Retilogy Retinal 0.1% Renewing Serum
The Depology Retilogy Retinal 0.1% Renewing Serum is a serums, essence, ampoule. Our analysis of its 63 ingredients (52 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin.
The Depology Retilogy Retinal 0.1% Renewing Serum is a serums, essence, ampoule. Our analysis of its 63 ingredients (52 low-risk) rates it Excellent (99/100). Based on its ingredients, it looks well-suited to dry skin.
Summarised from our ingredient analysis — not brand marketing copy.
The evidence
| EWG | CIR | Ingredient Name & Cosmetic Functions | Notes |
|---|---|---|---|
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Water
(Solvent) |
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Methylpropanediol
(Solvent) |
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Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent) |
Good for Dry Skin
Fungal Acne Trigger
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Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning) |
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Dipropylene Glycol
(Fragrance, Solvent, Viscosity Decreasing Agent, Masking, Viscosity Controlling) |
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Niacinamide
(Hair Conditioning, Skin Conditioning, Smoothing) |
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1,2-Hexanediol
(Solvent) |
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Butylene Glycol
(Fragrance, Skin Conditioning, Solvent, Viscositydecreasing Agent, Humectant, Masking, Viscosity Controlling) |
Good for Dry Skin
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Caprylic/Capric Triglyceride
(Emollient, Masking, Perfuming, Skin Conditioning, Solvent) |
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Macadamia Ternifolia Seed Oil
(Emollient) |
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Hydroxypropyl Cyclodextrin
(Chelating Agent, Emulsion Stabilising, Masking, Skin Conditioning) |
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Hydrogenated Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Suspending Agent Nonsurfactant) |
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Hydroxyacetophenone
(Antioxidant) |
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Acrylates/C10-30 Alkyl Acrylate Crosspolymer
(Emulsion Stabilising, Film Forming, Viscosity Controlling) |
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Laminaria Japonica Extract
(Fragrance, Skin Protecting) |
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Eclipta Prostrata Leaf Extract
(Skin Conditioning) |
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Glyceryl Stearate SE
(Emulsifying, Surfactant) |
Bad for Oily Skin
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Tromethamine
(Fragrance, Ph Adjuster, Buffering Agent, Masking) |
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Microcrystalline Cellulose
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Emulsion Stabilising, Slip Modifier, Viscosity Increasing Agent) |
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Cholesterol
(Emulsion Stabilising, Skin Conditioning, Viscosity Increasing Agent, Emollient, Emulsifying, Stabilising, Viscosity Controlling) |
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Polyglyceryl-10 Laurate
(Skin Conditioning, Emulsifying, Surfactant) |
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Dioscorea Japonica Root Extract
(Skin Conditioning) |
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Polyglyceryl-3 Methylglucose Distearate
(Skin Conditioning, Emollient, Emulsifying, Surfactant) |
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Borago Officinalis Seed Oil
(Emollient, Skin Conditioning) |
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Retinal
(Skin Conditioning) |
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Silica
(Abrasive, Absorbent, Anticaking Agent, Bulking Agent, Opacifying, Viscosity Controlling) |
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Brassica Campestris Sterols
(Skin Conditioning, Skin Conditioning Emollient) |
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Tocopheryl Acetate
(Antioxidant, Skin Conditioning) |
Bad for Oily Skin
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Acetyl Tetrapeptide-5
(Humectant) |
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Acetyl Hexapeptide-1
(Skin Conditioning) |
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Acetyl Tetrapeptide-2
(Skin Conditioning) |
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Glycosyl Trehalose
(Binding Agent, Emulsion Stabilising, Film Forming, Humectant, Skin Protecting) |
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Fructooligosaccharides
(Humectant, Skin Conditioning) |
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Aluminum/Magnesium Hydroxide Stearate
(Emulsion Stabilising, Viscosity Controlling) |
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TOCOPHEROL
(Antioxidant, Fragrance, Skin Conditioning) |
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Hydrogenated Starch Hydrolysate
(Humectant, Oral Care Agent) |
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Beta-Glucan
(Bulking Agent, Skin Conditioning) |
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Raffinose
(Skin Conditioning) |
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Sucrose Distearate
(Skin Conditioning, Emollient, Emulsifying, Surfactant) |
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Adenosine
(Skin Conditioning) |
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Cellulose Gum
(Binding Agent, Emulsion Stabilising, Film Forming, Fragrance, Viscosity Increasing Agent, Binding, Masking, Viscosity Controlling) |
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Potassium Cetyl Phosphate
(Emulsifying, Surfactant) |
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Ceteareth-20
(Cleansing, Emulsifying, Surfactant) |
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Polyquaternium-51
(Film Forming, Humectant, Skin Conditioning) |
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Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
(Antioxidant) |
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Avena sativa Kernel Extract
(Abrasive, Antioxidant, Skin Conditioning, Skin Conditioning Emollient) |
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Cynara Scolymus Leaf Extract
(Skin Conditioning) |
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Lecithin
(Skin Conditioning, Emulsifying, Surfactant, Antistatic Agent, Emollient) |
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Camellia Sinensis Leaf Water
(Masking, Perfuming, Tonic) |
Good for Oily Skin
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Ficus Carica Fruit Extract
(Humectant) |
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Centella Asiatica Extract
(Cleansing, Skin Conditioning, Smoothing, Soothing, Tonic) |
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Sodium Hyaluronate
(Skin Conditioning, Humectant) |
Good for Dry Skin
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Hydrolyzed Hyaluronic Acid
(Hair Conditioning, Humectant, Skin Conditioning) |
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Biosaccharide Gum-1
(Skin Conditioning) |
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Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant) |
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Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling) |
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Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling) |
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Glycine Soja Seed Extract
(Skin Conditioning) |
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Ethylhexylglycerin
(Deodorant, Skin Conditioning) |
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Tetrahydropiperine
(Skin Conditioning) |
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Disodium EDTA
(Chelating Agent, Viscosity Controlling) |
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Phloretin
(Antioxidant, Antiseborrhoeic) |
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Arginine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking) |
No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.
How to use
General guidance from this product's category and active ingredients — always follow the directions on the package.
Trust & honesty
Contains ingredients some choose to avoid or double-check while pregnant or nursing.
Topical retinoids (retinol, retinaldehyde, retinyl esters) are widely advised against in pregnancy as a precaution. The strongest evidence is for ORAL retinoids; topical absorption is low, but most clinicians err on the side of caution.
This is general information, not medical advice. Pregnancy guidance varies and depends on concentration and your individual situation — always check with your doctor, midwife or pharmacist. How we flag this.
The concentrations these actives are typically effective at in research — not a measurement of this product.
Most studied between 0.1% and 1%. Higher is not automatically better — irritation climbs with dose, so a well-formulated lower strength is often the sweet spot.
Retinal
Most research uses 2–5%; some formulas go to 10%. Very high levels can cause flushing in sensitive skin.
Niacinamide
INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.
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