Retilogy Retinal 0.1% Renewing Serum

Depology

Where to buy Possibly in stock

About this product

The Depology Retilogy Retinal 0.1% Renewing Serum is a serums, essence, ampoule. Our analysis of its 63 ingredients (52 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
63
Low-risk
52
Fragrance
Fragrance-free
Origin
South Korea
Data updated
Jun 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 18/12
Good for dry skin
Glycosyl Trehalose Macadamia Ternifolia Seed Oil Borago Officinalis Seed Oil Sucrose Distearate Squalane Acetyl Tetrapeptide-5 Caprylic/Capric Triglyceride Caprylyl Glycol Butylene Glycol Sodium Hyaluronate Glycerin Cholesterol Polyglyceryl-3 Methylglucose Distearate Polyquaternium-51 Fructooligosaccharides Hydrogenated Starch Hydrolysate Hydrolyzed Hyaluronic Acid Lecithin
Caution for dry skin
Glyceryl Stearate SE Microcrystalline Cellulose Centella Asiatica Extract Sucrose Distearate Glycerin Potassium Cetyl Phosphate Polyglyceryl-10 Laurate Polyglyceryl-3 Methylglucose Distearate Hydrogenated Lecithin Ceteareth-20 Silica Lecithin
Oily/Acne-Prone Skin No data
Sensitive Skin 9/10
Good for sensitive skin
Laminaria Japonica Extract Glycosyl Trehalose Centella Asiatica Extract Glycerin Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate Hydroxyacetophenone Camellia Sinensis Leaf Water Tocopheryl Acetate Phloretin
Caution for sensitive skin
Laminaria Japonica Extract Dipropylene Glycol Cellulose Gum Arginine Caprylic/Capric Triglyceride Butylene Glycol Glycerin Hydroxypropyl Cyclodextrin Camellia Sinensis Leaf Water Tromethamine

Ingredients list

63 total
Lower hazard (1) Higher hazard (6)
All63 Skin Conditioning54 Humectant13 Viscosity Controlling10 Emulsifying9 Emulsion Stabilising9 Emollient9 Surfactant8 Masking8
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
Methylpropanediol
(Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
1
A
Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling)
1
A
Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing)
1
A
1,2-Hexanediol
(Solvent)
1
A
Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling)
Good for Dry Skin
Good for Dry Skin
1
A
Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent)
1
Macadamia Ternifolia Seed Oil
(Emollient)
1
A
Hydroxypropyl Cyclodextrin
(Chelating Agent, Emulsion Stabilising, Masking, Skin Conditioning)
2
A
Hydrogenated Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Suspending Agent Nonsurfactant)
1
Hydroxyacetophenone
(Antioxidant)
1
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling)
1
Laminaria Japonica Extract
(Fragrance, Skin Protecting)
1
Eclipta Prostrata Leaf Extract
(Skin Conditioning)
1
A
Glyceryl Stearate SE
(Emulsifying, Surfactant)
Bad for Oily Skin
Bad for Oily Skin
2
A
Tromethamine
(Fragrance, Ph Adjuster, Buffering Agent, Masking)
1
A
Microcrystalline Cellulose
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Emulsion Stabilising, Slip Modifier, Viscosity Increasing Agent)
1
A
Cholesterol
(Emulsion Stabilising, Skin Conditioning, Viscosity Increasing Agent, Emollient, Emulsifying, Stabilising, Viscosity Controlling)
1
B
Polyglyceryl-10 Laurate
(Skin Conditioning, Emulsifying, Surfactant)
Dioscorea Japonica Root Extract
(Skin Conditioning)
1
Polyglyceryl-3 Methylglucose Distearate
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
1
A
Borago Officinalis Seed Oil
(Emollient, Skin Conditioning)
5
6
Retinal
(Skin Conditioning)
1
2
A
Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling)
Brassica Campestris Sterols
(Skin Conditioning, Skin Conditioning Emollient)
3
Tocopheryl Acetate
(Antioxidant, Skin Conditioning)
Bad for Oily Skin
Bad for Oily Skin
1
Acetyl Tetrapeptide-5
(Humectant)
1
Acetyl Hexapeptide-1
(Skin Conditioning)
1
Acetyl Tetrapeptide-2
(Skin Conditioning)
1
Glycosyl Trehalose
(Binding Agent, Emulsion Stabilising, Film Forming, Humectant, Skin Protecting)
1
Fructooligosaccharides
(Humectant, Skin Conditioning)
1
Aluminum/Magnesium Hydroxide Stearate
(Emulsion Stabilising, Viscosity Controlling)
TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning)
1
A
Hydrogenated Starch Hydrolysate
(Humectant, Oral Care Agent)
1
A
Beta-Glucan
(Bulking Agent, Skin Conditioning)
Raffinose
(Skin Conditioning)
1
Sucrose Distearate
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
1
Adenosine
(Skin Conditioning)
1
A
Cellulose Gum
(Binding Agent, Emulsion Stabilising, Film Forming, Fragrance, Viscosity Increasing Agent, Binding, Masking, Viscosity Controlling)
1
B
Potassium Cetyl Phosphate
(Emulsifying, Surfactant)
3
B
Ceteareth-20
(Cleansing, Emulsifying, Surfactant)
1
Polyquaternium-51
(Film Forming, Humectant, Skin Conditioning)
1
A
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
(Antioxidant)
Avena sativa Kernel Extract
(Abrasive, Antioxidant, Skin Conditioning, Skin Conditioning Emollient)
Cynara Scolymus Leaf Extract
(Skin Conditioning)
2
3
Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient)
1
B
Camellia Sinensis Leaf Water
(Masking, Perfuming, Tonic)
Good for Oily Skin
Good for Oily Skin
Ficus Carica Fruit Extract
(Humectant)
1
B
Centella Asiatica Extract
(Cleansing, Skin Conditioning, Smoothing, Soothing, Tonic)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
Hydrolyzed Hyaluronic Acid
(Hair Conditioning, Humectant, Skin Conditioning)
1
A
Biosaccharide Gum-1
(Skin Conditioning)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling)
Glycine Soja Seed Extract
(Skin Conditioning)
1
A
Ethylhexylglycerin
(Deodorant, Skin Conditioning)
Tetrahydropiperine
(Skin Conditioning)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
Phloretin
(Antioxidant, Antiseborrhoeic)
1
A
Arginine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Antioxidants
Shields skin from free radical damage.
Peptides
Supports skin hydration and improves firmness.
Vitamin E
Protects skin and soothes irritation.
Hyaluronic Acid
Hydrates by attracting and holding water.
Exfoliators
Removes dead skin cells to smoothe texture.
Retinoid
Visibly reduces the signs of aging.
Niacinamide
Strengthens, smooths, and brightens skin.
Show all 7 key ingredients

