0.1% w/w Cream

Differin

Where to buy Possibly in stock

About this product

The Differin 0.1% w/w Cream is a misc. Our analysis of its 12 ingredients (9 low-risk) rates it Excellent (84/100). Based on its ingredients, it looks well-suited to dry skin.

Vegan-friendly Reef-safe

Summarised from our ingredient analysis — not brand marketing copy.

At a glance

Type
Misc
Ingredients
12
Low-risk
9
Fragrance
Fragrance-free
Origin
United States
Status
Discontinued
Data updated
May 2026

The evidence

Quick Product Notes

Paraben-Free Sulfate-Free Alcohol-Free Silicone-Free EU Allergen-Free Fungal Acne (Malassezia) Safe Minimal Ingredients

Notable Effects & Ingredients

No Notable Effects & Ingredients

Ingredients Related to Skin Types

Good   Bad — tap a skin type to see which ingredients · estimated from ingredient functions
Dry Skin 5/3
Good for dry skin
Methyl Glucose Sesquistearate Squalane Glycerin Cyclomethicone PEG-20 Methyl Glucose Sesquistearate
Caution for dry skin
Glycerin Sodium Hydroxide PEG-20 Methyl Glucose Sesquistearate
Oily/Acne-Prone Skin No data
Sensitive Skin 1/4
Good for sensitive skin
Glycerin
Caution for sensitive skin
Glycerin Methylparaben Phenoxyethanol Propylparaben

Ingredients list

12 total
Lower hazard (1) Higher hazard (7)
All12 Skin Conditioning4 Emollient4 Fragrance4 Solvent3 Preservative3 Viscosity Controlling3 Humectant3 Hair Conditioning3
EWG CIR Ingredient Name & Cosmetic Functions Notes
1
A
Carbomer
(Emulsion Stabilising, Viscosity Increasing Agent, Gel Forming, Viscosity Controlling)
3
A
PEG-20 Methyl Glucose Sesquistearate
(Skin Conditioning, Emollient, Emulsifying, Surfactant)
2
A
Glycerin
(Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care Agent, Oral Health Care Drug, Skin Protecting, Viscosity Decreasing Agent, Perfuming, Solvent)
Good for Dry Skin
Good for Dry Skin
Fungal Acne
Fungal Acne Trigger
1
A
Squalane
(Emollient, Hair Conditioning, Refatting, Skin Conditioning)
4
A
Methylparaben
(Fragrance, Preservative)
Paraben
Paraben
7
A
Propylparaben
(Fragrance, Preservative, Perfuming)
Paraben
Paraben
1
A
Disodium EDTA
(Chelating Agent, Viscosity Controlling)
1
A
Methyl Glucose Sesquistearate
(Skin Conditioning, Emollient, Emulsifying)
Fungal Acne
Fungal Acne Trigger
4
A
Phenoxyethanol
(Fragrance, Preservative)
Paraben
Paraben
2
A
Cyclomethicone
(Antistatic Agent, Emollient, Hair Conditioning, Humectant, Solvent, Viscosity Controlling)
Silicone
Silicone
3
B
Sodium Hydroxide
(Denaturant, Ph Adjuster, Buffering Agent)
1
Water
(Solvent)

My Ingredient Notes

No personal ingredient notes yet. Save ingredients to your profile to get good/bad alerts here.

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Key ingredients

Retinoid
Visibly reduces the signs of aging.

Benefits

Anti-AgingSoftens lines and helps skin look youthful.
HydratingBoosts hydration and relieves dry, tight skin.
Scar HealingImproves the look of marks and scars.
Barrier RepairStrengthen and restore your skin's natural barrier.
Acne FightingFights acne and helps prevent breakouts.
Good For Oily SkinBalances oil and helps reduce shine.
Reduces Large PoresMinimizes the look of enlarged pores.
Skin TextureSmooths rough patches and refines texture.

Concerns

Contains paraben
Contains silicone
Not fungal acne (malassezia) safe
Propylparaben — higher EWG
May not suit sensitive skin

EWG flags hazard, not real-world risk — ratings don't account for how much of an ingredient a product contains. Treat these as things to research, not verdicts. How we score →

Ingredients explained

Carbomer
Emulsion stabilising, Viscosity increasing agent
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Emulsion stabilisingViscosity increasing agentGel formingViscosity controlling
PEG-20 Methyl Glucose Sesquistearate
Skin conditioning, Emollient
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR A Skin conditioningEmollientEmulsifyingSurfactant
Squalane
Emollient, Hair conditioning
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A EmollientHair conditioningRefattingSkin conditioning
Disodium EDTA
Chelating agent, Viscosity controlling
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Chelating agentViscosity controlling
Sodium Hydroxide
Denaturant, Ph adjuster
Low-to-moderate hazard.Read moreShow less
EWG 3 CIR B DenaturantPh adjusterBuffering agent
Water
Solvent
Low-hazard ingredient.Read moreShow less
EWG 1 Solvent
Glycerin
Denaturant, Fragrance
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A DenaturantFragranceHair conditioningHumectantOral care agentOral health care drugSkin protectingViscosity decreasing agentPerfumingSolvent Good for Dry SkinFungal-acne trigger
Methylparaben
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Propylparaben
Fragrance, Preservative
Higher-hazard ingredient.Read moreShow less
EWG 7 CIR A FragrancePreservativePerfuming Paraben
Methyl Glucose Sesquistearate
Skin conditioning, Emollient
Low-hazard ingredient.Read moreShow less
EWG 1 CIR A Skin conditioningEmollientEmulsifying Fungal-acne trigger
Phenoxyethanol
Fragrance, Preservative
Low-to-moderate hazard.Read moreShow less
EWG 4 CIR A FragrancePreservative Paraben
Cyclomethicone
Antistatic agent, Emollient
Low-hazard ingredient.Read moreShow less
EWG 2 CIR A Antistatic agentEmollientHair conditioningHumectantSolventViscosity controlling Silicone

How to use

How to use

  • 1 Morning & evening: Suitable for both AM and PM use.

General guidance from this product's category and active ingredients — always follow the directions on the package.

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