanthan Gum Glycerin Polygonum Cuspidatum Extract Alcohol Sodium Hydroxide Polysorbate 20 Alcohol Denat.
Oily/Acne-Prone Skin 3/0
Good for oily/acne-prone skin
Polygonum Cuspidatum Extract Alcohol Alcohol Denat.
Sensitive Skin 6/14
Good for sensitive skin
Superoxide Dismutase Glycerin Quercetin Totarol Phenyl t-Butylnitrone Ferulic Acid
Caution for sensitive skin
Gluconolactone Glutathione Mannitol Sodium Citrate Acetyl Tributyl Citrate Caffeine Glycerin Citric Acid Alcohol Isopropyl Alcohol Sodium Benzoate Potassium Sorbate Alcohol Denat. Cupressus Sempervirens Leaf/Nut/Stem Oil

Ingredients list

36 total
Lower hazard (1) Higher hazard (4)
All36 Skin Conditioning27 Fragrance10 Masking9 Humectant8 Solvent6 Viscosity Controlling6 Antioxidant5 Binding4
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
4
Alcohol Denat.
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
Cocos Nucifera Fruit Juice
(Hair Conditioning, Humectant, Skin Conditioning, Skin Conditioning Emollient)
1
A
Hydrolyzed Collagen
(Hair Conditioning, Nail Conditioning Agent, Skin Conditioning, Antistatic Agent, Emollient, Film Forming, Humectant)
1
Mannitol
(Binding Agent, Flavoring Agent, Humectant, Binding, Masking, Moisturising, Skin Conditioning)
1
Gluconolactone
(Fragrance, Humectant, Solvent)
1
Caffeine
(Fragrance, Skin Conditioning, Masking)
1
Superoxide Dismutase
(Reducing, Skin Conditioning, Antioxidant)
1
Phenyl t-Butylnitrone
(Antioxidant)
1
Waltheria Indica Leaf Extract
(Skin Conditioning)
1
Glutathione
(Fragrance, Reducing)
Hamamelis Virginiana Water
(Astringent, Hair Conditioning, Skin Conditioning, Soothing)
1
Polygonum Cuspidatum Extract
(Cosmetic Astringent, Skin Conditioning)
1
Silybum Marianum Extract
(Skin Conditioning)
1
Acetyl Hexapeptide-1
(Skin Conditioning)
1
A
Dextran
(Binding Agent, Bulking Agent, Binding, Viscosity Controlling)
Citrus Paradisi Peel Oil
(Fragrance, Perfuming)
Cupressus Sempervirens Leaf/Nut/Stem Oil
(Emollient, Masking, Skin Conditioning)
1
Totarol
(Antioxidant, Deodorant, Oral Care Agent)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
A
Sodium Gluconate
(Chelating Agent, Skin Conditioning)
3
A
Sodium Benzoate
(Fragrance, Preservative, Anticorrosive, Masking)
3
A
Potassium Sorbate
(Fragrance, Preservative)
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
2
A
Citric Acid
(Chelating Agent, Fragrance, Ph Adjuster, Buffering Agent, Masking)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Sodium Citrate
(Ph Adjuster, Buffering Agent, Chelating, Masking)
1
Acetyl Tributyl Citrate
(Fragrance, Plasticizer, Film Forming, Masking, Perfuming)
1
Astaxanthin
(Cosmetic Colorant, Skin Conditioning)
1
Quercetin
(Antioxidant, Skin Conditioning)
1
A
Dextrin
(Absorbent, Binding Agent, Bulking Agent, Viscosity Increasing Agent, Binding, Viscosity Controlling)
2
Ferulic Acid
(Antioxidant, Preservative, Uv Absorber, Antimicrobial)
2
Alcohol
(Antifoaming Agent, Antimicrobial, Astringent, Masking, Solvent, Viscosity Controlling)
Bad for Dry Skin
Bad for Dry Skin
Bad for Sensitive Skin
Bad for Sensitive Skin
2
A
Isopropyl Alcohol
(Antifoaming Agent, Fragrance, Solvent, Viscosity Decreasing Agent, Perfuming, Viscosity Controlling)
Bad for Sensitive Skin
Bad for Sensitive Skin
1
A
Calcium Gluconate
(Skin Conditioning, Humectant, Oral Care Agent)

My Ingredient Notes

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Key ingredients

Antioxidants
Shields skin from free radical damage.
PHA
Gently exfoliates and hydrates with less irritation.
Peptides
Supports skin hydration and improves firmness.

Benefits

Anti-AgingSoftens lines and helps skin look youthful.
BrighteningRestores radiance to dull, tired skin.
HydratingBoosts hydration and relieves dry, tight skin.
Redness ReducingSoothes visible redness and calms irritation.
Scar HealingImproves the look of marks and scars.
Reduces IrritationEases discomfort and supports skin resilience.
Acne FightingFights acne and helps prevent breakouts.
Good For Oily SkinBalances oil and helps reduce shine.

Concerns

Not fungal acne (malassezia) safe
May not suit dry skin
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Cocos Nucifera Fruit Juice
Hair conditioning, Humectant
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningHumectantSkin conditioningSkin conditioning emollient
Hydrolyzed Collagen
Hair conditioning, Nail conditioning agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningNail conditioning agentSkin conditioningAntistatic agentEmollientFilm formingHumectant
Mannitol
Binding agent, Flavoring agent
Low-hazard ingredient.Read moreShow less
EWG 1 Binding agentFlavoring agentHumectantBindingMaskingMoisturisingSkin conditioning
Gluconolactone
Fragrance, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceHumectantSolvent
Caffeine
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceSkin conditioningMasking
Superoxide Dismutase
Reducing, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 ReducingSkin conditioningAntioxidant
Phenyl t-Butylnitrone
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
Waltheria Indica Leaf Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Glutathione
Fragrance, Reducing
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceReducing
Hamamelis Virginiana Water
Astringent, Hair conditioning
Limited public safety data.Read moreShow less
EWG N/A AstringentHair conditioningSkin conditioningSoothing
Polygonum Cuspidatum Extract
Cosmetic astringent, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Cosmetic astringentSkin conditioning
Silybum Marianum Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Acetyl Hexapeptide-1
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Dextran
Binding agent, Bulking agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentBulking agentBindingViscosity controlling
+ 15 more — see the full ingredients list above
Alcohol Denat.
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 4 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Citric Acid
Chelating agent, Fragrance
Skin irritation can occur at high concentrationRead moreShow less
EWG 2 CIR A Chelating agentFragrancePh adjusterBuffering agentMasking Bad for Sensitive Skin
Alcohol
Antifoaming agent, Antimicrobial
Causes moisture evaporation - prone to dry out skinRead moreShow less
EWG 2 Antifoaming agentAntimicrobialAstringentMaskingSolventViscosity controlling Bad for Dry SkinBad for Sensitive Skin
Isopropyl Alcohol
Antifoaming agent, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A Antifoaming agentFragranceSolventViscosity decreasing agentPerfumingViscosity controlling Bad for Sensitive Skin

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning only: Apply as the last step of your AM routine, after moisturiser, and reapply every ~2 hours of sun exposure.

General guidance from this product's category and active ingredients — always follow the directions on the package.

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