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Reduces IrritationEases discomfort and supports skin resilience.
Redness ReducingSoothes visible redness and calms irritation.
Anti-AgingSoftens lines and helps skin look youthful.
Scar HealingImproves the look of marks and scars.
BrighteningRestores radiance to dull, tired skin.
Dark SpotsFades dark spots for even skin tone.

Concerns

Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Methylpropanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Dipropylene Glycol
Fragrance, Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSolventViscosity decreasing agentMaskingViscosity controlling
Niacinamide
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningSmoothing
1,2-Hexanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Solvent
Caprylic/Capric Triglyceride
Emollient, Masking
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientMaskingPerfumingSkin conditioningSolvent
Macadamia Ternifolia Seed Oil
Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 Emollient
Hydroxypropyl Cyclodextrin
Chelating agent, Emulsion stabilising
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentEmulsion stabilisingMaskingSkin conditioning
Hydrogenated Lecithin
Skin conditioning, Emulsifying
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A Skin conditioningEmulsifyingSurfactantSuspending agent- nonsurfactant
Hydroxyacetophenone
Antioxidant
Low-hazard ingredient.Read moreShow less
EWG 1 Antioxidant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion stabilising, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 Emulsion stabilisingFilm formingViscosity controlling
Laminaria Japonica Extract
Fragrance, Skin protecting
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceSkin protecting
Eclipta Prostrata Leaf Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Tromethamine
Fragrance, Ph adjuster
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A FragrancePh adjusterBuffering agentMasking
+ 41 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Butylene Glycol
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceSkin conditioningSolventViscositydecreasing agentHumectantMaskingViscosity controlling Good for Dry Skin
Glyceryl Stearate SE
Emulsifying, Surfactant
Potentially comedogenic - can block poresRead moreShow less
EWG 1 CIR A EmulsifyingSurfactant Bad for Oily Skin
Retinal
Skin conditioning
Moderate-hazard ingredient.Read moreShow less
EWG 5–6 Skin conditioning
Tocopheryl Acetate
Antioxidant, Skin conditioning
Potentially comedogenic - can block poresRead moreShow less
EWG 3 AntioxidantSkin conditioning Bad for Oily Skin
Camellia Sinensis Leaf Water
Masking, Perfuming
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B MaskingPerfumingTonic Good for Oily Skin
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening: Use at night — start 2–3× a week and build up as your skin tolerates it.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Pregnancy & breastfeeding

Contains ingredients some choose to avoid or double-check while pregnant or nursing.

Often avoided
Retinoids (Vitamin A) (Retinal)

Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.

This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

Retinoids (Vitamin A) 0.01–1%

Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.

Retinal

Niacinamide 2–5% (up to 10%)

Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.

Niacinamide

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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