Peptide Complex 10% Wrinkle Defense Serum

Depology

Peptide Complex 10% Wrinkle Defense Serum

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About this product

The Depology Peptide Complex 10% Wrinkle Defense Serum is a serums, essence, ampoule. Our analysis of its 33 ingredients (29 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
33
Low-risk
29
Fragrance
Fragrance-free
Origin
South Korea
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 6/4
Good for dry skin
Acetyl Hexapeptide-8 Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Glycerin Hydroxyethyl Urea
Caution for dry skin
Maltodextrin Centella Asiatica Extract Glycerin Hydrogenated Lecithin
Oily/Acne-Prone Skin No data
Sensitive Skin 4/5
Good for sensitive skin
Centella Asiatica Extract Ascorbic Acid Polypeptide Glycerin Tocopheryl Acetate
Caution for sensitive skin
Anthemis Nobilis Flower Oil Butylene Glycol Glycerin Tromethamine Linalool

Ingredients list

33 total
Lower hazard (1) Higher hazard (5)
All33 Skin Conditioning27 Humectant8 Solvent6 Hair Conditioning6 Fragrance6 Viscosity Controlling6 Emulsion Stabilising5 Masking4
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
Isopentyldiol
(Solvent)
1
A
1,2-Hexanediol
(Solvent)
1
A
Panthenol
(Antistatic Agent, Hair Conditioning, Skin Conditioning)
Good for Dry Skin
Good for Dry Skin
1
Hydroxyethyl Urea
(Hair Conditioning, Humectant, Skin Conditioning)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
Ficus Carica Fruit Extract
(Humectant)
1
B
Centella Asiatica Extract
(Cleansing, Skin Conditioning, Smoothing, Soothing, Tonic)
1
Acetyl Hexapeptide-8
(Humectant, Skin Conditioning)
1
Ceramide NP
(Hair Conditioning, Skin Conditioning)
2
A
Hydrogenated Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Suspending Agent Nonsurfactant)
1
Anthemis Nobilis Flower Oil
(Masking, Perfuming, Skin Conditioning)
Good for Sensitive Skin
Good for Sensitive Skin
Good for Dry Skin
Good for Dry Skin
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
1
Houttuynia Cordata Extract
(Skin Conditioning)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
Ascorbic Acid Polypeptide
(Antioxidant, Skin Conditioning)
1
Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling)
2
A
Tromethamine
(Fragrance, Ph Adjuster, Buffering Agent, Masking)
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
1
B
Octyldodeceth-16
(Emulsifying)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
1
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
Palmitoyl Tripeptide-5
(Skin Conditioning)
2
Pinus Strobus Bark Extract
(Skin Conditioning)
1
Hexapeptide-9
(Skin Conditioning)
1
A
Maltodextrin
(Absorbent, Binding Agent, Emulsion Stabilising, Film Forming, Hair Conditioning, Skin Conditioning, Suspending Agent Nonsurfactant, Binding)
lavandula angustifolia oil
(Fragrance, Tonic)
5
Linalool
(Fragrance, Deodorant, Masking)
Allergens
Allergens

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Peptides
Supports skin hydration and improves firmness.
Antioxidants
Shields skin from free radical damage.
Vitamin E
Protects skin and soothes irritation.
Vitamin C
Brightens, evens tone, and supports collagen.
Ceramides
Locks in moisture and supports skin barrier.
Hyaluronic Acid
Hydrates by attracting and holding water.
Show all 6 key ingredients

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Anti-AgingSoftens lines and helps skin look youthful.
Redness ReducingSoothes visible redness and calms irritation.
Reduces IrritationEases discomfort and supports skin resilience.
BrighteningRestores radiance to dull, tired skin.
Scar HealingImproves the look of marks and scars.
Dark SpotsFades dark spots for even skin tone.

Concerns

Contains eu allergen
Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Isopentyldiol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Hydroxyethyl Urea
Hair conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 Hair conditioningHumectantSkin conditioning
Propanediol
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
Ficus Carica Fruit Extract
Humectant
Limited public safety data.Read moreShow less
EWG N/A Humectant
Centella Asiatica Extract
Cleansing, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B CleansingSkin conditioningSmoothingSoothingTonic
Acetyl Hexapeptide-8
Humectant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 HumectantSkin conditioning
Ceramide NP
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Hair conditioningSkin conditioning
Hydrogenated Lecithin
Skin conditioning, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A Skin conditioningEmulsifyingSurfactantSuspending agent- nonsurfactant
TOCOPHEROL
Antioxidant, Fragrance
Limited public safety data.Read moreShow less
EWG N/A AntioxidantFragranceSkin conditioning
Houttuynia Cordata Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Ascorbic Acid Polypeptide
Antioxidant, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 AntioxidantSkin conditioning
Ammonium Acryloyldimethyltaurate/VP Copolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 Viscosity controlling
+ 11 more — see the full ingredients list above
Panthenol
Antistatic agent, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Antistatic agentHair conditioningSkin conditioning Good for Dry Skin
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Anthemis Nobilis Flower Oil
Masking, Perfuming
Low-hazard ingredient.Read moreShow less
EWG 1 MaskingPerfumingSkin conditioning Good for Sensitive SkinGood for Dry Skin
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Linalool
Fragrance, Deodorant
Moderate-hazard ingredient.Read moreShow less
EWG 5 FragranceDeodorantMasking Allergens

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Morning works well: Antioxidants like vitamin C pair well with daytime use under sunscreen.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Vitamin C (ascorbic) 5–20%

L-ascorbic acid is usually used at 5–20% (around 10–15% is common). Above ~20% adds little and tends to irritate more; it also needs a low pH to work.

Ascorbic Acid Polypeptide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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