6-Week Perfection Neck Cream

DefenAge

Where to buy Possibly in stock

About this product

The DefenAge 6-Week Perfection Neck Cream is a moisturizer. Our analysis of its 39 ingredients (36 low-risk) rates it Excellent (100/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Moisturizers
Ingredients
39
Low-risk
36
Fragrance
Fragrance-free
Origin
United States
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 10/7
Good for dry skin
Methyl Glucose Sesquistearate Cetyl Alcohol Squalane Stearyl Alcohol Alanyl Glutamine Caprylic/Capric Triglyceride Butylene Glycol Glycerin Palmitic Acid Serum Albumin
Caution for dry skin
Cetyl Alcohol Sodium Stearoyl Glutamate Stearyl Alcohol Xanthan Gum Glycerin Palmitic Acid Polysorbate 20
Oily/Acne-Prone Skin No data
Sensitive Skin 4/8
Good for sensitive skin
Alpha-Arbutin Ubiquinone Glycerin Tocopheryl Acetate
Caution for sensitive skin
Cetyl Alcohol Sodium Chloride Stearyl Alcohol Caprylic/Capric Triglyceride Butylene Glycol Glycerin Palmitic Acid Sorbic Acid

Ingredients list

39 total
Lower hazard (1) Higher hazard (3)
All39 Skin Conditioning32 Viscosity Controlling9 Emulsion Stabilising9 Hair Conditioning8 Solvent7 Emollient7 Viscosity Increasing Agent6 Humectant6
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
Butyrospermum Parkii Butter
(Skin Conditioning, Viscosity Controlling)
1
C13-15 Alkane
(Solvent)
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Cetyl Alcohol
(Emulsion Stabilising, Fragrance, Opacifying, Emulsifying, Surfactant, Foam Boosting, Viscosity Increasing Agent, Emollient, Masking, Viscosity Controlling)
1
A
Phospholipids
(Skin Conditioning)
1
Alpha-Arbutin
(Antioxidant, Skin Conditioning)
1
A
Stearyl Alcohol
(Emulsion Stabilising, Fragrance, Emulsifying, Surfactant, Foambooster, Viscosity Increasing Agent, Emollient, Foam Boosting, Masking, Opacifying, Refatting, Viscosity Controlling)
SIMMONDSIA CHINENSIS SEED OIL
(Hair Conditioning, Skin Conditioning, Skin Conditioning Emollient)
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
Leontopodium Alpinum Callus Culture Extract
(Antioxidant, Hair Conditioning, Humectant, Skin Protecting)
1
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
(Skin Conditioning)
1
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
(Skin Conditioning)
1
A
Palmitoyl Tripeptide-1
(Skin Conditioning)
1
A
Palmitoyl Tetrapeptide-7
(Skin Conditioning)
1
Sea Whip Extract
(Skin Conditioning)
1
Ubiquinone
(Antioxidant, Skin Conditioning)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
2
Serum Albumin
(Film Forming, Hair Conditioning, Skin Conditioning, Humectant)
1
Alanyl Glutamine
(Humectant, Skin Conditioning, Emollient)
1
A
Palmitic Acid
(Fragrance, Opacifying, Sufactant, Surfactant Emulsifying Agentsurfactant Cleansing Agent Is Included As A Function For The Soap Form Of Palmitic Acid., Emollient)
Bad for Oily Skin
Bad for Oily Skin
Fungal Acne
Fungal Acne Trigger
1
B
Sodium Stearoyl Glutamate
(Hair Conditioning, Skin Conditioning, Surfactant Cleansingagent, Emulsifying)
1
A
Methyl Glucose Sesquistearate
(Skin Conditioning, Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
Polyacrylate Crosspolymer-6
(Emulsion Stabilising, Viscosity Controlling)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
1
Phytic Acid
(Chelating Agent, Oral Care Agent)
1
Sodium Phytate
(Chelating Agent, Oral Care Agent)
1
Leuconostoc/Radish Root Ferment Filtrate
(Antidandruff Agent, Antimicrobial)
1
Caprylhydroxamic Acid
(Chelating Agent)
1
A
1,2-Hexanediol
(Solvent)
3
A
Sorbic Acid
(Fragrance, Preservative)
1
Sodium Chloride
(Bulking Agent, Masking, Oral Care Agent, Viscosity Controlling)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Peptides
Supports skin hydration and improves firmness.
Antioxidants
Shields skin from free radical damage.
Vitamin E
Protects skin and soothes irritation.
Niacinamide
Strengthens, smooths, and brightens skin.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Scar HealingImproves the look of marks and scars.
Anti-AgingSoftens lines and helps skin look youthful.
Skin TextureSmooths rough patches and refines texture.
BrighteningRestores radiance to dull, tired skin.
Reduces IrritationEases discomfort and supports skin resilience.
Redness ReducingSoothes visible redness and calms irritation.

Concerns

Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Butyrospermum Parkii Butter
Skin conditioning, Viscosity controlling
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningViscosity controlling
C13-15 Alkane
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Propanediol
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Cetyl Alcohol
Emulsion stabilising, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingFragranceOpacifyingEmulsifyingSurfactantFoam boostingViscosity increasing agentEmollientMaskingViscosity controlling
Phospholipids
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Alpha-Arbutin
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioning
Stearyl Alcohol
Emulsion stabilising, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingFragranceEmulsifyingSurfactant- foamboosterViscosity increasing agentEmollientFoam boostingMaskingOpacifyingRefattingViscosity controlling
SIMMONDSIA CHINENSIS SEED OIL
Hair conditioning, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Hair conditioningSkin conditioningSkin conditioning emollient
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Leontopodium Alpinum Callus Culture Extract
Antioxidant, Hair conditioning
Limited public safety data.Read moreShow less
EWG N/A AntioxidantHair conditioningHumectantSkin protecting
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
+ 17 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Palmitic Acid
Fragrance, Opacifying
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A FragranceOpacifyingSufactantSurfactant -emulsifying agentsurfactant-cleansing agent is included as a function for the soap form of palmitic acid.Emollient Bad for Oily SkinFungal-acne trigger
Methyl Glucose Sesquistearate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmollientEmulsifying Fungal-acne trigger
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin

How to use

How to use

  • 1 Where it fits: Apply near the end of your routine, after thinner serums.
  • 2 Morning & evening: Suitable for both AM and PM use.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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