Defensia Serum

Dermina

Where to buy Possibly in stock

About this product

The Dermina Defensia Serum is a serums, essence, ampoule. Our analysis of its 26 ingredients (25 low-risk) rates it Excellent (98/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Serums, Essence, Ampoules
Ingredients
26
Low-risk
25
Fragrance
Fragrance-free
Origin
France
Data updated
May 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 6/2
Good for dry skin
Betaine Caprylyl Glycol Sodium Hyaluronate Glycerin Trehalose Urea
Caution for dry skin
Glycerin Sodium Hydroxide
Oily/Acne-Prone Skin No data
Sensitive Skin 1/7
Good for sensitive skin
Glycerin
Caution for sensitive skin
Disodium Phosphate Levulinic Acid Hippophae Rhamnoides Extract Serine Algin Glycerin Malic Acid

Ingredients list

26 total
Lower hazard (1) Higher hazard (4)
All26 Skin Conditioning16 Humectant9 Fragrance6 Solvent5 Viscosity Controlling5 Buffering Agent5 Ph Adjuster4 Masking4
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
Water
(Solvent)
1
Propanediol
(Solvent, Viscosity Decreasing Agent, Viscosity Controlling)
1
Methylpropanediol
(Solvent)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
3
A
Glyceryl Polyacrylate
(Film Forming)
1
Nymphaea Alba Flower Extract
(Skin Conditioning, Tonic)
1
Nymphaea Alba Root Extract
(Skin Conditioning)
1
Hippophae Rhamnoides Extract
(Masking, Skin Conditioning)
3
A
Urea
(Buffering Agent, Humectant, Antistatic Agent, Skin Conditioning)
1
B
Betaine
(Hair Conditioning, Humectant, Antistatic Agent, Skin Conditioning, Viscosity Controlling)
1
A
Trehalose
(Flavoring Agent, Humectant, Moisturising)
1
A
Sodium Hyaluronate
(Skin Conditioning, Humectant)
Good for Dry Skin
Good for Dry Skin
1
A
Serine
(Fragrance, Hair Conditioning, Skin Conditioning, Antistatic Agent, Masking)
1
A
Algin
(Binding Agent, Fragrance, Viscosity Increasing Agent, Binding, Masking, Viscosity Controlling)
Bad for Sensitive Skin
Bad for Sensitive Skin
Bad for Oily Skin
Bad for Oily Skin
1
A
Pullulan
(Binding Agent, Film Forming, Binding)
1
A
Caprylyl Glycol
(Hair Conditioning, Skin Conditioning, Emollient, Humectant)
1
Ammonium Acryloyldimethyltaurate/VP Copolymer
(Viscosity Controlling)
1
Levulinic Acid
(Fragrance, Skin Conditioning, Perfuming)
1
Sodium Levulinate
(Skin Conditioning)
1
A
Pentylene Glycol
(Skin Conditioning, Solvent)
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
3
4
B
Malic Acid
(Fragrance, Ph Adjuster, Buffering Agent)
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
1
B
Disodium Phosphate
(Buffering Agent, Anticorrosive, Fragrance, Ph Adjuster, Masking)
1
B
Potassium Phosphate
(Ph Adjuster, Buffering Agent)
2
A
Chlorphenesin
(Cosmetic Biocide, Antimicrobial, Preservative)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Hyaluronic Acid
Hydrates by attracting and holding water.
Urea
Gently exfoliates and deeply moisturizes.

Benefits

HydratingBoosts hydration and relieves dry, tight skin.
Barrier RepairStrengthen and restore your skin's natural barrier.
Anti-AgingSoftens lines and helps skin look youthful.
Reduces IrritationEases discomfort and supports skin resilience.
Redness ReducingSoothes visible redness and calms irritation.
Scar HealingImproves the look of marks and scars.
Skin TextureSmooths rough patches and refines texture.
Show all 7 benefits

Concerns

Not fungal acne (malassezia) safe
May not suit sensitive skin

Ingredients explained

Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Propanediol
Solvent, Viscosity decreasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 SolventViscosity decreasing agentViscosity controlling
Methylpropanediol
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Glyceryl Polyacrylate
Film forming
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Film forming
Nymphaea Alba Flower Extract
Skin conditioning, Tonic
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioningTonic
Nymphaea Alba Root Extract
Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 Skin conditioning
Hippophae Rhamnoides Extract
Masking, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 MaskingSkin conditioning
Urea
Buffering agent, Humectant
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Buffering agentHumectantAntistatic agentSkin conditioning
Betaine
Hair conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR B Hair conditioningHumectantAntistatic agentSkin conditioningViscosity controlling
Trehalose
Flavoring agent, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Flavoring agentHumectantMoisturising
Serine
Fragrance, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A FragranceHair conditioningSkin conditioningAntistatic agentMasking
Pullulan
Binding agent, Film forming
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentFilm formingBinding
Caprylyl Glycol
Hair conditioning, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Hair conditioningSkin conditioningEmollientHumectant
Ammonium Acryloyldimethyltaurate/VP Copolymer
Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 Viscosity controlling
Levulinic Acid
Fragrance, Skin conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 FragranceSkin conditioningPerfuming
+ 8 more — see the full ingredients list above
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Sodium Hyaluronate
Skin conditioning, Humectant
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningHumectant Good for Dry Skin
Algin
Binding agent, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Binding agentFragranceViscosity increasing agentBindingMaskingViscosity controlling Bad for Sensitive SkinBad for Oily Skin

How to use

How to use

  • 1 Where it fits: Apply after toner and before moisturiser — thinnest to thickest.
  • 2 Evening, start slow: Best in the PM a few times a week to begin with; avoid layering with other strong actives the same night.
  • 3 Wear SPF the next day: Acids and retinoids increase sun sensitivity — daily sunscreen is a must while using this.

General guidance from this product's category and active ingredients — always follow the directions on the package.

Trust & honesty

Effective levels — general guide

The concentrations these actives are typically effective at in research — not a measurement of this product.

AHA (acid exfoliant) 5–10% (OTC)

OTC leave-on AHAs are usually 5–10%. The effect also depends on pH and free-acid value, not the percentage alone.

Malic Acid

INCI lists don't disclose amounts, and we don't claim to know this product's levels — these are the ranges these ingredients are usually effective at, so you can tell a real formula from "fairy-dusting" a marketed active. How we estimate this.

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