Pro 24/7 Barrier Balance Cream

DefenAge

Where to buy Possibly in stock

About this product

The DefenAge Pro 24/7 Barrier Balance Cream is a moisturizer. Our analysis of its 37 ingredients (29 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry and sensitive skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Moisturizers
Ingredients
37
Low-risk
29
Fragrance
Fragrance-free
Origin
United States
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 7/3
Good for dry skin
Ophiopogon Japonicus Root Extract Squalane Alanyl Glutamine Caprylic/Capric Triglyceride Caprylyl Glycol Hyaluronic Acid Serum Albumin
Caution for dry skin
Xanthan Gum Hexylene Glycol Polysorbate 20
Oily/Acne-Prone Skin No data
Sensitive Skin 6/5
Good for sensitive skin
Lycium Chinense Fruit Extract Alpha-Arbutin Ubiquinone Tetrahexyldecyl Ascorbate Hydrolyzed Candida Saitoana Extract Tocopheryl Acetate
Caution for sensitive skin
Sodium Chloride Caprylic/Capric Triglyceride Hexylene Glycol Potassium Sorbate Phenoxyethanol

Ingredients list

37 total
Lower hazard (1) Higher hazard (4)
All37 Skin Conditioning36 Hair Conditioning5 Humectant5 Antioxidant5 Fragrance4 Emollient4 Viscosity Controlling4 Skin Protecting3
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
Carthamus Tinctorius Oleosomes
(Emulsion Stabilising, Skin Conditioning, Skin Conditioning Emollient)
Butyrospermum Parkii Butter
(Skin Conditioning, Viscosity Controlling)
1
Yeast Extract
(Skin Conditioning)
1
A
Macadamia Integrifolia Seed Oil
(Skin Conditioning)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling)
1
Alpha-Arbutin
(Antioxidant, Skin Conditioning)
1
A
Hyaluronic Acid
(Skin Conditioning, Viscosity Increasing Agent, Antistatic Agent, Humectant, Moisturising)
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
1
Sea Whip Extract
(Skin Conditioning)
1
Ophiopogon Japonicus Root Extract
(Humectant, Skin Conditioning, Tonic)
Vaccinium Angustifolium Fruit Extract
(Skin Protecting, Soothing)
1
Hydrolyzed Candida Saitoana Extract
(Skin Protecting)
1
Lycium Chinense Fruit Extract
(Antioxidant)
Vaccinium Macrocarpon Fruit Extract
(Astringent)
Helianthus Annuus Seed Oil
(Fragrance, Skin Conditioning, Skin Conditioning Emollient)
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
1
A
Phospholipids
(Skin Conditioning)
1
Alanyl Glutamine
(Humectant, Skin Conditioning, Emollient)
1
Ubiquinone
(Antioxidant, Skin Conditioning)
1
Tetrahexyldecyl Ascorbate
(Antioxidant, Skin Conditioning)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
Kappaphycus Alvarezii Extract
(Skin Conditioning)
Caesalpinia Spinosa Fruit Extract
(Skin Protecting)
1
Leuconostoc/Radish Root Ferment Filtrate
(Antidandruff Agent, Antimicrobial)
2
Serum Albumin
(Film Forming, Hair Conditioning, Skin Conditioning, Humectant)
1
A
Xanthan Gum
(Binding Agent, Emulsion Stabilising, Skin Conditioning, Surfactant Emulsifying Agent, Viscosity Increasing Agent, Binding, Gel Forming, Viscosity Controlling)
1
Phytic Acid
(Chelating Agent, Oral Care Agent)
3
B
Polysorbate 20
(Emulsifying, Surfactant)
Fungal Acne
Fungal Acne Trigger
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
1
A
Hexylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Emulsifying, Perfuming, Skin Conditioning, Surfactant)
3
A
Potassium Sorbate
(Fragrance, Preservative)
1
Sodium Chloride
(Bulking Agent, Masking, Oral Care Agent, Viscosity Controlling)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

Browse similar moisturizer
No close formula match yet — browse other products like this

Key ingredients

Antioxidants
Shields skin from free radical damage.
Vitamin C
Brightens, evens tone, and supports collagen.
Vitamin E
Protects skin and soothes irritation.
Niacinamide
Strengthens, smooths, and brightens skin.
Hyaluronic Acid
Hydrates by attracting and holding water.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Anti-AgingSoftens lines and helps skin look youthful.
Scar HealingImproves the look of marks and scars.
BrighteningRestores radiance to dull, tired skin.
Reduces IrritationEases discomfort and supports skin resilience.
Redness ReducingSoothes visible redness and calms irritation.
Reduces Large PoresMinimizes the look of enlarged pores.

Concerns

Contains paraben
Not fungal acne (malassezia) safe

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Carthamus Tinctorius Oleosomes
Emulsion stabilising, Skin conditioning
Limited public safety data.Read moreShow less
EWG N/A Emulsion stabilisingSkin conditioningSkin conditioning emollient
Butyrospermum Parkii Butter
Skin conditioning, Viscosity controlling
Limited public safety data.Read moreShow less
EWG N/A Skin conditioningViscosity controlling
Yeast Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Macadamia Integrifolia Seed Oil
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioning
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
Ammonium Acryloyldimethyltaurate/VP Copolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 Viscosity controlling
Alpha-Arbutin
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioning
Hyaluronic Acid
Skin conditioning, Viscosity increasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningViscosity increasing agentAntistatic agentHumectantMoisturising
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Sea Whip Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Ophiopogon Japonicus Root Extract
Humectant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantSkin conditioningTonic
Vaccinium Angustifolium Fruit Extract
Skin protecting, Soothing
Limited public safety data.Read moreShow less
EWG N/A Skin protectingSoothing
Hydrolyzed Candida Saitoana Extract
Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 Skin protecting
Lycium Chinense Fruit Extract
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
+ 18 more — see the full ingredients list above
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Polysorbate 20
Emulsifying, Surfactant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B EmulsifyingSurfactant Fungal-acne trigger
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben

How to use

How to use

  • 1 Where it fits: Apply near the end of your routine, after thinner serums.
  • 2 Morning works well: Antioxidants like vitamin C pair well with daytime use under sunscreen.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Tetrahexyldecyl Ascorbate

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

From the community

0
Reviews
0
Saved by users
0
In collections

Ratings & reviews

Write a Review
0.0
from 0 ratings

Used this product? Rate it in 10 seconds

Alternatives